메뉴 건너뛰기




Volumn 3, Issue 4, 2014, Pages 846-874

Animal models for influenza viruses: Implications for universal vaccine development

Author keywords

Heterosubtypic immunity; Influenza animal models; Influenza virus; Universal influenza virus vaccine

Indexed keywords

AMANTADINE; COMPLEMENT MEMBRANE ATTACK COMPLEX; FC RECEPTOR; GAMMA INTERFERON; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; INFLUENZA VACCINE; INFLUENZA VIRUS HEMAGGLUTININ; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; OSELTAMIVIR; PERAMIVIR; RECOMBINANT VACCINE; RIMANTADINE; TUMOR NECROSIS FACTOR ALPHA; VIRUS ANTIGEN; VIRUS LIKE PARTICLE VACCINE; VIRUS SIALIDASE; ZANAMIVIR;

EID: 85000542356     PISSN: None     EISSN: 20760817     Source Type: Journal    
DOI: 10.3390/pathogens3040845     Document Type: Review
Times cited : (86)

References (202)
  • 1
    • 34447299235 scopus 로고    scopus 로고
    • Orthomyxoviridae: The viruses and their replication
    • 6th ed.; Lippincott Williams & Wilkins: Philadelphia, PA, USA
    • Shaw, M.L.; Palese, P. Orthomyxoviridae: The viruses and their replication. In Fields Virology, 6th ed.; Lippincott Williams & Wilkins: Philadelphia, PA, USA, 2007; pp. 1647–1689.
    • (2007) Fields Virology , pp. 1647-1689
    • Shaw, M.L.1    Palese, P.2
  • 4
    • 0034051550 scopus 로고    scopus 로고
    • Global epidemiology of influenza: Past and present
    • Cox, N.J.; Subbarao, K. Global epidemiology of influenza: Past and present. Annu. Rev. Med. 2000, 51, 407–421.
    • (2000) Annu. Rev. Med , vol.51 , pp. 407-421
    • Cox, N.J.1    Subbarao, K.2
  • 5
    • 51449086295 scopus 로고    scopus 로고
    • The biology of influenza viruses
    • Bouvier, N.M.; Palese, P. The biology of influenza viruses. Vaccine 2008, 26, D49–D53.
    • (2008) Vaccine , vol.26 , pp. 49-53
    • Bouvier, N.M.1    Palese, P.2
  • 11
    • 84890965081 scopus 로고    scopus 로고
    • Universal influenza virus vaccines: Need for clinical trials
    • Krammer, F.; Palese, P. Universal influenza virus vaccines: Need for clinical trials. Nature Immunol. 2013, 15, 3–5.
    • (2013) Nature Immunol , vol.15 , pp. 3-5
    • Krammer, F.1    Palese, P.2
  • 12
    • 84894075244 scopus 로고    scopus 로고
    • Emergence in china of human disease due to avian influenza a(H10N8)—cause for concern
    • To, K.K.; Tsang, A.K.; Chan, J.F.; Cheng, V.C.; Chen, H.; Yuen, K.Y. Emergence in china of human disease due to avian influenza a(H10N8)—cause for concern? J. Infect. 2014, 68, 205–215.
    • (2014) J. Infect , vol.68 , pp. 205-215
    • To, K.K.1    Tsang, A.K.2    Chan, J.F.3    Cheng, V.C.4    Chen, H.5    Yuen, K.Y.6
  • 13
    • 79952162488 scopus 로고    scopus 로고
    • Animal models for influenza virus pathogenesis and transmission
    • Bouvier, N.M.; Lowen, A.C. Animal models for influenza virus pathogenesis and transmission. Viruses 2010, 2, 1530–1563
    • (2010) Viruses , vol.2 , pp. 1530-1563
    • Bouvier, N.M.1    Lowen, A.C.2
  • 14
    • 0027988832 scopus 로고
    • Receptor specificity in human, avian, and equine h2 and h3 influenza virus isolates
    • Connor, R.J.; Kawaoka, Y.; Webster, R.G.; Paulson, J.C. Receptor specificity in human, avian, and equine h2 and h3 influenza virus isolates. Virology 1994, 205, 17–23.
    • (1994) Virology , vol.205 , pp. 17-23
    • Connor, R.J.1    Kawaoka, Y.2    Webster, R.G.3    Paulson, J.C.4
  • 15
    • 0025620241 scopus 로고
    • Sialyloligosaccharides of the respiratory epithelium in the selection of human influenza virus receptor specificity
    • Baum, L.G.; Paulson, J.C. Sialyloligosaccharides of the respiratory epithelium in the selection of human influenza virus receptor specificity. Acta Histochem. Suppl. 1990, 40, 35–38.
    • (1990) Acta Histochem. Suppl , vol.40 , pp. 35-38
    • Baum, L.G.1    Paulson, J.C.2
  • 16
    • 52349119857 scopus 로고    scopus 로고
    • Clinical characteristics of 26 human cases of highly pathogenic avian influenza a (H5N1) virus infection in china
    • Yu, H.; Gao, Z.; Feng, Z.; Shu, Y.; Xiang, N.; Zhou, L.; Huai, Y.; Feng, L.; Peng, Z.; Li, Z. et al. Clinical characteristics of 26 human cases of highly pathogenic avian influenza a (H5N1) virus infection in china. PLoS One 2008, 3, e2985.
    • (2008) Plos One , vol.3 , pp. 2985
    • Yu, H.1    Gao, Z.2    Feng, Z.3    Shu, Y.4    Xiang, N.5    Zhou, L.6    Huai, Y.7    Feng, L.8    Peng, Z.9    Li, Z.10
  • 18
    • 0037038866 scopus 로고    scopus 로고
    • Induction of proinflammatory cytokines in human macrophages by influenza a (H5N1) viruses: A mechanism for the unusual severity of human disease?
    • Cheung, C.Y.; Poon, L.L.; Lau, A.S.; Luk, W.; Lau, Y.L.; Shortridge, K.F.; Gordon, S.; Guan, Y.; Peiris, J.S. Induction of proinflammatory cytokines in human macrophages by influenza a (H5N1) viruses: A mechanism for the unusual severity of human disease? Lancet 2002, 360, 1831–1837.
    • (2002) Lancet , vol.360 , pp. 1831-1837
    • Cheung, C.Y.1    Poon, L.L.2    Lau, A.S.3    Luk, W.4    Lau, Y.L.5    Shortridge, K.F.6    Gordon, S.7    Guan, Y.8    Peiris, J.S.9
  • 19
    • 43449131547 scopus 로고    scopus 로고
    • Pathology, molecular biology, and pathogenesis of avian influenza a (H5N1) infection in humans
    • Korteweg, C.; Gu, J. Pathology, molecular biology, and pathogenesis of avian influenza a (H5N1) infection in humans. Am. J. Pathol. 2008, 172, 1155–1170.
    • (2008) Am. J. Pathol , vol.172 , pp. 1155-1170
    • Korteweg, C.1    Gu, J.2
  • 20
    • 10944240992 scopus 로고    scopus 로고
    • Influenza: Old and new threats
    • Palese, P. Influenza: Old and new threats. Nat. Med. 2004, 10, S82–S87.
    • (2004) Nat. Med , vol.10 , pp. 82-87
    • Palese, P.1
  • 21
    • 77954162510 scopus 로고    scopus 로고
    • Available online:, (accessed on 10 October)
    • WHO. Influenza (seasonal); Available online: http://www.who.int/mediacentre/factsheets/fs211/en (accessed on 10 October 2014).
    • (2014) Influenza (Seasonal)
    • WHO1
  • 22
    • 0034055552 scopus 로고    scopus 로고
    • Epidemiology and virology of influenza illness
    • Monto, A.S. Epidemiology and virology of influenza illness. Am. J. Manag. Care 2000, 6, S255–S264.
    • (2000) Am. J. Manag. Care , vol.6 , pp. 255-264
    • Monto, A.S.1
  • 23
    • 79955554675 scopus 로고    scopus 로고
    • Global influenza seasonality: Reconciling patterns across temperate and tropical regions. Environ
    • Tamerius, J.; Nelson, M.I.; Zhou, S.Z.; Viboud, C.; Miller, M.A.; Alonso, W.J. Global influenza seasonality: Reconciling patterns across temperate and tropical regions. Environ. Health Perspect. 2011, 119, 439–445.
    • (2011) Health Perspect , vol.119 , pp. 439-445
    • Tamerius, J.1    Nelson, M.I.2    Zhou, S.Z.3    Viboud, C.4    Miller, M.A.5    Alonso, W.J.6
  • 24
    • 78649806995 scopus 로고    scopus 로고
    • Transmission of influenza virus in temperate zones is predominantly by aerosol, in the tropics by contact: A hypothesis
    • RRN1002
    • Lowen, A.; Palese, P. Transmission of influenza virus in temperate zones is predominantly by aerosol, in the tropics by contact: A hypothesis. PLoS Curr. 2009, 1, RRN1002.
    • (2009) Plos Curr , pp. 1
    • Lowen, A.1    Palese, P.2
  • 25
    • 43949134877 scopus 로고    scopus 로고
    • High temperature (30 degrees c) blocks aerosol but not contact transmission of influenza virus
    • Lowen, A.C.; Steel, J.; Mubareka, S.; Palese, P. High temperature (30 degrees c) blocks aerosol but not contact transmission of influenza virus. J. Virol. 2008, 82, 5650–5652.
    • (2008) J. Virol , vol.82 , pp. 5650-5652
    • Lowen, A.C.1    Steel, J.2    Mubareka, S.3    Palese, P.4
  • 26
    • 84871824506 scopus 로고    scopus 로고
    • Clinical use of approved influenza antivirals: Therapy and prophylaxis
    • Ison, M.G. Clinical use of approved influenza antivirals: Therapy and prophylaxis. Influ. Other Respir. Viruses 2013, 7, 7–13.
    • (2013) Influ. Other Respir. Viruses , vol.7 , pp. 7-13
    • Ison, M.G.1
  • 27
    • 84887921509 scopus 로고    scopus 로고
    • Influenza treatment and prophylaxis with neuraminidase inhibitors: A review
    • Kamali, A.; Holodniy, M. Influenza treatment and prophylaxis with neuraminidase inhibitors: A review. Infect. Drug Resist. 2013, 6, 187–198.
    • (2013) Infect. Drug Resist , vol.6 , pp. 187-198
    • Kamali, A.1    Holodniy, M.2
  • 29
    • 33751517736 scopus 로고    scopus 로고
    • Antiviral agents active against influenza a viruses
    • De Clercq, E. Antiviral agents active against influenza a viruses. Nat. Rev. Drug Discov. 2006, 5, 1015–1025.
    • (2006) Nat. Rev. Drug Discov , vol.5 , pp. 1015-1025
    • De Clercq, E.1
  • 30
    • 51449118699 scopus 로고    scopus 로고
    • Efficacy and effectiveness of influenza vaccination
    • Nichol, K.L. Efficacy and effectiveness of influenza vaccination. Vaccine 2008, 26, D17–D22.
    • (2008) Vaccine , vol.26 , pp. 17-22
    • Nichol, K.L.1
  • 31
    • 31344450870 scopus 로고    scopus 로고
    • Making better influenza virus vaccines?
    • Palese, P. Making better influenza virus vaccines? Emerg. Infect. Dis. 2006, 12, 61–65.
    • (2006) Emerg. Infect. Dis , vol.12 , pp. 61-65
    • Palese, P.1
  • 32
    • 84870044640 scopus 로고    scopus 로고
    • The coming era of quadrivalent human influenza vaccines: Who will benefit?
    • Barr, I.G.; Jelley, L.L. The coming era of quadrivalent human influenza vaccines: Who will benefit? Drugs 2012, 72, 2177–2185.
    • (2012) Drugs , vol.72 , pp. 2177-2185
    • Barr, I.G.1    Jelley, L.L.2
  • 33
    • 84861826001 scopus 로고    scopus 로고
    • The rationale for quadrivalent influenza vaccines
    • Ambrose, C.S.; Levin, M.J. The rationale for quadrivalent influenza vaccines. Hum. Vaccin. Immunother. 2012, 8, 81–88.
    • (2012) Hum. Vaccin. Immunother , vol.8 , pp. 81-88
    • Ambrose, C.S.1    Levin, M.J.2
  • 36
  • 39
    • 84873023493 scopus 로고    scopus 로고
    • Toward a universal influenza virus vaccine: Prospects and challenges
    • Pica, N.; Palese, P. Toward a universal influenza virus vaccine: Prospects and challenges. Annu. Rev. Med. 2013, 64, 189–202.
    • (2013) Annu. Rev. Med , vol.64 , pp. 189-202
    • Pica, N.1    Palese, P.2
  • 40
    • 84885953445 scopus 로고    scopus 로고
    • Influenza virus hemagglutinin stalk-based antibodies and vaccines
    • Krammer, F.; Palese, P. Influenza virus hemagglutinin stalk-based antibodies and vaccines. Current opinion in virology 2013, 3, 521–530.
    • (2013) Current Opinion in Virology , vol.3 , pp. 521-530
    • Krammer, F.1    Palese, P.2
  • 42
    • 85046186866 scopus 로고
    • The virus of influenza
    • The virus of influenza. Lancet 1933, 222, 83.
    • (1933) Lancet , vol.222 , pp. 83
  • 44
    • 79955140828 scopus 로고    scopus 로고
    • Pandemic H1N1 influenza virus causes a stronger inflammatory response than seasonal H1N1 influenza virus in ferrets
    • Kang, Y.M.; Song, B.M.; Lee, J.S.; Kim, H.S.; Seo, S.H. Pandemic H1N1 influenza virus causes a stronger inflammatory response than seasonal H1N1 influenza virus in ferrets. Arch. Virol. 2011, 156, 759–767.
    • (2011) Arch. Virol , vol.156 , pp. 759-767
    • Kang, Y.M.1    Song, B.M.2    Lee, J.S.3    Kim, H.S.4    Seo, S.H.5
  • 45
    • 81155128253 scopus 로고    scopus 로고
    • Comparative analyses of pandemic H1N1 and seasonal H1N1, H3N2, and influenza b infections depict distinct clinical pictures in ferrets
    • Huang, S.S.; Banner, D.; Fang, Y.; Ng, D.C.; Kanagasabai, T.; Kelvin, D.J.; Kelvin, A.A. Comparative analyses of pandemic H1N1 and seasonal H1N1, H3N2, and influenza b infections depict distinct clinical pictures in ferrets. PLoS One 2011, 6, e27512.
    • (2011) Plos One , vol.6 , pp. 27512
    • Huang, S.S.1    Banner, D.2    Fang, Y.3    Ng, D.C.4    Kanagasabai, T.5    Kelvin, D.J.6    Kelvin, A.A.7
  • 46
    • 82355190103 scopus 로고    scopus 로고
    • Virulence differences of closely related pandemic 2009 H1N1 isolates correlate with increased inflammatory responses in ferrets.
    • Meunier, I.; Embury-Hyatt, C.; Stebner, S.; Gray, M.; Bastien, N.; Li, Y.; Plummer, F.; Kobinger, G.P.; von Messling, V. Virulence differences of closely related pandemic 2009 H1N1 isolates correlate with increased inflammatory responses in ferrets. Virology 2012, 422, 125–131.
    • Virology , vol.2012 , Issue.422 , pp. 125-131
    • Meunier, I.1    Embury-Hyatt, C.2    Stebner, S.3    Gray, M.4    Bastien, N.5    Li, Y.6    Plummer, F.7    Kobinger, G.P.8    Von Messling, V.9
  • 47
    • 84864658161 scopus 로고    scopus 로고
    • Comparison of temporal and spatial dynamics of seasonal H3N2, pandemic H1N1 and highly pathogenic avian influenza H5N1 virus infections in ferrets
    • Van den Brand, J.M.; Stittelaar, K.J.; van Amerongen, G.; Reperant, L.; de Waal, L.; Osterhaus, A.D.; Kuiken, T. Comparison of temporal and spatial dynamics of seasonal H3N2, pandemic H1N1 and highly pathogenic avian influenza H5N1 virus infections in ferrets. PLoS One 2012, 7, e42343.
    • (2012) Plos One , vol.7 , pp. 42343
    • Van Den Brand, J.M.1    Stittelaar, K.J.2    Van Amerongen, G.3    Reperant, L.4    De Waal, L.5    Osterhaus, A.D.6    Kuiken, T.7
  • 49
    • 77954501872 scopus 로고    scopus 로고
    • Evaluation of replication and cross-reactive antibody responses of h2 subtype influenza viruses in mice and ferrets
    • Chen, G.L.; Lamirande, E.W.; Yang, C.F.; Jin, H.; Kemble, G.; Subbarao, K. Evaluation of replication and cross-reactive antibody responses of h2 subtype influenza viruses in mice and ferrets. J. Virol. 2010, 84, 7695–7702.
    • (2010) J. Virol , vol.84 , pp. 7695-7702
    • Chen, G.L.1    Lamirande, E.W.2    Yang, C.F.3    Jin, H.4    Kemble, G.5    Subbarao, K.6
  • 52
    • 84885123699 scopus 로고    scopus 로고
    • Evaluation of live attenuated H7N3 and H7N7 vaccine viruses for their receptor binding preferences, immunogenicity in ferrets and cross reactivity to the novel H7N9 virus
    • Xu, Q.; Chen, Z.; Cheng, X.; Xu, L.; Jin, H. Evaluation of live attenuated H7N3 and H7N7 vaccine viruses for their receptor binding preferences, immunogenicity in ferrets and cross reactivity to the novel H7N9 virus. PLoS One 2013, 8, e76884.
    • (2013) Plos One , vol.8 , pp. 76884
    • Xu, Q.1    Chen, Z.2    Cheng, X.3    Xu, L.4    Jin, H.5
  • 53
    • 79961092156 scopus 로고    scopus 로고
    • Compatibility of H9N2 avian influenza surface genes and 2009 pandemic H1N1 internal genes for transmission in the ferret model
    • Kimble, J.B.; Sorrell, E.; Shao, H.; Martin, P.L.; Perez, D.R. Compatibility of H9N2 avian influenza surface genes and 2009 pandemic H1N1 internal genes for transmission in the ferret model. Proc. Natl. Acad. Sci. USA 2011, 108, 12084–12088.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 12084-12088
    • Kimble, J.B.1    Sorrell, E.2    Shao, H.3    Martin, P.L.4    Perez, D.R.5
  • 56
    • 35348888890 scopus 로고    scopus 로고
    • Human and avian influenza viruses target different cells in the lower respiratory tract of humans and other mammals
    • Van Riel, D.; Munster, V.J.; de Wit, E.; Rimmelzwaan, G.F.; Fouchier, R.A.; Osterhaus, A.D.; Kuiken, T. Human and avian influenza viruses target different cells in the lower respiratory tract of humans and other mammals. Am. J. Pathol. 2007, 171, 1215–1223.
    • (2007) Am. J. Pathol , vol.171 , pp. 1215-1223
    • Van Riel, D.1    Munster, V.J.2    De Wit, E.3    Rimmelzwaan, G.F.4    Fouchier, R.A.5    Osterhaus, A.D.6    Kuiken, T.7
  • 58
    • 84870681226 scopus 로고    scopus 로고
    • Differential pathological and immune responses in newly weaned ferrets are associated with a mild clinical outcome of pandemic 2009 H1N1 infection
    • Huang, S.S.; Banner, D.; Degousee, N.; Leon, A.J.; Xu, L.; Paquette, S.G.; Kanagasabai, T.; Fang, Y.; Rubino, S.; Rubin, B. et al. Differential pathological and immune responses in newly weaned ferrets are associated with a mild clinical outcome of pandemic 2009 H1N1 infection. J. Virol. 2012, 86, 13187–13201.
    • (2012) J. Virol , vol.86 , pp. 13187-13201
    • Huang, S.S.1    Banner, D.2    Degousee, N.3    Leon, A.J.4    Xu, L.5    Paquette, S.G.6    Kanagasabai, T.7    Fang, Y.8    Rubino, S.9    Rubin, B.10
  • 59
    • 80051771826 scopus 로고    scopus 로고
    • Pathogenesis of influenza a/H5N1 virus infection in ferrets differs between intranasal and intratracheal routes of inoculation
    • Bodewes, R.; Kreijtz, J.H.; van Amerongen, G.; Fouchier, R.A.; Osterhaus, A.D.; Rimmelzwaan, G.F.; Kuiken, T. Pathogenesis of influenza a/H5N1 virus infection in ferrets differs between intranasal and intratracheal routes of inoculation. Am. J. Pathol. 2011, 179, 30–36.
    • (2011) Am. J. Pathol. , vol.179 , pp. 30-36
    • Bodewes, R.1    Kreijtz, J.H.2    Van Amerongen, G.3    Fouchier, R.A.4    Osterhaus, A.D.5    Rimmelzwaan, G.F.6    Kuiken, T.7
  • 60
    • 74349124127 scopus 로고    scopus 로고
    • Animal models for the preclinical evaluation of candidate influenza vaccines
    • Bodewes, R.; Rimmelzwaan, G.F.; Osterhaus, A.D. Animal models for the preclinical evaluation of candidate influenza vaccines. Expert Rev. Vaccines 2010, 9, 59–72.
    • (2010) Expert Rev. Vaccines , vol.9 , pp. 59-72
    • Bodewes, R.1    Rimmelzwaan, G.F.2    Osterhaus, A.D.3
  • 61
    • 0036223619 scopus 로고    scopus 로고
    • Pathogenesis of avian influenza a (H5N1) viruses in ferrets
    • Zitzow, L.A.; Rowe, T.; Morken, T.; Shieh, W.J.; Zaki, S.; Katz, J.M. Pathogenesis of avian influenza a (H5N1) viruses in ferrets. J. Virol. 2002, 76, 4420–4429.
    • (2002) J. Virol , vol.76 , pp. 4420-4429
    • Zitzow, L.A.1    Rowe, T.2    Morken, T.3    Shieh, W.J.4    Zaki, S.5    Katz, J.M.6
  • 63
    • 6944227719 scopus 로고    scopus 로고
    • Influenza viruses resistant to the antiviral drug oseltamivir: Transmission studies in ferrets
    • Herlocher, M.L.; Truscon, R.; Elias, S.; Yen, H.L.; Roberts, N.A.; Ohmit, S.E.; Monto, A.S. Influenza viruses resistant to the antiviral drug oseltamivir: Transmission studies in ferrets. J. Infect. Dis. 2004, 190, 1627–1630.
    • (2004) J. Infect. Dis , vol.190 , pp. 1627-1630
    • Herlocher, M.L.1    Truscon, R.2    Elias, S.3    Yen, H.L.4    Roberts, N.A.5    Ohmit, S.E.6    Monto, A.S.7
  • 65
    • 0023791475 scopus 로고
    • Influenza virus-susceptible mice carry mx genes with a large deletion or a nonsense mutation
    • Staeheli, P.; Grob, R.; Meier, E.; Sutcliffe, J.G.; Haller, O. Influenza virus-susceptible mice carry mx genes with a large deletion or a nonsense mutation. Mol. Cell. Biol. 1988, 8, 4518–4523.
    • (1988) Mol. Cell. Biol , vol.8 , pp. 4518-4523
    • Staeheli, P.1    Grob, R.2    Meier, E.3    Sutcliffe, J.G.4    Haller, O.5
  • 67
    • 58349121196 scopus 로고    scopus 로고
    • Adaptation of human influenza H3N2 virus in a mouse pneumonitis model: Insights into viral virulence, tissue tropism and host pathogenesis
    • Narasaraju, T.; Sim, M.K.; Ng, H.H.; Phoon, M.C.; Shanker, N.; Lal, S.K.; Chow, V.T. Adaptation of human influenza H3N2 virus in a mouse pneumonitis model: Insights into viral virulence, tissue tropism and host pathogenesis. Microbes Infect./Inst. Pasteur 2009, 11, 2–11.
    • (2009) Microbes Infect./Inst. Pasteur , vol.11 , pp. 2-11
    • Narasaraju, T.1    Sim, M.K.2    Ng, H.H.3    Phoon, M.C.4    Shanker, N.5    Lal, S.K.6    Chow, V.T.7
  • 68
    • 79956295593 scopus 로고    scopus 로고
    • Mutations in pa, np, and ha of a pandemic (H1N1) 2009 influenza virus contribute to its adaptation to mice
    • Sakabe, S.; Ozawa, M.; Takano, R.; Iwastuki-Horimoto, K.; Kawaoka, Y. Mutations in pa, np, and ha of a pandemic (H1N1) 2009 influenza virus contribute to its adaptation to mice. Virus Res. 2011, 158, 124–129.
    • (2011) Virus Res , vol.158 , pp. 124-129
    • Sakabe, S.1    Ozawa, M.2    Takano, R.3    Iwastuki-Horimoto, K.4    Kawaoka, Y.5
  • 69
    • 84907874656 scopus 로고    scopus 로고
    • Nonpathogenic duck-origin H9N2 influenza a virus adapts to high pathogenicity in mice
    • Liu, Q.; Chen, H.; Huang, J.; Chen, Y.; Gu, M.; Wang, X.; Hu, S.; Liu, X.; Liu, X. A nonpathogenic duck-origin H9N2 influenza a virus adapts to high pathogenicity in mice. Arch. Virol. 2014, doi:10.1007/s00705-014-2062-y.
    • (2014) Arch. Virol
    • Liu, Q.1    Chen, H.2    Huang, J.3    Chen, Y.4    Gu, M.5    Wang, X.6    Hu, S.7    Liu, X.8    Liu, X.A.9
  • 71
    • 0033014710 scopus 로고    scopus 로고
    • Biological heterogeneity, including systemic replication in mice, of H5N1 influenza a virus isolates from humans in hong kong
    • Gao, P.; Watanabe, S.; Ito, T.; Goto, H.; Wells, K.; McGregor, M.; Cooley, A.J.; Kawaoka, Y. Biological heterogeneity, including systemic replication in mice, of H5N1 influenza a virus isolates from humans in hong kong. J. Virol. 1999, 73, 3184–3189.
    • (1999) J. Virol , vol.73 , pp. 3184-3189
    • Gao, P.1    Watanabe, S.2    Ito, T.3    Goto, H.4    Wells, K.5    McGregor, M.6    Cooley, A.J.7    Kawaoka, Y.8
  • 72
    • 0033064858 scopus 로고    scopus 로고
    • Katz, J.M. A mouse model for the evaluation of pathogenesis and immunity to influenza a (H5N1) viruses isolated from humans
    • Lu, X.; Tumpey, T.M.; Morken, T.; Zaki, S.R.; Cox, N.J.; Katz, J.M. A mouse model for the evaluation of pathogenesis and immunity to influenza a (H5N1) viruses isolated from humans. J. Virol. 1999, 73, 5903–5911.
    • (1999) J. Virol , vol.73 , pp. 5903-5911
    • Lu, X.1    Tumpey, T.M.2    Morken, T.3    Zaki, S.R.4    Cox, N.J.5
  • 73
    • 84881134728 scopus 로고    scopus 로고
    • The mouse and ferret models for studying the novel avian-origin human influenza a (H7N9) virus
    • Xu, L.; Bao, L.; Deng, W.; Zhu, H.; Chen, T.; Lv, Q.; Li, F.; Yuan, J.; Xiang, Z.; Gao, K. et al. The mouse and ferret models for studying the novel avian-origin human influenza a (H7N9) virus. Virol. J. 2013, 10, 253.
    • (2013) Virol. J , vol.10 , pp. 253
    • Xu, L.1    Bao, L.2    Deng, W.3    Zhu, H.4    Chen, T.5    Lv, Q.6    Li, F.7    Yuan, J.8    Xiang, Z.9    Gao, K.10
  • 77
    • 6944227719 scopus 로고    scopus 로고
    • Influenza viruses resistant to the antiviral drug oseltamivir: Transmission studies in ferrets
    • Herlocher, M.L.; Truscon, R.; Elias, S.; Yen, H.L.; Roberts, N.A.; Ohmit, S.E.; Monto, A.S. Influenza viruses resistant to the antiviral drug oseltamivir: Transmission studies in ferrets. J. Infect. Dis. 2004, 190, 1627–1630.
    • (2004) J. Infect. Dis , vol.190 , pp. 1627-1630
    • Herlocher, M.L.1    Truscon, R.2    Elias, S.3    Yen, H.L.4    Roberts, N.A.5    Ohmit, S.E.6    Monto, A.S.7
  • 79
    • 0023791475 scopus 로고
    • Influenza virus-susceptible mice carry mx genes with a large deletion or a nonsense mutation
    • Staeheli, P.; Grob, R.; Meier, E.; Sutcliffe, J.G.; Haller, O. Influenza virus-susceptible mice carry mx genes with a large deletion or a nonsense mutation. Mol. Cell. Biol. 1988, 8, 4518–4523.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 4518-4523
    • Staeheli, P.1    Grob, R.2    Meier, E.3    Sutcliffe, J.G.4    Haller, O.5
  • 81
    • 58349121196 scopus 로고    scopus 로고
    • Adaptation of human influenza H3N2 virus in a mouse pneumonitis model: Insights into viral virulence, tissue tropism and host pathogenesis
    • Narasaraju, T.; Sim, M.K.; Ng, H.H.; Phoon, M.C.; Shanker, N.; Lal, S.K.; Chow, V.T. Adaptation of human influenza H3N2 virus in a mouse pneumonitis model: Insights into viral virulence, tissue tropism and host pathogenesis. Microbes Infect./Inst. Pasteur 2009, 11, 2–11.
    • (2009) Microbes Infect./Inst. Pasteur , vol.11 , pp. 2-11
    • Narasaraju, T.1    Sim, M.K.2    Ng, H.H.3    Phoon, M.C.4    Shanker, N.5    Lal, S.K.6    Chow, V.T.7
  • 82
    • 79956295593 scopus 로고    scopus 로고
    • Mutations in pa, np, and ha of a pandemic (H1N1) 2009 influenza virus contribute to its adaptation to mice
    • Sakabe, S.; Ozawa, M.; Takano, R.; Iwastuki-Horimoto, K.; Kawaoka, Y. Mutations in pa, np, and ha of a pandemic (H1N1) 2009 influenza virus contribute to its adaptation to mice. Virus Res. 2011, 158, 124–129.
    • (2011) Virus Res , vol.158 , pp. 124-129
    • Sakabe, S.1    Ozawa, M.2    Takano, R.3    Iwastuki-Horimoto, K.4    Kawaoka, Y.5
  • 83
    • 84907874656 scopus 로고    scopus 로고
    • Nonpathogenic duck-origin H9N2 influenza a virus adapts to high pathogenicity in mice
    • Liu, Q.; Chen, H.; Huang, J.; Chen, Y.; Gu, M.; Wang, X.; Hu, S.; Liu, X.; Liu, X. A nonpathogenic duck-origin H9N2 influenza a virus adapts to high pathogenicity in mice. Arch. Virol. 2014, doi:10.1007/s00705-014-2062-y.
    • (2014) Arch. Virol
    • Liu, Q.1    Chen, H.2    Huang, J.3    Chen, Y.4    Gu, M.5    Wang, X.6    Hu, S.7    Liu, X.8    Liu, X.A.9
  • 85
    • 0033014710 scopus 로고    scopus 로고
    • Biological heterogeneity, including systemic replication in mice, of H5N1 influenza a virus isolates from humans in hong kong
    • Gao, P.; Watanabe, S.; Ito, T.; Goto, H.; Wells, K.; McGregor, M.; Cooley, A.J.; Kawaoka, Y. Biological heterogeneity, including systemic replication in mice, of H5N1 influenza a virus isolates from humans in hong kong. J. Virol. 1999, 73, 3184–3189.
    • (1999) J. Virol , vol.73 , pp. 3184-3189
    • Gao, P.1    Watanabe, S.2    Ito, T.3    Goto, H.4    Wells, K.5    McGregor, M.6    Cooley, A.J.7    Kawaoka, Y.8
  • 86
    • 0033064858 scopus 로고    scopus 로고
    • Katz, J.M. A mouse model for the evaluation of pathogenesis and immunity to influenza a (H5N1) viruses isolated from humans
    • Lu, X.; Tumpey, T.M.; Morken, T.; Zaki, S.R.; Cox, N.J.; Katz, J.M. A mouse model for the evaluation of pathogenesis and immunity to influenza a (H5N1) viruses isolated from humans. J. Virol. 1999, 73, 5903–5911.
    • (1999) J. Virol , vol.73 , pp. 5903-5911
    • Lu, X.1    Tumpey, T.M.2    Morken, T.3    Zaki, S.R.4    Cox, N.J.5
  • 87
    • 84881134728 scopus 로고    scopus 로고
    • The mouse and ferret models for studying the novel avian-origin human influenza a (H7N9) virus
    • Xu, L.; Bao, L.; Deng, W.; Zhu, H.; Chen, T.; Lv, Q.; Li, F.; Yuan, J.; Xiang, Z.; Gao, K. et al. The mouse and ferret models for studying the novel avian-origin human influenza a (H7N9) virus. Virol. J. 2013, 10, 253.
    • (2013) Virol. J , vol.10 , pp. 253
    • Xu, L.1    Bao, L.2    Deng, W.3    Zhu, H.4    Chen, T.5    Lv, Q.6    Li, F.7    Yuan, J.8    Xiang, Z.9    Gao, K.10
  • 90
    • 84893797938 scopus 로고    scopus 로고
    • Broadly neutralizing hemagglutinin stalk-specific antibodies require fcgammar interactions for protection against influenza virus in vivo
    • DiLillo, D.J.; Tan, G.S.; Palese, P.; Ravetch, J.V. Broadly neutralizing hemagglutinin stalk-specific antibodies require fcgammar interactions for protection against influenza virus in vivo. Nat. Med. 2014, 20, 143–151.
    • (2014) Nat. Med , vol.20 , pp. 143-151
    • Dilillo, D.J.1    Tan, G.S.2    Palese, P.3    Ravetch, J.V.4
  • 94
    • 67349202767 scopus 로고    scopus 로고
    • Animal models for the study of influenza pathogenesis and therapy
    • Barnard, D.L. Animal models for the study of influenza pathogenesis and therapy. Antivir. Res. 2009, 82, A110–A122.
    • (2009) Antivir. Res , vol.82 , pp. 110-112
    • Barnard, D.L.1
  • 99
    • 42149137395 scopus 로고    scopus 로고
    • Interferon-induced expression of mxa in the respiratory tract of rhesus macaques is suppressed by influenza virus replication
    • Carroll, T.D.; Matzinger, S.R.; Genesca, M.; Fritts, L.; Colon, R.; McChesney, M.B.; Miller, C.J. Interferon-induced expression of mxa in the respiratory tract of rhesus macaques is suppressed by influenza virus replication. J. Immunol. 2008, 180, 2385–2395.
    • (2008) J. Immunol , vol.180 , pp. 2385-2395
    • Carroll, T.D.1    Matzinger, S.R.2    Genesca, M.3    Fritts, L.4    Colon, R.5    McChesney, M.B.6    Miller, C.J.7
  • 100
    • 0035850965 scopus 로고    scopus 로고
    • A single dose of an iscom influenza vaccine induces long-lasting protective immunity against homologous challenge infection but fails to protect cynomolgus macaques against distant drift variants of influenza a (H3N2) viruses
    • Rimmelzwaan, G.F.; Baars, M.; van Amerongen, G.; van Beek, R.; Osterhaus, A.D. A single dose of an iscom influenza vaccine induces long-lasting protective immunity against homologous challenge infection but fails to protect cynomolgus macaques against distant drift variants of influenza a (H3N2) viruses. Vaccine 2001, 20, 158–163.
    • (2001) Vaccine , vol.20 , pp. 158-163
    • Rimmelzwaan, G.F.1    Baars, M.2    Van Amerongen, G.3    Van Beek, R.4    Osterhaus, A.D.5
  • 107
    • 36049022594 scopus 로고    scopus 로고
    • Influenza virus transmission is dependent on relative humidity and temperature
    • Lowen, A.C.; Mubareka, S.; Steel, J.; Palese, P. Influenza virus transmission is dependent on relative humidity and temperature. PLoS Pathog. 2007, 3, 1470–1476.
    • (2007) Plos Pathog , vol.3 , pp. 1470-1476
    • Lowen, A.C.1    Mubareka, S.2    Steel, J.3    Palese, P.4
  • 109
    • 84861371388 scopus 로고    scopus 로고
    • Transmission of influenza b viruses in the guinea pig
    • Pica, N.; Chou, Y.Y.; Bouvier, N.M.; Palese, P. Transmission of influenza b viruses in the guinea pig. J. Virol. 2012, 86, 4279–4287.
    • (2012) J. Virol , vol.86 , pp. 4279-4287
    • Pica, N.1    Chou, Y.Y.2    Bouvier, N.M.3    Palese, P.4
  • 110
    • 63149094651 scopus 로고    scopus 로고
    • Blocking interhost transmission of influenza virus by vaccination in the guinea pig model
    • Lowen, A.C.; Steel, J.; Mubareka, S.; Carnero, E.; García-Sastre, A.; Palese, P. Blocking interhost transmission of influenza virus by vaccination in the guinea pig model. J. Virol. 2009, 83, 2803–2818.
    • (2009) J. Virol , vol.83 , pp. 2803-2818
    • Lowen, A.C.1    Steel, J.2    Mubareka, S.3    Carnero, E.4    García-Sastre, A.5    Palese, P.6
  • 112
    • 0642344592 scopus 로고    scopus 로고
    • Comparison of hamster and pony challenge models for evaluation of effect of antigenic drift on cross protection afforded by equine influenza vaccines
    • Daly, J.M.; Yates, R.J.; Browse, G.; Swann, Z.; Newton, J.R.; Jessett, D.; Davis-Poynter, N.; Mumford, J.A. Comparison of hamster and pony challenge models for evaluation of effect of antigenic drift on cross protection afforded by equine influenza vaccines. Equine Vet. J. 2003, 35, 458–462.
    • (2003) Equine Vet. J. , vol.35 , pp. 458-462
    • Daly, J.M.1    Yates, R.J.2    Browse, G.3    Swann, Z.4    Newton, J.R.5    Jessett, D.6    Davis-Poynter, N.7    Mumford, J.A.8
  • 113
    • 0019311498 scopus 로고
    • Growth of influenza a viruses in hamsters
    • Abou-Donia, H.; Jennings, R.; Potter, C.W. Growth of influenza a viruses in hamsters. Arch. Virol. 1980, 65, 99–107.
    • (1980) Arch. Virol , vol.65 , pp. 99-107
    • Abou-Donia, H.1    Jennings, R.2    Potter, C.W.3
  • 114
    • 0017865075 scopus 로고
    • The hamster as a model for the study of immunity to influenza virus infection
    • Jennings, R.; Potter, C.W. The hamster as a model for the study of immunity to influenza virus infection. Fed. Proc. 1978, 37, 2072–2073.
    • (1978) Fed. Proc , vol.37 , pp. 2072-2073
    • Jennings, R.1    Potter, C.W.2
  • 115
    • 0017140405 scopus 로고
    • The hamster as a model system for the study of influenza vaccines
    • Potter, C.W.; Jennings, R. The hamster as a model system for the study of influenza vaccines. Postgrad. Med. J. 1976, 52, 345–351.
    • (1976) Postgrad. Med. J , vol.52 , pp. 345-351
    • Potter, C.W.1    Jennings, R.2
  • 116
    • 0017201816 scopus 로고
    • The hamster as an experimental animal for the study of influenza. I. The role of antibody in protection
    • Jennings, R.; Denton, M.D.; Potter, C.W. The hamster as an experimental animal for the study of influenza. I. The role of antibody in protection. Med. Microbiol. Immunol. 1976, 162, 217–226.
    • (1976) Med. Microbiol. Immunol , vol.162 , pp. 217-226
    • Jennings, R.1    Denton, M.D.2    Potter, C.W.3
  • 117
    • 0017189613 scopus 로고
    • The hamster as an experimental animal for the study of influenza. Ii. The role of spleen cells in protection
    • Jennings, R.; Phair, J.P.; Denton, M.D.; Potter, C.W. The hamster as an experimental animal for the study of influenza. Ii. The role of spleen cells in protection. Med. Microbiol. Immunol. 1976, 162, 227–237.
    • (1976) Med. Microbiol. Immunol , vol.162 , pp. 227-237
    • Jennings, R.1    Phair, J.P.2    Denton, M.D.3    Potter, C.W.4
  • 118
    • 79955383487 scopus 로고    scopus 로고
    • Systemic dissemination of H5N1 influenza a viruses in ferrets and hamsters after direct intragastric inoculation
    • Shinya, K.; Makino, A.; Tanaka, H.; Hatta, M.; Watanabe, T.; Le, M.Q.; Imai, H.; Kawaoka, Y. Systemic dissemination of H5N1 influenza a viruses in ferrets and hamsters after direct intragastric inoculation. J. Virol. 2011, 85, 4673–4678.
    • (2011) J. Virol , vol.85 , pp. 4673-4678
    • Shinya, K.1    Makino, A.2    Tanaka, H.3    Hatta, M.4    Watanabe, T.5    Le, M.Q.6    Imai, H.7    Kawaoka, Y.8
  • 119
    • 0020320134 scopus 로고
    • Transmissibility of influenza viruses in hamsters
    • Ali, M.J.; Teh, C.Z.; Jennings, R.; Potter, C.W. Transmissibility of influenza viruses in hamsters. Arch. Virol. 1982, 72, 187–197.
    • (1982) Arch. Virol , vol.72 , pp. 187-197
    • Ali, M.J.1    Teh, C.Z.2    Jennings, R.3    Potter, C.W.4
  • 120
    • 34447515667 scopus 로고    scopus 로고
    • The cotton rat as a model to study influenza pathogenesis and immunity
    • Eichelberger, M.C. The cotton rat as a model to study influenza pathogenesis and immunity. Viral. Immunol. 2007, 20, 243–249.
    • (2007) Viral. Immunol , vol.20 , pp. 243-249
    • Eichelberger, M.C.1
  • 121
    • 67349246810 scopus 로고    scopus 로고
    • The cotton rat model of respiratory viral infections
    • Boukhvalova, M.S.; Prince, G.A.; Blanco, J.C. The cotton rat model of respiratory viral infections. Biologicals 2009, 37, 152–159.
    • (2009) Biologicals , vol.37 , pp. 152-159
    • Boukhvalova, M.S.1    Prince, G.A.2    Blanco, J.C.3
  • 122
    • 84856581620 scopus 로고    scopus 로고
    • Efficacy of trivalent inactivated influenza vaccines in the cotton rat sigmodon hispidus model
    • Yim, K.; Miles, B.; Zinsou, R.; Prince, G.; Boukhvalova, M. Efficacy of trivalent inactivated influenza vaccines in the cotton rat sigmodon hispidus model. Vaccine 2012, 30, 1291–1296.
    • (2012) Vaccine , vol.30 , pp. 1291-1296
    • Yim, K.1    Miles, B.2    Zinsou, R.3    Prince, G.4    Boukhvalova, M.5
  • 123
    • 33747364252 scopus 로고    scopus 로고
    • Evidence of a cross-protective immune response to influenza a in the cotton rat model
    • Straight, T.M.; Ottolini, M.G.; Prince, G.A.; Eichelberger, M.C. Evidence of a cross-protective immune response to influenza a in the cotton rat model. Vaccine 2006, 24, 6264–6271.
    • (2006) Vaccine , vol.24 , pp. 6264-6271
    • Straight, T.M.1    Ottolini, M.G.2    Prince, G.A.3    Eichelberger, M.C.4
  • 124
    • 84873867721 scopus 로고    scopus 로고
    • Receptor characterization and susceptibility of cotton rats to avian and 2009 pandemic influenza virus strains
    • Blanco, J.C.; Pletneva, L.M.; Wan, H.; Araya, Y.; Angel, M.; Oue, R.O.; Sutton, T.C.; Perez, D.R. Receptor characterization and susceptibility of cotton rats to avian and 2009 pandemic influenza virus strains. J. Virol. 2013, 87, 2036–2045.
    • (2013) J. Virol , vol.87 , pp. 2036-2045
    • Blanco, J.C.1    Pletneva, L.M.2    Wan, H.3    Araya, Y.4    Angel, M.5    Oue, R.O.6    Sutton, T.C.7    Perez, D.R.8
  • 125
    • 0141677652 scopus 로고    scopus 로고
    • Recombinant paramyxovirus type 1-avian influenza-h7 virus as a vaccine for protection of chickens against influenza and newcastle disease
    • Swayne, D.E.; Suarez, D.L.; Schultz-Cherry, S.; Tumpey, T.M.; King, D.J.; Nakaya, T.; Palese, P.; Garcia-Sastre, A. Recombinant paramyxovirus type 1-avian influenza-h7 virus as a vaccine for protection of chickens against influenza and newcastle disease. Avian Dis. 2003, 47, 1047–1050.
    • (2003) Avian Dis , vol.47 , pp. 1047-1050
    • Swayne, D.E.1    Suarez, D.L.2    Schultz-Cherry, S.3    Tumpey, T.M.4    King, D.J.5    Nakaya, T.6    Palese, P.7    Garcia-Sastre, A.8
  • 126
    • 77956291661 scopus 로고    scopus 로고
    • A single immunization with soluble recombinant trimeric hemagglutinin protects chickens against highly pathogenic avian influenza virus H5N1
    • Cornelissen, L.A.; de Vries, R.P.; de Boer-Luijtze, E.A.; Rigter, A.; Rottier, P.J.; de Haan, C.A. A single immunization with soluble recombinant trimeric hemagglutinin protects chickens against highly pathogenic avian influenza virus H5N1. PLoS One 2010, 5, e10645.
    • (2010) Plos One , vol.5 , pp. 10645
    • Cornelissen, L.A.1    De Vries, R.P.2    De Boer-Luijtze, E.A.3    Rigter, A.4    Rottier, P.J.5    De Haan, C.A.6
  • 127
    • 0034163283 scopus 로고    scopus 로고
    • Immunology of avian influenza virus: A review.
    • Suarez, D.L.; Schultz-Cherry, S. Immunology of avian influenza virus: A review. Dev. Comp. Immunol. 2000, 24, 269–283.
    • (2000) Dev. Comp. Immunol , vol.24 , pp. 269-283
    • Suarez, D.L.1    Schultz-Cherry, S.2
  • 128
    • 84887622159 scopus 로고    scopus 로고
    • Vaccination of domestic ducks against H5N1 hpai: A review
    • Pantin-Jackwood, M.J.; Suarez, D.L. Vaccination of domestic ducks against H5N1 hpai: A review. Virus Res. 2013, 178, 21–34.
    • (2013) Virus Res. , vol.178 , pp. 21-34
    • Pantin-Jackwood, M.J.1    Suarez, D.L.2
  • 130
    • 33646126915 scopus 로고    scopus 로고
    • Vaccination against equine influenza: Quid novi?
    • Paillot, R.; Hannant, D.; Kydd, J.H.; Daly, J.M. Vaccination against equine influenza: Quid novi? Vaccine 2006, 24, 4047–4061.
    • (2006) Vaccine , vol.24 , pp. 4047-4061
    • Paillot, R.1    Hannant, D.2    Kydd, J.H.3    Daly, J.M.4
  • 133
    • 80051906313 scopus 로고    scopus 로고
    • Animal models to assess the toxicity, immunogenicity and effectiveness of candidate influenza vaccines
    • Eichelberger, M.C.; Green, M.D. Animal models to assess the toxicity, immunogenicity and effectiveness of candidate influenza vaccines. Expert Opin. Drug Metab. Toxicol. 2011, 7, 1117–1127.
    • (2011) Expert Opin. Drug Metab. Toxicol. , vol.7 , pp. 1117-1127
    • Eichelberger, M.C.1    Green, M.D.2
  • 134
    • 84908511240 scopus 로고    scopus 로고
    • Animal models for influenza virus pathogenesis, transmission, and immunology
    • Thangavel, R.R.; Bouvier, N.M. Animal models for influenza virus pathogenesis, transmission, and immunology. J. Immunol. Methods 2014, doi:10.1016/j.jim.2014.03.023.
    • (2014) J. Immunol. Methods
    • Thangavel, R.R.1    Bouvier, N.M.2
  • 135
    • 8144229816 scopus 로고    scopus 로고
    • Innate immune response in th1- and th2-dominant mouse strains
    • Watanabe, H.; Numata, K.; Ito, T.; Takagi, K.; Matsukawa, A. Innate immune response in th1- and th2-dominant mouse strains. Shock 2004, 22, 460–466.
    • (2004) Shock , vol.22 , pp. 460-466
    • Watanabe, H.1    Numata, K.2    Ito, T.3    Takagi, K.4    Matsukawa, A.5
  • 136
    • 81255179897 scopus 로고    scopus 로고
    • The dba.2 mouse is susceptible to disease following infection with a broad, but limited, range of influenza a and b viruses
    • Pica, N.; Iyer, A.; Ramos, I.; Bouvier, N.M.; Fernandez-Sesma, A.; Garcia-Sastre, A.; Lowen, A.C.; Palese, P.; Steel, J. The dba.2 mouse is susceptible to disease following infection with a broad, but limited, range of influenza a and b viruses. J. Virol. 2011, 85, 12825–12829.
    • (2011) J. Virol , vol.85 , pp. 12825-12829
    • Pica, N.1    Iyer, A.2    Ramos, I.3    Bouvier, N.M.4    Fernandez-Sesma, A.5    Garcia-Sastre, A.6    Lowen, A.C.7    Palese, P.8    Steel, J.9
  • 137
    • 0027471177 scopus 로고
    • Ueda, S. A common neutralizing epitope conserved between the hemagglutinins of influenza a virus h1 and h2 strains
    • Okuno, Y.; Isegawa, Y.; Sasao, F.; Ueda, S. A common neutralizing epitope conserved between the hemagglutinins of influenza a virus h1 and h2 strains. J. Virol. 1993, 67, 2552–2558.
    • (1993) J. Virol , vol.67 , pp. 2552-2558
    • Okuno, Y.1    Isegawa, Y.2    Sasao, F.3
  • 138
    • 84863597077 scopus 로고    scopus 로고
    • Pan-h1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo
    • Tan, G.S.; Krammer, F.; Eggink, D.; Kongchanagul, A.; Moran, T.M.; Palese, P. A pan-h1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo. J. Virol. 2012, 86, 6179–6188.
    • (2012) J. Virol , vol.86 , pp. 6179-6188
    • Tan, G.S.1    Krammer, F.2    Eggink, D.3    Kongchanagul, A.4    Moran, T.M.5    Palese, P.A.6
  • 139
    • 77649242815 scopus 로고    scopus 로고
    • Broadly protective monoclonal antibodies against h3 influenza viruses following sequential immunization with different hemagglutinins
    • Wang, T.T.; Tan, G.S.; Hai, R.; Pica, N.; Petersen, E.; Moran, T.M.; Palese, P. Broadly protective monoclonal antibodies against h3 influenza viruses following sequential immunization with different hemagglutinins. PLoS Pathog. 2010, 6, e1000796.
    • (2010) Plos Pathog , vol.6 , pp. 1000796
    • Wang, T.T.1    Tan, G.S.2    Hai, R.3    Pica, N.4    Petersen, E.5    Moran, T.M.6    Palese, P.7
  • 141
    • 84863115945 scopus 로고    scopus 로고
    • Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses
    • Pica, N.; Hai, R.; Krammer, F.; Wang, T.T.; Maamary, J.; Eggink, D.; Tan, G.S.; Krause, J.C.; Moran, T.; Stein, C.R. et al. Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses. Proc. Natl. Acad. Sci. USA 2012, 109, 2573–2578.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 2573-2578
    • Pica, N.1    Hai, R.2    Krammer, F.3    Wang, T.T.4    Maamary, J.5    Eggink, D.6    Tan, G.S.7    Krause, J.C.8    Moran, T.9    Stein, C.R.10
  • 142
    • 84869059071 scopus 로고    scopus 로고
    • Hemagglutinin stalk-reactive antibodies are boosted following sequential infection with seasonal and pandemic H1N1 influenza virus in mice
    • Krammer, F.; Pica, N.; Hai, R.; Tan, G.S.; Palese, P. Hemagglutinin stalk-reactive antibodies are boosted following sequential infection with seasonal and pandemic H1N1 influenza virus in mice. J. Virol. 2012, 86, 10302–10307.
    • (2012) J. Virol , vol.86 , pp. 10302-10307
    • Krammer, F.1    Pica, N.2    Hai, R.3    Tan, G.S.4    Palese, P.5
  • 148
    • 84893496184 scopus 로고    scopus 로고
    • H3 stalk-based chimeric hemagglutinin influenza virus constructs protect mice from H7N9 challenge
    • Krammer, F.; Margine, I.; Hai, R.; Flood, A.; Hirsh, A.; Tsvetnitsky, V.; Chen, D.; Palese, P. H3 stalk-based chimeric hemagglutinin influenza virus constructs protect mice from H7N9 challenge. J. Virol. 2014, 88, 2340–2343.
    • (2014) J. Virol , vol.88 , pp. 2340-2343
    • Krammer, F.1    Margine, I.2    Hai, R.3    Flood, A.4    Hirsh, A.5    Tsvetnitsky, V.6    Chen, D.7    Palese, P.8
  • 149
    • 84878611784 scopus 로고    scopus 로고
    • Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalk-specific antibodies
    • Krammer, F.; Pica, N.; Hai, R.; Margine, I.; Palese, P. Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalk-specific antibodies. J. Virol. 2013, 87, 6542–6550.
    • (2013) J. Virol , vol.87 , pp. 6542-6550
    • Krammer, F.1    Pica, N.2    Hai, R.3    Margine, I.4    Palese, P.5
  • 152
    • 84862908804 scopus 로고    scopus 로고
    • Complement-dependent lysis of influenza a virus-infected cells by broadly cross-reactive human monoclonal antibodies
    • Terajima, M.; Cruz, J.; Co, M.D.; Lee, J.H.; Kaur, K.; Wrammert, J.; Wilson, P.C.; Ennis, F.A. Complement-dependent lysis of influenza a virus-infected cells by broadly cross-reactive human monoclonal antibodies. J. Virol. 2011, 85, 13463–13467.
    • (2011) J. Virol , vol.85 , pp. 13463-13467
    • Terajima, M.1    Cruz, J.2    Co, M.D.3    Lee, J.H.4    Kaur, K.5    Wrammert, J.6    Wilson, P.C.7    Ennis, F.A.8
  • 154
    • 33749658275 scopus 로고
    • Immunological studies with the virus of influenza
    • Francis, T.; Magill, T.P. Immunological studies with the virus of influenza. J. Exp. Med. 1935, 62, 505–516.
    • (1935) J. Exp. Med , vol.62 , pp. 505-516
    • Francis, T.1    Magill, T.P.2
  • 155
    • 84909590224 scopus 로고
    • Neutralization tests with sera of convalescent or immunized animals and the viruses of swine and human influenza
    • Francis, T.; Shope, R.E. Neutralization tests with sera of convalescent or immunized animals and the viruses of swine and human influenza. J. Exp. Med. 1936, 63, 645–653.
    • (1936) J. Exp. Med , vol.63 , pp. 645-653
    • Francis, T.1    Shope, R.E.2
  • 158
    • 47549106546 scopus 로고    scopus 로고
    • Molecular cloning and phylogenetic analysis of inflammatory cytokines of the ferret (mustela putorius furo)
    • Nakata, M.; Itou, T.; Sakai, T. Molecular cloning and phylogenetic analysis of inflammatory cytokines of the ferret (mustela putorius furo). J. Vet. Med. Sci./ Jpn. Soc. Vet. Sci. 2008, 70, 543–550.
    • (2008) J. Vet. Med. Sci./ Jpn. Soc. Vet. Sci , vol.70 , pp. 543-550
    • Nakata, M.1    Itou, T.2    Sakai, T.3
  • 160
    • 84897096713 scopus 로고    scopus 로고
    • Evaluation of heterosubtypic cross-protection against highly pathogenic H5N1 by active infection with human seasonal influenza a virus or trivalent inactivated vaccine immunization in ferret models
    • Park, S.J.; Kim, E.H.; Pascua, P.N.; Kwon, H.I.; Lim, G.J.; Decano, A.; Kim, S.M.; Song, M.K.; Shin, E.C.; Choi, Y.K. Evaluation of heterosubtypic cross-protection against highly pathogenic H5N1 by active infection with human seasonal influenza a virus or trivalent inactivated vaccine immunization in ferret models. J. Gen. Virol. 2014, 95, 793–798.
    • (2014) J. Gen. Virol , vol.95 , pp. 793-798
    • Park, S.J.1    Kim, E.H.2    Pascua, P.N.3    Kwon, H.I.4    Lim, G.J.5    Decano, A.6    Kim, S.M.7    Song, M.K.8    Shin, E.C.9    Choi, Y.K.10
  • 161
    • 84899710594 scopus 로고    scopus 로고
    • Humans and ferrets with prior H1N1 influenza virus infections do not exhibit evidence of original antigenic sin after infection or vaccination with the 2009 pandemic H1N1 virus
    • O'Donnell, C.D.; Wright, A.; Vogel, L.; Boonnak, K.; Treanor, J.J.; Subbarao, K. Humans and ferrets with prior H1N1 influenza virus infections do not exhibit evidence of original antigenic sin after infection or vaccination with the 2009 pandemic H1N1 virus. Clin. Vaccine Immunol.: CVI 2014, doi:10.1128/CVI.00790-13.
    • (2014) Clin. Vaccine Immunol.: CVI
    • O'donnell, C.D.1    Wright, A.2    Vogel, L.3    Boonnak, K.4    Treanor, J.J.5    Subbarao, K.6
  • 162
    • 84888066215 scopus 로고    scopus 로고
    • Impact of prior seasonal H3N2 influenza vaccination or infection on protection and transmission of emerging variants of influenza a(H3N2)v virus in ferrets
    • Houser, K.V.; Pearce, M.B.; Katz, J.M.; Tumpey, T.M. Impact of prior seasonal H3N2 influenza vaccination or infection on protection and transmission of emerging variants of influenza a(H3N2)v virus in ferrets. J. Virol. 2013, 87, 13480–13489.
    • (2013) J. Virol , vol.87 , pp. 13480-13489
    • Houser, K.V.1    Pearce, M.B.2    Katz, J.M.3    Tumpey, T.M.4
  • 165
    • 34547837401 scopus 로고    scopus 로고
    • Antigen sparing and cross-reactive immunity with an adjuvanted rH5N1 prototype pandemic influenza vaccine: A randomised controlled trial
    • Leroux-Roels, I.; Borkowski, A.; Vanwolleghem, T.; Drame, M.; Clement, F.; Hons, E.; Devaster, J.M.; Leroux-Roels, G. Antigen sparing and cross-reactive immunity with an adjuvanted rH5N1 prototype pandemic influenza vaccine: A randomised controlled trial. Lancet 2007, 370, 580–589.
    • (2007) Lancet , vol.370 , pp. 580-589
    • Leroux-Roels, I.1    Borkowski, A.2    Vanwolleghem, T.3    Drame, M.4    Clement, F.5    Hons, E.6    Devaster, J.M.7    Leroux-Roels, G.8
  • 167
    • 84901343287 scopus 로고    scopus 로고
    • Development of a high yield live attenuated H7N9 influenza vaccine that provides protection against homologous and heterologous h7 wild-type viruses in ferrets
    • Chen, Z.; Baz, M.; Lu, J.; Paskel, M.; Santos, C.; Subbarao, K.; Jin, H.; Matsuoka, Y. Development of a high yield live attenuated H7N9 influenza vaccine that provides protection against homologous and heterologous h7 wild-type viruses in ferrets. J. Virol. 2014, doi:10.1128/JVI.00100-14.
    • (2014) J. Virol
    • Chen, Z.1    Baz, M.2    Lu, J.3    Paskel, M.4    Santos, C.5    Subbarao, K.6    Jin, H.7    Matsuoka, Y.8
  • 173
    • 84904658491 scopus 로고    scopus 로고
    • African green monkeys recapitulate the clinical experience with replication of live attenuated pandemic influenza virus vaccine candidates
    • Matsuoka, Y.; Suguitan, A.; Orandle, M.; Paskel, M.; Boonnak, K.; Gardner, D.J.; Feldmann, F.; Feldmann, H.; Marino, M.; Jin, H. et al. African green monkeys recapitulate the clinical experience with replication of live attenuated pandemic influenza virus vaccine candidates. J. Virol. 2014, 88, 8139–8152.
    • (2014) J. Virol , vol.88 , pp. 8139-8152
    • Matsuoka, Y.1    Suguitan, A.2    Orandle, M.3    Paskel, M.4    Boonnak, K.5    Gardner, D.J.6    Feldmann, F.7    Feldmann, H.8    Marino, M.9    Jin, H.10
  • 175
    • 4043181266 scopus 로고    scopus 로고
    • Protection of weaned pigs by vaccination with human adenovirus 5 recombinant viruses expressing the hemagglutinin and the nucleoprotein of H3N2 swine influenza virus
    • Wesley, R.D.; Tang, M.; Lager, K.M. Protection of weaned pigs by vaccination with human adenovirus 5 recombinant viruses expressing the hemagglutinin and the nucleoprotein of H3N2 swine influenza virus. Vaccine 2004, 22, 3427–3434.
    • (2004) Vaccine , vol.22 , pp. 3427-3434
    • Wesley, R.D.1    Tang, M.2    Lager, K.M.3
  • 176
    • 84883290809 scopus 로고    scopus 로고
    • An eight-segment swine influenza virus harboring h1 and h3 hemagglutinins is attenuated and protective against H1N1 and H3N2 subtypes in pigs
    • Masic, A.; Pyo, H.M.; Babiuk, S.; Zhou, Y. An eight-segment swine influenza virus harboring h1 and h3 hemagglutinins is attenuated and protective against H1N1 and H3N2 subtypes in pigs. J. Virol. 2013, 87, 10114–10125.
    • (2013) J. Virol , vol.87 , pp. 10114-10125
    • Masic, A.1    Pyo, H.M.2    Babiuk, S.3    Zhou, Y.4
  • 178
    • 79952411472 scopus 로고    scopus 로고
    • Efficacy of vaccination with different combinations of mf59-adjuvanted and nonadjuvanted seasonal and pandemic influenza vaccines against pandemic H1N1 (2009) influenza virus infection in ferrets
    • Van den Brand, J.M.; Kreijtz, J.H.; Bodewes, R.; Stittelaar, K.J.; van Amerongen, G.; Kuiken, T.; Simon, J.; Fouchier, R.A.; Del Giudice, G.; Rappuoli, R. et al. Efficacy of vaccination with different combinations of mf59-adjuvanted and nonadjuvanted seasonal and pandemic influenza vaccines against pandemic H1N1 (2009) influenza virus infection in ferrets. J. Virol. 2011, 85, 2851–2858.
    • (2011) J. Virol , vol.85 , pp. 2851-2858
    • Van Den Brand, J.M.1    Kreijtz, J.H.2    Bodewes, R.3    Stittelaar, K.J.4    Van Amerongen, G.5    Kuiken, T.6    Simon, J.7    Fouchier, R.A.8    Del Giudice, G.9    Rappuoli, R.10
  • 179
    • 79954632010 scopus 로고    scopus 로고
    • Impact of prior seasonal influenza vaccination and infection on pandemic a (H1N1) influenza virus replication in ferrets
    • Ellebedy, A.H.; Ducatez, M.F.; Duan, S.; Stigger-Rosser, E.; Rubrum, A.M.; Govorkova, E.A.; Webster, R.G.; Webby, R.J. Impact of prior seasonal influenza vaccination and infection on pandemic a (H1N1) influenza virus replication in ferrets. Vaccine 2011, 29, 3335–3339.
    • (2011) Vaccine , vol.29 , pp. 3335-3339
    • Ellebedy, A.H.1    Ducatez, M.F.2    Duan, S.3    Stigger-Rosser, E.4    Rubrum, A.M.5    Govorkova, E.A.6    Webster, R.G.7    Webby, R.J.8
  • 180
    • 79953000340 scopus 로고    scopus 로고
    • Comparison of a live attenuated 2009 h1n1 vaccine with seasonal influenza vaccines against 2009 pandemic H1N1 virus infection in mice and ferrets
    • Chen, G.L.; Min, J.Y.; Lamirande, E.W.; Santos, C.; Jin, H.; Kemble, G.; Subbarao, K. Comparison of a live attenuated 2009 h1n1 vaccine with seasonal influenza vaccines against 2009 pandemic H1N1 virus infection in mice and ferrets. J. Infect. Dis. 2011, 203, 930–936.
    • (2011) J. Infect. Dis. , vol.203 , pp. 930-936
    • Chen, G.L.1    Min, J.Y.2    Lamirande, E.W.3    Santos, C.4    Jin, H.5    Kemble, G.6    Subbarao, K.7
  • 181
    • 36749040282 scopus 로고    scopus 로고
    • Failure of protection and enhanced pneumonia with a us H1N2 swine influenza virus in pigs vaccinated with an inactivated classical swine H1N1 vaccine
    • Vincent, A.L.; Lager, K.M.; Janke, B.H.; Gramer, M.R.; Richt, J.A. Failure of protection and enhanced pneumonia with a us H1N2 swine influenza virus in pigs vaccinated with an inactivated classical swine H1N1 vaccine. Vet. Microbiol. 2008, 126, 310–323.
    • (2008) Vet. Microbiol , vol.126 , pp. 310-323
    • Vincent, A.L.1    Lager, K.M.2    Janke, B.H.3    Gramer, M.R.4    Richt, J.A.5
  • 182
    • 2442587211 scopus 로고    scopus 로고
    • Genetic relationships, serological cross-reaction and cross-protection between H1N2 and other influenza a virus subtypes endemic in european pigs
    • Reeth, K.V.; Brown, I.; Essen, S.; Pensaert, M. Genetic relationships, serological cross-reaction and cross-protection between H1N2 and other influenza a virus subtypes endemic in european pigs. Virus Res. 2004, 103, 115–124.
    • (2004) Virus Res , vol.103 , pp. 115-124
    • Reeth, K.V.1    Brown, I.2    Essen, S.3    Pensaert, M.4
  • 183
    • 0031951165 scopus 로고    scopus 로고
    • Immunization of pigs with a particle-mediated dna vaccine to influenza a virus protects against challenge with homologous virus
    • Macklin, M.D.; McCabe, D.; McGregor, M.W.; Neumann, V.; Meyer, T.; Callan, R.; Hinshaw, V.S.; Swain, W.F. Immunization of pigs with a particle-mediated dna vaccine to influenza a virus protects against challenge with homologous virus. J. Virol. 1998, 72, 1491–1496.
    • (1998) J. Virol , vol.72 , pp. 1491-1496
    • Macklin, M.D.1    McCabe, D.2    McGregor, M.W.3    Neumann, V.4    Meyer, T.5    Callan, R.6    Hinshaw, V.S.7    Swain, W.F.8
  • 184
    • 84868262601 scopus 로고    scopus 로고
    • Kinetics of lung lesion development and pro-inflammatory cytokine response in pigs with vaccine-associated enhanced respiratory disease induced by challenge with pandemic (2009) a/H1N1 influenza virus
    • Gauger, P.C.; Vincent, A.L.; Loving, C.L.; Henningson, J.N.; Lager, K.M.; Janke, B.H.; Kehrli, M.E., Jr.; Roth, J.A. Kinetics of lung lesion development and pro-inflammatory cytokine response in pigs with vaccine-associated enhanced respiratory disease induced by challenge with pandemic (2009) a/H1N1 influenza virus. Vet. Pathol. 2012, 49, 900–912.
    • (2012) Vet. Pathol , vol.49 , pp. 900-912
    • Gauger, P.C.1    Vincent, A.L.2    Loving, C.L.3    Henningson, J.N.4    Lager, K.M.5    Janke, B.H.6    Kehrli, M.E.7    Roth, J.A.8
  • 185
    • 79952244491 scopus 로고    scopus 로고
    • Enhanced pneumonia and disease in pigs vaccinated with an inactivated human-like (delta-cluster) H1N2 vaccine and challenged with pandemic 2009 H1N1 influenza virus
    • Gauger, P.C.; Vincent, A.L.; Loving, C.L.; Lager, K.M.; Janke, B.H.; Kehrli, M.E., Jr.; Roth, J.A. Enhanced pneumonia and disease in pigs vaccinated with an inactivated human-like (delta-cluster) H1N2 vaccine and challenged with pandemic 2009 H1N1 influenza virus. Vaccine 2011, 29, 2712–2719.
    • (2011) Vaccine , vol.29 , pp. 2712-2719
    • Gauger, P.C.1    Vincent, A.L.2    Loving, C.L.3    Lager, K.M.4    Janke, B.H.5    Kehrli, M.E.6    Roth, J.A.7
  • 186
    • 77954814729 scopus 로고    scopus 로고
    • Efficacy of commercial swine influenza vaccines against challenge with a recent european H1N1 field isolate
    • Kyriakis, C.S.; Gramer, M.R.; Barbe, F.; van Doorsselaere, J.; van Reeth, K. Efficacy of commercial swine influenza vaccines against challenge with a recent european H1N1 field isolate. Vet. Microbiol. 2010, 144, 67–74.
    • (2010) Vet. Microbiol , vol.144 , pp. 67-74
    • Kyriakis, C.S.1    Gramer, M.R.2    Barbe, F.3    Van Doorsselaere, J.4    Van Reeth, K.5
  • 187
    • 0035859995 scopus 로고    scopus 로고
    • Efficacy of vaccination of pigs with different H1N1 swine influenza viruses using a recent challenge strain and different parameters of protection
    • Van Reeth, K.; Labarque, G.; de Clercq, S.; Pensaert, M. Efficacy of vaccination of pigs with different H1N1 swine influenza viruses using a recent challenge strain and different parameters of protection. Vaccine 2001, 19, 4479–4486.
    • (2001) Vaccine , vol.19 , pp. 4479-4486
    • Van Reeth, K.1    Labarque, G.2    De Clercq, S.3    Pensaert, M.4
  • 188
    • 0038719157 scopus 로고    scopus 로고
    • Investigations of the efficacy of european H1N1- and H3N2-based swine influenza vaccines against the novel H1N2 subtype
    • Van Reeth, K.; Van Gucht, S.; Pensaert, M. Investigations of the efficacy of european H1N1- and H3N2-based swine influenza vaccines against the novel H1N2 subtype. Vet. Rec. 2003, 153, 9–0
    • (2003) Vet. Rec , vol.153 , pp. 9
    • Van Reeth, K.1    Van Gucht, S.2    Pensaert, M.3
  • 189
    • 84869054575 scopus 로고    scopus 로고
    • Live attenuated influenza vaccine provides superior protection from heterologous infection in pigs with maternal antibodies without inducing vaccineassociated enhanced respiratory disease
    • Vincent, A.L.; Ma, W.; Lager, K.M.; Richt, J.A.; Janke, B.H.; Sandbulte, M.R.; Gauger, P.C.; Loving, C.L.; Webby, R.J.; Garcia-Sastre, A. Live attenuated influenza vaccine provides superior protection from heterologous infection in pigs with maternal antibodies without inducing vaccineassociated enhanced respiratory disease. J. Virol. 2012, 86, 10597–10605.
    • (2012) J. Virol , vol.86 , pp. 10597-10605
    • Vincent, A.L.1    Ma, W.2    Lager, K.M.3    Richt, J.A.4    Janke, B.H.5    Sandbulte, M.R.6    Gauger, P.C.7    Loving, C.L.8    Webby, R.J.9    Garcia-Sastre, A.10
  • 190
    • 84868231731 scopus 로고    scopus 로고
    • Intranasal vaccination with replication-defective adenovirus type 5 encoding influenza virus hemagglutinin elicits protective immunity to homologous challenge and partial protection to heterologous challenge in pigs
    • Braucher, D.R.; Henningson, J.N.; Loving, C.L.; Vincent, A.L.; Kim, E.; Steitz, J.; Gambotto, A.A.; Kehrli, M.E., Jr. Intranasal vaccination with replication-defective adenovirus type 5 encoding influenza virus hemagglutinin elicits protective immunity to homologous challenge and partial protection to heterologous challenge in pigs. Clin. Vaccine Immunol.: CVI 2012, 19, 1722–1729.
    • (2012) Clin. Vaccine Immunol.: CVI , vol.19 , pp. 1722-1729
    • Braucher, D.R.1    Henningson, J.N.2    Loving, C.L.3    Vincent, A.L.4    Kim, E.5    Steitz, J.6    Gambotto, A.A.7    Kehrli, M.E.8
  • 191
    • 84864303662 scopus 로고    scopus 로고
    • Efficacy of an as03a-adjuvanted split H5N1 influenza vaccine against an antigenically distinct low pathogenic H5N1 virus in pigs
    • De Vleeschauwer, A.R.; Baras, B.; Kyriakis, C.S.; Jacob, V.; Planty, C.; Giannini, S.L.; Mossman, S.; van Reeth, K. Efficacy of an as03a-adjuvanted split H5N1 influenza vaccine against an antigenically distinct low pathogenic H5N1 virus in pigs. Vaccine 2012, 30, 5557–5563.
    • (2012) Vaccine , vol.30 , pp. 5557-5563
    • De Vleeschauwer, A.R.1    Baras, B.2    Kyriakis, C.S.3    Jacob, V.4    Planty, C.5    Giannini, S.L.6    Mossman, S.7    Van Reeth, K.8
  • 195
  • 199
    • 0036330730 scopus 로고    scopus 로고
    • Vaccination of pigs with a dna construct expressing an influenza virus m2-nucleoprotein fusion protein exacerbates disease after challenge with influenza a virus
    • Heinen, P.P.; Rijsewijk, F.A.; de Boer-Luijtze, E.A.; Bianchi, A.T. Vaccination of pigs with a dna construct expressing an influenza virus m2-nucleoprotein fusion protein exacerbates disease after challenge with influenza a virus. J. Gen. Virol. 2002, 83, 1851–1859.
    • (2002) J. Gen. Virol , vol.83 , pp. 1851-1859
    • Heinen, P.P.1    Rijsewijk, F.A.2    De Boer-Luijtze, E.A.3    Bianchi, A.T.4
  • 201
    • 0033523050 scopus 로고    scopus 로고
    • Influenza virus subtype cross-reactivities of haemagglutination inhibiting and virus neutralising serum antibodies induced by infection or vaccination with an iscom-based vaccine
    • Rimmelzwaan, G.F.; Baars, M.; van Beek, R.; de Lijster, P.; de Jong, J.C.; Claas, E.C.; Osterhaus, A.D. Influenza virus subtype cross-reactivities of haemagglutination inhibiting and virus neutralising serum antibodies induced by infection or vaccination with an iscom-based vaccine. Vaccine 1999, 17, 2512–2516.
    • (1999) Vaccine , vol.17 , pp. 2512-2516
    • Rimmelzwaan, G.F.1    Baars, M.2    Van Beek, R.3    De Lijster, P.4    De Jong, J.C.5    Claas, E.C.6    Osterhaus, A.D.7
  • 202
    • 67249149634 scopus 로고    scopus 로고
    • Immunogenicity and protective efficacy of a live attenuated H5N1 vaccine in nonhuman primates
    • Fan, S.; Gao, Y.; Shinya, K.; Li, C.K.; Li, Y.; Shi, J.; Jiang, Y.; Suo, Y.; Tong, T.; Zhong, G. et al. Immunogenicity and protective efficacy of a live attenuated H5N1 vaccine in nonhuman primates. PLoS Pathog. 2009, 5, e1000409.
    • (2009) Plos Pathog , vol.5 , pp. 1000409
    • Fan, S.1    Gao, Y.2    Shinya, K.3    Li, C.K.4    Li, Y.5    Shi, J.6    Jiang, Y.7    Suo, Y.8    Tong, T.9    Zhong, G.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.