메뉴 건너뛰기




Volumn 7, Issue 48, 2016, Pages 78726-78735

MFHAS1 promotes colorectal cancer progress by regulating polarization of tumor-associated macrophages via STAT6 signaling pathway

Author keywords

Colorectal cancer; Macrophage polarization; MFHAS1; Tumor associated macrophages

Indexed keywords

KRUPPEL LIKE FACTOR 4; ONCOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN MFHAS1; ROSIGLITAZONE; STAT6 PROTEIN; UNCLASSIFIED DRUG; 2,4 THIAZOLIDINEDIONE DERIVATIVE; CELL CYCLE PROTEIN; CELL SURFACE RECEPTOR; DNA BINDING PROTEIN; KRUPPEL LIKE FACTOR; LECTIN; MANNOSE BINDING LECTIN; MANNOSE RECEPTOR; MFHAS1 PROTEIN, HUMAN; STAT6 PROTEIN, MOUSE;

EID: 84998854318     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.12807     Document Type: Article
Times cited : (34)

References (39)
  • 1
    • 77950285012 scopus 로고    scopus 로고
    • Neutrophils and macrophages work in concert as inducers and effectors of adaptive immunity against extracellular and intracellular microbial pathogens
    • Silva MT. Neutrophils and macrophages work in concert as inducers and effectors of adaptive immunity against extracellular and intracellular microbial pathogens. J Leukoc Biol. 2010; 87:805-13.
    • (2010) J Leukoc Biol , vol.87 , pp. 805-813
    • Silva, M.T.1
  • 2
    • 84863279872 scopus 로고    scopus 로고
    • Emerging role of mast cells and macrophages in cardiovascular and metabolic diseases
    • Xu JM, Shi GP. Emerging role of mast cells and macrophages in cardiovascular and metabolic diseases. Endocr Rev. 2012; 33:71-108.
    • (2012) Endocr Rev , vol.33 , pp. 71-108
    • Xu, J.M.1    Shi, G.P.2
  • 3
    • 84893711468 scopus 로고    scopus 로고
    • Macrophages. supportive cells for tissue repair and regeneration
    • Chazaud B. Macrophages. supportive cells for tissue repair and regeneration. Immunobiology. 2014; 219:172-8.
    • (2014) Immunobiology , vol.219 , pp. 172-178
    • Chazaud, B.1
  • 4
    • 84926523845 scopus 로고    scopus 로고
    • Macrophages and cancer: from mechanisms to therapeutic implications
    • Ostuni R, Kratochvill F, Murray PJ, Natoli G. Macrophages and cancer: from mechanisms to therapeutic implications. Trends Immunol. 2015; 36:229-39.
    • (2015) Trends Immunol , vol.36 , pp. 229-239
    • Ostuni, R.1    Kratochvill, F.2    Murray, P.J.3    Natoli, G.4
  • 5
    • 84960801240 scopus 로고    scopus 로고
    • Macrophages: Key regulators of steady-state and demand-adapted hematopoiesis
    • McCabe A, MacNamara KC. Macrophages: Key regulators of steady-state and demand-adapted hematopoiesis. Exp Hematol. 2016; 44:213-22.
    • (2016) Exp Hematol , vol.44 , pp. 213-222
    • McCabe, A.1    MacNamara, K.C.2
  • 6
    • 26644452073 scopus 로고    scopus 로고
    • Macrophage polarization comes of age
    • Mantovani A, Sica A, Locati M. Macrophage polarization comes of age. Immunity 2005; 23:344-6.
    • (2005) Immunity , vol.23 , pp. 344-346
    • Mantovani, A.1    Sica, A.2    Locati, M.3
  • 7
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol. 2008; 8:958-69.
    • (2008) Nat Rev Immunol , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 8
    • 33846352854 scopus 로고    scopus 로고
    • New vistas on macrophage differentiation and activation
    • Mantovani A, Sica A, Locati M. New vistas on macrophage differentiation and activation. Eur J Immunol. 2007; 37:14-6.
    • (2007) Eur J Immunol , vol.37 , pp. 14-16
    • Mantovani, A.1    Sica, A.2    Locati, M.3
  • 10
    • 84920943285 scopus 로고    scopus 로고
    • Tumorassociated macrophages as major players in the tumor microenvironment
    • Chanmee T, Ontong P, Konno K, Itano N. Tumorassociated macrophages as major players in the tumor microenvironment. Cancers (Basel). 2014; 6:1670-90.
    • (2014) Cancers (Basel) , vol.6 , pp. 1670-1690
    • Chanmee, T.1    Ontong, P.2    Konno, K.3    Itano, N.4
  • 11
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer. 2004; 4:71-8
    • (2004) Nat Rev Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 12
    • 77950950894 scopus 로고    scopus 로고
    • Macrophage diversity enhances tumor progression and metastasis
    • Qian BZ, Pollard JW. Macrophage diversity enhances tumor progression and metastasis. Cell. 2010; 141:39-51.
    • (2010) Cell , vol.141 , pp. 39-51
    • Qian, B.Z.1    Pollard, J.W.2
  • 13
    • 84871661615 scopus 로고    scopus 로고
    • M2/M1 ratio of tumor associated macrophages and PPAR-gamma expression in uveal melanomas with class 1 and class 2 molecular profiles
    • Herwig MC, Bergstrom C, Wells JR, Holler T, Grossniklaus HE. M2/M1 ratio of tumor associated macrophages and PPAR-gamma expression in uveal melanomas with class 1 and class 2 molecular profiles. Exp Eye Res. 2013; 107:52-8.
    • (2013) Exp Eye Res , vol.107 , pp. 52-58
    • Herwig, M.C.1    Bergstrom, C.2    Wells, J.R.3    Holler, T.4    Grossniklaus, H.E.5
  • 14
    • 84928141330 scopus 로고    scopus 로고
    • High infiltration of tumor-associated macrophages is associated with a poor response to chemotherapy and poor prognosis of patients undergoing neoadjuvant chemotherapy for esophageal cancer
    • Sugimura K, Miyata H, Tanaka K, Takahashi T, Kurokawa Y, Yamasaki M, Nakajima K, Takiguchi S, Mori M, Doki Y. High infiltration of tumor-associated macrophages is associated with a poor response to chemotherapy and poor prognosis of patients undergoing neoadjuvant chemotherapy for esophageal cancer. J Surg Oncol. 2015; 111:752-9.
    • (2015) J Surg Oncol , vol.111 , pp. 752-759
    • Sugimura, K.1    Miyata, H.2    Tanaka, K.3    Takahashi, T.4    Kurokawa, Y.5    Yamasaki, M.6    Nakajima, K.7    Takiguchi, S.8    Mori, M.9    Doki, Y.10
  • 15
    • 84953296867 scopus 로고    scopus 로고
    • The M2 phenotype of tumor-associated macrophages in the stroma confers a poor prognosis in pancreatic cancer
    • Hu H, Hang JJ, Han T, Zhuo M, Jiao F, Wang LW. The M2 phenotype of tumor-associated macrophages in the stroma confers a poor prognosis in pancreatic cancer. Tumour Biol. 2016; 37:8657-64.
    • (2016) Tumour Biol , vol.37 , pp. 8657-8664
    • Hu, H.1    Hang, J.J.2    Han, T.3    Zhuo, M.4    Jiao, F.5    Wang, L.W.6
  • 16
    • 84957824859 scopus 로고    scopus 로고
    • Tumorassociated macrophages: Potential therapeutic targets for anti-cancer therapy
    • Komohara Y, Fujiwara Y, Ohnishi K, Takeya M. Tumorassociated macrophages: Potential therapeutic targets for anti-cancer therapy. Adv Drug Deliv Rev. 2016; 99:180-5.
    • (2016) Adv Drug Deliv Rev , vol.99 , pp. 180-185
    • Komohara, Y.1    Fujiwara, Y.2    Ohnishi, K.3    Takeya, M.4
  • 17
    • 84880740892 scopus 로고    scopus 로고
    • Clinical significance of CD163(+) tumor-associated macrophages in patients with adult T-cell leukemia/lymphoma
    • Komohara Y, Niino D, Saito Y, Ohnishi K, Horlad H, Ohshima K, Takeya M. Clinical significance of CD163(+) tumor-associated macrophages in patients with adult T-cell leukemia/lymphoma. Cancer Sci. 2013; 104:945-51.
    • (2013) Cancer Sci , vol.104 , pp. 945-951
    • Komohara, Y.1    Niino, D.2    Saito, Y.3    Ohnishi, K.4    Horlad, H.5    Ohshima, K.6    Takeya, M.7
  • 18
    • 84929224674 scopus 로고    scopus 로고
    • Larynx carcinoma regulates tumor-associated macrophages through PLGF signaling
    • Zhou X, Qi Y. Larynx carcinoma regulates tumor-associated macrophages through PLGF signaling. Sci Rep. 2015; 5:10071.
    • (2015) Sci Rep , vol.5 , pp. 10071
    • Zhou, X.1    Qi, Y.2
  • 19
    • 0033083906 scopus 로고    scopus 로고
    • Identification of a novel gene, MASL1, within an amplicon at 8p23.1 detected in malignant fibrous histiocytomas by comparative genomic hybridization
    • Sakabe T, Shinomiya T, Mori T, Ariyama Y, Fukuda Y, Fujiwara T, Nakamura Y, Inazawa J. Identification of a novel gene, MASL1, within an amplicon at 8p23.1 detected in malignant fibrous histiocytomas by comparative genomic hybridization. Cancer Res. 1999; 59:511-5.
    • (1999) Cancer Res , vol.59 , pp. 511-515
    • Sakabe, T.1    Shinomiya, T.2    Mori, T.3    Ariyama, Y.4    Fukuda, Y.5    Fujiwara, T.6    Nakamura, Y.7    Inazawa, J.8
  • 20
    • 1942501050 scopus 로고    scopus 로고
    • MASL1, a candidate oncogene found in amplification at 8p23.1, is translocated in immunoblastic B-cell lymphoma cell line OCI-LY8
    • Tagawa H, Karnan S, Kasugai Y, Tuzuki S, Suzuki R, Hosokawa Y, Seto M. MASL1, a candidate oncogene found in amplification at 8p23.1, is translocated in immunoblastic B-cell lymphoma cell line OCI-LY8. Oncogene. 2004; 23:2576-81.
    • (2004) Oncogene , vol.23 , pp. 2576-2581
    • Tagawa, H.1    Karnan, S.2    Kasugai, Y.3    Tuzuki, S.4    Suzuki, R.5    Hosokawa, Y.6    Seto, M.7
  • 21
    • 84866716156 scopus 로고    scopus 로고
    • MASL1: a neglected ROCO protein
    • Dihanich S. MASL1: a neglected ROCO protein. Biochem Soc Trans. 2012; 40:1090-4.
    • (2012) Biochem Soc Trans , vol.40 , pp. 1090-1094
    • Dihanich, S.1
  • 24
    • 84860883332 scopus 로고    scopus 로고
    • Vitamin E forms inhibit IL-13/STAT6-induced eotaxin-3 secretion by up-regulation of PAR4, an endogenous inhibitor of atypical PKC in human lung epithelial cells
    • Wang Y, Moreland M, Wagner JG, Ames BN, Illek B, Peden DB, Jiang Q. Vitamin E forms inhibit IL-13/STAT6-induced eotaxin-3 secretion by up-regulation of PAR4, an endogenous inhibitor of atypical PKC in human lung epithelial cells. J Nutr Biochem. 2012; 23:602-8.
    • (2012) J Nutr Biochem , vol.23 , pp. 602-608
    • Wang, Y.1    Moreland, M.2    Wagner, J.G.3    Ames, B.N.4    Illek, B.5    Peden, D.B.6    Jiang, Q.7
  • 25
    • 84922799330 scopus 로고    scopus 로고
    • Interaction between pancreatic cancer cells and tumor-associated macrophages promotes the invasion of pancreatic cancer cells and the differentiation and migration of macrophages
    • Meng F, Li C, Li W, Gao Z, Guo K, Song S: Interaction between pancreatic cancer cells and tumor-associated macrophages promotes the invasion of pancreatic cancer cells and the differentiation and migration of macrophages. IUBMB Life. 2014; 66:835-46.
    • (2014) IUBMB Life , vol.66 , pp. 835-846
    • Meng, F.1    Li, C.2    Li, W.3    Gao, Z.4    Guo, K.5    Song, S.6
  • 28
    • 84934290620 scopus 로고    scopus 로고
    • Ovarian cancer stem cells induce the M2 polarization of macrophages through the PPARgamma and NF-kappaB pathways
    • Deng X, Zhang P, Liang T, Deng S, Chen X, Zhu L. Ovarian cancer stem cells induce the M2 polarization of macrophages through the PPARgamma and NF-kappaB pathways. Int J Mol Med. 2015; 36:449-54.
    • (2015) Int J Mol Med , vol.36 , pp. 449-454
    • Deng, X.1    Zhang, P.2    Liang, T.3    Deng, S.4    Chen, X.5    Zhu, L.6
  • 29
    • 34249099761 scopus 로고    scopus 로고
    • The PPARgamma agonist rosiglitazone impairs colonic inflammation in mice with experimental colitis
    • Ramakers JD, Verstege MI, Thuijls G, Te VA, Mensink RP, Plat J. The PPARgamma agonist rosiglitazone impairs colonic inflammation in mice with experimental colitis. J Clin Immunol. 2007; 27:275-83.
    • (2007) J Clin Immunol , vol.27 , pp. 275-283
    • Ramakers, J.D.1    Verstege, M.I.2    Thuijls, G.3    Te, V.A.4    Mensink, R.P.5    Plat, J.6
  • 30
    • 84920943285 scopus 로고    scopus 로고
    • Tumorassociated macrophages as major players in the tumor microenvironment
    • Chanmee T, Ontong P, Konno K, Itano N. Tumorassociated macrophages as major players in the tumor microenvironment. Cancers (Basel). 2014; 6:1670-90.
    • (2014) Cancers (Basel) , vol.6 , pp. 1670-1690
    • Chanmee, T.1    Ontong, P.2    Konno, K.3    Itano, N.4
  • 31
    • 84991311768 scopus 로고    scopus 로고
    • Role of tumor-associated macrophages in human malignancies: friend or foe?
    • Takeya M, Komohara Y. Role of tumor-associated macrophages in human malignancies: friend or foe? Pathol Int. 2016; 66:491-505.
    • (2016) Pathol Int , vol.66 , pp. 491-505
    • Takeya, M.1    Komohara, Y.2
  • 33
    • 84920126518 scopus 로고    scopus 로고
    • Antitumor and antimetastatic actions of dihydroxycoumarins (esculetin or fraxetin) through the inhibition of M2 macrophage differentiation in tumor-associated macrophages and/or G1 arrest in tumor cells
    • Kimura Y, Sumiyoshi M. Antitumor and antimetastatic actions of dihydroxycoumarins (esculetin or fraxetin) through the inhibition of M2 macrophage differentiation in tumor-associated macrophages and/or G1 arrest in tumor cells. Eur J Pharmacol. 2015; 746:115-25.
    • (2015) Eur J Pharmacol , vol.746 , pp. 115-125
    • Kimura, Y.1    Sumiyoshi, M.2
  • 35
    • 84958055104 scopus 로고    scopus 로고
    • Antitumor and Antimetastatic Activity of Synthetic Hydroxystilbenes Through Inhibition of Lymphangiogenesis and M2 Macrophage Differentiation of Tumor-associated Macrophages
    • Kimura Y, Sumiyoshi M, Baba K. Antitumor and Antimetastatic Activity of Synthetic Hydroxystilbenes Through Inhibition of Lymphangiogenesis and M2 Macrophage Differentiation of Tumor-associated Macrophages. Anticancer Res. 2016; 36:137-48.
    • (2016) Anticancer Res , vol.36 , pp. 137-148
    • Kimura, Y.1    Sumiyoshi, M.2    Baba, K.3
  • 36
    • 79952742148 scopus 로고    scopus 로고
    • Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity
    • Ng AC, Eisenberg JM, Heath RJ, Huett A, Robinson CM, Nau GJ, Xavier RJ. Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity. Proc Natl Acad Sci USA. 2011; 108:4631-8.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 4631-4638
    • Ng, A.C.1    Eisenberg, J.M.2    Heath, R.J.3    Huett, A.4    Robinson, C.M.5    Nau, G.J.6    Xavier, R.J.7
  • 37
    • 84957990919 scopus 로고    scopus 로고
    • MFHAS1 Is Associated with Sepsis and Stimulates TLR2/NF-kappaB Signaling Pathway Following Negative Regulation
    • Zhong J, Shi QQ, Zhu MM, Shen J, Wang HH, Ma D, Miao CH. MFHAS1 Is Associated with Sepsis and Stimulates TLR2/NF-kappaB Signaling Pathway Following Negative Regulation. PLoS One. 2015; 10:e0143662.
    • (2015) PLoS One , vol.10
    • Zhong, J.1    Shi, Q.Q.2    Zhu, M.M.3    Shen, J.4    Wang, H.H.5    Ma, D.6    Miao, C.H.7
  • 38
    • 84871668861 scopus 로고    scopus 로고
    • Activation of PPARgamma in myeloid cells promotes lung cancer progression and metastasis
    • Nemenoff R. Activation of PPARgamma in myeloid cells promotes lung cancer progression and metastasis. Oncoimmunology. 2012; 1:403-404.
    • (2012) Oncoimmunology , vol.1 , pp. 403-404
    • Nemenoff, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.