메뉴 건너뛰기




Volumn 66, Issue 9, 2016, Pages 491-505

Role of tumor-associated macrophages in human malignancies: friend or foe?

Author keywords

human malignant tumors; immunohistochemistry; M1 M2 macrophage subtypes; tumor associated macrophages

Indexed keywords

B CELL LYMPHOMA; BILE DUCT CARCINOMA; BLADDER CARCINOMA; BREAST CANCER; CANCER TISSUE; COLORECTAL CANCER; DISEASE ASSOCIATION; ENDOMETRIUM CANCER; ESOPHAGUS CANCER; GLIOMA; HODGKIN DISEASE; HUMAN; HUMAN CELL; KIDNEY CARCINOMA; LIVER CELL CARCINOMA; LUNG CANCER; MACROPHAGE; MACROPHAGE FUNCTION; MACROPHAGE POLARIZATION; MALIGNANT NEOPLASTIC DISEASE; MELANOMA; MONOCYTE; NONHODGKIN LYMPHOMA; OVARY CARCINOMA; PANCREAS CANCER; PRIORITY JOURNAL; PROSTATE CANCER; REVIEW; STOMACH CANCER; T CELL LYMPHOMA; THYROID CANCER; TRANSITIONAL CELL CARCINOMA; TUMOR ASSOCIATED LEUKOCYTE; TUMOR GROWTH; TUMOR MICROENVIRONMENT; UTERINE CERVIX CANCER; IMMUNOLOGY; NEOPLASM; PATHOLOGY;

EID: 84991311768     PISSN: 13205463     EISSN: 14401827     Source Type: Journal    
DOI: 10.1111/pin.12440     Document Type: Review
Times cited : (147)

References (150)
  • 1
    • 0036187615 scopus 로고    scopus 로고
    • The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
    • Bingle L, Brown NJ, Lewis CE. The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies. J Pathol 2002; 196: 254–5.
    • (2002) J Pathol , vol.196 , pp. 254-255
    • Bingle, L.1    Brown, N.J.2    Lewis, C.E.3
  • 2
    • 31544441610 scopus 로고    scopus 로고
    • Distinct role of macrophages in different tumor microenvironments
    • Lewis CE, Pollard JW. Distinct role of macrophages in different tumor microenvironments. Cancer Res 2006; 66: 605–12.
    • (2006) Cancer Res , vol.66 , pp. 605-612
    • Lewis, C.E.1    Pollard, J.W.2
  • 3
    • 84892865013 scopus 로고    scopus 로고
    • Clinical significance of macrophage heterogeneity in human malignant tumors
    • Komohara Y, Jinushi M, Takeya M. Clinical significance of macrophage heterogeneity in human malignant tumors. Cancer Sci 2014; 105: 1–8.
    • (2014) Cancer Sci , vol.105 , pp. 1-8
    • Komohara, Y.1    Jinushi, M.2    Takeya, M.3
  • 5
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 2004; 4: 71–8.
    • (2004) Nat Rev Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 6
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • Mantovani A, Sozzani S, Locati M, Allavena P, Sica A. Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 2002; 23: 549–55.
    • (2002) Trends Immunol , vol.23 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 7
    • 0027314001 scopus 로고
    • Detection of monocyte chemoattractant protein-1 in human atherosclerotic lesions by an anti-monocyte chemoattractant protein-1 monoclonal antibody
    • Takeya M, Yoshimura T, Leonard EJ, Takahashi K. Detection of monocyte chemoattractant protein-1 in human atherosclerotic lesions by an anti-monocyte chemoattractant protein-1 monoclonal antibody. Hum Pathol 1993; 24: 534–9.
    • (1993) Hum Pathol , vol.24 , pp. 534-539
    • Takeya, M.1    Yoshimura, T.2    Leonard, E.J.3    Takahashi, K.4
  • 8
    • 78149360132 scopus 로고    scopus 로고
    • Fate mapping analysis reveals that adult microglia derive from primitive macrophages
    • Ginhoux F, Greter M, Leboeuf M et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science 2010; 330: 841–5.
    • (2010) Science , vol.330 , pp. 841-845
    • Ginhoux, F.1    Greter, M.2    Leboeuf, M.3
  • 9
    • 0014325451 scopus 로고
    • The origin and kinetics of mononuclear phagocytes
    • van Furth R, Cohn ZA. The origin and kinetics of mononuclear phagocytes. J Exp Med 1968; 128: 415–35.
    • (1968) J Exp Med , vol.128 , pp. 415-435
    • van Furth, R.1    Cohn, Z.A.2
  • 10
    • 80052069274 scopus 로고    scopus 로고
    • Characteristics of the alternative phenotype of microglia/macrophages and its modulation in experimental gliomas
    • Gabrusiewicz K, Ellert-Miklaszewska A, Lipko M, Sielska M, Frankowska M, Kaminska B. Characteristics of the alternative phenotype of microglia/macrophages and its modulation in experimental gliomas. PLoS One 2011; 6 :e23902
    • (2011) PLoS One , vol.6 , pp. e23902
    • Gabrusiewicz, K.1    Ellert-Miklaszewska, A.2    Lipko, M.3    Sielska, M.4    Frankowska, M.5    Kaminska, B.6
  • 12
    • 84904394690 scopus 로고    scopus 로고
    • Macophage activation and polarization: Nomenclature and experimental guidelines
    • Murray PJ, Allen JE, Biswas SK et al. Macophage activation and polarization: Nomenclature and experimental guidelines. Immunity 2014; 41: 14–20.
    • (2014) Immunity , vol.41 , pp. 14-20
    • Murray, P.J.1    Allen, J.E.2    Biswas, S.K.3
  • 13
    • 0028243802 scopus 로고
    • Interleukin-13 alters the activation state of murine macrophages in vitro: comparison with interleukin-4 and interferon-gamma
    • Doyle AG, Herbein G, Montaner LJ et al. Interleukin-13 alters the activation state of murine macrophages in vitro: comparison with interleukin-4 and interferon-gamma. Eur J Immunol 1994; 24: 1441–5.
    • (1994) Eur J Immunol , vol.24 , pp. 1441-1445
    • Doyle, A.G.1    Herbein, G.2    Montaner, L.J.3
  • 15
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol 2008; 8: 958–69.
    • (2008) Nat Rev Immunol , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 16
    • 42149099408 scopus 로고    scopus 로고
    • Plasticity of macrophage function during tumor progression: Regulation by distinct molecular mechanisms
    • Biswas SK, Sica A, Lewis CE. Plasticity of macrophage function during tumor progression: Regulation by distinct molecular mechanisms. J Immunol 2008; 180: 2011–17.
    • (2008) J Immunol , vol.180 , pp. 2011-2017
    • Biswas, S.K.1    Sica, A.2    Lewis, C.E.3
  • 17
    • 67650485985 scopus 로고    scopus 로고
    • Alternative activation of macrophages: An immunologic functional perspective
    • Martinez FO, Helming L, Gordon S. Alternative activation of macrophages: An immunologic functional perspective. Annu Rev Immunol 2009; 27: 451–83.
    • (2009) Annu Rev Immunol , vol.27 , pp. 451-483
    • Martinez, F.O.1    Helming, L.2    Gordon, S.3
  • 18
    • 84897556094 scopus 로고    scopus 로고
    • The M1 and M2 paradigm of macrophage activation: time for reassessment
    • Martinez FO, Gordon S. The M1 and M2 paradigm of macrophage activation: time for reassessment. F1000Prime Rep 2014; 6: 13.
    • (2014) F1000Prime Rep , vol.6 , pp. 13
    • Martinez, F.O.1    Gordon, S.2
  • 19
    • 84887444879 scopus 로고    scopus 로고
    • Microenvironmental regulation of tumor progression and metastasis
    • Quail DF, Joyce JA. Microenvironmental regulation of tumor progression and metastasis. Nat Med 2013; 19: 1423–37.
    • (2013) Nat Med , vol.19 , pp. 1423-1437
    • Quail, D.F.1    Joyce, J.A.2
  • 20
    • 41149164902 scopus 로고    scopus 로고
    • The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance
    • Allavena P, Sica A, Garlanda C, Mantovani A. The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance. Immunol Rev 2008; 222: 155–61.
    • (2008) Immunol Rev , vol.222 , pp. 155-161
    • Allavena, P.1    Sica, A.2    Garlanda, C.3    Mantovani, A.4
  • 21
    • 84904406680 scopus 로고    scopus 로고
    • Tumor-associated macrophages: From mechanisms to therapy
    • Noy R, Pollard JW. Tumor-associated macrophages: From mechanisms to therapy. Immunity 2014; 41: 49–61.
    • (2014) Immunity , vol.41 , pp. 49-61
    • Noy, R.1    Pollard, J.W.2
  • 22
    • 77954855351 scopus 로고    scopus 로고
    • Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma
    • Hasita H, Komohara Y, Okabe H et al. Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma. Cancer Sci 2010; 101: 1913–19.
    • (2010) Cancer Sci , vol.101 , pp. 1913-1919
    • Hasita, H.1    Komohara, Y.2    Okabe, H.3
  • 23
    • 84958057302 scopus 로고    scopus 로고
    • Cancer stem cells and tumor-associated macrophages: A roadmap for multitargeting strategies
    • Raggi C, Mousa HS, Correnti M, Sica A, Invernizzi P. Cancer stem cells and tumor-associated macrophages: A roadmap for multitargeting strategies. Oncogene 2016; 35: 671–82.
    • (2016) Oncogene , vol.35 , pp. 671-682
    • Raggi, C.1    Mousa, H.S.2    Correnti, M.3    Sica, A.4    Invernizzi, P.5
  • 24
    • 84908161000 scopus 로고    scopus 로고
    • Revisiting STAT3 signalling in cancer: New and unexpected biological functions
    • Yu H, Lee H, Herrmann A, Buettner R, Jove R. Revisiting STAT3 signalling in cancer: New and unexpected biological functions. Nat Rev Cancer 2014; 14: 736–46.
    • (2014) Nat Rev Cancer , vol.14 , pp. 736-746
    • Yu, H.1    Lee, H.2    Herrmann, A.3    Buettner, R.4    Jove, R.5
  • 25
    • 84870657385 scopus 로고    scopus 로고
    • Importance of direct macrophage-tumor cell interaction on progression of human glioma
    • Komohara Y, Horlad H, Ohnishi K et al. Importance of direct macrophage-tumor cell interaction on progression of human glioma. Cancer Sci 2012; 103: 2165–72.
    • (2012) Cancer Sci , vol.103 , pp. 2165-2172
    • Komohara, Y.1    Horlad, H.2    Ohnishi, K.3
  • 26
    • 78649982367 scopus 로고    scopus 로고
    • STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors
    • Lee H, Deng J, Kujawski M et al. STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors. Nat Med 2010; 16: 1421–8.
    • (2010) Nat Med , vol.16 , pp. 1421-1428
    • Lee, H.1    Deng, J.2    Kujawski, M.3
  • 27
    • 84934307169 scopus 로고    scopus 로고
    • CCL2-induced chemokine cascade promotes breast cancer metastasis by enhancing retention of metastasis-associated macrophages
    • Kitamura T, Qian BZ, Soong D et al. CCL2-induced chemokine cascade promotes breast cancer metastasis by enhancing retention of metastasis-associated macrophages. J Exp Med 2015; 212: 1043–59.
    • (2015) J Exp Med , vol.212 , pp. 1043-1059
    • Kitamura, T.1    Qian, B.Z.2    Soong, D.3
  • 28
    • 84861399789 scopus 로고    scopus 로고
    • S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites
    • Deng J, Liu Y, Lee H et al. S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites. Cancer Cell 2012; 21: 642–54.
    • (2012) Cancer Cell , vol.21 , pp. 642-654
    • Deng, J.1    Liu, Y.2    Lee, H.3
  • 29
    • 0029816609 scopus 로고    scopus 로고
    • Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma
    • Leek RD, Lewis CE, Whitehouse R, Greenall M, Clarke J, Harris AL. Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Res 1996; 56: 4625–9.
    • (1996) Cancer Res , vol.56 , pp. 4625-4629
    • Leek, R.D.1    Lewis, C.E.2    Whitehouse, R.3    Greenall, M.4    Clarke, J.5    Harris, A.L.6
  • 30
    • 0032933732 scopus 로고    scopus 로고
    • Clinical significance of thymidine phosphorylase as a marker of protumor monocytes in breast cancer
    • Toi M, Ueno T, Matsumoto H et al. Clinical significance of thymidine phosphorylase as a marker of protumor monocytes in breast cancer. Clin Cancer Res 1999; 5: 1131–7.
    • (1999) Clin Cancer Res , vol.5 , pp. 1131-1137
    • Toi, M.1    Ueno, T.2    Matsumoto, H.3
  • 31
    • 0036329210 scopus 로고    scopus 로고
    • Correlation between vascular endothelial growth factor, angiogenesis, and tumor-associated macrophages in invasive ductal breast carcinoma
    • Valković T, Dobrila F, Melato M, Sasso F, Rizzardi C, Jonjić N. Correlation between vascular endothelial growth factor, angiogenesis, and tumor-associated macrophages in invasive ductal breast carcinoma. Virchows Arch 2002; 440: 583–8.
    • (2002) Virchows Arch , vol.440 , pp. 583-588
    • Valković, T.1    Dobrila, F.2    Melato, M.3    Sasso, F.4    Rizzardi, C.5    Jonjić, N.6
  • 32
    • 33751098783 scopus 로고    scopus 로고
    • Microvessel density, VEGF expression, and tumor-associated macrophages in breast tumors: Correlations with prognostic parameters
    • Bolat F, Kayaselcuk F, Nursal TZ, Yagmurdur MC, Bal N, Demirhan B. Microvessel density, VEGF expression, and tumor-associated macrophages in breast tumors: Correlations with prognostic parameters. J Exp Clin Cancer Res 2006; 25: 365–72.
    • (2006) J Exp Clin Cancer Res , vol.25 , pp. 365-372
    • Bolat, F.1    Kayaselcuk, F.2    Nursal, T.Z.3    Yagmurdur, M.C.4    Bal, N.5    Demirhan, B.6
  • 33
    • 84907339661 scopus 로고    scopus 로고
    • High infiltration of tumor-associated macrophages in triple-negative breast cancer is associated with a higher risk of distant metastasis
    • Yuan ZY, Luo RZ, Peng RJ, Wang SS, Xue C. High infiltration of tumor-associated macrophages in triple-negative breast cancer is associated with a higher risk of distant metastasis. Onco Targets Ther 2014; 7: 1475–80.
    • (2014) Onco Targets Ther , vol.7 , pp. 1475-1480
    • Yuan, Z.Y.1    Luo, R.Z.2    Peng, R.J.3    Wang, S.S.4    Xue, C.5
  • 34
    • 84939459740 scopus 로고    scopus 로고
    • Human breast cancer cells educate macrophages toward the M2 activation status
    • Sousa S, Brion R, Lintunen M et al. Human breast cancer cells educate macrophages toward the M2 activation status. Breast Cancer Res 2015; 17: 101.
    • (2015) Breast Cancer Res , vol.17 , pp. 101
    • Sousa, S.1    Brion, R.2    Lintunen, M.3
  • 35
    • 84864828790 scopus 로고    scopus 로고
    • The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients
    • Medrek C, Pontén F, Jirström K, Leandersson K. The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients. BMC Cancer 2012; 12: 306.
    • (2012) BMC Cancer , vol.12 , pp. 306
    • Medrek, C.1    Pontén, F.2    Jirström, K.3    Leandersson, K.4
  • 36
    • 84876093272 scopus 로고    scopus 로고
    • In human invasive breast ductal carcinoma, tumor stromal macrophages and tumor nest macrophages have distinct relationships with clinicopathological parameters and tumor angiogenesis
    • Ch'ng ES, Tuan Sharif SE, Jaafar H. In human invasive breast ductal carcinoma, tumor stromal macrophages and tumor nest macrophages have distinct relationships with clinicopathological parameters and tumor angiogenesis. Virchows Arch 2013; 462: 257–67.
    • (2013) Virchows Arch , vol.462 , pp. 257-267
    • Ch'ng, E.S.1    Tuan Sharif, S.E.2    Jaafar, H.3
  • 37
    • 84862811913 scopus 로고    scopus 로고
    • Tumor-associated macrophages correlate with response to epidermal growth factor receptor-tyrosine kinase inhibitors in advanced non-small cell lung cancer
    • Chung FT, Lee KY, Wang CW et al. Tumor-associated macrophages correlate with response to epidermal growth factor receptor-tyrosine kinase inhibitors in advanced non-small cell lung cancer. Int J Cancer 2012; 131: E227–35.
    • (2012) Int J Cancer , vol.131 , pp. E227-E235
    • Chung, F.T.1    Lee, K.Y.2    Wang, C.W.3
  • 38
    • 77952416002 scopus 로고    scopus 로고
    • The number and microlocalization of tumor-associated immune cells are associated with patient's survival time in non-small cell lung cancer
    • Dai F, Liu L, Che G et al. The number and microlocalization of tumor-associated immune cells are associated with patient's survival time in non-small cell lung cancer. BMC Cancer 2010; 10: 220.
    • (2010) BMC Cancer , vol.10 , pp. 220
    • Dai, F.1    Liu, L.2    Che, G.3
  • 39
    • 58849166142 scopus 로고    scopus 로고
    • Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival
    • Ohri CM, Shikotra A, Green RH, Waller DA, Bradding P. Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival. Eur Respir J 2009; 33: 118–26.
    • (2009) Eur Respir J , vol.33 , pp. 118-126
    • Ohri, C.M.1    Shikotra, A.2    Green, R.H.3    Waller, D.A.4    Bradding, P.5
  • 40
    • 77953709449 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha expression in tumour islets confers a survival advantage in non-small cell lung cancer
    • Ohri CM, Shikotra A, Green RH, Waller DA, Bradding P. Tumour necrosis factor-alpha expression in tumour islets confers a survival advantage in non-small cell lung cancer. BMC Cancer 2010; 10: 323.
    • (2010) BMC Cancer , vol.10 , pp. 323
    • Ohri, C.M.1    Shikotra, A.2    Green, R.H.3    Waller, D.A.4    Bradding, P.5
  • 41
    • 77958187950 scopus 로고    scopus 로고
    • Stromal macrophage expressing CD204 is associated with tumor aggressiveness in lung adenocarcinoma
    • Ohtaki Y, Ishii G, Nagai K et al. Stromal macrophage expressing CD204 is associated with tumor aggressiveness in lung adenocarcinoma. J Thorac Oncol 2010; 5: 1507–15.
    • (2010) J Thorac Oncol , vol.5 , pp. 1507-1515
    • Ohtaki, Y.1    Ishii, G.2    Nagai, K.3
  • 42
    • 84870382348 scopus 로고    scopus 로고
    • Prognostic impact of CD204-positive macrophages in lung squamous cell carcinoma: Possible contribution of CD204-positive macrophages to the tumor-promoting microenvironment
    • Hirayama S, Ishii G, Nagai K et al. Prognostic impact of CD204-positive macrophages in lung squamous cell carcinoma: Possible contribution of CD204-positive macrophages to the tumor-promoting microenvironment. J Thorac Oncol 2012; 7: 1790–7.
    • (2012) J Thorac Oncol , vol.7 , pp. 1790-1797
    • Hirayama, S.1    Ishii, G.2    Nagai, K.3
  • 43
    • 84893412268 scopus 로고    scopus 로고
    • + cells predict postoperative recurrence in non-small-cell lung cancer patients
    • + cells predict postoperative recurrence in non-small-cell lung cancer patients. J Thorac Oncol 2014; 9: 179–88.
    • (2014) J Thorac Oncol , vol.9 , pp. 179-188
    • Maeda, R.1    Ishii, G.2    Neri, S.3
  • 44
    • 84892668814 scopus 로고    scopus 로고
    • Identification of prognostic immunophenotypic features in cancer stromal cells of high-grade neuroendocrine carcinomas of the lung
    • Takahashi A, Ishii G, Kinoshita T et al. Identification of prognostic immunophenotypic features in cancer stromal cells of high-grade neuroendocrine carcinomas of the lung. J Cancer Res Clin Oncol 2013; 139: 1869–78.
    • (2013) J Cancer Res Clin Oncol , vol.139 , pp. 1869-1878
    • Takahashi, A.1    Ishii, G.2    Kinoshita, T.3
  • 45
    • 45749137283 scopus 로고    scopus 로고
    • High expression of macrophage colony-stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma
    • Zhu XD, Zhang JB, Zhuang PY et al. High expression of macrophage colony-stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma. J Clin Oncol 2008; 26: 2707–16.
    • (2008) J Clin Oncol , vol.26 , pp. 2707-2716
    • Zhu, X.D.1    Zhang, J.B.2    Zhuang, P.Y.3
  • 46
    • 59049106749 scopus 로고    scopus 로고
    • High tumor-infiltrating macrophage density predicts poor prognosis in patients with primary hepatocellular carcinoma after resection
    • Ding T, Xu J, Wang F et al. High tumor-infiltrating macrophage density predicts poor prognosis in patients with primary hepatocellular carcinoma after resection. Hum Pathol 2009; 40: 381–9.
    • (2009) Hum Pathol , vol.40 , pp. 381-389
    • Ding, T.1    Xu, J.2    Wang, F.3
  • 47
    • 84875503384 scopus 로고    scopus 로고
    • The clinical significance of the CD163+ and CD68+ macrophages in patients with hepatocellular carcinoma
    • Kong LQ, Zhu XD, Xu HX et al. The clinical significance of the CD163+ and CD68+ macrophages in patients with hepatocellular carcinoma. PLoS One 2013; 8 :e59771
    • (2013) PLoS One , vol.8 , pp. e59771
    • Kong, L.Q.1    Zhu, X.D.2    Xu, H.X.3
  • 48
    • 59449106245 scopus 로고    scopus 로고
    • Tumor-infiltrating macrophages can predict favorable prognosis in hepatocellular carcinoma after resection
    • Li YW, Qiu SJ, Fan J et al. Tumor-infiltrating macrophages can predict favorable prognosis in hepatocellular carcinoma after resection. J Cancer Res Clin Oncol 2009; 135: 439–49.
    • (2009) J Cancer Res Clin Oncol , vol.135 , pp. 439-449
    • Li, Y.W.1    Qiu, S.J.2    Fan, J.3
  • 49
    • 84893816088 scopus 로고    scopus 로고
    • + M1-like macrophages promote motility of HCC cells via NF-κB/FAK pathway
    • + M1-like macrophages promote motility of HCC cells via NF-κB/FAK pathway. Cancer Lett 2014; 345: 91–9.
    • (2014) Cancer Lett , vol.345 , pp. 91-99
    • Wang, H.1    Wang, X.2    Li, X.3
  • 51
    • 84867504992 scopus 로고    scopus 로고
    • The distribution of macrophages with a M1 or M2 phenotype in relation to prognosis and the molecular characteristics of colorectal cancer
    • Edin S, Wikberg ML, Dahlin AM et al. The distribution of macrophages with a M1 or M2 phenotype in relation to prognosis and the molecular characteristics of colorectal cancer. PLoS One 2012; 7 :e47045
    • (2012) PLoS One , vol.7 , pp. e47045
    • Edin, S.1    Wikberg, M.L.2    Dahlin, A.M.3
  • 52
    • 77956362433 scopus 로고    scopus 로고
    • Intratumoral macrophage counts correlate with tumor progression in colorectal cancer
    • Kang JC, Chen JS, Lee CH, Chang JJ, Shieh YS. Intratumoral macrophage counts correlate with tumor progression in colorectal cancer. J Surg Oncol 2010; 102: 242–8.
    • (2010) J Surg Oncol , vol.102 , pp. 242-248
    • Kang, J.C.1    Chen, J.S.2    Lee, C.H.3    Chang, J.J.4    Shieh, Y.S.5
  • 53
    • 0030768642 scopus 로고    scopus 로고
    • Expression of costimulatory molecules B7-1 and B7-2 by macrophages along invasive margin of colon cancer: A possible antitumor immunity?
    • Ohtani H, Naito Y, Saito K, Nagura H. Expression of costimulatory molecules B7-1 and B7-2 by macrophages along invasive margin of colon cancer: A possible antitumor immunity? Lab Invest 1997; 77: 231–41.
    • (1997) Lab Invest , vol.77 , pp. 231-241
    • Ohtani, H.1    Naito, Y.2    Saito, K.3    Nagura, H.4
  • 54
    • 70349259469 scopus 로고    scopus 로고
    • Expression of the macrophage antigen CD163 in rectal cancer cells is associated with early local recurrence and reduced survival time
    • Shabo I, Olsson H, Sun XF, Svanvik J. Expression of the macrophage antigen CD163 in rectal cancer cells is associated with early local recurrence and reduced survival time. Int J Cancer 2009; 125: 1826–31.
    • (2009) Int J Cancer , vol.125 , pp. 1826-1831
    • Shabo, I.1    Olsson, H.2    Sun, X.F.3    Svanvik, J.4
  • 55
    • 84899630144 scopus 로고    scopus 로고
    • Inflammation-related factors predicting prognosis of gastric cancer
    • Chang WJ, Du Y, Zhao X, Ma LY, Cao GW. Inflammation-related factors predicting prognosis of gastric cancer. World J Gastroenterol 2014; 20: 4586–96.
    • (2014) World J Gastroenterol , vol.20 , pp. 4586-4596
    • Chang, W.J.1    Du, Y.2    Zhao, X.3    Ma, L.Y.4    Cao, G.W.5
  • 56
    • 0344874045 scopus 로고    scopus 로고
    • Tumor-associated macrophage (TAM) infiltration in gastric cancer
    • Ishigami S, Natsugoe S, Tokuda K et al. Tumor-associated macrophage (TAM) infiltration in gastric cancer. Anticancer Res 2003; 23: 4079–83.
    • (2003) Anticancer Res , vol.23 , pp. 4079-4083
    • Ishigami, S.1    Natsugoe, S.2    Tokuda, K.3
  • 57
    • 84891153305 scopus 로고    scopus 로고
    • The role of macrophages polarization in predicting prognosis of radically resected gastric cancer patients
    • Pantano F, Berti P, Guida FM et al. The role of macrophages polarization in predicting prognosis of radically resected gastric cancer patients. J Cell Mol Med 2013; 17: 1415–21.
    • (2013) J Cell Mol Med , vol.17 , pp. 1415-1421
    • Pantano, F.1    Berti, P.2    Guida, F.M.3
  • 58
    • 84926373271 scopus 로고    scopus 로고
    • The significance of the co-existence of osteopontin and tumor-associated macrophages in gastric cancer progression
    • Lin CN, Wang CJ, Chao YJ, Lai MD, Shan YS. The significance of the co-existence of osteopontin and tumor-associated macrophages in gastric cancer progression. BMC Cancer 2015; 15: 128.
    • (2015) BMC Cancer , vol.15 , pp. 128
    • Lin, C.N.1    Wang, C.J.2    Chao, Y.J.3    Lai, M.D.4    Shan, Y.S.5
  • 59
    • 84864832834 scopus 로고    scopus 로고
    • The role of stroma in pancreatic cancer: Diagnostic and therapeutic implications
    • Erkan M, Hausmann S, Michalski CW et al. The role of stroma in pancreatic cancer: Diagnostic and therapeutic implications. Nat Rev Gastroenterol Hepatol 2012; 9: 454–67.
    • (2012) Nat Rev Gastroenterol Hepatol , vol.9 , pp. 454-467
    • Erkan, M.1    Hausmann, S.2    Michalski, C.W.3
  • 60
    • 79954600458 scopus 로고    scopus 로고
    • Significance of M2-polarized tumor-associated macrophage in pancreatic cancer
    • Kurahara H, Shinchi H, Mataki Y et al. Significance of M2-polarized tumor-associated macrophage in pancreatic cancer. J Surg Res 2011; 167: e211–19.
    • (2011) J Surg Res , vol.167 , pp. e211-e219
    • Kurahara, H.1    Shinchi, H.2    Mataki, Y.3
  • 61
    • 84868212819 scopus 로고    scopus 로고
    • Impact of tumor-associated macrophages on invasive ductal carcinoma of the pancreas head
    • Yoshikawa K, Mitsunaga S, Kinoshita T et al. Impact of tumor-associated macrophages on invasive ductal carcinoma of the pancreas head. Cancer Sci 2012; 103: 2012–20.
    • (2012) Cancer Sci , vol.103 , pp. 2012-2020
    • Yoshikawa, K.1    Mitsunaga, S.2    Kinoshita, T.3
  • 62
    • 84906791750 scopus 로고    scopus 로고
    • Coexpression of CD44-positive/CD133-positive cancer stem cells and CD204-positive tumor-associated macrophages is a predictor of survival in pancreatic ductal adenocarcinoma
    • Hou YC, Chao YJ, Tung HL, Wang HC, Shan YS. Coexpression of CD44-positive/CD133-positive cancer stem cells and CD204-positive tumor-associated macrophages is a predictor of survival in pancreatic ductal adenocarcinoma. Cancer 2014; 120: 2766–77.
    • (2014) Cancer , vol.120 , pp. 2766-2777
    • Hou, Y.C.1    Chao, Y.J.2    Tung, H.L.3    Wang, H.C.4    Shan, Y.S.5
  • 63
    • 68749087029 scopus 로고    scopus 로고
    • Characterization of the intra-prostatic immune cell infiltration in androgen-deprived prostate cancer patients
    • Gannon PO, Poisson AO, Delvoye N, Lapointe R, Mes-Masson AM, Saad F. Characterization of the intra-prostatic immune cell infiltration in androgen-deprived prostate cancer patients. J Immunol Methods 2009; 348: 9–17.
    • (2009) J Immunol Methods , vol.348 , pp. 9-17
    • Gannon, P.O.1    Poisson, A.O.2    Delvoye, N.3    Lapointe, R.4    Mes-Masson, A.M.5    Saad, F.6
  • 64
    • 79957822818 scopus 로고    scopus 로고
    • Infiltration of tumour-associated macrophages in prostate biopsy specimens is predictive of disease progression after hormonal therapy for prostate cancer
    • Nonomura N, Takayama H, Nakayama M et al. Infiltration of tumour-associated macrophages in prostate biopsy specimens is predictive of disease progression after hormonal therapy for prostate cancer. BJU Int 2011; 107: 1918–22.
    • (2011) BJU Int , vol.107 , pp. 1918-1922
    • Nonomura, N.1    Takayama, H.2    Nakayama, M.3
  • 65
    • 59249099124 scopus 로고    scopus 로고
    • Decreased immunostaining for macrophage scavenger receptor is associated with poor prognosis of prostate cancer
    • Takayama H, Nonomura N, Nishimura K et al. Decreased immunostaining for macrophage scavenger receptor is associated with poor prognosis of prostate cancer. BJU Int 2009; 103: 470–4.
    • (2009) BJU Int , vol.103 , pp. 470-474
    • Takayama, H.1    Nonomura, N.2    Nishimura, K.3
  • 66
    • 84897499540 scopus 로고    scopus 로고
    • Association between tumor-associated macrophage infiltration, high grade prostate cancer, and biochemical recurrence after radical prostatectomy
    • Gollapudi K, Galet C, Grogan T et al. Association between tumor-associated macrophage infiltration, high grade prostate cancer, and biochemical recurrence after radical prostatectomy. Am J Cancer Res 2013; 3: 523–9.
    • (2013) Am J Cancer Res , vol.3 , pp. 523-529
    • Gollapudi, K.1    Galet, C.2    Grogan, T.3
  • 67
    • 84872272400 scopus 로고    scopus 로고
    • Immunohistochemical analysis of inflammatory cells in benign and precancerous lesions and carcinoma of the prostate
    • Fujii T, Shimada K, Asai O et al. Immunohistochemical analysis of inflammatory cells in benign and precancerous lesions and carcinoma of the prostate. Pathobiology 2013; 80: 119–26.
    • (2013) Pathobiology , vol.80 , pp. 119-126
    • Fujii, T.1    Shimada, K.2    Asai, O.3
  • 68
    • 0027960554 scopus 로고
    • T lymphocytes, CD68-positive cells and vascularisation in thyroid carcinomas
    • Herrmann G, Schumm-Draeger PM, Müller C et al. T lymphocytes, CD68-positive cells and vascularisation in thyroid carcinomas. J Cancer Res Clin Oncol 1994; 120: 651–6.
    • (1994) J Cancer Res Clin Oncol , vol.120 , pp. 651-656
    • Herrmann, G.1    Schumm-Draeger, P.M.2    Müller, C.3
  • 69
    • 56649101166 scopus 로고    scopus 로고
    • Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer
    • Ryder M, Ghossein RA, Ricarte-Filho JC, Knauf JA, Fagin JA. Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer. Endocr Relat Cancer 2008; 15: 1069–74.
    • (2008) Endocr Relat Cancer , vol.15 , pp. 1069-1074
    • Ryder, M.1    Ghossein, R.A.2    Ricarte-Filho, J.C.3    Knauf, J.A.4    Fagin, J.A.5
  • 70
    • 84865591281 scopus 로고    scopus 로고
    • Density of tumor-associated macrophages correlates with lymph node metastasis in papillary thyroid carcinoma
    • Qing W, Fang WY, Ye L et al. Density of tumor-associated macrophages correlates with lymph node metastasis in papillary thyroid carcinoma. Thyroid 2012; 22: 905–10.
    • (2012) Thyroid , vol.22 , pp. 905-910
    • Qing, W.1    Fang, W.Y.2    Ye, L.3
  • 71
    • 84869063600 scopus 로고    scopus 로고
    • Infiltration of a mixture of immune cells may be related to good prognosis in patients with differentiated thyroid carcinoma
    • Cunha LL, Morari EC, Guihen AC et al. Infiltration of a mixture of immune cells may be related to good prognosis in patients with differentiated thyroid carcinoma. Clin Endocrinol (Oxf) 2012; 77: 918–25.
    • (2012) Clin Endocrinol (Oxf) , vol.77 , pp. 918-925
    • Cunha, L.L.1    Morari, E.C.2    Guihen, A.C.3
  • 72
    • 77955736266 scopus 로고    scopus 로고
    • Tissue invasive macrophage density is correlated with prognosis in cholangiocarcinoma
    • Subimerb C, Pinlaor S, Khuntikeo N et al. Tissue invasive macrophage density is correlated with prognosis in cholangiocarcinoma. Mol Med Rep 2010; 3: 597–605.
    • (2010) Mol Med Rep , vol.3 , pp. 597-605
    • Subimerb, C.1    Pinlaor, S.2    Khuntikeo, N.3
  • 73
    • 77955736844 scopus 로고    scopus 로고
    • + monocyte levels predict tissue invasive character of cholangiocarcinoma
    • + monocyte levels predict tissue invasive character of cholangiocarcinoma. Clin Exp Immunol 2010; 161: 471–79.
    • (2010) Clin Exp Immunol , vol.161 , pp. 471-479
    • Subimerb, C.1    Pinlaor, S.2    Lulitanond, V.3
  • 74
    • 84928610658 scopus 로고    scopus 로고
    • Quantitative changes in tumor-associated M2 macrophages characterize cholangiocarcinoma and their association with metastasis
    • Thanee M, Loilome W, Techasen A et al. Quantitative changes in tumor-associated M2 macrophages characterize cholangiocarcinoma and their association with metastasis. Asian Pac J Cancer Prev 2015; 16: 3043–50.
    • (2015) Asian Pac J Cancer Prev , vol.16 , pp. 3043-3050
    • Thanee, M.1    Loilome, W.2    Techasen, A.3
  • 75
    • 84874100938 scopus 로고    scopus 로고
    • Cytokines released from activated human macrophages induce epithelial mesenchymal transition markers of cholangiocarcinoma cells
    • Techasen A, Loilome W, Namwat N, Dokduang H, Jongthawin J, Yongvanit P. Cytokines released from activated human macrophages induce epithelial mesenchymal transition markers of cholangiocarcinoma cells. Asian Pac J Cancer Prev Suppl 2012; 13: 115–8.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 115-118
    • Techasen, A.1    Loilome, W.2    Namwat, N.3    Dokduang, H.4    Jongthawin, J.5    Yongvanit, P.6
  • 76
    • 84890352055 scopus 로고    scopus 로고
    • Emerging role of tumor-associated macrophages as therapeutic targets in patients with metastatic renal cell carcinoma
    • Santoni M, Massari F, Amantini C et al. Emerging role of tumor-associated macrophages as therapeutic targets in patients with metastatic renal cell carcinoma. Cancer Immunol Immunother 2013; 62: 1757–68.
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 1757-1768
    • Santoni, M.1    Massari, F.2    Amantini, C.3
  • 77
    • 70349733201 scopus 로고    scopus 로고
    • Angiogenesis in renal cell carcinoma: The role of tumor-associated macrophages
    • Toge H, Inagaki T, Kojimoto Y, Shinka T, Hara I. Angiogenesis in renal cell carcinoma: The role of tumor-associated macrophages. Int J Urol 2009; 16: 801–7.
    • (2009) Int J Urol , vol.16 , pp. 801-807
    • Toge, H.1    Inagaki, T.2    Kojimoto, Y.3    Shinka, T.4    Hara, I.5
  • 78
    • 84886945385 scopus 로고    scopus 로고
    • Tumor-associated macrophages subvert T-cell function and correlate with reduced survival in clear cell renal cell carcinoma
    • Dannenmann SR, Thielicke J, Stöckli M et al. Tumor-associated macrophages subvert T-cell function and correlate with reduced survival in clear cell renal cell carcinoma. Oncoimmunology 2013; 2 :e23562
    • (2013) Oncoimmunology , vol.2 , pp. e23562
    • Dannenmann, S.R.1    Thielicke, J.2    Stöckli, M.3
  • 79
    • 79959228665 scopus 로고    scopus 로고
    • Macrophage infiltration and its prognostic relevance in clear cell renal cell carcinoma
    • Komohara Y, Hasita H, Ohnishi K et al. Macrophage infiltration and its prognostic relevance in clear cell renal cell carcinoma. Cancer Sci 2011; 102: 1424–31.
    • (2011) Cancer Sci , vol.102 , pp. 1424-1431
    • Komohara, Y.1    Hasita, H.2    Ohnishi, K.3
  • 80
    • 84906226080 scopus 로고    scopus 로고
    • Prognostic value of diametrically polarized tumor-associated macrophages in renal cell carcinoma
    • Xu L, Zhu Y, Chen L et al. Prognostic value of diametrically polarized tumor-associated macrophages in renal cell carcinoma. Ann Surg Oncol 2014; 21: 3142–50.
    • (2014) Ann Surg Oncol , vol.21 , pp. 3142-3150
    • Xu, L.1    Zhu, Y.2    Chen, L.3
  • 81
    • 84961994266 scopus 로고    scopus 로고
    • The coordinated actions of TIM-3 on cancer and myeloid cells in the regulation of tumorigenicity and clinical prognosis in clear cell renal cell carcinomas
    • Komohara Y, Morita T, Annan DA et al. The coordinated actions of TIM-3 on cancer and myeloid cells in the regulation of tumorigenicity and clinical prognosis in clear cell renal cell carcinomas. Cancer Immunol Res 2015; 3: 999–1007.
    • (2015) Cancer Immunol Res , vol.3 , pp. 999-1007
    • Komohara, Y.1    Morita, T.2    Annan, D.A.3
  • 82
    • 0033938697 scopus 로고    scopus 로고
    • Prognostic value of tumor-associated macrophage count in human bladder cancer
    • Hanada T, Nakagawa M, Emoto A, Nomura T, Nasu N, Nomura Y. Prognostic value of tumor-associated macrophage count in human bladder cancer. Int J Urol 2000; 7: 263–9.
    • (2000) Int J Urol , vol.7 , pp. 263-269
    • Hanada, T.1    Nakagawa, M.2    Emoto, A.3    Nomura, T.4    Nasu, N.5    Nomura, Y.6
  • 83
    • 61349181401 scopus 로고    scopus 로고
    • Overexpression of cyclooxygenase-2 in urothelial carcinoma in conjunction with tumor-associated-macrophage infiltration, hypoxia-inducible factor-1α expression, and tumor angiogenesis
    • Chen WT, Hung WC, Kang WY et al. Overexpression of cyclooxygenase-2 in urothelial carcinoma in conjunction with tumor-associated-macrophage infiltration, hypoxia-inducible factor-1α expression, and tumor angiogenesis. APMIS 2009; 117: 176–84.
    • (2009) APMIS , vol.117 , pp. 176-184
    • Chen, W.T.1    Hung, W.C.2    Kang, W.Y.3
  • 84
    • 65049091771 scopus 로고    scopus 로고
    • Bladder tumor infiltrating mature dendritic cells and macrophages as predictors of response to bacillus Calmette-Guérin immunotherapy
    • Ayari C, LaRue H, Hovington H et al. Bladder tumor infiltrating mature dendritic cells and macrophages as predictors of response to bacillus Calmette-Guérin immunotherapy. Eur Urol 2009; 55: 1386–95.
    • (2009) Eur Urol , vol.55 , pp. 1386-1395
    • Ayari, C.1    LaRue, H.2    Hovington, H.3
  • 85
    • 61949486981 scopus 로고    scopus 로고
    • Increased infiltration of tumor associated macrophages is associated with poor prognosis of bladder carcinoma in situ after intravesical bacillus Calmette-Guerin instillation
    • Takayama H, Nishimura K, Tsujimura A et al. Increased infiltration of tumor associated macrophages is associated with poor prognosis of bladder carcinoma in situ after intravesical bacillus Calmette-Guerin instillation. J Urol 2009; 181: 1894–900.
    • (2009) J Urol , vol.181 , pp. 1894-1900
    • Takayama, H.1    Nishimura, K.2    Tsujimura, A.3
  • 86
    • 84940192893 scopus 로고    scopus 로고
    • + tumor-infiltrating macrophage density predicts a poor prognosis in patients with urothelial cell carcinoma of the bladder
    • + tumor-infiltrating macrophage density predicts a poor prognosis in patients with urothelial cell carcinoma of the bladder. Oncotarget 2015; 6: 20204–14.
    • (2015) Oncotarget , vol.6 , pp. 20204-20214
    • Wang, B.1    Liu, H.2    Dong, X.3
  • 87
    • 0033595619 scopus 로고    scopus 로고
    • Significance of tumour-associated macrophages, vascular endothelial growth factor and thrombospondin-1 expression for tumour angiogenesis and prognosis in endometrial carcinomas
    • Salvesen HB, Akslen LA. Significance of tumour-associated macrophages, vascular endothelial growth factor and thrombospondin-1 expression for tumour angiogenesis and prognosis in endometrial carcinomas. Int J Cancer 1999; 84: 538–43.
    • (1999) Int J Cancer , vol.84 , pp. 538-543
    • Salvesen, H.B.1    Akslen, L.A.2
  • 88
    • 40949090491 scopus 로고    scopus 로고
    • Tumor-associated macrophages correlate with vascular space invasion and myometrial invasion in endometrial carcinoma
    • Soeda S, Nakamura N, Ozeki T et al. Tumor-associated macrophages correlate with vascular space invasion and myometrial invasion in endometrial carcinoma. Gynecol Oncol 2008; 109: 122–8.
    • (2008) Gynecol Oncol , vol.109 , pp. 122-128
    • Soeda, S.1    Nakamura, N.2    Ozeki, T.3
  • 89
    • 0034491645 scopus 로고    scopus 로고
    • Macrophage infiltration and angiogenesis in endometrial cancer
    • Hashimoto I, Kodama J, Seki N et al. Macrophage infiltration and angiogenesis in endometrial cancer. Anticancer Res 2000; 20: 4853–6.
    • (2000) Anticancer Res , vol.20 , pp. 4853-4856
    • Hashimoto, I.1    Kodama, J.2    Seki, N.3
  • 90
    • 78049527432 scopus 로고    scopus 로고
    • Myometrial invasion and lymph node metastasis in endometrioid carcinomas: Tumor-associated macrophages, microvessel density, and HIF1A have a crucial role
    • Espinosa I, José Carnicer M, Catasus L et al. Myometrial invasion and lymph node metastasis in endometrioid carcinomas: Tumor-associated macrophages, microvessel density, and HIF1A have a crucial role. Am J Surg Pathol 2010; 34: 1708–14.
    • (2010) Am J Surg Pathol , vol.34 , pp. 1708-1714
    • Espinosa, I.1    José Carnicer, M.2    Catasus, L.3
  • 91
    • 77957028841 scopus 로고    scopus 로고
    • Involvement of M2-polarized macrophages in the ascites from advanced epithelial ovarian carcinoma in tumor progression via Stat3 activation
    • Takaishi K, Komohara Y, Tashiro H et al. Involvement of M2-polarized macrophages in the ascites from advanced epithelial ovarian carcinoma in tumor progression via Stat3 activation. Cancer Sci 2010; 101: 2128–36.
    • (2010) Cancer Sci , vol.101 , pp. 2128-2136
    • Takaishi, K.1    Komohara, Y.2    Tashiro, H.3
  • 92
    • 84877150482 scopus 로고    scopus 로고
    • Expression of M2-polarized macrophages is associated with poor prognosis for advanced epithelial ovarian cancer
    • Lan C, Huang X, Lin S et al. Expression of M2-polarized macrophages is associated with poor prognosis for advanced epithelial ovarian cancer. Technol Cancer Res Treat 2013; 12: 259–67.
    • (2013) Technol Cancer Res Treat , vol.12 , pp. 259-267
    • Lan, C.1    Huang, X.2    Lin, S.3
  • 93
    • 65349163532 scopus 로고    scopus 로고
    • Detection of M2 macrophages and colony-stimulating factor 1 expression in serous and mucinous ovarian epithelial tumors
    • Kawamura K, Komohara Y, Takaishi K, Katabuchi H, Takeya M. Detection of M2 macrophages and colony-stimulating factor 1 expression in serous and mucinous ovarian epithelial tumors. Pathol Int 2009; 59: 300–5.
    • (2009) Pathol Int , vol.59 , pp. 300-305
    • Kawamura, K.1    Komohara, Y.2    Takaishi, K.3    Katabuchi, H.4    Takeya, M.5
  • 94
    • 84893655060 scopus 로고    scopus 로고
    • A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients
    • Zhang M, He Y, Sun X et al. A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients. J Ovarian Res 2014; 7: 19.
    • (2014) J Ovarian Res , vol.7 , pp. 19
    • Zhang, M.1    He, Y.2    Sun, X.3
  • 95
    • 84856477657 scopus 로고    scopus 로고
    • Immunosuppressive tumor microenvironment in cervical cancer patients
    • Piersma SJ. Immunosuppressive tumor microenvironment in cervical cancer patients. Cancer Microenviron 2011; 4: 361–75.
    • (2011) Cancer Microenviron , vol.4 , pp. 361-375
    • Piersma, S.J.1
  • 96
    • 33846696330 scopus 로고    scopus 로고
    • Role of tumor-derived proinflammatory cytokines GM-CSF, TNF-α, and IL-12 in the migration and differentiation of antigen-presenting cells in cervical carcinoma
    • Zijlmans HJ, Fleuren GJ, Baelde HJ, Eilers PH, Kenter GG, Gorter A. Role of tumor-derived proinflammatory cytokines GM-CSF, TNF-α, and IL-12 in the migration and differentiation of antigen-presenting cells in cervical carcinoma. Cancer 2007; 109: 556–65.
    • (2007) Cancer , vol.109 , pp. 556-565
    • Zijlmans, H.J.1    Fleuren, G.J.2    Baelde, H.J.3    Eilers, P.H.4    Kenter, G.G.5    Gorter, A.6
  • 97
    • 33947330625 scopus 로고    scopus 로고
    • Macrophages, inflammation and risk of cervical intraepithelial neoplasia (CIN) progression—Clinicopathological correlation
    • Hammes LS, Tekmal RR, Naud P et al. Macrophages, inflammation and risk of cervical intraepithelial neoplasia (CIN) progression—Clinicopathological correlation. Gynecol Oncol 2007; 105: 157–65.
    • (2007) Gynecol Oncol , vol.105 , pp. 157-165
    • Hammes, L.S.1    Tekmal, R.R.2    Naud, P.3
  • 98
    • 84922061259 scopus 로고    scopus 로고
    • Tumor-associated macrophages induce lymphangiogenesis in cervical cancer via interaction with tumor cells
    • Ding H, Cai J, Mao M et al. Tumor-associated macrophages induce lymphangiogenesis in cervical cancer via interaction with tumor cells. APMIS 2014; 122: 1059–69.
    • (2014) APMIS , vol.122 , pp. 1059-1069
    • Ding, H.1    Cai, J.2    Mao, M.3
  • 99
    • 84946222780 scopus 로고    scopus 로고
    • Polarisation of tumor-associated macrophages toward M2 phenotype correlates with poor response to chemoradiation and reduced survival in patients with locally advanced cervical cancer
    • Petrillo M, Zannoni GF, Martinelli E et al. Polarisation of tumor-associated macrophages toward M2 phenotype correlates with poor response to chemoradiation and reduced survival in patients with locally advanced cervical cancer. PLoS One 2015; 10 :e0136654
    • (2015) PLoS One , vol.10 , pp. e0136654
    • Petrillo, M.1    Zannoni, G.F.2    Martinelli, E.3
  • 100
    • 84893863200 scopus 로고    scopus 로고
    • Macrophage polarisation: An immunohistochemical approach for identifying M1 and M2 macrophages
    • Barros MH, Hauck F, Dreyer JH, Kempkes B, Niedobitek G. Macrophage polarisation: An immunohistochemical approach for identifying M1 and M2 macrophages. PLoS One 2013; 8 :e80908
    • (2013) PLoS One , vol.8 , pp. e80908
    • Barros, M.H.1    Hauck, F.2    Dreyer, J.H.3    Kempkes, B.4    Niedobitek, G.5
  • 101
    • 34147128107 scopus 로고    scopus 로고
    • Tumor-associated macrophages and CD3-ζ expression of tumor-infiltrating lymphocytes in human esophageal squamous-cell carcinoma
    • Guo SJ, Lin DM, Li J et al. Tumor-associated macrophages and CD3-ζ expression of tumor-infiltrating lymphocytes in human esophageal squamous-cell carcinoma. Dis Esophagus 2007; 20: 107–16.
    • (2007) Dis Esophagus , vol.20 , pp. 107-116
    • Guo, S.J.1    Lin, D.M.2    Li, J.3
  • 102
    • 84881099843 scopus 로고    scopus 로고
    • Tumor associated macrophage expressing CD204 is associated with tumor aggressiveness of esophageal squamous cell carcinoma
    • Shigeoka M, Urakawa N, Nakamura T et al. Tumor associated macrophage expressing CD204 is associated with tumor aggressiveness of esophageal squamous cell carcinoma. Cancer Sci 2013; 104: 1112–9.
    • (2013) Cancer Sci , vol.104 , pp. 1112-1119
    • Shigeoka, M.1    Urakawa, N.2    Nakamura, T.3
  • 103
    • 84940794314 scopus 로고    scopus 로고
    • Macrophage subtype predicts lymph node metastasis in oesophageal adenocarcinoma and promotes cancer cell invasion in vitro
    • Cao W, Peters JH, Nieman D, Sharma M, Watson T, Yu J. Macrophage subtype predicts lymph node metastasis in oesophageal adenocarcinoma and promotes cancer cell invasion in vitro. Br J Cancer 2015; 113: 738–46.
    • (2015) Br J Cancer , vol.113 , pp. 738-746
    • Cao, W.1    Peters, J.H.2    Nieman, D.3    Sharma, M.4    Watson, T.5    Yu, J.6
  • 104
    • 50249144131 scopus 로고    scopus 로고
    • Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas
    • Komohara Y, Ohnishi K, Kuratsu J, Takeya M. Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas. J Pathol 2008; 216: 15–24.
    • (2008) J Pathol , vol.216 , pp. 15-24
    • Komohara, Y.1    Ohnishi, K.2    Kuratsu, J.3    Takeya, M.4
  • 105
    • 0030951515 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 expression and macrophage infiltration in gliomas
    • Leung SY, Wong MP, Chung LP, Chan AS, Yuen ST. Monocyte chemoattractant protein-1 expression and macrophage infiltration in gliomas. Acta Neuropathol 1997; 93: 518–27.
    • (1997) Acta Neuropathol , vol.93 , pp. 518-527
    • Leung, S.Y.1    Wong, M.P.2    Chung, L.P.3    Chan, A.S.4    Yuen, S.T.5
  • 106
    • 84878811407 scopus 로고    scopus 로고
    • Distinct roles of CSF family cytokines in macrophage infiltration and activation in glioma progression and injury response
    • Sielska M, Przanowski P, Wylot B et al. Distinct roles of CSF family cytokines in macrophage infiltration and activation in glioma progression and injury response. J Pathol 2013; 230: 310–21.
    • (2013) J Pathol , vol.230 , pp. 310-321
    • Sielska, M.1    Przanowski, P.2    Wylot, B.3
  • 107
    • 0024538514 scopus 로고
    • Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants
    • Yoshimura T, Robinson EA, Tanaka S, Appella E, Kuratsu J, Leonard EJ. Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants. J Exp Med 1989; 169: 1449–59.
    • (1989) J Exp Med , vol.169 , pp. 1449-1459
    • Yoshimura, T.1    Robinson, E.A.2    Tanaka, S.3    Appella, E.4    Kuratsu, J.5    Leonard, E.J.6
  • 108
    • 0026552605 scopus 로고
    • Turnover of resident microglia in the normal adult mouse brain
    • Lawson LJ, Perry VH, Gordon S. Turnover of resident microglia in the normal adult mouse brain. Neuroscience 1992; 48: 405–15.
    • (1992) Neuroscience , vol.48 , pp. 405-415
    • Lawson, L.J.1    Perry, V.H.2    Gordon, S.3
  • 109
    • 0034860171 scopus 로고    scopus 로고
    • Angiogenic effect of thymidine phosphorylase on macrophages in glioblastoma multiforme
    • Hirano H, Tanioka K, Yokoyama S, Akiyama S, Kuratsu J. Angiogenic effect of thymidine phosphorylase on macrophages in glioblastoma multiforme. J Neurosurg 2001; 95: 89–95.
    • (2001) J Neurosurg , vol.95 , pp. 89-95
    • Hirano, H.1    Tanioka, K.2    Yokoyama, S.3    Akiyama, S.4    Kuratsu, J.5
  • 110
    • 33645962543 scopus 로고    scopus 로고
    • Expression and localization of VEGF-C and VEGFR-3 in glioblastomas and haemangioblastomas
    • Jenny B, Harrison JA, Baetens D et al. Expression and localization of VEGF-C and VEGFR-3 in glioblastomas and haemangioblastomas. J Pathol 2006; 209: 34–43.
    • (2006) J Pathol , vol.209 , pp. 34-43
    • Jenny, B.1    Harrison, J.A.2    Baetens, D.3
  • 111
    • 84865614917 scopus 로고    scopus 로고
    • Microglial stimulation of glioblastoma invasion involves epidermal growth factor receptor (EGFR) and colony stimulating factor 1 receptor (CSF-1R) signaling
    • Coniglio SJ, Eugenin E, Dobrenis K et al. Microglial stimulation of glioblastoma invasion involves epidermal growth factor receptor (EGFR) and colony stimulating factor 1 receptor (CSF-1R) signaling. Mol Med 2012; 18: 519–27.
    • (2012) Mol Med , vol.18 , pp. 519-527
    • Coniglio, S.J.1    Eugenin, E.2    Dobrenis, K.3
  • 112
    • 0029781336 scopus 로고    scopus 로고
    • Distribution and characterization of microglia/macrophages in human brain tumors
    • Roggendorf W, Strupp S, Paulus W. Distribution and characterization of microglia/macrophages in human brain tumors. Acta Neuropathol 1996; 92: 288–93.
    • (1996) Acta Neuropathol , vol.92 , pp. 288-293
    • Roggendorf, W.1    Strupp, S.2    Paulus, W.3
  • 113
    • 0023914933 scopus 로고
    • Inflammatory cell infiltrates in human melanoma at different stages of tumor progression
    • Bröcker EB, Zwadlo G, Holzmann B et al. Inflammatory cell infiltrates in human melanoma at different stages of tumor progression. Int J Cancer 1988; 41: 562–7.
    • (1988) Int J Cancer , vol.41 , pp. 562-567
    • Bröcker, E.B.1    Zwadlo, G.2    Holzmann, B.3
  • 114
    • 27644590410 scopus 로고    scopus 로고
    • Tumour-associated macrophage infiltration, neovascularization and aggressiveness in malignant melanoma: Role of monocyte chemotactic protein-1 and vascular endothelial growth factor-A
    • Varney ML, Johansson SL, Singh RK. Tumour-associated macrophage infiltration, neovascularization and aggressiveness in malignant melanoma: Role of monocyte chemotactic protein-1 and vascular endothelial growth factor-A. Melanoma Res 2005; 15: 417–25.
    • (2005) Melanoma Res , vol.15 , pp. 417-425
    • Varney, M.L.1    Johansson, S.L.2    Singh, R.K.3
  • 115
    • 70249084906 scopus 로고    scopus 로고
    • Macrophage markers in serum and tumor have prognostic impact in American Joint Committee on Cancer stage I/II melanoma
    • Jensen TO, Schmidt H, Møller HJ et al. Macrophage markers in serum and tumor have prognostic impact in American Joint Committee on Cancer stage I/II melanoma. J Clin Oncol 2009; 27: 3330–7.
    • (2009) J Clin Oncol , vol.27 , pp. 3330-3337
    • Jensen, T.O.1    Schmidt, H.2    Møller, H.J.3
  • 116
    • 77957731938 scopus 로고    scopus 로고
    • Clinicopathological implications of tumour-associated macrophages and vascularization in sinonasal melanoma
    • Shi L, Lei D, Ma C et al. Clinicopathological implications of tumour-associated macrophages and vascularization in sinonasal melanoma. J Int Med Res 2010; 38: 1276–86.
    • (2010) J Int Med Res , vol.38 , pp. 1276-1286
    • Shi, L.1    Lei, D.2    Ma, C.3
  • 117
    • 79953276590 scopus 로고    scopus 로고
    • Detection of M2-macrophages in uveal melanoma and relation with survival
    • Bronkhorst IH, Ly LV, Jordanova ES et al. Detection of M2-macrophages in uveal melanoma and relation with survival. Invest Ophthalmol Vis Sci 2011; 52: 643–50.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 643-650
    • Bronkhorst, I.H.1    Ly, L.V.2    Jordanova, E.S.3
  • 118
    • 0015896953 scopus 로고
    • Analysis of the Rye classification of Hodgkin's disease. The prognostic significance of cellular composition
    • Coppleson LW, Rappaport H, Strum SB, Rose J. Analysis of the Rye classification of Hodgkin's disease. The prognostic significance of cellular composition. J Natl Cancer Inst 1973; 51: 379–90.
    • (1973) J Natl Cancer Inst , vol.51 , pp. 379-390
    • Coppleson, L.W.1    Rappaport, H.2    Strum, S.B.3    Rose, J.4
  • 119
    • 77949345555 scopus 로고    scopus 로고
    • Tumor-associated macrophages and survival in classic Hodgkin's lymphoma
    • Steidl C, Lee T, Shah SP et al. Tumor-associated macrophages and survival in classic Hodgkin's lymphoma. N Engl J Med 2010; 362: 875–85.
    • (2010) N Engl J Med , vol.362 , pp. 875-885
    • Steidl, C.1    Lee, T.2    Shah, S.P.3
  • 120
    • 80855130756 scopus 로고    scopus 로고
    • Prognostic implication of types of tumor-associated macrophages in Hodgkin lymphoma
    • Zaki MA, Wada N, Ikeda J et al. Prognostic implication of types of tumor-associated macrophages in Hodgkin lymphoma. Virchows Arch 2011; 459: 361–6.
    • (2011) Virchows Arch , vol.459 , pp. 361-366
    • Zaki, M.A.1    Wada, N.2    Ikeda, J.3
  • 121
    • 84868116570 scopus 로고    scopus 로고
    • Tumor-associated macrophages predict inferior outcomes in classic Hodgkin lymphoma: A correlative study from the E2496 Intergroup trial
    • Tan KL, Scott DW, Hong F et al. Tumor-associated macrophages predict inferior outcomes in classic Hodgkin lymphoma: A correlative study from the E2496 Intergroup trial. Blood 2012; 120: 3280–7.
    • (2012) Blood , vol.120 , pp. 3280-3287
    • Tan, K.L.1    Scott, D.W.2    Hong, F.3
  • 122
    • 84897935943 scopus 로고    scopus 로고
    • CD163 immunohistochemistry is superior to CD68 in predicting outcome in classical Hodgkin lymphoma
    • Klein JL, Nguyen TT, Bien-Willner GA et al. CD163 immunohistochemistry is superior to CD68 in predicting outcome in classical Hodgkin lymphoma. Am J Clin Pathol 2014; 141: 381–7.
    • (2014) Am J Clin Pathol , vol.141 , pp. 381-387
    • Klein, J.L.1    Nguyen, T.T.2    Bien-Willner, G.A.3
  • 123
    • 84900415102 scopus 로고    scopus 로고
    • CD163 expression was associated with angiogenesis and shortened survival in patients with uniformly treated classical Hodgkin lymphoma
    • Koh YW, Park CS, Yoon DH, Suh C, Huh J. CD163 expression was associated with angiogenesis and shortened survival in patients with uniformly treated classical Hodgkin lymphoma. PLoS One 2014; 9 :e87066
    • (2014) PLoS One , vol.9 , pp. e87066
    • Koh, Y.W.1    Park, C.S.2    Yoon, D.H.3    Suh, C.4    Huh, J.5
  • 124
    • 84857534118 scopus 로고    scopus 로고
    • Lack of association of tumor-associated macrophages with clinical outcome in patients with classical Hodgkin's lymphoma
    • Azambuja D, Natkunam Y, Biasoli I et al. Lack of association of tumor-associated macrophages with clinical outcome in patients with classical Hodgkin's lymphoma. Ann Oncol 2012; 23: 736–42.
    • (2012) Ann Oncol , vol.23 , pp. 736-742
    • Azambuja, D.1    Natkunam, Y.2    Biasoli, I.3
  • 125
    • 84929352980 scopus 로고    scopus 로고
    • Macrophage polarization reflects T cell composition of tumor microenvironment in pediatric classical Hodgkin lymphoma and has impact on survival
    • Barros MH, Segges P, Vera-Lozada G, Hassan R, Niedobitek G. Macrophage polarization reflects T cell composition of tumor microenvironment in pediatric classical Hodgkin lymphoma and has impact on survival. PLoS One 2015; 10 :e0124531
    • (2015) PLoS One , vol.10 , pp. e0124531
    • Barros, M.H.1    Segges, P.2    Vera-Lozada, G.3    Hassan, R.4    Niedobitek, G.5
  • 126
    • 8644252736 scopus 로고    scopus 로고
    • Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells
    • Dave SS, Wright G, Tan B et al. Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells. N Engl J Med 2004; 351: 2159–69.
    • (2004) N Engl J Med , vol.351 , pp. 2159-2169
    • Dave, S.S.1    Wright, G.2    Tan, B.3
  • 127
    • 24744438473 scopus 로고    scopus 로고
    • Analysis of multiple biomarkers shows that lymphoma-associated macrophage (LAM) content is an independent predictor of survival in follicular lymphoma (FL)
    • Farinha P, Masoudi H, Skinnider BF et al. Analysis of multiple biomarkers shows that lymphoma-associated macrophage (LAM) content is an independent predictor of survival in follicular lymphoma (FL). Blood 2005; 106: 2169–74.
    • (2005) Blood , vol.106 , pp. 2169-2174
    • Farinha, P.1    Masoudi, H.2    Skinnider, B.F.3
  • 128
    • 38649108461 scopus 로고    scopus 로고
    • High numbers of tumor-associated macrophages have an adverse prognostic value that can be circumvented by rituximab in patients with follicular lymphoma enrolled onto the GELA-GOELAMS FL-2000 trial
    • Canioni D, Salles G, Mounier N et al. High numbers of tumor-associated macrophages have an adverse prognostic value that can be circumvented by rituximab in patients with follicular lymphoma enrolled onto the GELA-GOELAMS FL-2000 trial. J Clin Oncol 2008; 26: 440–6.
    • (2008) J Clin Oncol , vol.26 , pp. 440-446
    • Canioni, D.1    Salles, G.2    Mounier, N.3
  • 129
    • 35348843627 scopus 로고    scopus 로고
    • A high tumor-associated macrophage content predicts favorable outcome in follicular lymphoma patients treated with rituximab and cyclophosphamide-doxorubicin-vincristine-prednisone
    • Taskinen M, Karjalainen-Lindsberg ML, Nyman H, Eerola LM, Leppä S. A high tumor-associated macrophage content predicts favorable outcome in follicular lymphoma patients treated with rituximab and cyclophosphamide-doxorubicin-vincristine-prednisone. Clin Cancer Res 2007; 13: 5784–9.
    • (2007) Clin Cancer Res , vol.13 , pp. 5784-5789
    • Taskinen, M.1    Karjalainen-Lindsberg, M.L.2    Nyman, H.3    Eerola, L.M.4    Leppä, S.5
  • 130
    • 37149013899 scopus 로고    scopus 로고
    • Biologic predictors in follicular lymphoma: Importance of markers of immune response
    • Kelley T, Beck R, Absi A, Jin T, Pohlman B, Hsi E. Biologic predictors in follicular lymphoma: Importance of markers of immune response. Leuk Lymphoma 2007; 48: 2403–11.
    • (2007) Leuk Lymphoma , vol.48 , pp. 2403-2411
    • Kelley, T.1    Beck, R.2    Absi, A.3    Jin, T.4    Pohlman, B.5    Hsi, E.6
  • 131
    • 84868003454 scopus 로고    scopus 로고
    • High expression of tumor-infiltrating macrophages correlates with poor prognosis in patients with diffuse large B-cell lymphoma
    • Cai QC, Liao H, Lin SX et al. High expression of tumor-infiltrating macrophages correlates with poor prognosis in patients with diffuse large B-cell lymphoma. Med Oncol 2012; 29: 2317–22.
    • (2012) Med Oncol , vol.29 , pp. 2317-2322
    • Cai, Q.C.1    Liao, H.2    Lin, S.X.3
  • 132
    • 84255178280 scopus 로고    scopus 로고
    • Tumour-associated macrophages in diffuse large B-cell lymphoma: A study of the Osaka Lymphoma Study Group
    • Wada N, Zaki MA, Hori Y et al. Tumour-associated macrophages in diffuse large B-cell lymphoma: A study of the Osaka Lymphoma Study Group. Histopathology 2012; 60: 313–9.
    • (2012) Histopathology , vol.60 , pp. 313-319
    • Wada, N.1    Zaki, M.A.2    Hori, Y.3
  • 133
    • 46749133932 scopus 로고    scopus 로고
    • Expression of CD68+ tumor-associated macrophages in patients with diffuse large B-cell lymphoma and its relation to prognosis
    • Hasselblom S, Hansson U, Sigurdardottir M, Nilsson-Ehle H, Ridell B, Andersson PO. Expression of CD68+ tumor-associated macrophages in patients with diffuse large B-cell lymphoma and its relation to prognosis. Pathol Int 2008; 58: 529–32.
    • (2008) Pathol Int , vol.58 , pp. 529-532
    • Hasselblom, S.1    Hansson, U.2    Sigurdardottir, M.3    Nilsson-Ehle, H.4    Ridell, B.5    Andersson, P.O.6
  • 134
    • 84930923761 scopus 로고    scopus 로고
    • High density of CD68+/CD163+ tumour-associated macrophages (M2-TAM) at diagnosis is significantly correlated to unfavorable prognostic factors and to poor clinical outcomes in patients with diffuse large B-cell lymphoma
    • Marchesi F, Cirillo M, Bianchi A et al. High density of CD68+/CD163+ tumour-associated macrophages (M2-TAM) at diagnosis is significantly correlated to unfavorable prognostic factors and to poor clinical outcomes in patients with diffuse large B-cell lymphoma. Hematol Oncol 2015; 33: 110–2.
    • (2015) Hematol Oncol , vol.33 , pp. 110-112
    • Marchesi, F.1    Cirillo, M.2    Bianchi, A.3
  • 135
    • 84912123889 scopus 로고    scopus 로고
    • An increase of M2 macrophages predicts poor prognosis in patients with diffuse large B-cell lymphoma treated with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone
    • Nam SJ, Go H, Paik JH et al. An increase of M2 macrophages predicts poor prognosis in patients with diffuse large B-cell lymphoma treated with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone. Leuk Lymphoma 2014; 55: 2466–76.
    • (2014) Leuk Lymphoma , vol.55 , pp. 2466-2476
    • Nam, S.J.1    Go, H.2    Paik, J.H.3
  • 136
    • 64249111614 scopus 로고    scopus 로고
    • M2 macrophages phagocytose rituximab-opsonized leukemic targets more efficiently than m1 cells in vitro
    • Leidi M, Gotti E, Bologna L et al. M2 macrophages phagocytose rituximab-opsonized leukemic targets more efficiently than m1 cells in vitro. J Immunol 2009; 182: 4415–22.
    • (2009) J Immunol , vol.182 , pp. 4415-4422
    • Leidi, M.1    Gotti, E.2    Bologna, L.3
  • 137
    • 84939831345 scopus 로고    scopus 로고
    • The prognostic impact of CD163-positive macrophages in follicular lymphoma: A study from the BC Cancer Agency and the Lymphoma Study Association
    • Kridel R, Xerri L, Gelas-Dore B et al. The prognostic impact of CD163-positive macrophages in follicular lymphoma: A study from the BC Cancer Agency and the Lymphoma Study Association. Clin Cancer Res 2015; 21: 3428–35.
    • (2015) Clin Cancer Res , vol.21 , pp. 3428-3435
    • Kridel, R.1    Xerri, L.2    Gelas-Dore, B.3
  • 138
    • 84880740892 scopus 로고    scopus 로고
    • + tumor-associated macrophages in patients with adult T-cell leukemia/lymphoma
    • + tumor-associated macrophages in patients with adult T-cell leukemia/lymphoma. Cancer Sci 2013; 104: 945–51.
    • (2013) Cancer Sci , vol.104 , pp. 945-951
    • Komohara, Y.1    Niino, D.2    Saito, Y.3
  • 139
    • 84922575453 scopus 로고    scopus 로고
    • Role of CD204-positive tumor-associated macrophages in adult T-cell leukemia/lymphoma
    • Saito Y, Komohara Y, Niino D et al. Role of CD204-positive tumor-associated macrophages in adult T-cell leukemia/lymphoma. J Clin Exp Hematop 2014; 54: 59–65.
    • (2014) J Clin Exp Hematop , vol.54 , pp. 59-65
    • Saito, Y.1    Komohara, Y.2    Niino, D.3
  • 140
    • 77949695294 scopus 로고    scopus 로고
    • Ratio of M2 macrophage expression is closely associated with poor prognosis for angioimmunoblastic T-cell lymphoma (AITL)
    • Niino D, Komohara Y, Murayama T et al. Ratio of M2 macrophage expression is closely associated with poor prognosis for angioimmunoblastic T-cell lymphoma (AITL). Pathol Int 2010; 60: 278–83.
    • (2010) Pathol Int , vol.60 , pp. 278-283
    • Niino, D.1    Komohara, Y.2    Murayama, T.3
  • 141
    • 84865746838 scopus 로고    scopus 로고
    • + cells in lesional skin and serum levels of soluble CD163 with disease progression of cutaneous T cell lymphoma
    • + cells in lesional skin and serum levels of soluble CD163 with disease progression of cutaneous T cell lymphoma. J Dermatol Sci 2012; 68: 45–51.
    • (2012) J Dermatol Sci , vol.68 , pp. 45-51
    • Sugaya, M.1    Miyagaki, T.2    Ohmatsu, H.3
  • 142
    • 84880285285 scopus 로고    scopus 로고
    • High numbers of tumor-associated macrophages correlate with poor prognosis in patients with mature T- and natural killer cell lymphomas
    • Lin ZX, Bai B, Cai QC et al. High numbers of tumor-associated macrophages correlate with poor prognosis in patients with mature T- and natural killer cell lymphomas. Med Oncol 2012; 29: 3522–8.
    • (2012) Med Oncol , vol.29 , pp. 3522-3528
    • Lin, Z.X.1    Bai, B.2    Cai, Q.C.3
  • 143
    • 84938742710 scopus 로고    scopus 로고
    • High numbers of CD68+ tumor-associated macrophages correlate with poor prognosis in extranodal NK/T-cell lymphoma, nasal type
    • Wang H, Li P, Wang L et al. High numbers of CD68+ tumor-associated macrophages correlate with poor prognosis in extranodal NK/T-cell lymphoma, nasal type. Ann Hematol 2015; 94: 1535–44.
    • (2015) Ann Hematol , vol.94 , pp. 1535-1544
    • Wang, H.1    Li, P.2    Wang, L.3
  • 144
    • 84979853631 scopus 로고    scopus 로고
    • Cyr61 promotes CD204 expression and the migration of macrophages via MEK/ERK pathway in esophageal squamous cell carcinoma
    • Shigeoka M, Urakawa N, Nishio M et al. Cyr61 promotes CD204 expression and the migration of macrophages via MEK/ERK pathway in esophageal squamous cell carcinoma. Cancer Med 2014; 4: 437–46.
    • (2014) Cancer Med , vol.4 , pp. 437-446
    • Shigeoka, M.1    Urakawa, N.2    Nishio, M.3
  • 145
    • 0347951196 scopus 로고    scopus 로고
    • Hemoglobin scavenger receptor CD163 mediates interleukin-10 release and heme oxygenase-1 synthesis: antiinflammatory monocyte–macrophage responses in vitro, in resolving skin blisters in vivo, and after cardiopulmonary bypass surgery
    • Philippidis P, Mason JC, Evans BJ et al. Hemoglobin scavenger receptor CD163 mediates interleukin-10 release and heme oxygenase-1 synthesis: antiinflammatory monocyte–macrophage responses in vitro, in resolving skin blisters in vivo, and after cardiopulmonary bypass surgery. Circ Res 2004; 94: 119–26.
    • (2004) Circ Res , vol.94 , pp. 119-126
    • Philippidis, P.1    Mason, J.C.2    Evans, B.J.3
  • 146
    • 79961128535 scopus 로고    scopus 로고
    • Suppression of TLR4-mediated inflammatory response by macrophage class A scavenger receptor (CD204)
    • Ohnishi K, Komohara Y, Fujiwara Y et al. Suppression of TLR4-mediated inflammatory response by macrophage class A scavenger receptor (CD204). Biochem Biophys Res Commun 2011; 411: 516–22.
    • (2011) Biochem Biophys Res Commun , vol.411 , pp. 516-522
    • Ohnishi, K.1    Komohara, Y.2    Fujiwara, Y.3
  • 147
    • 84957824859 scopus 로고    scopus 로고
    • Tumor-associated macrophages: Potential therapeutic targets for anti-cancer therapy
    • Komohara Y, Fujiwara Y, Ohnishi K, Takeya M. Tumor-associated macrophages: Potential therapeutic targets for anti-cancer therapy. Adv Drug Deliv Rev 2016; 99: 180–5.
    • (2016) Adv Drug Deliv Rev , vol.99 , pp. 180-185
    • Komohara, Y.1    Fujiwara, Y.2    Ohnishi, K.3    Takeya, M.4
  • 148
    • 84928226005 scopus 로고    scopus 로고
    • The interaction of anticancer therapies with tumor-associated macrophages
    • Mantovani A, Allevena P. The interaction of anticancer therapies with tumor-associated macrophages. J Exp Med 2015; 212: 435–55.
    • (2015) J Exp Med , vol.212 , pp. 435-455
    • Mantovani, A.1    Allevena, P.2
  • 149
    • 80355146399 scopus 로고    scopus 로고
    • Transcriptional regulation of macrophage polarization: Enabling diversity with identity
    • Lawrence T, Natoli G. Transcriptional regulation of macrophage polarization: Enabling diversity with identity. Nat Rev Immunol 2011; 11: 750–61.
    • (2011) Nat Rev Immunol , vol.11 , pp. 750-761
    • Lawrence, T.1    Natoli, G.2
  • 150
    • 78650218768 scopus 로고    scopus 로고
    • Corosolic acid inhibits glioblastoma cell proliferation by suppressing the activation of signal transducer and activator of transcription-3 and nuclear factor-kappa B in tumor cells and tumor-associated macrophages
    • Fujiwara Y, Komohara Y, Ikeda T, Takeya M. Corosolic acid inhibits glioblastoma cell proliferation by suppressing the activation of signal transducer and activator of transcription-3 and nuclear factor-kappa B in tumor cells and tumor-associated macrophages. Cancer Sci 2011; 102: 206–11.
    • (2011) Cancer Sci , vol.102 , pp. 206-211
    • Fujiwara, Y.1    Komohara, Y.2    Ikeda, T.3    Takeya, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.