Vitamin E forms inhibit IL-13/STAT6-induced eotaxin-3 secretion by up-regulation of PAR4, an endogenous inhibitor of atypical PKC in human lung epithelial cells

Journal of Nutritional Biochemistry

Volumn 23, Issue 6, 2012, Pages 602-608

  Wang, Yun ^a   Moreland, Michelle ^a   Wagner, James G ^b   Ames, Bruce N ^c   Illek, Beate ^c   Peden, David B ^d   Jiang, Qing ^a  

^a PURDUE UNIVERSITY   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c CHILDREN S HOSPITAL OAKLAND   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Asthma; Inflammation; Tocopherol; Tocotrienol

Indexed keywords

ALPHA TOCOPHEROL; ALPHA TOCOPHEROL DERIVATIVE; ANTIASTHMATIC AGENT; DELTA TOCOPHEROL; EOTAXIN 3; GAMMA TOCOPHEROL; GAMMA TOCOTRIENOL; INTERLEUKIN 13; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE C; PROTEINASE ACTIVATED RECEPTOR 4; SMALL INTERFERING RNA; STAT6 PROTEIN; STRESS ACTIVATED PROTEIN KINASE;

ARTICLE; CONTROLLED STUDY; DNA BINDING; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; UPREGULATION;

ALPHA-TOCOPHEROL; ANTI-ASTHMATIC AGENTS; APOPTOSIS REGULATORY PROTEINS; CHEMOKINES, CC; CHROMANS; EPITHELIAL CELLS; GAMMA-TOCOPHEROL; HUMANS; INTERLEUKIN-13; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN KINASE C; SIGNAL TRANSDUCTION; STAT6 TRANSCRIPTION FACTOR; TOCOPHEROLS; TRANSCRIPTION FACTORS; UP-REGULATION; VITAMIN E;

EID: 84860883332     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2011.03.003     Document Type: Article

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