Single-cell sequencing maps gene expression to mutational phylogenies in PDGF- and EGF-driven gliomas

Molecular Systems Biology

Volumn 12, Issue 11, 2016, Pages

  Müller, Sören ^a,b   Liu, Siyuan John ^a,b   Di Lullo, Elizabeth ^b   Malatesta, Martina ^a,b   Pollen, Alex A ^b   Nowakowski, Tomasz J ^b   Kohanbash, Gary ^a   Aghi, Manish ^a   Kriegstein, Arnold R ^b   Lim, Daniel A ^a,b,c   Diaz, Aaron ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

copy number variation; glioblastoma; PDGFRA; single cell RNA sequencing; tumor phylogeny

Indexed keywords

AURORA B KINASE; EPIDERMAL GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; EGFR PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR RECEPTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; COPY NUMBER VARIATION; DIMERIZATION; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; GENETIC TRANSCRIPTION; GLIOMA; HUMAN; HUMAN TISSUE; PHYLOGENETIC TREE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN DOMAIN; UPREGULATION; WHOLE EXOME SEQUENCING; BRAIN TUMOR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETIC HETEROGENEITY; GENETICS; GLIOBLASTOMA; MUTATION; PROCEDURES; SEQUENCE ANALYSIS; SINGLE CELL ANALYSIS;

BRAIN NEOPLASMS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; GENETIC HETEROGENEITY; GLIOBLASTOMA; HUMANS; MUTATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; SEQUENCE ANALYSIS, RNA; SINGLE-CELL ANALYSIS;

EID: 84997605143     PISSN: None     EISSN: 17444292     Source Type: Journal    
DOI: 10.15252/msb.20166969     Document Type: Article

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