Disassembly of amphiphilic small molecular prodrug with fluorescence switch induced by pH and folic acid receptors for targeted delivery and controlled release

Colloids and Surfaces B: Biointerfaces

Volumn 150, Issue , 2017, Pages 50-58

  Xu, Zhigang ^a   Shi, Xiaoxiao ^a   Hou, Meili ^a   Xue, Peng ^a   Gao, Yong E ^a   Liu, Shiying ^b   Kang, Yuejun ^a  

^a SOUTHWEST UNIVERSITY   (China)

^b Nanyang Technological University   (Singapore)

Author keywords

Cancer therapy; Controlled release; Diagnosis; Drug delivery; Small molecular prodrug

Indexed keywords

CELLS; CYTOLOGY; CYTOTOXICITY; DIAGNOSIS; DRUG DELIVERY; FLUORESCENCE; NANOPARTICLES; ORGANIC ACIDS; TUMORS;

CANCER THERAPY; CONTROLLED RELEASE; DRUG DELIVERY SYSTEM; FLUORESCENCE SWITCH; MICELLAR NANOPARTICLES; NEUTRAL ENVIRONMENT; PRODRUGS; TRIGGERED DRUG RELEASE;

CONTROLLED DRUG DELIVERY;

AMPHIPHILIC SMALL MOLECULAR PRODRUG; DOXORUBICIN; FOLIC ACID; NANOPARTICLE; PRODRUG; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DELAYED RELEASE FORMULATION; FOLATE RECEPTOR; HYDRAZONE DERIVATIVE; MICELLE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; FLUORESCENCE; HUMAN; HUMAN CELL; IN VITRO STUDY; PH; PRIORITY JOURNAL; TUMOR CELL; TUMOR MICROENVIRONMENT; CHEMISTRY; DELAYED RELEASE FORMULATION; ENDOSOME; HELA CELL LINE; MCF-7 CELL LINE; METABOLISM; MICELLE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SPECTROFLUOROMETRY;

ANTINEOPLASTIC AGENTS; DELAYED-ACTION PREPARATIONS; DOXORUBICIN; DRUG DELIVERY SYSTEMS; ENDOSOMES; FLUORESCENCE; FOLATE RECEPTORS, GPI-ANCHORED; FOLIC ACID; HELA CELLS; HUMANS; HYDRAZONES; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; MCF-7 CELLS; MICELLES; NANOPARTICLES; PRODRUGS; SPECTROMETRY, FLUORESCENCE;

EID: 84997482178     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2016.11.021     Document Type: Article

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