ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins

Nature Communications

Volumn 7, Issue , 2016, Pages

  Villarroya Beltri, Carolina ^a,b   Baixauli, Francesc ^a,b   Mittelbrunn, Mariá ^a   Fernández Delgado, Irene ^a,b   Torralba, Daniel ^a,b   Moreno Gonzalo, Olga ^a,b   Baldanta, Sara ^b   Enrich, Carlos ^c   Guerra, Susana ^b   Sánchez Madrid, Francisco ^a,b  

^a CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c Centre de Recerca Biomèdica CELLEX   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR SUSCEPTIBILITY GENE 101 PROTEIN; UBIQUITIN; CYTOKINE; DNA BINDING PROTEIN; ESCRT PROTEIN; G1P2 PROTEIN, MOUSE; ISG15 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; UBIQUITIN THIOLESTERASE; USP18 PROTEIN, MOUSE;

CELLS AND CELL COMPONENTS; CHEMICAL ALTERATION; DEGRADATION; ENZYME ACTIVITY; MEMBRANE; PLASMA; PROTEIN; RODENT; SECRETION;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CELL COMMUNICATION; CONJUGATION; CONTROLLED STUDY; EXOSOME; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; ISGYLATION; LYSOSOME; MOUSE; MULTIVESICULAR BODY; NONHUMAN; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN TARGETING; REGULATORY MECHANISM; ANIMAL; GENETICS; HEK293 CELL LINE; JURKAT CELL LINE; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; SECRETION (PROCESS); T LYMPHOCYTE;

MUS;

ANIMALS; AUTOPHAGY; CYTOKINES; DNA-BINDING PROTEINS; ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT; EXOSOMES; HEK293 CELLS; HUMANS; JURKAT CELLS; LYSOSOMES; MACROPHAGES; MICE; MICE, KNOCKOUT; MULTIVESICULAR BODIES; T-LYMPHOCYTES; TRANSCRIPTION FACTORS; UBIQUITIN THIOLESTERASE; UBIQUITINS;

EID: 84997335299     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms13588     Document Type: Article

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