Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire

Nature Communications

Volumn 7, Issue , 2016, Pages

  Yeung, Yik Andy ^a   Foletti, Davide ^a,d   Deng, Xiaodi ^a,b   Abdiche, Yasmina ^a   Strop, Pavel ^a,b,d   Glanville, Jacob ^a,c   Pitts, Steven ^a   Lindquist, Kevin ^a   Sundar, Purnima D ^a   Sirota, Marina ^a,e   Hasa Moreno, Adela ^a   Pham, Amber ^a   Melton Witt, Jody ^a   Ni, Irene ^a   Pons, Jaume ^a,f   Shelton, David ^a   Rajpal, Arvind ^a,b   Chaparro Riggers, Javier ^a  

^a R and D Monogram Biosciences   (United States)

^b Bristol Myers Squibb   (United States)

^c Distributed Bio   (United States)

^d University of California San Francisco ^*  (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f Alexo Therapeutics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN KAPPA CHAIN; NEUTRALIZING ANTIBODY; VIRULENCE FACTOR; BACTERIAL PROTEIN; BACTERIUM ANTIBODY; LONG UNTRANSLATED RNA; MALAT1 LONG NON-CODING RNA, HUMAN; NEAT1 LONG NON-CODING RNA, HUMAN;

ANTIBODY; BACTERIUM; CELLS AND CELL COMPONENTS; HOST-PATHOGEN INTERACTION; IMMUNE RESPONSE; IMMUNE SYSTEM; NEUTRALIZATION; PATHOGEN; PROTEIN; VIRULENCE;

ADAPTIVE IMMUNITY; ANTIBODY TITER; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ARTICLE; COMMENSALISM; CONTROLLED STUDY; EPITOPE MAPPING; HEAVY CHAIN; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; HYDROPHOBICITY; IMMUNOGLOBULIN GENE; MEMORY CELL; NONHUMAN; NORMAL HUMAN; PHAGE DISPLAY; PROTEIN CONFORMATION; PROTEIN DOMAIN; STAPHYLOCOCCUS AUREUS; STEREOSPECIFICITY; STRUCTURE ANALYSIS; SURFACE AREA; B LYMPHOCYTE; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; MICROBIOLOGY; MOLECULAR MODEL; STAPHYLOCOCCUS INFECTION;

STAPHYLOCOCCUS AUREUS;

ANTIBODIES, BACTERIAL; ANTIBODIES, NEUTRALIZING; B-LYMPHOCYTES; BACTERIAL PROTEINS; HUMANS; IMMUNOLOGIC MEMORY; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN DOMAINS; RNA, LONG NONCODING; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; VIRULENCE FACTORS;

EID: 84996484130     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms13376     Document Type: Article

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