메뉴 건너뛰기




Volumn 23, Issue 9, 2015, Pages 529-536

Complex host genetic susceptibility to Staphylococcus aureus infections

Author keywords

Bacteremia; Genome wide association study; Host genetic susceptibility; Immune response; Polymorphisms; Staphylococcus aureus

Indexed keywords

BETA DEFENSIN 1; C REACTIVE PROTEIN; INTERLEUKIN 4; VITAMIN D RECEPTOR;

EID: 84940461787     PISSN: 0966842X     EISSN: 18784380     Source Type: Journal    
DOI: 10.1016/j.tim.2015.05.008     Document Type: Review
Times cited : (30)

References (61)
  • 1
    • 84887177178 scopus 로고    scopus 로고
    • Role of protein A in the evasion of host adaptive immune responses by Staphylococcus aureus
    • Falugi F., et al. Role of protein A in the evasion of host adaptive immune responses by Staphylococcus aureus. MBio 2013, 4:e00575-e613.
    • (2013) MBio , vol.4 , pp. e00575-e613
    • Falugi, F.1
  • 2
    • 67650508387 scopus 로고    scopus 로고
    • Reclassification of Staphylococcus aureus nasal carriage types
    • van Belkum A., et al. Reclassification of Staphylococcus aureus nasal carriage types. J. Infect. Dis. 2009, 199:1820-1826.
    • (2009) J. Infect. Dis. , vol.199 , pp. 1820-1826
    • van Belkum, A.1
  • 3
    • 0032551901 scopus 로고    scopus 로고
    • Staphylococcus aureus infections
    • Lowy F.D. Staphylococcus aureus infections. N. Engl. J. Med. 1998, 339:520-532.
    • (1998) N. Engl. J. Med. , vol.339 , pp. 520-532
    • Lowy, F.D.1
  • 4
    • 33244473794 scopus 로고    scopus 로고
    • Community-associated methicillin-resistant Staphylococcus aureus and its emerging virulence
    • Shukla S.K. Community-associated methicillin-resistant Staphylococcus aureus and its emerging virulence. Clin. Med. Res. 2005, 3:57-60.
    • (2005) Clin. Med. Res. , vol.3 , pp. 57-60
    • Shukla, S.K.1
  • 5
    • 28044446133 scopus 로고    scopus 로고
    • The role of nasal carriage in Staphylococcus aureus infections
    • Wertheim H.F., et al. The role of nasal carriage in Staphylococcus aureus infections. Lancet Infect. Dis. 2005, 5:751-762.
    • (2005) Lancet Infect. Dis. , vol.5 , pp. 751-762
    • Wertheim, H.F.1
  • 6
    • 0029842548 scopus 로고    scopus 로고
    • Genetic localization of a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31-q33
    • Marquet S., et al. Genetic localization of a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31-q33. Nat. Genet. 1996, 14:181-184.
    • (1996) Nat. Genet. , vol.14 , pp. 181-184
    • Marquet, S.1
  • 7
    • 27944453150 scopus 로고    scopus 로고
    • Schistosoma mansoni secretes a chemokine binding protein with anti-inflammatory activity
    • Smith P., et al. Schistosoma mansoni secretes a chemokine binding protein with anti-inflammatory activity. J. Exp. Med. 2005, 202:1319-1325.
    • (2005) J. Exp. Med. , vol.202 , pp. 1319-1325
    • Smith, P.1
  • 8
    • 78649489009 scopus 로고    scopus 로고
    • Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
    • Franke A., et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat. Genet. 2010, 42:1118-1125.
    • (2010) Nat. Genet. , vol.42 , pp. 1118-1125
    • Franke, A.1
  • 9
    • 79952195585 scopus 로고    scopus 로고
    • Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
    • Anderson C.A., et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat. Genet. 2011, 43:246-252.
    • (2011) Nat. Genet. , vol.43 , pp. 246-252
    • Anderson, C.A.1
  • 10
    • 84866924593 scopus 로고    scopus 로고
    • UK Primary Biliary Cirrhosis (PBC) Consortium; Wellcome Trust Case Control Consortium 3. 2012. Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis
    • Liu J.Z., et al. UK Primary Biliary Cirrhosis (PBC) Consortium; Wellcome Trust Case Control Consortium 3. 2012. Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis. Nat. Genet. 2012, 44:1137-1141.
    • (2012) Nat. Genet. , vol.44 , pp. 1137-1141
    • Liu, J.Z.1
  • 11
    • 77956643281 scopus 로고    scopus 로고
    • Infectious diseases not immune to genome-wide association
    • de Bakker P.I., Telenti A. Infectious diseases not immune to genome-wide association. Nat. Genet. 2010, 42:731-732.
    • (2010) Nat. Genet. , vol.42 , pp. 731-732
    • de Bakker, P.I.1    Telenti, A.2
  • 12
    • 34848918479 scopus 로고    scopus 로고
    • The constitutive capacity of human keratinocytes to kill Staphylococcus aureus is dependent on beta-defensin 3
    • Kisich K.O., et al. The constitutive capacity of human keratinocytes to kill Staphylococcus aureus is dependent on beta-defensin 3. J. Invest. Dermatol. 2007, 127:2368-2380.
    • (2007) J. Invest. Dermatol. , vol.127 , pp. 2368-2380
    • Kisich, K.O.1
  • 13
    • 79956300649 scopus 로고    scopus 로고
    • Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
    • Kawai T., Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 2011, 34:637-650.
    • (2011) Immunity , vol.34 , pp. 637-650
    • Kawai, T.1    Akira, S.2
  • 14
    • 22244439504 scopus 로고    scopus 로고
    • Recognition of Staphylococcus aureus by the innate immune system
    • Fournier B., Philpott D.J. Recognition of Staphylococcus aureus by the innate immune system. Clin. Microbiol. Rev. 2005, 18:521-540.
    • (2005) Clin. Microbiol. Rev. , vol.18 , pp. 521-540
    • Fournier, B.1    Philpott, D.J.2
  • 15
    • 57149109128 scopus 로고    scopus 로고
    • Immunological mechanisms underlying the genetic predisposition to severe Staphylococcus aureus infection in the mouse model
    • von Köckritz-Blickwede M., et al. Immunological mechanisms underlying the genetic predisposition to severe Staphylococcus aureus infection in the mouse model. Am. J. Pathol. 2008, 173:1657-1668.
    • (2008) Am. J. Pathol. , vol.173 , pp. 1657-1668
    • von Köckritz-Blickwede, M.1
  • 16
    • 85017747080 scopus 로고    scopus 로고
    • Subcutaneous infection with S. aureus in mice reveals association of resistance with influx of neutrophils and Th2 response
    • Nippe N., et al. Subcutaneous infection with S. aureus in mice reveals association of resistance with influx of neutrophils and Th2 response. J. Immunol. 2011, 193:1090-1099.
    • (2011) J. Immunol. , vol.193 , pp. 1090-1099
    • Nippe, N.1
  • 17
    • 84880821538 scopus 로고    scopus 로고
    • Signaling via the IL-20 receptor inhibits cutaneous production of IL-1β and IL-17A to promote infection with methicillin-resistant Staphylococcus aureus
    • Myles I.A., et al. Signaling via the IL-20 receptor inhibits cutaneous production of IL-1β and IL-17A to promote infection with methicillin-resistant Staphylococcus aureus. Nat. Immunol. 2013, 14:804-811.
    • (2013) Nat. Immunol. , vol.14 , pp. 804-811
    • Myles, I.A.1
  • 18
    • 84856088598 scopus 로고    scopus 로고
    • Host-pathogen interactions between the skin and Staphylococcus aureus
    • Krishna S., Miller L.S. Host-pathogen interactions between the skin and Staphylococcus aureus. Curr. Opin. Microbiol. 2012, 15:28-35.
    • (2012) Curr. Opin. Microbiol. , vol.15 , pp. 28-35
    • Krishna, S.1    Miller, L.S.2
  • 19
    • 0034669910 scopus 로고    scopus 로고
    • Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection
    • Takeuchi O., et al. Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection. J. Immunol. 2000, 165:5392-5396.
    • (2000) J. Immunol. , vol.165 , pp. 5392-5396
    • Takeuchi, O.1
  • 20
    • 79251578315 scopus 로고    scopus 로고
    • T and B cells are not required for clearing Staphylococcus aureus in systemic infection despite a strong TLR2-MyD88-dependent T cell activation
    • Schmaler M., et al. T and B cells are not required for clearing Staphylococcus aureus in systemic infection despite a strong TLR2-MyD88-dependent T cell activation. J. Immunol. 2011, 186:443-452.
    • (2011) J. Immunol. , vol.186 , pp. 443-452
    • Schmaler, M.1
  • 21
    • 63149091710 scopus 로고    scopus 로고
    • Critical role of NOD2 in regulating the immune response to Staphylococcus aureus
    • Deshmukh H.S., et al. Critical role of NOD2 in regulating the immune response to Staphylococcus aureus. Infect. Immun. 2009, 77:1376-1382.
    • (2009) Infect. Immun. , vol.77 , pp. 1376-1382
    • Deshmukh, H.S.1
  • 22
    • 32644479365 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't know
    • Shi Y., et al. Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't know. Cell Res. 2006, 16:126-133.
    • (2006) Cell Res. , vol.16 , pp. 126-133
    • Shi, Y.1
  • 23
    • 78149328425 scopus 로고    scopus 로고
    • Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses
    • Ahn S.H., et al. Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses. PLoS Pathog. 2010, 6:e1001088.
    • (2010) PLoS Pathog. , vol.6 , pp. e1001088
    • Ahn, S.H.1
  • 24
    • 84903464217 scopus 로고    scopus 로고
    • Dusp3 and Psme3 are associated with murine susceptibility to Staphylococcus aureus infection and human sepsis
    • Yan Q., et al. Dusp3 and Psme3 are associated with murine susceptibility to Staphylococcus aureus infection and human sepsis. PLoS Pathog. 2014, 10:e1004149.
    • (2014) PLoS Pathog. , vol.10 , pp. e1004149
    • Yan, Q.1
  • 25
    • 84879131303 scopus 로고    scopus 로고
    • Staphylococcus aureus α11-toxin: nearly a century of intrigue
    • Berube B.J., Bubeck-Wardenburg J. Staphylococcus aureus α11-toxin: nearly a century of intrigue. Toxins (Basel) 2013, 5:1140-1166.
    • (2013) Toxins (Basel) , vol.5 , pp. 1140-1166
    • Berube, B.J.1    Bubeck-Wardenburg, J.2
  • 26
    • 84862804469 scopus 로고    scopus 로고
    • Genetic requirement for ADAM10 in severe Staphylococcus aureus skin infection
    • Inoshima N., et al. Genetic requirement for ADAM10 in severe Staphylococcus aureus skin infection. J. Invest. Dermatol. 2012, 132:1513-1516.
    • (2012) J. Invest. Dermatol. , vol.132 , pp. 1513-1516
    • Inoshima, N.1
  • 27
    • 84866932832 scopus 로고    scopus 로고
    • Influence of host genetics and environment on nasal carriage of Staphylococcus aureus in Danish middle-aged and elderly twins
    • Andersen P.S., et al. Influence of host genetics and environment on nasal carriage of Staphylococcus aureus in Danish middle-aged and elderly twins. J. Infect. Dis. 2012, 206:1178-1184.
    • (2012) J. Infect. Dis. , vol.206 , pp. 1178-1184
    • Andersen, P.S.1
  • 28
    • 77955950311 scopus 로고    scopus 로고
    • Are host genetics the predominant determinant of persistent nasal Staphylococcus aureus carriage in humans?
    • Ruimy R., et al. Are host genetics the predominant determinant of persistent nasal Staphylococcus aureus carriage in humans?. J. Infect. Dis. 2010, 202:924-934.
    • (2010) J. Infect. Dis. , vol.202 , pp. 924-934
    • Ruimy, R.1
  • 29
    • 43049097482 scopus 로고    scopus 로고
    • Host polymorphisms in interleukin 4, complement factor H, and C-reactive protein associated with nasal carriage of Staphylococcus aureus and occurrence of boils
    • Emonts M., et al. Host polymorphisms in interleukin 4, complement factor H, and C-reactive protein associated with nasal carriage of Staphylococcus aureus and occurrence of boils. J. Infect. Dis. 2008, 197:1244-1253.
    • (2008) J. Infect. Dis. , vol.197 , pp. 1244-1253
    • Emonts, M.1
  • 30
    • 84876087956 scopus 로고    scopus 로고
    • Impaired β-defensin expression in human skin links DEFB1 promoter polymorphisms with persistent Staphylococcus aureus nasal carriage
    • Nurjadi D., et al. Impaired β-defensin expression in human skin links DEFB1 promoter polymorphisms with persistent Staphylococcus aureus nasal carriage. J. Infect. Dis. 2013, 207:666-674.
    • (2013) J. Infect. Dis. , vol.207 , pp. 666-674
    • Nurjadi, D.1
  • 31
    • 33745783528 scopus 로고    scopus 로고
    • Staphylococcus aureus nasal carriage is associated with glucocorticoid receptor gene polymorphisms
    • van den Akker E.L., et al. Staphylococcus aureus nasal carriage is associated with glucocorticoid receptor gene polymorphisms. J. Infect. Dis. 2006, 194:814-818.
    • (2006) J. Infect. Dis. , vol.194 , pp. 814-818
    • van den Akker, E.L.1
  • 32
    • 84908019081 scopus 로고    scopus 로고
    • Staphylococcus aureus nasal carriage might be associated with vitamin D receptor polymorphisms in type 2 diabetes
    • Messaritakis I., et al. Staphylococcus aureus nasal carriage might be associated with vitamin D receptor polymorphisms in type 2 diabetes. Clin. Microbiol. Infect. 2014, 20:920-925.
    • (2014) Clin. Microbiol. Infect. , vol.20 , pp. 920-925
    • Messaritakis, I.1
  • 33
    • 84905640294 scopus 로고    scopus 로고
    • Genome wide association study of SNP-, gene-, and pathway-based approaches to identify genes influencing susceptibility to Staphylococcus aureus Infection
    • Ye Z., et al. Genome wide association study of SNP-, gene-, and pathway-based approaches to identify genes influencing susceptibility to Staphylococcus aureus Infection. Front. Genet. 2014, 5:125.
    • (2014) Front. Genet. , vol.5 , pp. 125
    • Ye, Z.1
  • 34
    • 84893688185 scopus 로고    scopus 로고
    • A genome-wide association study of variants associated with acquisition of Staphylococcus aureus bacteremia in a health care setting
    • Nelson C.L., et al. A genome-wide association study of variants associated with acquisition of Staphylococcus aureus bacteremia in a health care setting. BMC Infect. Dis. 2014, 14:83.
    • (2014) BMC Infect. Dis. , vol.14 , pp. 83
    • Nelson, C.L.1
  • 35
    • 84895479892 scopus 로고    scopus 로고
    • A pooling-based genomewide association study identified genetic variants associated with Staphylococcus aureus colonization in chronic rhinosinusitis patients
    • Cormier C., et al. A pooling-based genomewide association study identified genetic variants associated with Staphylococcus aureus colonization in chronic rhinosinusitis patients. Int. Forum Allergy Rhinol. 2014, 4:207-215.
    • (2014) Int. Forum Allergy Rhinol. , vol.4 , pp. 207-215
    • Cormier, C.1
  • 36
    • 84877819839 scopus 로고    scopus 로고
    • XRN 5'-3' exoribonucleases: structure, mechanisms and functions
    • Nagarajan V.K., et al. XRN 5'-3' exoribonucleases: structure, mechanisms and functions. Biochem. Biophys. Acta 2013, 1829:590-603.
    • (2013) Biochem. Biophys. Acta , vol.1829 , pp. 590-603
    • Nagarajan, V.K.1
  • 37
    • 76749144053 scopus 로고    scopus 로고
    • Link of Dlk/ZIP kinase to cell apoptosis and tumor suppression
    • Wu Y., et al. Link of Dlk/ZIP kinase to cell apoptosis and tumor suppression. Biochem. Biophys. Res. Commun. 2010, 392:510-515.
    • (2010) Biochem. Biophys. Res. Commun. , vol.392 , pp. 510-515
    • Wu, Y.1
  • 38
    • 84877642787 scopus 로고    scopus 로고
    • Interaction of RhoD and ZIP kinase modulates actin filament assembly and focal adhesion dynamics
    • Nehru V., et al. Interaction of RhoD and ZIP kinase modulates actin filament assembly and focal adhesion dynamics. Biochem. Biophys. Res. Commun. 2013, 433:163-169.
    • (2013) Biochem. Biophys. Res. Commun. , vol.433 , pp. 163-169
    • Nehru, V.1
  • 39
    • 84897062118 scopus 로고    scopus 로고
    • Association of mannose-binding lectin 2 gene polymorphisms with persistent Staphylococcus aureus bacteremia
    • Chong Y.P., et al. Association of mannose-binding lectin 2 gene polymorphisms with persistent Staphylococcus aureus bacteremia. PLoS ONE 2014, 9:e89139.
    • (2014) PLoS ONE , vol.9 , pp. e89139
    • Chong, Y.P.1
  • 40
    • 0033754023 scopus 로고    scopus 로고
    • Cellular invasion by Staphylococcus aureus involves a fibronectin bridge between the bacterial fibronectin-binding MSCRAMMs and host cell beta1 integrins
    • Fowler T., et al. Cellular invasion by Staphylococcus aureus involves a fibronectin bridge between the bacterial fibronectin-binding MSCRAMMs and host cell beta1 integrins. Eur. J. Cell Biol. 2000, 79:672-679.
    • (2000) Eur. J. Cell Biol. , vol.79 , pp. 672-679
    • Fowler, T.1
  • 41
    • 84890235827 scopus 로고    scopus 로고
    • The interleukin-1 family: back to the future
    • Garlanda C., et al. The interleukin-1 family: back to the future. Immunity 2013, 39:1003-1018.
    • (2013) Immunity , vol.39 , pp. 1003-1018
    • Garlanda, C.1
  • 42
    • 84929504675 scopus 로고    scopus 로고
    • Toll-like receptor 2 and 6 interdependency in the erosive stage of Staphylococcus aureus induced septic arthritis mediated by IFN-g and IL-6 - A possible involvement of IL-17 in the progression of the disease
    • Ghosh C., Bishayi B. Toll-like receptor 2 and 6 interdependency in the erosive stage of Staphylococcus aureus induced septic arthritis mediated by IFN-g and IL-6 - A possible involvement of IL-17 in the progression of the disease. Immunobiology 2015, 220:910-923.
    • (2015) Immunobiology , vol.220 , pp. 910-923
    • Ghosh, C.1    Bishayi, B.2
  • 43
    • 84867733152 scopus 로고    scopus 로고
    • Elevated serum interleukin-10 (IL-10) at time of hospital admission is predictive of mortality in patients with Staphylococcus aureus bacteremia
    • Rose W.E., et al. Elevated serum interleukin-10 (IL-10) at time of hospital admission is predictive of mortality in patients with Staphylococcus aureus bacteremia. J. Infect. Dis. 2012, 206:1604-1611.
    • (2012) J. Infect. Dis. , vol.206 , pp. 1604-1611
    • Rose, W.E.1
  • 44
    • 84877786775 scopus 로고    scopus 로고
    • Inhibition of PDE4B suppresses inflammation by increasing expression of the deubiquitinase CYLD
    • Komatsu K., et al. Inhibition of PDE4B suppresses inflammation by increasing expression of the deubiquitinase CYLD. Nat. Commun. 2013, 4:1684.
    • (2013) Nat. Commun. , vol.4 , pp. 1684
    • Komatsu, K.1
  • 45
    • 84896542255 scopus 로고    scopus 로고
    • Neutral lipid stores and lipase PNPLA5 contribute to autophagosome biogenesis
    • Dupont N., et al. Neutral lipid stores and lipase PNPLA5 contribute to autophagosome biogenesis. Curr. Biol. 2014, 24:609-620.
    • (2014) Curr. Biol. , vol.24 , pp. 609-620
    • Dupont, N.1
  • 46
    • 77949885386 scopus 로고    scopus 로고
    • Nutritional immunity beyond iron: a role for manganese and zinc
    • Kehl-Fie T.E., Skaar E.P. Nutritional immunity beyond iron: a role for manganese and zinc. Curr. Opin. Chem. Biol. 2010, 14:218-224.
    • (2010) Curr. Opin. Chem. Biol. , vol.14 , pp. 218-224
    • Kehl-Fie, T.E.1    Skaar, E.P.2
  • 47
    • 0037502235 scopus 로고    scopus 로고
    • Bcl11b is required for differentiation and survival of alpha beta T lymphocytes
    • Wakabayashi Y., et al. Bcl11b is required for differentiation and survival of alpha beta T lymphocytes. Nat. Immunol. 2003, 4:533-539.
    • (2003) Nat. Immunol. , vol.4 , pp. 533-539
    • Wakabayashi, Y.1
  • 48
    • 84878359457 scopus 로고    scopus 로고
    • Vaccine review: "Staphylococcus aureus vaccines: Problems and prospects."
    • Jansen K.U., et al. Vaccine review: "Staphylococcus aureus vaccines: Problems and prospects.". Vaccine 2013, 31:2723-2730.
    • (2013) Vaccine , vol.31 , pp. 2723-2730
    • Jansen, K.U.1
  • 49
    • 0033522220 scopus 로고    scopus 로고
    • Hyper-IgE syndrome with recurrent infections - an autosomal dominant multisystem disorder
    • Grimbacher B., et al. Hyper-IgE syndrome with recurrent infections - an autosomal dominant multisystem disorder. N. Engl. J. Med. 1999, 340:692-702.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 692-702
    • Grimbacher, B.1
  • 50
    • 34548317417 scopus 로고    scopus 로고
    • Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper IgE syndrome
    • Minegishi Y., et al. Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper IgE syndrome. Nature 2007, 448:1058-1062.
    • (2007) Nature , vol.448 , pp. 1058-1062
    • Minegishi, Y.1
  • 51
    • 35348960378 scopus 로고    scopus 로고
    • STAT3 mutations in the Hyper-IgE syndrome
    • Holland S.M., et al. STAT3 mutations in the Hyper-IgE syndrome. N. Engl. J. Med. 2007, 357:1608-1619.
    • (2007) N. Engl. J. Med. , vol.357 , pp. 1608-1619
    • Holland, S.M.1
  • 52
    • 70949098060 scopus 로고    scopus 로고
    • Combined immunodeficiency associated with DOCK8 mutations
    • Zhang Q., et al. Combined immunodeficiency associated with DOCK8 mutations. N. Engl. J. Med. 2009, 361:2046-2055.
    • (2009) N. Engl. J. Med. , vol.361 , pp. 2046-2055
    • Zhang, Q.1
  • 53
    • 33845897463 scopus 로고    scopus 로고
    • Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity
    • Minegishi Y., et al. Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity. Immunity 2006, 25:745-755.
    • (2006) Immunity , vol.25 , pp. 745-755
    • Minegishi, Y.1
  • 55
    • 33846852867 scopus 로고    scopus 로고
    • Somatic revertant mosaicism in a patient with leukocyte adhesion deficiency type 1
    • Tone Y., et al. Somatic revertant mosaicism in a patient with leukocyte adhesion deficiency type 1. Blood 2007, 109:1182-1184.
    • (2007) Blood , vol.109 , pp. 1182-1184
    • Tone, Y.1
  • 56
    • 0035036072 scopus 로고    scopus 로고
    • Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency
    • Lubke T., et al. Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency. Nat. Genet. 2001, 28:73-76.
    • (2001) Nat. Genet. , vol.28 , pp. 73-76
    • Lubke, T.1
  • 57
    • 61949086409 scopus 로고    scopus 로고
    • Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation
    • Svensson L., et al. Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation. Nat. Med. 2009, 15:306-312.
    • (2009) Nat. Med. , vol.15 , pp. 306-312
    • Svensson, L.1
  • 58
    • 80054731104 scopus 로고    scopus 로고
    • Inflammatory skin and bowel disease linked to ADAM17 deletion
    • Blaydon D.C., et al. Inflammatory skin and bowel disease linked to ADAM17 deletion. N. Engl. J. Med. 2011, 365:1502-1508.
    • (2011) N. Engl. J. Med. , vol.365 , pp. 1502-1508
    • Blaydon, D.C.1
  • 59
    • 84871325751 scopus 로고    scopus 로고
    • Experimental and natural infections in MyD88- and IRAK-4-deficient mice and humans
    • Von Bermuth H., et al. Experimental and natural infections in MyD88- and IRAK-4-deficient mice and humans. Eur. J. Immunol. 2010, 42:3126-3135.
    • (2010) Eur. J. Immunol. , vol.42 , pp. 3126-3135
    • Von Bermuth, H.1
  • 60
    • 0033710565 scopus 로고    scopus 로고
    • Toxin in bullous impetigo and staphylococcal scaled-skin syndrome targets desmoglein 1
    • Amagai M., et al. Toxin in bullous impetigo and staphylococcal scaled-skin syndrome targets desmoglein 1. Nat. Med. 2000, 6:1275-1277.
    • (2000) Nat. Med. , vol.6 , pp. 1275-1277
    • Amagai, M.1
  • 61
    • 85047691609 scopus 로고    scopus 로고
    • Defining the pathogenic involvement of desmoglein 4 in pemphigus and staphylococcal scalded skin syndrome
    • Nagasaka T., et al. Defining the pathogenic involvement of desmoglein 4 in pemphigus and staphylococcal scalded skin syndrome. J. Clin. Invest. 2004, 114:1484-1492.
    • (2004) J. Clin. Invest. , vol.114 , pp. 1484-1492
    • Nagasaka, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.