Protein oxidation, nitration and glycation biomarkers for early-stage diagnosis of osteoarthritis of the knee and typing and progression of arthritic disease

Arthritis Research and Therapy

Volumn 18, Issue 1, 2016, Pages

  Ahmed, Usman ^a   Anwar, Attia ^a   Savage, Richard S ^b   Thornalley, Paul J ^a,b   Rabbani, Naila ^a,b  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

3 nitrotyrosine; Glycation; Machine learning; Osteoarthritis; Oxidative stress; Rheumatoid arthritis

Indexed keywords

AMINO ACID; BIOLOGICAL MARKER; CATABOLITE CONTROL PROTEIN ANTIBODY; HYDROXYPROLINE; PROTEIN; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

AREA UNDER THE CURVE; ARTICLE; CLASSIFICATION ALGORITHM; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE CLASSIFICATION; DISEASE COURSE; DISEASE SEVERITY; EARLY DIAGNOSIS; GLYCATION; HUMAN; INFLAMMATION; KNEE OSTEOARTHRITIS; LIQUID CHROMATOGRAPHY; MACHINE LEARNING; MAJOR CLINICAL STUDY; NITRATION; OXIDATION; PREDICTIVE VALUE; PROTEIN BLOOD LEVEL; PROTEIN OXIDATION; QUANTITATIVE ANALYSIS; RECEIVER OPERATING CHARACTERISTIC; RHEUMATOID ARTHRITIS; SENSITIVITY AND SPECIFICITY; SYNOVIAL FLUID; TANDEM MASS SPECTROMETRY; ADULT; AGED; ALGORITHM; BLOOD; FEMALE; MALE; METABOLISM; MIDDLE AGED; NITROSATION; OSTEOARTHRITIS, KNEE; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PROTEIN PROCESSING;

ADULT; AGED; ALGORITHMS; AMINO ACIDS; AREA UNDER CURVE; BIOMARKERS; CHROMATOGRAPHY, LIQUID; DISEASE PROGRESSION; EARLY DIAGNOSIS; FEMALE; HUMANS; MALE; MIDDLE AGED; NITROSATION; OSTEOARTHRITIS, KNEE; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEIN PROCESSING, POST-TRANSLATIONAL; ROC CURVE; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 84995814381     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/s13075-016-1154-3     Document Type: Article

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