A computational method to differentiate normal individuals, osteoarthritis and rheumatoid arthritis patients using serum biomarkers

Journal of the Royal Society Interface

Volumn 11, Issue 97, 2014, Pages

  Heard, Bryan J ^a,b   Rosvold, Joshua M ^a,b   Fritzler, Marvin J ^a   El Gabalawy, Hani ^c   Wiley, J Preston ^b   Krawetz, Roman J ^a,b  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

^c UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Artificial neural network; Cytokines; Diagnostic; Machine learning; Osteoarthritis; Serum

Indexed keywords

BODY FLUIDS; COMPLEX NETWORKS; DECISION TREES; DIAGNOSIS; DISEASES; LEARNING SYSTEMS; MOLECULAR BIOLOGY; NEURAL NETWORKS;

CYTOKINES; DECISION-TREE ALGORITHM; DIAGNOSTIC; INFLAMMATORY CYTOKINES; OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; SENSITIVITY AND SPECIFICITY; SERUM;

PROTEINS;

ALPHA2 INTERFERON; CD40 LIGAND; CYTOKINE; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; FLT3 LIGAND; FRACTALKINE; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 8; INTERLEUKIN 9; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MELANOMA GROWTH STIMULATORY ACTIVITY FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; VASCULOTROPIN; BIOLOGICAL MARKER;

ADULT; ALGORITHM; ARTICLE; ARTIFICIAL NEURAL NETWORK; COHORT ANALYSIS; CONTROLLED STUDY; DECISION TREE; HUMAN; MAJOR CLINICAL STUDY; OSTEOARTHRITIS; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SENSITIVITY AND SPECIFICITY; ARTHRITIS, RHEUMATOID; AUTOMATED PATTERN RECOGNITION; BLOOD; COMPUTER ASSISTED DIAGNOSIS; FEMALE; MALE; MIDDLE AGED; PROCEDURES; REFERENCE VALUE; REPRODUCIBILITY;

ADULT; ALGORITHMS; ARTHRITIS, RHEUMATOID; BIOLOGICAL MARKERS; CYTOKINES; DIAGNOSIS, COMPUTER-ASSISTED; FEMALE; HUMANS; MALE; MIDDLE AGED; NEURAL NETWORKS (COMPUTER); OSTEOARTHRITIS; PATTERN RECOGNITION, AUTOMATED; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 84903641352     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2014.0428     Document Type: Article

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