메뉴 건너뛰기




Volumn 60, Issue 2, 2017, Pages 354-363

Circulating microRNA levels predict residual beta cell function and glycaemic control in children with type 1 diabetes mellitus

Author keywords

Biomarkers; Children; miRNA; Residual beta cell function

Indexed keywords

C PEPTIDE; GONADORELIN RECEPTOR; HEMOGLOBIN A1C; MICRORNA; GLUCOSE BLOOD LEVEL; MIRN146 MICRORNA, HUMAN; MIRN194 MICRORNA, HUMAN; MIRN24 MICRORNA, HUMAN; MIRN375 MICRORNA, HUMAN;

EID: 84995810319     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-016-4156-4     Document Type: Article
Times cited : (61)

References (45)
  • 1
    • 81355142141 scopus 로고    scopus 로고
    • Non-coding RNAs in human disease
    • COI: 1:CAS:528:DC%2BC3MXhsVyktrfL, PID: 22094949
    • Esteller M (2011) Non-coding RNAs in human disease. Nat Rev Genet 12:861–874
    • (2011) Nat Rev Genet , vol.12 , pp. 861-874
    • Esteller, M.1
  • 2
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • COI: 1:CAS:528:DC%2BD1MXhs1Kiuro%3D, PID: 19167326
    • Bartel DP (2009) MicroRNAs: target recognition and regulatory functions. Cell 136:215–233
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 3
    • 0036544755 scopus 로고    scopus 로고
    • Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation
    • COI: 1:CAS:528:DC%2BD38Xisl2lsL8%3D, PID: 11896390
    • Lai EC (2002) Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation. Nat Genet 30:363–364
    • (2002) Nat Genet , vol.30 , pp. 363-364
    • Lai, E.C.1
  • 4
    • 77955644289 scopus 로고    scopus 로고
    • Mammalian microRNAs predominantly act to decrease target mRNA levels
    • COI: 1:CAS:528:DC%2BC3cXhtVais7nN, PID: 20703300
    • Guo H, Ingolia NT, Weissman JS, Bartel DP (2010) Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466:835–840
    • (2010) Nature , vol.466 , pp. 835-840
    • Guo, H.1    Ingolia, N.T.2    Weissman, J.S.3    Bartel, D.P.4
  • 6
    • 84930396449 scopus 로고    scopus 로고
    • MicroRNA regulation of lymphocyte tolerance and autoimmunity
    • PID: 26030228
    • Simpson LJ, Ansel KM (2015) MicroRNA regulation of lymphocyte tolerance and autoimmunity. J Clin Invest 125:2242–2249
    • (2015) J Clin Invest , vol.125 , pp. 2242-2249
    • Simpson, L.J.1    Ansel, K.M.2
  • 7
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • COI: 1:CAS:528:DC%2BD2sXmtVSmtb8%3D, PID: 17486113
    • Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO (2007) Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol 9:654–659
    • (2007) Nat Cell Biol , vol.9 , pp. 654-659
    • Valadi, H.1    Ekstrom, K.2    Bossios, A.3    Sjostrand, M.4    Lee, J.J.5    Lotvall, J.O.6
  • 8
    • 80052381608 scopus 로고    scopus 로고
    • Characterization of extracellular circulating microRNA
    • COI: 1:CAS:528:DC%2BC3MXhtFehtr%2FE, PID: 21609964
    • Turchinovich A, Weiz L, Langheinz A, Burwinkel B (2011) Characterization of extracellular circulating microRNA. Nucleic Acids Res 39:7223–7233
    • (2011) Nucleic Acids Res , vol.39 , pp. 7223-7233
    • Turchinovich, A.1    Weiz, L.2    Langheinz, A.3    Burwinkel, B.4
  • 9
    • 0035856952 scopus 로고    scopus 로고
    • beta-Cell death during progression to diabetes
    • COI: 1:CAS:528:DC%2BD38Xhtlymug%3D%3D, PID: 11742411
    • Mathis D, Vence L, Benoist C (2001) beta-Cell death during progression to diabetes. Nature 414:792–798
    • (2001) Nature , vol.414 , pp. 792-798
    • Mathis, D.1    Vence, L.2    Benoist, C.3
  • 10
    • 84885861691 scopus 로고    scopus 로고
    • Do post-translational beta cell protein modifications trigger type 1 diabetes?
    • PID: 24048671
    • Storling J, Overgaard AJ, Brorsson CA et al (2013) Do post-translational beta cell protein modifications trigger type 1 diabetes? Diabetologia 56:2347–2354
    • (2013) Diabetologia , vol.56 , pp. 2347-2354
    • Storling, J.1    Overgaard, A.J.2    Brorsson, C.A.3
  • 12
    • 84888156471 scopus 로고    scopus 로고
    • Identifying common and specific microRNAs expressed in peripheral blood mononuclear cell of type 1, type 2, and gestational diabetes mellitus patients
    • PID: 24279768
    • Collares CV, Evangelista AF, Xavier DJ et al (2013) Identifying common and specific microRNAs expressed in peripheral blood mononuclear cell of type 1, type 2, and gestational diabetes mellitus patients. BMC Res Notes 6:491
    • (2013) BMC Res Notes , vol.6 , pp. 491
    • Collares, C.V.1    Evangelista, A.F.2    Xavier, D.J.3
  • 13
    • 84864981566 scopus 로고    scopus 로고
    • Circulating levels of microRNA from children with newly diagnosed type 1 diabetes and healthy controls: evidence that miR-25 associates to residual beta-cell function and glycaemic control during disease progression
    • PID: 22829805
    • Nielsen LB, Wang C, Sorensen K et al (2012) Circulating levels of microRNA from children with newly diagnosed type 1 diabetes and healthy controls: evidence that miR-25 associates to residual beta-cell function and glycaemic control during disease progression. Exp Diabetes Res 2012:896362
    • (2012) Exp Diabetes Res , vol.2012 , pp. 896362
    • Nielsen, L.B.1    Wang, C.2    Sorensen, K.3
  • 14
    • 84948783440 scopus 로고    scopus 로고
    • MicroRNAs as regulators of beta-cell function and dysfunction
    • COI: 1:CAS:528:DC%2BC28Xmt12ltrs%3D, PID: 26418758
    • Osmai M, Osmai Y, Bang-Berthelsen CH et al (2016) MicroRNAs as regulators of beta-cell function and dysfunction. Diabetes Metab Res Rev 32:334–349
    • (2016) Diabetes Metab Res Rev , vol.32 , pp. 334-349
    • Osmai, M.1    Osmai, Y.2    Bang-Berthelsen, C.H.3
  • 15
    • 84896715542 scopus 로고    scopus 로고
    • MicroRNA expression profiling and functional annotation analysis of their targets in patients with type 1 diabetes mellitus
    • COI: 1:CAS:528:DC%2BC2cXjt1Wmur8%3D, PID: 24530307
    • Takahashi P, Xavier DJ, Evangelista AF et al (2014) MicroRNA expression profiling and functional annotation analysis of their targets in patients with type 1 diabetes mellitus. Gene 539:213–223
    • (2014) Gene , vol.539 , pp. 213-223
    • Takahashi, P.1    Xavier, D.J.2    Evangelista, A.F.3
  • 16
    • 84906086651 scopus 로고    scopus 로고
    • Molecular signatures differentiate immune states in type 1 diabetic families
    • COI: 1:CAS:528:DC%2BC2cXhvVygsr3I, PID: 24760139
    • Chen YG, Cabrera SM, Jia S et al (2014) Molecular signatures differentiate immune states in type 1 diabetic families. Diabetes 63:3960–3973
    • (2014) Diabetes , vol.63 , pp. 3960-3973
    • Chen, Y.G.1    Cabrera, S.M.2    Jia, S.3
  • 17
    • 84907211338 scopus 로고    scopus 로고
    • Diabetes-associated microRNAs in pediatric patients with type 1 diabetes mellitus: a cross-sectional cohort study
    • COI: 1:CAS:528:DC%2BC2cXhs1enurvE, PID: 24937532
    • Osipova J, Fischer DC, Dangwal S et al (2014) Diabetes-associated microRNAs in pediatric patients with type 1 diabetes mellitus: a cross-sectional cohort study. J Clin Endocrinol Metab 99:E1661–E1665
    • (2014) J Clin Endocrinol Metab , vol.99 , pp. E1661-E1665
    • Osipova, J.1    Fischer, D.C.2    Dangwal, S.3
  • 18
    • 84935874558 scopus 로고    scopus 로고
    • Epigenetic changes in endothelial progenitors as a possible cellular basis for glycemic memory in diabetic vascular complications
    • PID: 26106624
    • Rajasekar P, O’Neill CL, Eeles L, Stitt AW, Medina RJ (2015) Epigenetic changes in endothelial progenitors as a possible cellular basis for glycemic memory in diabetic vascular complications. J Diabetes Res 2015:436879
    • (2015) J Diabetes Res , vol.2015 , pp. 436879
    • Rajasekar, P.1    O’Neill, C.L.2    Eeles, L.3    Stitt, A.W.4    Medina, R.J.5
  • 19
    • 84907190421 scopus 로고    scopus 로고
    • Plasma exosome microRNA profiling unravels a new potential modulator of adiponectin pathway in diabetes: effect of glycemic control
    • COI: 1:CAS:528:DC%2BC2cXhs1enurjO, PID: 24937531
    • Santovito D, De Nardis V, Marcantonio P et al (2014) Plasma exosome microRNA profiling unravels a new potential modulator of adiponectin pathway in diabetes: effect of glycemic control. J Clin Endocrinol Metab 99:E1681–E1685
    • (2014) J Clin Endocrinol Metab , vol.99 , pp. E1681-E1685
    • Santovito, D.1    De Nardis, V.2    Marcantonio, P.3
  • 20
    • 84878748010 scopus 로고    scopus 로고
    • Complex multi-block analysis identifies new immunologic and genetic disease progression patterns associated with the residual beta-cell function 1 year after diagnosis of type 1 diabetes
    • PID: 23755131
    • Andersen ML, Rasmussen MA, Porksen S et al (2013) Complex multi-block analysis identifies new immunologic and genetic disease progression patterns associated with the residual beta-cell function 1 year after diagnosis of type 1 diabetes. PLoS One 8, e64632
    • (2013) PLoS One , vol.8
    • Andersen, M.L.1    Rasmussen, M.A.2    Porksen, S.3
  • 21
    • 84925465190 scopus 로고    scopus 로고
    • The influence of glucagon on postprandial hyperglycaemia in children 5 years after onset of type 1 diabetes
    • COI: 1:CAS:528:DC%2BC2MXhtFGgu78%3D, PID: 25541633
    • Fredheim S, Andersen ML, Porksen S et al (2015) The influence of glucagon on postprandial hyperglycaemia in children 5 years after onset of type 1 diabetes. Diabetologia 58:828–834
    • (2015) Diabetologia , vol.58 , pp. 828-834
    • Fredheim, S.1    Andersen, M.L.2    Porksen, S.3
  • 22
    • 68149136902 scopus 로고    scopus 로고
    • New definition for the partial remission period in children and adolescents with type 1 diabetes
    • COI: 1:CAS:528:DC%2BD1MXhtV2gsL7J, PID: 19435955
    • Mortensen HB, Hougaard P, Swift P et al (2009) New definition for the partial remission period in children and adolescents with type 1 diabetes. Diabetes Care 32:1384–1390
    • (2009) Diabetes Care , vol.32 , pp. 1384-1390
    • Mortensen, H.B.1    Hougaard, P.2    Swift, P.3
  • 23
    • 77954518961 scopus 로고    scopus 로고
    • Multinational study in children and adolescents with newly diagnosed type 1 diabetes: association of age, ketoacidosis, HLA status, and autoantibodies on residual beta-cell function and glycemic control 12 months after diagnosis
    • COI: 1:CAS:528:DC%2BC3cXptFymtrY%3D, PID: 19708904
    • Mortensen HB, Swift PG, Holl RW et al (2010) Multinational study in children and adolescents with newly diagnosed type 1 diabetes: association of age, ketoacidosis, HLA status, and autoantibodies on residual beta-cell function and glycemic control 12 months after diagnosis. Pediatr Diabetes 11:218–226
    • (2010) Pediatr Diabetes , vol.11 , pp. 218-226
    • Mortensen, H.B.1    Swift, P.G.2    Holl, R.W.3
  • 24
    • 85007311273 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications: report of a WHO consultation. Part 1. Diagnosis and classification of diabetes mellitus
    • World Health Organization (1999) Definition, diagnosis and classification of diabetes mellitus and its complications: report of a WHO consultation. Part 1. Diagnosis and classification of diabetes mellitus. Available from http://apps.who.int/iris/handle/10665/66040. Accessed 1 April 2016
    • (1999) Available from
  • 25
    • 84876386633 scopus 로고    scopus 로고
    • Assessing sample and miRNA profile quality in serum and plasma or other biofluids
    • COI: 1:CAS:528:DC%2BC38XhsFKnsb3I, PID: 23036329
    • Blondal T, Jensby Nielsen S, Baker A et al (2013) Assessing sample and miRNA profile quality in serum and plasma or other biofluids. Methods 59:S1–S6
    • (2013) Methods , vol.59 , pp. S1-S6
    • Blondal, T.1    Jensby Nielsen, S.2    Baker, A.3
  • 26
    • 67649729608 scopus 로고    scopus 로고
    • A novel and universal method for microRNA RT-qPCR data normalization
    • PID: 19531210
    • Mestdagh P, Van Vlierberghe P, De Weer A et al (2009) A novel and universal method for microRNA RT-qPCR data normalization. Genome Biol 10:R64
    • (2009) Genome Biol , vol.10 , pp. R64
    • Mestdagh, P.1    Van Vlierberghe, P.2    De Weer, A.3
  • 27
    • 33645762226 scopus 로고
    • A sharper Bonferroni procedure for multiple tests of significance
    • Hochberg Y (1988) A sharper Bonferroni procedure for multiple tests of significance. Biometrika 75:800–802
    • (1988) Biometrika , vol.75 , pp. 800-802
    • Hochberg, Y.1
  • 28
    • 79959805164 scopus 로고    scopus 로고
    • miRWalk–database: prediction of possible miRNA binding sites by “walking” the genes of three genomes
    • COI: 1:CAS:528:DC%2BC3MXhtF2jt7nO, PID: 21605702
    • Dweep H, Sticht C, Pandey P, Gretz N (2011) miRWalk–database: prediction of possible miRNA binding sites by “walking” the genes of three genomes. J Biomed Inform 44:839–847
    • (2011) J Biomed Inform , vol.44 , pp. 839-847
    • Dweep, H.1    Sticht, C.2    Pandey, P.3    Gretz, N.4
  • 29
    • 84976904131 scopus 로고    scopus 로고
    • miRTarBase 2016: updates to the experimentally validated miRNA-target interactions database
    • PID: 26590260
    • Chou CH, Chang NW, Shrestha S et al (2016) miRTarBase 2016: updates to the experimentally validated miRNA-target interactions database. Nucleic Acids Res 44:D239–D247
    • (2016) Nucleic Acids Res , vol.44 , pp. D239-D247
    • Chou, C.H.1    Chang, N.W.2    Shrestha, S.3
  • 30
    • 84891818924 scopus 로고    scopus 로고
    • starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data
    • COI: 1:CAS:528:DC%2BC2cXos1ar, PID: 24297251
    • Li JH, Liu S, Zhou H, Qu LH, Yang JH (2014) starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data. Nucleic Acids Res 42:D92–D97
    • (2014) Nucleic Acids Res , vol.42 , pp. D92-D97
    • Li, J.H.1    Liu, S.2    Zhou, H.3    Qu, L.H.4    Yang, J.H.5
  • 31
    • 0033982936 scopus 로고    scopus 로고
    • KEGG: Kyoto Encyclopedia of Genes and Genomes
    • COI: 1:CAS:528:DC%2BD3cXhvVGqu74%3D, PID: 10592173
    • Kanehisa M, Goto S (2000) KEGG: Kyoto Encyclopedia of Genes and Genomes. Nucleic Acids Res 28:27–30
    • (2000) Nucleic Acids Res , vol.28 , pp. 27-30
    • Kanehisa, M.1    Goto, S.2
  • 32
    • 84892511644 scopus 로고    scopus 로고
    • Large-scale gene function analysis with the PANTHER classification system
    • PID: 23868073
    • Mi H, Muruganujan A, Casagrande JT, Thomas PD (2013) Large-scale gene function analysis with the PANTHER classification system. Nat Protoc 8:1551–1566
    • (2013) Nat Protoc , vol.8 , pp. 1551-1566
    • Mi, H.1    Muruganujan, A.2    Casagrande, J.T.3    Thomas, P.D.4
  • 33
    • 77957259803 scopus 로고    scopus 로고
    • Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes
    • COI: 1:CAS:528:DC%2BC3cXhtFOktrjI, PID: 20651284
    • Zampetaki A, Kiechl S, Drozdov I et al (2010) Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes. Circ Res 107:810–817
    • (2010) Circ Res , vol.107 , pp. 810-817
    • Zampetaki, A.1    Kiechl, S.2    Drozdov, I.3
  • 34
    • 84863181834 scopus 로고    scopus 로고
    • Research resource: the pdx1 cistrome of pancreatic islets
    • COI: 1:CAS:528:DC%2BC38XjvVaqtr8%3D, PID: 22322596
    • Khoo C, Yang J, Weinrott SA et al (2012) Research resource: the pdx1 cistrome of pancreatic islets. Mol Endocrinol 26:521–533
    • (2012) Mol Endocrinol , vol.26 , pp. 521-533
    • Khoo, C.1    Yang, J.2    Weinrott, S.A.3
  • 35
    • 78149250620 scopus 로고    scopus 로고
    • AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through activation of the pro-apoptotic Bcl-2 homology domain-3-only protein BMF
    • COI: 1:CAS:528:DC%2BC3cXhtlyntb3M, PID: 20841353
    • Kilbride SM, Farrelly AM, Bonner C et al (2010) AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through activation of the pro-apoptotic Bcl-2 homology domain-3-only protein BMF. J Biol Chem 285:36199–36206
    • (2010) J Biol Chem , vol.285 , pp. 36199-36206
    • Kilbride, S.M.1    Farrelly, A.M.2    Bonner, C.3
  • 36
    • 84880908319 scopus 로고    scopus 로고
    • MicroRNA regulate immune pathways in T cells in multiple sclerosis (MS)
    • PID: 23895517
    • Jernas M, Malmestrom C, Axelsson M et al (2013) MicroRNA regulate immune pathways in T cells in multiple sclerosis (MS). BMC Immunol 14:32
    • (2013) BMC Immunol , vol.14 , pp. 32
    • Jernas, M.1    Malmestrom, C.2    Axelsson, M.3
  • 37
    • 84924928436 scopus 로고    scopus 로고
    • miRNAs affect the expression of innate and adaptive immunity proteins in celiac disease
    • COI: 1:CAS:528:DC%2BC2cXhslartLnJ, PID: 25070052
    • Magni S, Buoli Comani G, Elli L et al (2014) miRNAs affect the expression of innate and adaptive immunity proteins in celiac disease. Am J Gastroenterol 109:1662–1674
    • (2014) Am J Gastroenterol , vol.109 , pp. 1662-1674
    • Magni, S.1    Buoli Comani, G.2    Elli, L.3
  • 38
    • 84927930174 scopus 로고    scopus 로고
    • Aberrant expression of miRNA and mRNAs in lesioned tissues of Graves’ disease
    • COI: 1:CAS:528:DC%2BC2MXnsVWjtb0%3D, PID: 25871842
    • Qin Q, Wang X, Yan N et al (2015) Aberrant expression of miRNA and mRNAs in lesioned tissues of Graves’ disease. Cell Physiol Biochem 35:1934–1942
    • (2015) Cell Physiol Biochem , vol.35 , pp. 1934-1942
    • Qin, Q.1    Wang, X.2    Yan, N.3
  • 39
    • 84870746025 scopus 로고    scopus 로고
    • Circulating miRNA profiles in patients with metabolic syndrome
    • COI: 1:CAS:528:DC%2BC38XhvVCgtLzI, PID: 23032062
    • Karolina DS, Tavintharan S, Armugam A et al (2012) Circulating miRNA profiles in patients with metabolic syndrome. J Clin Endocrinol Metab 97:E2271–E2276
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. E2271-E2276
    • Karolina, D.S.1    Tavintharan, S.2    Armugam, A.3
  • 40
    • 58149350343 scopus 로고    scopus 로고
    • miR-375 targets 3′-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells
    • PID: 18591395
    • El Ouaamari A, Baroukh N, Martens GA, Lebrun P, Pipeleers D, van Obberghen E (2008) miR-375 targets 3′-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells. Diabetes 57:2708–2717
    • (2008) Diabetes , vol.57 , pp. 2708-2717
    • El Ouaamari, A.1    Baroukh, N.2    Martens, G.A.3    Lebrun, P.4    Pipeleers, D.5    van Obberghen, E.6
  • 41
    • 79952259862 scopus 로고    scopus 로고
    • miRNAs control insulin content in pancreatic beta-cells via downregulation of transcriptional repressors
    • COI: 1:CAS:528:DC%2BC3MXhtlektrw%3D, PID: 21285947
    • Melkman-Zehavi T, Oren R, Kredo-Russo S et al (2011) miRNAs control insulin content in pancreatic beta-cells via downregulation of transcriptional repressors. EMBO J 30:835–845
    • (2011) EMBO J , vol.30 , pp. 835-845
    • Melkman-Zehavi, T.1    Oren, R.2    Kredo-Russo, S.3
  • 42
    • 84928901831 scopus 로고    scopus 로고
    • MiR-375 promotes redifferentiation of adult human beta cells expanded in vitro
    • PID: 25875172
    • Nathan G, Kredo-Russo S, Geiger T et al (2015) MiR-375 promotes redifferentiation of adult human beta cells expanded in vitro. PLoS One 10, e0122108
    • (2015) PLoS One , vol.10
    • Nathan, G.1    Kredo-Russo, S.2    Geiger, T.3
  • 43
    • 12144279068 scopus 로고    scopus 로고
    • Nuclear factor-{kappa}B activity in {beta}-cells is required for glucose-stimulated insulin secretion
    • COI: 1:CAS:528:DC%2BD2MXhtVWju7o%3D, PID: 15616019
    • Norlin S, Ahlgren U, Edlund H (2005) Nuclear factor-{kappa}B activity in {beta}-cells is required for glucose-stimulated insulin secretion. Diabetes 54:125–132
    • (2005) Diabetes , vol.54 , pp. 125-132
    • Norlin, S.1    Ahlgren, U.2    Edlund, H.3
  • 44
    • 65249093130 scopus 로고    scopus 로고
    • miR-375 maintains normal pancreatic alpha- and beta-cell mass
    • COI: 1:CAS:528:DC%2BD1MXkvFagt7c%3D, PID: 19289822
    • Poy MN, Hausser J, Trajkovski M et al (2009) miR-375 maintains normal pancreatic alpha- and beta-cell mass. Proc Natl Acad Sci U S A 106:5813–5818
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 5813-5818
    • Poy, M.N.1    Hausser, J.2    Trajkovski, M.3
  • 45
    • 84930016720 scopus 로고    scopus 로고
    • miR-194 Promotes burn-induced hyperglycemia via attenuating IGF-IR expression
    • COI: 1:CAS:528:DC%2BC2cXhvFGnsrzK, PID: 25186839
    • Yu Y, Chai J, Zhang H et al (2014) miR-194 Promotes burn-induced hyperglycemia via attenuating IGF-IR expression. Shock 42:578–584
    • (2014) Shock , vol.42 , pp. 578-584
    • Yu, Y.1    Chai, J.2    Zhang, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.