-
1
-
-
31444455909
-
Expansion and redifferentiation of adult human pancreatic islet cells
-
PMID: 16446152
-
Ouziel-Yahalom L, Zalzman M, Anker-Kitai L, Knoller S, Bar Y, Glandt M, et al. (2006) Expansion and redifferentiation of adult human pancreatic islet cells. Biochem Biophys Res Commun 341: 291-298. PMID: 16446152
-
(2006)
Biochem Biophys Res Commun
, vol.341
, pp. 291-298
-
-
Ouziel-Yahalom, L.1
Zalzman, M.2
Anker-Kitai, L.3
Knoller, S.4
Bar, Y.5
Glandt, M.6
-
2
-
-
44749087001
-
In vitro proliferation of cells derived from adult human beta-cells revealed by cell-lineage tracing
-
PMID: 18316362
-
Russ HA, Bar Y, Ravassard P, Efrat S (2008) In vitro proliferation of cells derived from adult human beta-cells revealed by cell-lineage tracing. Diabetes 57: 1575-1583. doi: 10.2337/db07-1283 PMID: 18316362
-
(2008)
Diabetes
, vol.57
, pp. 1575-1583
-
-
Russ, H.A.1
Bar, Y.2
Ravassard, P.3
Efrat, S.4
-
3
-
-
68149156892
-
Epithelial-mesenchymal transition in cells expanded in vitro from lineage-traced adult human pancreatic beta cells
-
PMID: 19641613
-
Russ HA, Ravassard P, Kerr-Conte J, Pattou F, Efrat S (2009) Epithelial-mesenchymal transition in cells expanded in vitro from lineage-traced adult human pancreatic beta cells. PLoS One 4: e6417. doi: 10.1371/journal.pone.0006417 PMID: 19641613
-
(2009)
PLoS One
, vol.4
, pp. e6417
-
-
Russ, H.A.1
Ravassard, P.2
Kerr-Conte, J.3
Pattou, F.4
Efrat, S.5
-
4
-
-
79959992876
-
Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells
-
PMID: 21726830
-
Bar-Nur O, Russ HA, Efrat S, Benvenisty N (2011) Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells. Cell Stem Cell 9: 17-23. doi: 10.1016/j.stem.2011.06.007 PMID: 21726830
-
(2011)
Cell Stem Cell
, vol.9
, pp. 17-23
-
-
Bar-Nur, O.1
Russ, H.A.2
Efrat, S.3
Benvenisty, N.4
-
5
-
-
80053608936
-
Insulin-producing cells generated from dedifferentiated human pancreatic beta cells expanded in vitro
-
PMID: 21984932
-
Russ HA, Sintov E, Anker-Kitai L, Friedman O, Lenz A, Toren G, et al. (2011) Insulin-producing cells generated from dedifferentiated human pancreatic beta cells expanded in vitro. PLoS One 6: e25566. doi: 10.1371/journal.pone.0025566 PMID: 21984932
-
(2011)
PLoS One
, vol.6
, pp. e25566
-
-
Russ, H.A.1
Sintov, E.2
Anker-Kitai, L.3
Friedman, O.4
Lenz, A.5
Toren, G.6
-
6
-
-
77953629046
-
Regulation of mRNA translation and stability by microRNAs
-
PMID: 20533884
-
Fabian MR, Sonenberg N, FilipowiczW(2010) Regulation of mRNA translation and stability by microRNAs. Annu Rev Biochem 79: 351-379. doi: 10.1146/annurev-biochem-060308-103103 PMID: 20533884
-
(2010)
Annu Rev Biochem
, vol.79
, pp. 351-379
-
-
Fabian, M.R.1
Sonenberg, N.2
Filipowicz, W.3
-
7
-
-
36248978699
-
MicroRNA expression is required for pancreatic islet cell genesis in the mouse
-
PMID: 17804764
-
Lynn FC, Skewes-Cox P, Kosaka Y, McManus MT, Harfe BD, German MS (2007) MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes 56: 2938-2945. PMID: 17804764
-
(2007)
Diabetes
, vol.56
, pp. 2938-2945
-
-
Lynn, F.C.1
Skewes-Cox, P.2
Kosaka, Y.3
McManus, M.T.4
Harfe, B.D.5
German, M.S.6
-
8
-
-
9144270691
-
A pancreatic islet-specific microRNA regulates insulin secretion
-
PMID: 15538371
-
Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, et al. (2004) A pancreatic islet-specific microRNA regulates insulin secretion. Nature 432: 226-230. PMID: 15538371
-
(2004)
Nature
, vol.432
, pp. 226-230
-
-
Poy, M.N.1
Eliasson, L.2
Krutzfeldt, J.3
Kuwajima, S.4
Ma, X.5
Macdonald, P.E.6
-
9
-
-
84891856209
-
Epigenetic regulation of the DLK1-MEG3 microRNA cluster in human type 2 diabetic islets
-
PMID: 24374217
-
Kameswaran V, Bramswig NC, McKenna LB, Penn M, Schug J, Hand NJ, et al. (2014) Epigenetic regulation of the DLK1-MEG3 microRNA cluster in human type 2 diabetic islets. Cell Metab 19: 135-145. doi: 10.1016/j.cmet.2013.11.016 PMID: 24374217
-
(2014)
Cell Metab
, vol.19
, pp. 135-145
-
-
Kameswaran, V.1
Bramswig, N.C.2
McKenna, L.B.3
Penn, M.4
Schug, J.5
Hand, N.J.6
-
10
-
-
65249093130
-
miR-375 maintains normal pancreatic alpha- and beta-cell mass
-
PMID: 19289822
-
Poy MN, Hausser J, Trajkovski M, Braun M, Collins S, Rorsman P, et al. (2009) miR-375 maintains normal pancreatic alpha- and beta-cell mass. Proc Natl Acad Sci U S A 106: 5813-5818. doi: 10.1073/pnas.0810550106 PMID: 19289822
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 5813-5818
-
-
Poy, M.N.1
Hausser, J.2
Trajkovski, M.3
Braun, M.4
Collins, S.5
Rorsman, P.6
-
11
-
-
22044458072
-
MicroRNA expression in zebrafish embryonic development
-
PMID: 15919954
-
Wienholds E, Kloosterman WP, Miska E, Alvarez-Saavedra E, Berezikov E, de Bruijn E, et al. (2005) MicroRNA expression in zebrafish embryonic development. Science 309: 310-311. PMID: 15919954
-
(2005)
Science
, vol.309
, pp. 310-311
-
-
Wienholds, E.1
Kloosterman, W.P.2
Miska, E.3
Alvarez-Saavedra, E.4
Berezikov, E.5
De Bruijn, E.6
-
12
-
-
58149473947
-
Expression of islet-specific microRNAs during human pancreatic development
-
PMID: 18977315
-
Joglekar MV, Joglekar VM, Hardikar AA (2009) Expression of islet-specific microRNAs during human pancreatic development. Gene Expr Patterns 9: 109-113. doi: 10.1016/j.gep.2008.10.001 PMID: 18977315
-
(2009)
Gene Expr Patterns
, vol.9
, pp. 109-113
-
-
Joglekar, M.V.1
Joglekar, V.M.2
Hardikar, A.A.3
-
13
-
-
79952259862
-
miRNAs control insulin content in pancreatic beta-cells via downregulation of transcriptional repressors
-
PMID: 21285947
-
Melkman-Zehavi T, Oren R, Kredo-Russo S, Shapira T, Mandelbaum AD, Rivkin N, et al. (2011) miRNAs control insulin content in pancreatic beta-cells via downregulation of transcriptional repressors. EMBO J 30: 835-845. doi: 10.1038/emboj.2010.361 PMID: 21285947
-
(2011)
EMBO J
, vol.30
, pp. 835-845
-
-
Melkman-Zehavi, T.1
Oren, R.2
Kredo-Russo, S.3
Shapira, T.4
Mandelbaum, A.D.5
Rivkin, N.6
-
14
-
-
84873815396
-
MicroRNA expression in alpha and beta cells of human pancreatic islets
-
PMID: 23383059
-
Klein D, Misawa R, Bravo-Egana V, Vargas N, Rosero S, Piroso J, et al. (2013) MicroRNA expression in alpha and beta cells of human pancreatic islets. PLoS One 8: e55064. doi: 10.1371/journal.pone.0055064 PMID: 23383059
-
(2013)
PLoS One
, vol.8
, pp. e55064
-
-
Klein, D.1
Misawa, R.2
Bravo-Egana, V.3
Vargas, N.4
Rosero, S.5
Piroso, J.6
-
15
-
-
13944260434
-
Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes
-
PMID: 15701730
-
Baskerville S, Bartel DP (2005) Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes. RNA 11: 241-247. PMID: 15701730
-
(2005)
RNA
, vol.11
, pp. 241-247
-
-
Baskerville, S.1
Bartel, D.P.2
-
16
-
-
38449091863
-
Detection of microRNAs in frozen tissue sections by fluorescence in situ hybridization using locked nucleic acid probes and tyramide signal amplification
-
PMID: 17947994
-
Silahtaroglu AN, Nolting D, Dyrskjot L, Berezikov E, Moller M, Tommerup N, et al. (2007) Detection of microRNAs in frozen tissue sections by fluorescence in situ hybridization using locked nucleic acid probes and tyramide signal amplification. Nat Protoc 2: 2520-2528. PMID: 17947994
-
(2007)
Nat Protoc
, vol.2
, pp. 2520-2528
-
-
Silahtaroglu, A.N.1
Nolting, D.2
Dyrskjot, L.3
Berezikov, E.4
Moller, M.5
Tommerup, N.6
-
17
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
PMID: 18376396
-
Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G, et al. (2008) The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 10: 593-601. doi: 10.1038/ncb1722 PMID: 18376396
-
(2008)
Nat Cell Biol
, vol.10
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.G.2
Paterson, E.L.3
Barry, S.C.4
Tsykin, A.5
Farshid, G.6
-
18
-
-
79951705428
-
The miR-30 family microRNAs confer epithelial phenotype to human pancreatic cells
-
PMID: 21099261
-
Joglekar MV, Patil D, Joglekar VM, Rao G, Reddy DN, Mitnala S, et al. (2009) The miR-30 family microRNAs confer epithelial phenotype to human pancreatic cells. Islets 1: 137-147. doi: 10.4161/isl.1.2.9578 PMID: 21099261
-
(2009)
Islets
, vol.1
, pp. 137-147
-
-
Joglekar, M.V.1
Patil, D.2
Joglekar, V.M.3
Rao, G.4
Reddy, D.N.5
Mitnala, S.6
-
19
-
-
84864305807
-
Pancreas-enriched miRNA refines endocrine cell differentiation
-
PMID: 22764048
-
Kredo-Russo S, Mandelbaum AD, Ness A, Alon I, Lennox KA, Behlke MA, et al. (2012) Pancreas-enriched miRNA refines endocrine cell differentiation. Development 139: 3021-3031. doi: 10.1242/dev.080127 PMID: 22764048
-
(2012)
Development
, vol.139
, pp. 3021-3031
-
-
Kredo-Russo, S.1
Mandelbaum, A.D.2
Ness, A.3
Alon, I.4
Lennox, K.A.5
Behlke, M.A.6
-
20
-
-
61349122608
-
MicroRNA miR-7 is preferentially expressed in endocrine cells of the developing and adult human pancreas
-
PMID: 19135553
-
Correa-Medina M, Bravo-Egana V, Rosero S, Ricordi C, Edlund H, Diez J, et al. (2009) MicroRNA miR-7 is preferentially expressed in endocrine cells of the developing and adult human pancreas. Gene Expr Patterns 9: 193-199. doi: 10.1016/j.gep.2008.12.003 PMID: 19135553
-
(2009)
Gene Expr Patterns
, vol.9
, pp. 193-199
-
-
Correa-Medina, M.1
Bravo-Egana, V.2
Rosero, S.3
Ricordi, C.4
Edlund, H.5
Diez, J.6
-
21
-
-
84900797916
-
MicroRNA-7a regulates pancreatic beta cell function
-
PMID: 24789908
-
Latreille M, Hausser J, Stutzer I, Zhang Q, Hastoy B, Gargani S, et al. (2014) MicroRNA-7a regulates pancreatic beta cell function. J Clin Invest 124: 2722-2735. doi: 10.1172/JCI73066 PMID: 24789908
-
(2014)
J Clin Invest
, vol.124
, pp. 2722-2735
-
-
Latreille, M.1
Hausser, J.2
Stutzer, I.3
Zhang, Q.4
Hastoy, B.5
Gargani, S.6
-
22
-
-
37549021902
-
Quantitative differential expression analysis reveals miR-7 as major islet microRNA
-
PMID: 18086561
-
Bravo-Egana V, Rosero S, Molano RD, Pileggi A, Ricordi C, Dominguez-Bendala J, et al. (2008) Quantitative differential expression analysis reveals miR-7 as major islet microRNA. Biochem Biophys Res Commun 366: 922-926. PMID: 18086561
-
(2008)
Biochem Biophys Res Commun
, vol.366
, pp. 922-926
-
-
Bravo-Egana, V.1
Rosero, S.2
Molano, R.D.3
Pileggi, A.4
Ricordi, C.5
Dominguez-Bendala, J.6
-
23
-
-
58149350343
-
miR-375 targets 3′-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells
-
PMID: 18591395
-
El Ouaamari A, Baroukh N, Martens GA, Lebrun P, Pipeleers D, van Obberghen E (2008) miR-375 targets 3′-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells. Diabetes 57: 2708-2717. doi: 10.2337/db07-1614 PMID: 18591395
-
(2008)
Diabetes
, vol.57
, pp. 2708-2717
-
-
El Ouaamari, A.1
Baroukh, N.2
Martens, G.A.3
Lebrun, P.4
Pipeleers, D.5
Van Obberghen, E.6
-
24
-
-
0029804116
-
Mechanism of activation of protein kinase B by insulin and IGF-1
-
PMID: 8978681
-
Alessi DR, Andjelkovic M, Caudwell B, Cron P, Morrice N, Cohen P, et al. (1996) Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J 15: 6541-6551. PMID: 8978681
-
(1996)
EMBO J
, vol.15
, pp. 6541-6551
-
-
Alessi, D.R.1
Andjelkovic, M.2
Caudwell, B.3
Cron, P.4
Morrice, N.5
Cohen, P.6
-
25
-
-
77449116389
-
Glucose regulates steady-state levels of PDX1 via the reciprocal actions of GSK3 and AKT kinases
-
PMID: 19833727
-
Humphrey RK, Yu SM, Flores LE, Jhala US (2010) Glucose regulates steady-state levels of PDX1 via the reciprocal actions of GSK3 and AKT kinases. J Biol Chem 285: 3406-3416. doi: 10.1074/jbc.M109.006734 PMID: 19833727
-
(2010)
J Biol Chem
, vol.285
, pp. 3406-3416
-
-
Humphrey, R.K.1
Yu, S.M.2
Flores, L.E.3
Jhala, U.S.4
-
26
-
-
33646549635
-
Phosphorylation marks IPF1/PDX1 protein for degradation by glycogen synthase kinase 3-dependent mechanisms
-
PMID: 16407209
-
Boucher MJ, Selander L, Carlsson L, Edlund H (2006) Phosphorylation marks IPF1/PDX1 protein for degradation by glycogen synthase kinase 3-dependent mechanisms. J Biol Chem 281: 6395-6403. PMID: 16407209
-
(2006)
J Biol Chem
, vol.281
, pp. 6395-6403
-
-
Boucher, M.J.1
Selander, L.2
Carlsson, L.3
Edlund, H.4
-
27
-
-
34748860815
-
MafA stability in pancreatic beta cells is regulated by glucose and is dependent on its constitutive phosphorylation at multiple sites by glycogen synthase kinase 3
-
PMID: 17682063
-
Han SI, Aramata S, Yasuda K, Kataoka K (2007) MafA stability in pancreatic beta cells is regulated by glucose and is dependent on its constitutive phosphorylation at multiple sites by glycogen synthase kinase 3. Mol Cell Biol 27: 6593-6605. PMID: 17682063
-
(2007)
Mol Cell Biol
, vol.27
, pp. 6593-6605
-
-
Han, S.I.1
Aramata, S.2
Yasuda, K.3
Kataoka, K.4
-
28
-
-
0035087123
-
Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death
-
PMID: 11279265
-
Cross DA, Culbert AA, Chalmers KA, Facci L, Skaper SD, Reith AD (2001) Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death. J Neurochem 77: 94-102. PMID: 11279265
-
(2001)
J Neurochem
, vol.77
, pp. 94-102
-
-
Cross, D.A.1
Culbert, A.A.2
Chalmers, K.A.3
Facci, L.4
Skaper, S.D.5
Reith, A.D.6
-
29
-
-
84862171364
-
The many faces and functions of beta-catenin
-
PMID: 22617422
-
Valenta T, Hausmann G, Basler K (2012) The many faces and functions of beta-catenin. EMBO J 31: 2714-2736. doi: 10.1038/emboj.2012.150 PMID: 22617422
-
(2012)
EMBO J
, vol.31
, pp. 2714-2736
-
-
Valenta, T.1
Hausmann, G.2
Basler, K.3
-
30
-
-
33646351055
-
Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass
-
PMID: 16642023
-
Hashimoto N, Kido Y, Uchida T, Asahara S, Shigeyama Y, Matsuda T, et al. (2006) Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass. Nat Genet 38: 589-593. PMID: 16642023
-
(2006)
Nat Genet
, vol.38
, pp. 589-593
-
-
Hashimoto, N.1
Kido, Y.2
Uchida, T.3
Asahara, S.4
Shigeyama, Y.5
Matsuda, T.6
-
31
-
-
60449085471
-
Regulation of pancreas plasticity and malignant transformation by Akt signaling
-
PMID: 19121634
-
Elghazi L, Weiss AJ, Barker DJ, Callaghan J, Staloch L, Sandgren EP, et al. (2009) Regulation of pancreas plasticity and malignant transformation by Akt signaling. Gastroenterology 136: 1091-1103. doi: 10.1053/j.gastro.2008.11.043 PMID: 19121634
-
(2009)
Gastroenterology
, vol.136
, pp. 1091-1103
-
-
Elghazi, L.1
Weiss, A.J.2
Barker, D.J.3
Callaghan, J.4
Staloch, L.5
Sandgren, E.P.6
-
32
-
-
0034941567
-
Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells
-
PMID: 11463845
-
Rossig L, Jadidi AS, Urbich C, Badorff C, Zeiher AM, Dimmeler S (2001) Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells. Mol Cell Biol 21: 5644-5657. PMID: 11463845
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5644-5657
-
-
Rossig, L.1
Jadidi, A.S.2
Urbich, C.3
Badorff, C.4
Zeiher, A.M.5
Dimmeler, S.6
-
33
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
PMID: 8524413
-
Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA (1995) Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378: 785-789. PMID: 8524413
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, P.3
Andjelkovich, M.4
Hemmings, B.A.5
-
34
-
-
0036090823
-
Glycogen synthase kinase 3: An emerging therapeutic target
-
PMID: 11879773
-
Eldar-Finkelman H (2002) Glycogen synthase kinase 3: an emerging therapeutic target. Trends Mol Med 8: 126-132. PMID: 11879773
-
(2002)
Trends Mol Med
, vol.8
, pp. 126-132
-
-
Eldar-Finkelman, H.1
-
35
-
-
78649335126
-
Conditional ablation of Gsk-3beta in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice
-
PMID: 20821187
-
Liu Y, Tanabe K, Baronnier D, Patel S, Woodgett J, Cras-Meneur C, et al. (2010) Conditional ablation of Gsk-3beta in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice. Diabetologia 53: 2600-2610. doi: 10.1007/s00125-010-1882-x PMID: 20821187
-
(2010)
Diabetologia
, vol.53
, pp. 2600-2610
-
-
Liu, Y.1
Tanabe, K.2
Baronnier, D.3
Patel, S.4
Woodgett, J.5
Cras-Meneur, C.6
-
36
-
-
33646795341
-
Targeting GSK-3: A promising approach for cancer therapy?
-
PMID: 16556076
-
Ougolkov AV, Billadeau DD (2006) Targeting GSK-3: a promising approach for cancer therapy? Future Oncol 2: 91-100. PMID: 16556076
-
(2006)
Future Oncol
, vol.2
, pp. 91-100
-
-
Ougolkov, A.V.1
Billadeau, D.D.2
-
37
-
-
54549120290
-
Glycogen synthase kinase-3 and cancer: Good cop, bad cop?
-
PMID: 18977324
-
Patel S, Woodgett J (2008) Glycogen synthase kinase-3 and cancer: good cop, bad cop? Cancer Cell 14: 351-353. doi: 10.1016/j.ccr.2008.10.013 PMID: 18977324
-
(2008)
Cancer Cell
, vol.14
, pp. 351-353
-
-
Patel, S.1
Woodgett, J.2
-
38
-
-
84903964215
-
SHOX2 is a direct miR-375 target and a novel epithelial-to-mesenchymal transition inducer in breast cancer cells
-
PMID: 24746361
-
Hong S, Noh H, Teng Y, Shao J, Rehmani H, Ding HF, et al. (2014) SHOX2 is a direct miR-375 target and a novel epithelial-to-mesenchymal transition inducer in breast cancer cells. Neoplasia 16: 279-290 e271-275. doi: 10.1016/j.neo.2014.03.010 PMID: 24746361
-
(2014)
Neoplasia
, vol.16
-
-
Hong, S.1
Noh, H.2
Teng, Y.3
Shao, J.4
Rehmani, H.5
Ding, H.F.6
|