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Volumn 539, Issue 2, 2014, Pages 213-223

MicroRNA expression profiling and functional annotation analysis of their targets in patients with type 1 diabetes mellitus

Author keywords

Expression profile; Functional annotation analysis; Microarray; MicroRNA; T1DM candidate genes; Type 1 diabetes mellitus

Indexed keywords

MICRORNA; SMALL UNTRANSLATED RNA;

EID: 84896715542     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2014.01.075     Document Type: Article
Times cited : (53)

References (75)
  • 1
    • 84871941957 scopus 로고    scopus 로고
    • Diagnosis and classification of diabetes mellitus
    • ADA (American Diabetes Association)
    • ADA (American Diabetes Association) Diagnosis and classification of diabetes mellitus. Diabetes Care 2013, 36(Suppl. 1):S67-S74.
    • (2013) Diabetes Care , vol.36 , Issue.SUPPL. 1
  • 2
    • 55149086806 scopus 로고    scopus 로고
    • Serum Th1 (CXCL10) and Th2 (CCL2) chemokine levels in children with newly diagnosed Type 1 diabetes: a longitudinal study
    • Antonelli A., et al. Serum Th1 (CXCL10) and Th2 (CCL2) chemokine levels in children with newly diagnosed Type 1 diabetes: a longitudinal study. Diabet. Med. 2008, 25:1349-1353.
    • (2008) Diabet. Med. , vol.25 , pp. 1349-1353
    • Antonelli, A.1
  • 3
    • 84872860732 scopus 로고    scopus 로고
    • Urinary microRNA profiling in the nephropathy of type 1 diabetes
    • Argyropoulos C., et al. Urinary microRNA profiling in the nephropathy of type 1 diabetes. PLoS One 2013, 8:e54662.
    • (2013) PLoS One , vol.8
    • Argyropoulos, C.1
  • 4
    • 79953726990 scopus 로고    scopus 로고
    • Impaired miR-146a expression links subclinical inflammation and insulin resistance in Type 2 diabetes
    • Balasubramanyam M., et al. Impaired miR-146a expression links subclinical inflammation and insulin resistance in Type 2 diabetes. Mol. Cell. Biochem. 2011, 351:197-205.
    • (2011) Mol. Cell. Biochem. , vol.351 , pp. 197-205
    • Balasubramanyam, M.1
  • 5
    • 67349199566 scopus 로고    scopus 로고
    • Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
    • Barrett J.C., et al. Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nat. Genet. 2009, 41:703-707.
    • (2009) Nat. Genet. , vol.41 , pp. 703-707
    • Barrett, J.C.1
  • 6
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 7
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • Bartel D.P. MicroRNAs: target recognition and regulatory functions. Cell 2009, 136:215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 8
    • 0021343570 scopus 로고
    • A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus
    • Bell G.I., Horita S., Karam J.H. A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus. Diabetes 1984, 33:176-183.
    • (1984) Diabetes , vol.33 , pp. 176-183
    • Bell, G.I.1    Horita, S.2    Karam, J.H.3
  • 9
    • 26444607248 scopus 로고    scopus 로고
    • Centre for Mathematical Sciences, Lund University, (Preprint 2004:18. Access March 10, 2013)
    • Bengtsson H. Aroma - an R object-oriented microarray analysis environment 2004, Centre for Mathematical Sciences, Lund University, (Preprint 2004:18, http://www.bioconductor.org/packages/release/bioc/html/aroma.light.html. Access March 10, 2013).
    • (2004) Aroma - an R object-oriented microarray analysis environment
    • Bengtsson, H.1
  • 10
    • 72149133679 scopus 로고    scopus 로고
    • MicroRNAs miR-1, miR-133a, miR-133b and miR-208 are dysregulated in human myocardial infarction
    • Bostjancic E., Zidar N., Stajer D., Glavac D. MicroRNAs miR-1, miR-133a, miR-133b and miR-208 are dysregulated in human myocardial infarction. Cardiology 2010, 115:163-169.
    • (2010) Cardiology , vol.115 , pp. 163-169
    • Bostjancic, E.1    Zidar, N.2    Stajer, D.3    Glavac, D.4
  • 11
    • 12144291502 scopus 로고    scopus 로고
    • A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
    • Bottini N., et al. A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat. Genet. 2004, 36:337-338.
    • (2004) Nat. Genet. , vol.36 , pp. 337-338
    • Bottini, N.1
  • 12
    • 78651275599 scopus 로고    scopus 로고
    • T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research
    • Burren O.S., Adlem E.C., Achuthan P., Christensen M., Coulson R.M., Todd J.A. T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research. Nucleic Acids Res. 2011, 39:D997-D1001.
    • (2011) Nucleic Acids Res. , vol.39
    • Burren, O.S.1    Adlem, E.C.2    Achuthan, P.3    Christensen, M.4    Coulson, R.M.5    Todd, J.A.6
  • 13
    • 84888156471 scopus 로고    scopus 로고
    • Identifying common and specific microRNAs expressed in peripheral blood mononuclear cell of type 1, type 2, and gestational diabetes mellitus patients
    • Collares C.V., et al. Identifying common and specific microRNAs expressed in peripheral blood mononuclear cell of type 1, type 2, and gestational diabetes mellitus patients. BMC Res. Notes 2013, 6:491.
    • (2013) BMC Res. Notes , vol.6 , pp. 491
    • Collares, C.V.1
  • 14
    • 84878065323 scopus 로고    scopus 로고
    • Decreased expression of miR-133a but not of miR-1 is associated with signs of heart failure in patients undergoing coronary bypass surgery
    • Danowski N., Manthey I., Jakob H.G., Siffert W., Peters J., Frey U.H. Decreased expression of miR-133a but not of miR-1 is associated with signs of heart failure in patients undergoing coronary bypass surgery. Cardiology 2013, 125:125-130.
    • (2013) Cardiology , vol.125 , pp. 125-130
    • Danowski, N.1    Manthey, I.2    Jakob, H.G.3    Siffert, W.4    Peters, J.5    Frey, U.H.6
  • 15
    • 84884481056 scopus 로고    scopus 로고
    • Tumor suppressor functions of miR-133a in colorectal cancer
    • Dong Y., et al. Tumor suppressor functions of miR-133a in colorectal cancer. Mol. Cancer Res. 2013, 11:1051-1060.
    • (2013) Mol. Cancer Res. , vol.11 , pp. 1051-1060
    • Dong, Y.1
  • 16
    • 79959805164 scopus 로고    scopus 로고
    • MiRWalk-database: prediction of possible miRNA binding sites by "walking" the genes of three genomes
    • Dweep H., Sticht C., Pandey P., Gretz N. miRWalk-database: prediction of possible miRNA binding sites by "walking" the genes of three genomes. J. Biomed. Inform. 2011, 44:839-847.
    • (2011) J. Biomed. Inform. , vol.44 , pp. 839-847
    • Dweep, H.1    Sticht, C.2    Pandey, P.3    Gretz, N.4
  • 17
    • 84859254586 scopus 로고    scopus 로고
    • The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines
    • Eizirik D.L., et al. The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines. PLoS Genet. 2012, 8:e1002552.
    • (2012) PLoS Genet. , vol.8
    • Eizirik, D.L.1
  • 18
    • 84896701454 scopus 로고    scopus 로고
    • Enhanced Heat Map (heatmap.2), (Access April 10, 2013)
    • Enhanced Heat Map (heatmap.2) (Access April 10, 2013). http://hosho.ees.hokudai.ac.jp/~kubo/Rdoc/library/gplots/html/heatmap.2.html.
  • 19
    • 84890120401 scopus 로고    scopus 로고
    • SDF-1-CXCR4 differentially regulates autoimmune diabetogenic T cell adhesion through ROBO1-SLIT2 interactions in mice
    • Glawe J.D., et al. SDF-1-CXCR4 differentially regulates autoimmune diabetogenic T cell adhesion through ROBO1-SLIT2 interactions in mice. Diabetologia 2013, 56:2222-2230.
    • (2013) Diabetologia , vol.56 , pp. 2222-2230
    • Glawe, J.D.1
  • 20
    • 77951522456 scopus 로고    scopus 로고
    • Oxidative damage to DNA and lipids: correlation with protein glycation in patients with type 1 diabetes
    • Goodarzi M.T., Navidi A.A., Rezaei M., Babahmadi-Rezaei H. Oxidative damage to DNA and lipids: correlation with protein glycation in patients with type 1 diabetes. J. Clin. Lab. Anal. 2010, 24:72-76.
    • (2010) J. Clin. Lab. Anal. , vol.24 , pp. 72-76
    • Goodarzi, M.T.1    Navidi, A.A.2    Rezaei, M.3    Babahmadi-Rezaei, H.4
  • 21
    • 77954664186 scopus 로고    scopus 로고
    • A viral microRNA down-regulates multiple cell cycle genes through mRNA 5'UTRs
    • Grey F., et al. A viral microRNA down-regulates multiple cell cycle genes through mRNA 5'UTRs. PLoS Pathog. 2010, 6:e1000967.
    • (2010) PLoS Pathog. , vol.6
    • Grey, F.1
  • 25
    • 77950920903 scopus 로고    scopus 로고
    • Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP
    • Hafner M., et al. Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell 2010, 141:129-141.
    • (2010) Cell , vol.141 , pp. 129-141
    • Hafner, M.1
  • 26
    • 33645090947 scopus 로고    scopus 로고
    • Altered chemokine levels in individuals at risk of Type 1 diabetes mellitus
    • Hanifi-Moghaddam P., et al. Altered chemokine levels in individuals at risk of Type 1 diabetes mellitus. Diabet. Med. 2006, 23:156-163.
    • (2006) Diabet. Med. , vol.23 , pp. 156-163
    • Hanifi-Moghaddam, P.1
  • 28
    • 84876935138 scopus 로고    scopus 로고
    • Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding
    • Helwak A., Kudla G., Dudnakova T., Tollervey D. Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding. Cell 2013, 153:654-665.
    • (2013) Cell , vol.153 , pp. 654-665
    • Helwak, A.1    Kudla, G.2    Dudnakova, T.3    Tollervey, D.4
  • 29
    • 71349083569 scopus 로고    scopus 로고
    • MicroRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients
    • Hezova R., et al. microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients. Cell. Immunol. 2010, 260:70-74.
    • (2010) Cell. Immunol. , vol.260 , pp. 70-74
    • Hezova, R.1
  • 30
    • 84896698282 scopus 로고    scopus 로고
    • Hierarchical Clustering (hclust), (Access April 10, 2013)
    • Hierarchical Clustering (hclust) (Access April 10, 2013). http://stat.ethz.ch/R-manual/R-devel/library/stats/html/hclust.html.
  • 31
    • 33751006151 scopus 로고    scopus 로고
    • RankProd: a bioconductor package for detecting differentially expressed genes in meta-analysis
    • Hong F., Breitling R., McEntee C.W., Wittner B.S., Nemhauser J.L., Chory J. RankProd: a bioconductor package for detecting differentially expressed genes in meta-analysis. Bioinformatics 2006, 22:2825-2827.
    • (2006) Bioinformatics , vol.22 , pp. 2825-2827
    • Hong, F.1    Breitling, R.2    McEntee, C.W.3    Wittner, B.S.4    Nemhauser, J.L.5    Chory, J.6
  • 32
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists
    • Huang D.W., Sherman B.T., Lempicki R.A. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res. 2009, 37:1-13.
    • (2009) Nucleic Acids Res. , vol.37 , pp. 1-13
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 33
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang D.W., Sherman B.T., Lempicki R.A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 2009, 4:44-57.
    • (2009) Nat. Protoc. , vol.4 , pp. 44-57
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 34
    • 2342531842 scopus 로고    scopus 로고
    • IDF (International Diabetes Federation), (Access June 25, 2013)
    • IDF (International Diabetes Federation) The global burden, IDF diabetes Atlas 5th edition (Access June 25, 2013). http://www.idf.org/diabetesatlas/5e/the-global-burden.
    • The global burden, IDF diabetes Atlas 5th edition
  • 35
    • 84855996930 scopus 로고    scopus 로고
    • MicroRNA molecular profiles associated with diagnosis, clinicopathologic criteria, and overall survival in patients with resectable pancreatic ductal adenocarcinoma
    • Jamieson N.B., et al. MicroRNA molecular profiles associated with diagnosis, clinicopathologic criteria, and overall survival in patients with resectable pancreatic ductal adenocarcinoma. Clin. Cancer Res. 2012, 18:534-545.
    • (2012) Clin. Cancer Res. , vol.18 , pp. 534-545
    • Jamieson, N.B.1
  • 36
    • 79960932477 scopus 로고    scopus 로고
    • MicroRNA 144 impairs insulin signaling by inhibiting the expression of insulin receptor substrate 1 in type 2 diabetes mellitus
    • Karolina D.S., et al. MicroRNA 144 impairs insulin signaling by inhibiting the expression of insulin receptor substrate 1 in type 2 diabetes mellitus. PLoS One 2011, 6:e22839.
    • (2011) PLoS One , vol.6
    • Karolina, D.S.1
  • 37
    • 78651293534 scopus 로고    scopus 로고
    • MiRBase: integrating microRNA annotation and deep-sequencing data
    • Kozomara A., Griffiths-Jones S. miRBase: integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res. 2011, 39:D152-D157.
    • (2011) Nucleic Acids Res. , vol.39
    • Kozomara, A.1    Griffiths-Jones, S.2
  • 38
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis, function and decay
    • Krol J., Loedige I., Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 2010, 11:597-610.
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 597-610
    • Krol, J.1    Loedige, I.2    Filipowicz, W.3
  • 39
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee R.C., Feinbaum R.L., Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993, 75:843-854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 40
    • 80055013733 scopus 로고    scopus 로고
    • Suppression of the PI3K-Akt pathway is involved in the decreased adhesion and migration of bone marrow-derived mesenchymal stem cells from non-obese diabetic mice
    • Li L., et al. Suppression of the PI3K-Akt pathway is involved in the decreased adhesion and migration of bone marrow-derived mesenchymal stem cells from non-obese diabetic mice. Cell Biol. Int. 2011, 35:961-966.
    • (2011) Cell Biol. Int. , vol.35 , pp. 961-966
    • Li, L.1
  • 41
    • 33344454373 scopus 로고    scopus 로고
    • The peripheral blood transcriptome dynamically reflects system wide biology: a potential diagnostic tool
    • Liew C.C., Ma J., Tang H.C., Zheng R., Dempsey A.A. The peripheral blood transcriptome dynamically reflects system wide biology: a potential diagnostic tool. J. Lab. Clin. Med. 2006, 147:126-132.
    • (2006) J. Lab. Clin. Med. , vol.147 , pp. 126-132
    • Liew, C.C.1    Ma, J.2    Tang, H.C.3    Zheng, R.4    Dempsey, A.A.5
  • 42
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • Lim L.P., et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 2005, 433:769-773.
    • (2005) Nature , vol.433 , pp. 769-773
    • Lim, L.P.1
  • 43
    • 84880445150 scopus 로고    scopus 로고
    • Microarray analysis of microRNA expression in liver cancer tissues and normal control
    • Lin L., Lin Y., Jin Y., Zheng C. Microarray analysis of microRNA expression in liver cancer tissues and normal control. Gene 2013, 523:158-160.
    • (2013) Gene , vol.523 , pp. 158-160
    • Lin, L.1    Lin, Y.2    Jin, Y.3    Zheng, C.4
  • 44
    • 84861970489 scopus 로고    scopus 로고
    • Differential microRNA expression in peripheral blood mononuclear cells from Graves' disease patients
    • Liu R., et al. Differential microRNA expression in peripheral blood mononuclear cells from Graves' disease patients. J. Clin. Endocrinol. Metab. 2012, 97:E968-E972.
    • (2012) J. Clin. Endocrinol. Metab. , vol.97
    • Liu, R.1
  • 45
    • 34548367511 scopus 로고    scopus 로고
    • Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes
    • Lowe C.E., et al. Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes. Nat. Genet. 2007, 39:1074-1082.
    • (2007) Nat. Genet. , vol.39 , pp. 1074-1082
    • Lowe, C.E.1
  • 47
    • 84884820730 scopus 로고    scopus 로고
    • MicroRNAs as pharmacological targets in diabetes
    • Mao Y., Mohan R., Zhang S., Tang X. MicroRNAs as pharmacological targets in diabetes. Pharmacol. Res. 2013, 75:37-47.
    • (2013) Pharmacol. Res. , vol.75 , pp. 37-47
    • Mao, Y.1    Mohan, R.2    Zhang, S.3    Tang, X.4
  • 48
    • 84870360348 scopus 로고    scopus 로고
    • Differentially expressed miRNAs in retinoblastoma
    • Martin J., et al. Differentially expressed miRNAs in retinoblastoma. Gene 2013, 512:294-299.
    • (2013) Gene , vol.512 , pp. 294-299
    • Martin, J.1
  • 49
    • 79960135400 scopus 로고    scopus 로고
    • MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function
    • Minones-Moyano E., et al. MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function. Hum. Mol. Genet. 2011, 20:3067-3078.
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 3067-3078
    • Minones-Moyano, E.1
  • 50
    • 84864981566 scopus 로고    scopus 로고
    • Circulating levels of microRNA from children with newly diagnosed type 1 diabetes and healthy controls: evidence that miR-25 associates to residual beta-cell function and glycaemic control during disease progression
    • Nielsen L.B., et al. Circulating levels of microRNA from children with newly diagnosed type 1 diabetes and healthy controls: evidence that miR-25 associates to residual beta-cell function and glycaemic control during disease progression. Exp. Diabetes Res. 2012, 2012:896362.
    • (2012) Exp. Diabetes Res. , vol.2012 , pp. 896362
    • Nielsen, L.B.1
  • 51
    • 8944259914 scopus 로고    scopus 로고
    • The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry
    • Nistico L., et al. The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry. Hum. Mol. Genet. 1996, 5:1075-1080.
    • (1996) Hum. Mol. Genet. , vol.5 , pp. 1075-1080
    • Nistico, L.1
  • 52
    • 54949113578 scopus 로고    scopus 로고
    • Functional organization of the transcriptome in human brain
    • Oldham M.C., et al. Functional organization of the transcriptome in human brain. Nat. Neurosci. 2008, 11:1271-1282.
    • (2008) Nat. Neurosci. , vol.11 , pp. 1271-1282
    • Oldham, M.C.1
  • 54
    • 52249094653 scopus 로고    scopus 로고
    • Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients
    • Pauley K.M., Satoh M., Chan A.L., Bubb M.R., Reeves W.H., Chan E.K. Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Res. Ther. 2008, 10:R101.
    • (2008) Arthritis Res. Ther. , vol.10
    • Pauley, K.M.1    Satoh, M.2    Chan, A.L.3    Bubb, M.R.4    Reeves, W.H.5    Chan, E.K.6
  • 55
    • 84874372441 scopus 로고    scopus 로고
    • Analysis of altered microRNA expression profiles in peripheral blood mononuclear cells from patients with primary biliary cirrhosis
    • Qin B., Huang F., Liang Y., Yang Z., Zhong R. Analysis of altered microRNA expression profiles in peripheral blood mononuclear cells from patients with primary biliary cirrhosis. J. Gastroenterol. Hepatol. 2013, 28:543-550.
    • (2013) J. Gastroenterol. Hepatol. , vol.28 , pp. 543-550
    • Qin, B.1    Huang, F.2    Liang, Y.3    Yang, Z.4    Zhong, R.5
  • 56
    • 84863304598 scopus 로고    scopus 로고
    • R Development Core Team, R Foundation for Statistical Computing, (Access April 10, 2013)
    • R Development Core Team R: a language and environment for statistical computing 2006, R Foundation for Statistical Computing, (http://www.r-project.org. Access April 10, 2013).
    • (2006) R: a language and environment for statistical computing
  • 58
    • 84875061922 scopus 로고    scopus 로고
    • Expression and genetic analysis of MicroRNAs involved in multiple sclerosis
    • Ridolfi E., et al. Expression and genetic analysis of MicroRNAs involved in multiple sclerosis. Int. J. Mol. Sci. 2013, 14:4375-4384.
    • (2013) Int. J. Mol. Sci. , vol.14 , pp. 4375-4384
    • Ridolfi, E.1
  • 59
    • 84875669193 scopus 로고    scopus 로고
    • MicroRNAs miR-21a and miR-93 are down regulated in peripheral blood mononuclear cells (PBMCs) from patients with type 1 diabetes
    • Salas-Perez F., Codner E., Valencia E., Pizarro C., Carrasco E., Perez-Bravo F. MicroRNAs miR-21a and miR-93 are down regulated in peripheral blood mononuclear cells (PBMCs) from patients with type 1 diabetes. Immunobiology 2013, 218:733-737.
    • (2013) Immunobiology , vol.218 , pp. 733-737
    • Salas-Perez, F.1    Codner, E.2    Valencia, E.3    Pizarro, C.4    Carrasco, E.5    Perez-Bravo, F.6
  • 61
    • 38449086913 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1/CXCL12 stimulates chemorepulsion of NOD/LtJ T-cell adhesion to islet microvascular endothelium
    • Sharp C.D., et al. Stromal cell-derived factor-1/CXCL12 stimulates chemorepulsion of NOD/LtJ T-cell adhesion to islet microvascular endothelium. Diabetes 2008, 57:102-112.
    • (2008) Diabetes , vol.57 , pp. 102-112
    • Sharp, C.D.1
  • 62
    • 77954249988 scopus 로고    scopus 로고
    • Cancer risk among patients hospitalized for Type 1 diabetes mellitus: a population-based cohort study in Sweden
    • Shu X., Ji J., Li X., Sundquist J., Sundquist K., Hemminki K. Cancer risk among patients hospitalized for Type 1 diabetes mellitus: a population-based cohort study in Sweden. Diabet. Med. 2010, 27:791-797.
    • (2010) Diabet. Med. , vol.27 , pp. 791-797
    • Shu, X.1    Ji, J.2    Li, X.3    Sundquist, J.4    Sundquist, K.5    Hemminki, K.6
  • 63
    • 27544491192 scopus 로고    scopus 로고
    • ROCR: visualizing classifier performance in R
    • Sing T., Sander O., Beerenwinkel N., Lengauer T. ROCR: visualizing classifier performance in R. Bioinformatics 2005, 21:3940-3941. (http://rocr.bioinf.mpi-sb.mpg.de/).
    • (2005) Bioinformatics , vol.21 , pp. 3940-3941
    • Sing, T.1    Sander, O.2    Beerenwinkel, N.3    Lengauer, T.4
  • 64
    • 4143090557 scopus 로고    scopus 로고
    • Cytokines activate genes of the endocytotic pathway in insulin-producing RINm5F cells
    • Souza K.L., Elsner M., Mathias P.C., Lenzen S., Tiedge M. Cytokines activate genes of the endocytotic pathway in insulin-producing RINm5F cells. Diabetologia 2004, 47:1292-1302.
    • (2004) Diabetologia , vol.47 , pp. 1292-1302
    • Souza, K.L.1    Elsner, M.2    Mathias, P.C.3    Lenzen, S.4    Tiedge, M.5
  • 65
    • 84878653583 scopus 로고    scopus 로고
    • Blood microRNAs in Low or No Risk Ischemic Stroke Patients
    • Tan J.R., et al. Blood microRNAs in Low or No Risk Ischemic Stroke Patients. Int. J. Mol. Sci. 2013, 14:2072-2084.
    • (2013) Int. J. Mol. Sci. , vol.14 , pp. 2072-2084
    • Tan, J.R.1
  • 66
    • 12444262883 scopus 로고    scopus 로고
    • Formation of advanced glycosylation end products and oxidative stress in young patients with type 1 diabetes
    • Tsukahara H., et al. Formation of advanced glycosylation end products and oxidative stress in young patients with type 1 diabetes. Pediatr. Res. 2003, 54:419-424.
    • (2003) Pediatr. Res. , vol.54 , pp. 419-424
    • Tsukahara, H.1
  • 67
    • 78751662679 scopus 로고    scopus 로고
    • Type 1 diabetes: etiology, immunology, and therapeutic strategies
    • van Belle T.L., Coppieters K.T., von Herrath M.G. Type 1 diabetes: etiology, immunology, and therapeutic strategies. Physiol. Rev. 2011, 91:79-118.
    • (2011) Physiol. Rev. , vol.91 , pp. 79-118
    • van Belle, T.L.1    Coppieters, K.T.2    von Herrath, M.G.3
  • 68
    • 77954270706 scopus 로고    scopus 로고
    • Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood
    • Vaz C., et al. Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood. BMC Genomics 2010, 11:288.
    • (2010) BMC Genomics , vol.11 , pp. 288
    • Vaz, C.1
  • 69
    • 84872500342 scopus 로고    scopus 로고
    • Iatrogenic hyperinsulinemia in type 1 diabetes: its effect on atherogenic risk markers
    • Wang M.Y., et al. Iatrogenic hyperinsulinemia in type 1 diabetes: its effect on atherogenic risk markers. J. Diabetes Complications 2013, 27:70-74.
    • (2013) J. Diabetes Complications , vol.27 , pp. 70-74
    • Wang, M.Y.1
  • 71
    • 0030774675 scopus 로고    scopus 로고
    • Cancer incidence in a population-based cohort of patients hospitalized with diabetes mellitus in Denmark
    • Wideroff L., et al. Cancer incidence in a population-based cohort of patients hospitalized with diabetes mellitus in Denmark. J. Natl. Cancer Inst. 1997, 89:1360-1365.
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 1360-1365
    • Wideroff, L.1
  • 72
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
    • Wightman B., Ha I., Ruvkun G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 1993, 75:855-862.
    • (1993) Cell , vol.75 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 73
    • 84880290282 scopus 로고    scopus 로고
    • De-repression of FOXO3a death axis by microRNA-132 and -212 causes neuronal apoptosis in Alzheimer's disease
    • Wong H.K., et al. De-repression of FOXO3a death axis by microRNA-132 and -212 causes neuronal apoptosis in Alzheimer's disease. Hum. Mol. Genet. 2013, 22:3077-3092.
    • (2013) Hum. Mol. Genet. , vol.22 , pp. 3077-3092
    • Wong, H.K.1
  • 74
    • 0346888536 scopus 로고    scopus 로고
    • Cancer incidence in patients with type 1 diabetes mellitus: a population-based cohort study in Sweden
    • Zendehdel K., Nyren O., Ostenson C.G., Adami H.O., Ekbom A., Ye W. Cancer incidence in patients with type 1 diabetes mellitus: a population-based cohort study in Sweden. J. Natl. Cancer Inst. 2003, 95:1797-1800.
    • (2003) J. Natl. Cancer Inst. , vol.95 , pp. 1797-1800
    • Zendehdel, K.1    Nyren, O.2    Ostenson, C.G.3    Adami, H.O.4    Ekbom, A.5    Ye, W.6
  • 75
    • 84875341825 scopus 로고    scopus 로고
    • Differential expression profiling and functional analysis of microRNAs through stages I-III papillary thyroid carcinoma
    • Zhang J., et al. Differential expression profiling and functional analysis of microRNAs through stages I-III papillary thyroid carcinoma. Int. J. Med. Sci. 2013, 10:585-592.
    • (2013) Int. J. Med. Sci. , vol.10 , pp. 585-592
    • Zhang, J.1


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