Multimodal imaging for DREADD-expressing neurons in living brain and their application to implantation of iPSC-derived neural progenitors

Journal of Neuroscience

Volumn 36, Issue 45, 2016, Pages 11544-11558

  Ji, Bin ^a,d   Kaneko, Hiroyuki ^a   Minamimoto, Takafumi ^a   Inoue, Haruhisa ^b,d   Takeuchi, Hiroki ^b   Kumata, Katsushi ^a   Zhang, Ming Rong ^a   Aoki, Ichio ^a   Seki, Chie ^a   Ono, Maiko ^a   Tokunaga, Masaki ^a   Tsukamoto, Satoshi ^a   Tanabe, Koji ^b   Shin, Ryong Moon ^a   Minamihisamatsu, Takeharu ^a   Kito, Seiji ^a   Richmond, Barry J ^c   Suhara, Tetsuya ^a,d   Higuchi, Makoto ^a,d  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Cell replacement therapy; Clozapine N oxide (CNO); Designer receptor exclusively activated by designer drugs (DREADD); Induced pluripotent stem cell (iPSC); Positron emission tomography (PET)

Indexed keywords

BETA ACTIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EMBRYO; EXPERIMENTAL LOCOMOTOR ACTIVITY TEST; FIBROBLAST; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INDUCED PLURIPOTENT STEM CELL; MICROSCOPY; MOUSE; MULTIMODAL IMAGING; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; PERFUSION WEIGHTED IMAGING; POLYMERASE CHAIN REACTION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; WESTERN BLOTTING; ANIMAL; BRAIN; CELL CULTURE; CYTOLOGY; DIAGNOSTIC IMAGING; METABOLISM; NERVE CELL; PROCEDURES; REPORTER GENE; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; STEM CELL TRANSPLANTATION; TRANSGENIC MOUSE; TRANSPLANTATION;

ANIMALS; BRAIN; CELLS, CULTURED; GENES, REPORTER; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE; MICE, TRANSGENIC; MULTIMODAL IMAGING; NEURAL STEM CELLS; NEURONS; POSITRON-EMISSION TOMOGRAPHY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STEM CELL TRANSPLANTATION;

EID: 84994715846     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1279-16.2016     Document Type: Article

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