Increased 12/15-Lipoxygenase Leads to Widespread Brain Injury Following Global Cerebral Ischemia

Translational Stroke Research

Volumn 8, Issue 2, 2017, Pages 194-202

  Yigitkanli, Kazim ^a,b   Zheng, Yi ^a   Pekcec, Anton ^a,c   Lo, Eng H ^a   van Leyen, Klaus ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Polatli Hospital   (Turkey)

^c BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Apoptosis; Cardiac arrest; Cortex; Global cerebral ischemia; Hippocampus; Lipoxygenase

Indexed keywords

APOPTOSIS INDUCING FACTOR; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; CASPASE 3; LIPOXYGENASE INHIBITOR; ALOX15 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD VESSEL; BRAIN CORTEX; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN NERVE CELL; CONTROLLED STUDY; CORPUS STRIATUM; DISEASE ASSOCIATION; ENZYME ACTIVATION; ENZYME LOCALIZATION; HIPPOCAMPUS; MALE; MOUSE; NERVE CELL NECROSIS; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; ANIMAL; APOPTOSIS; BRAIN; C57BL MOUSE; GENETICS; INJURIES; KNOCKOUT MOUSE; METABOLISM; NERVE CELL;

ANIMALS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE; BRAIN; BRAIN INJURIES; BRAIN ISCHEMIA; CEREBRAL CORTEX; CORPUS STRIATUM; HIPPOCAMPUS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS;

EID: 84994710021     PISSN: 18684483     EISSN: 1868601X     Source Type: Journal    
DOI: 10.1007/s12975-016-0509-z     Document Type: Article

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