Assessment at the single-cell level identifies neuronal glutathione depletion as both a cause and effect of ischemia-reperfusion oxidative stress

Journal of Neuroscience

Volumn 35, Issue 18, 2015, Pages 7143-7152

  Won, Seok Joon ^a,b   Kim, Ji Eun ^a,b,c   Cittolin Santos, Giordano Fabricio ^a,b   Swanson, Raymond A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c Hallym University College of Medicine   (South Korea)

Author keywords

Glutathione; Hyperglycemia; Ischemia; N acetyl cysteine; Neuron; Oxidative stress

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; GLUTATHIONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEPLETION; ENZYME ACTIVITY; ENZYME ASSAY; GLUTATHIONE DEPLETION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; METABOLISM; MOUSE; NEUROPIL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; REPERFUSION INJURY; ANIMAL; BRAIN ISCHEMIA; C57BL MOUSE; NERVE CELL; PATHOLOGY; PHYSIOLOGY;

ANIMALS; BRAIN ISCHEMIA; GLUTATHIONE; MALE; MICE; MICE, INBRED C57BL; NEURONS; OXIDATIVE STRESS; REPERFUSION INJURY;

EID: 84929340846     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4826-14.2015     Document Type: Article

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