Guidelines for Using Mouse Global Cerebral Ischemia Models

Translational Stroke Research

Volumn 4, Issue 3, 2013, Pages 343-350

  Kristian, Tibor ^a,b   Hu, Bingren ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b Vet Aff MD Health Care System   (United States)

Author keywords

Cell death; Global cerebral ischemia; Model; Mouse; Transgenic mouse

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; CAROTID ARTERY OBSTRUCTION; CONTROLLED STUDY; FEASIBILITY STUDY; HEART ARREST; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; PRACTICE GUIDELINE; PRIORITY JOURNAL;

ANIMALS; BLOOD PRESSURE; BRAIN; BRAIN DAMAGE, CHRONIC; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; HEART ARREST; HYPOTENSION; ISOFLURANE; LIGATION; MICE; MICE, TRANSGENIC;

EID: 84877144277     PISSN: 18684483     EISSN: 1868601X     Source Type: Journal    
DOI: 10.1007/s12975-012-0236-z     Document Type: Article

References (40)

1. Baughman VL, Hoffman WE, Miletich DJ, Albrecht RF, Thomas C. Neurologic outcome in rats following incomplete cerebral ischemia during halothane, isoflurane, or N2O. Anesthesiology. 1988; 69(2): 192-8.
2. Beckmann N. High resolution magnetic resonance angiography non-invasively reveals mouse strain differences in the cerebrovascular anatomy in vivo. Magn Reson Med. 2000; 44(2): 252-8.
3. Blanck TJ, Haile M, Xu F, Zhang J, Heerdt P, Veselis RA, Beckman J, Kang R, Adamo A, Hemmings H. Isoflurane pretreatment ameliorates postischemic neurologic dysfunction and preserves hippocampal Ca2+/calmodulin-dependent protein kinase in a canine cardiac arrest model. Anesthesiology. 2000; 93(5): 1285-93.
4. Bottiger BW, Schmitz B, Wiessner C, Vogel P, Hossmann KA. Neuronal stress response and neuronal cell damage after cardiocirculatory arrest in rats. J Cereb Blood Flow Metab. 1998; 18: 1077-87.
5. Bottiger BW, Teschendorf P, Krumnikl JJ, Vogel P, Galmbacher R, Schmitz B, Motsch J, Martin E, Gass P. Global cerebral ischemia due to cardiocirculatory arrest in mice causes neuronal degeneration and early induction of transcription factor genes in the hippocampus. Brain Res Mol Brain Res. 1999; 65(2): 135-42.
6. Degterev A, Huang Z, Boyce M, Li Y, Jagtap P, Mizushima N, Cuny GD, Mitchison TJ, Moskowitz MA, Yuan J. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol. 2005; 1(2): 112-9.
7. Horn M, Schlote W. Delayed neuronal death and delayed neuronal recovery in the human brain following global ischemia. Acta Neuropathol. 1992; 85: 79-87.
8. Elsersy H, Sheng H, Lynch JR, Moldovan M, Pearlstein RD, Warner DS. Effects of isoflurane versus fentanyl-nitrous oxide anesthesia on long-term outcome from severe forebrain ischemia in the rat. Anesthesiology. 2004; 100: 1160-6.
9. Hu BR, Park M, Martone ME, Fischer WH, Ellisman MH, Zivin JA. Assembly of proteins to postsynaptic densities after transient cerebral ischemia. J Neurosci. 1998; 18: 625-33.
10. Hu BR, Martone ME, Jones YZ, Liu CL. Protein aggregation following transient cerebral ischemia. J Neurosci. 2000; 20: 3191-9.
11. Fujii M, Hara H, Meng W, Vonsattel JP, Huang Z, Moskowitz MA. Strain-related differences in susceptibility to transient forebrain ischemia in SV-129 and C57black/6 mice. Stroke. 1997; 28(9): 1805-10. discussion 1811.
12. Ginsberg MD, Busto R. Rodent models of cerebral ischemia. Stroke. 1989; 20(12): 1627-42.
13. Hua F, Ma J, Li Y, Ha T, Xia Y, Kelley J, Williams DL, Browder IW, Schweitzer JB, Li C. The development of a novel mouse model of transient global cerebral ischemia. Neurosci Lett. 2006; 400(1-2): 69-74.
14. Kawaguchi M, Kimbro JR, Drummond JC, Cole DJ, Kelly PJ, Patel PM. Isoflurane delays but does not prevent cerebral infarction in rats subjected to focal ischemia. Anesthesiology. 2000; 92(5): 1335-42.
15. Kiessling M, Stumm G, Xie Y, Herdegen T, Aguzzi A, Bravo R, Gass P. Differential transcription and translation of immediate early genes in the gerbil hippocampus after transient global ischemia. J Cereb Blood Flow Metabol. 1993; 13: 914-24.
16. Kitagawa K, Matsumoto M, Yang G, Mabuchi T, Yagita Y, Hori M, Yanagihara T. Cerebral ischemia after bilateral carotid artery occlusion and intraluminal suture occlusion in mice: evaluation of the patency of the posterior communicating artery. J Cereb Blood Flow Metab. 1998; 18(5): 570-9.
17. Kofler J, Hattori K, Sawada M, DeVries AC, Martin LJ, Hurn PD, Traystman RJ. Histopathological and behavioral characterization of a novel model of cardiac arrest and cardiopulmonary resuscitation in mice. J Neurosci Methods. 2004; 136: 33-44.
18. Kristian T, Siesjo BK. Calcium in ischemic cell death. Stroke. 1998; 29(3): 705-18.
19. Liu CH, Gao Y, Barrett J, Hu BR. Protein aggregation and autophagy after brain ischemia. J Neurochem. 2010; 115: 68-78.
20. Mackensen GB, Nellgard B, Miura Y, Chu CT, Dexter F, Pearlstein RD, Warner DS. Sympathetic ganglionic blockade masks beneficial effect of isoflurane on histologic outcome from near-complete forebrain ischemia in the rat. Anesthesiology. 1999; 90(3): 873-81.
21. Miura Y, Grocott HP, Bart RD, Pearlstein RD, Dexter F, Warner DS. Differential effects of anesthetic agents on outcome from near-complete but not incomplete global ischemia in the rat. Anesthesiology. 1998; 89(2): 391-400.
22. Murakami K, Kondo T, Kawase M, Chan PH. The development of a new mouse model of global ischemia: focus on the relationships between ischemia duration, anesthesia, cerebral vasculature, and neuronal injury following global ischemia in mice. Brain Res. 1998; 780(2): 304-10.
23. Onken M, Berger S, Kristian T. Simple model of forebrain ischemia in mouse. J Neurosci Methods. 2012; 204: 254-61.
24. Panahian N, Yoshida T, Huang PL, Hedley-Whyte ET, Dalkara T, Fishman MC, Moskowitz MA. Attenuated hippocampal damage after global cerebral ischemia in mice mutant in neuronal nitric oxide synthase. Neuroscience. 1996; 72(2): 343-54.
25. Pegorini S, Braida D, Verzoni C, Guerini-Rocco C, Consalez GG, Croci L, Sala M. Capsaicin exhibits neuroprotective effects in a model of transient global cerebral ischemia in Mongolian gerbils. Br J Pharmacol. 2005; 144(5): 727-35.
26. Petito CK, Feldmann E, Pulsinelli WA, Plum F. Delayed hippocampal damage in humans following cardiorespiratory arrest. Neurology. 1987; 37: 1281-6.
27. Pulsinelli WA, Brierley JB. A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke. 1979; 10(3): 267-72.
28. Pulsinelli WA, Brierley JB, Plum F. Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann Neurol. 1982; 11: 491-8.
29. Saito A, Maier CM, Narasimhan P, Nishi T, Song YS, Yu F, Liu J, Lee YS, Nito C, Kamada H, Dodd RL, Hsieh LB, Hassid B, Kim EE, Gonzalez M, Chan PH. Oxidative stress and neuronal death/survival signaling in cerebral ischemia. Mol Neurobiol. 2005; 31(1-3): 105-16.
30. Sakai H, Sheng H, Yates RB, Ishida K, Pearlstein RD, Warner DS. Isoflurane provides long-term protection against focal cerebral ischemia in the rat. Anesthesiology. 2007; 106: 92-9. discussion 8-10.
31. Sheldon RA, Sedik C, Ferriero DM. Strain-related brain injury in neonatal mice subjected to hypoxia-ischemia. Brain Res. 1998; 810(1-2): 114-22.
32. Sheng H, Laskowitz DT, Pearlstein RD, Warner DS. Characterization of a recovery global cerebral ischemia model in the mouse. J Neurosci Methods. 1999; 88(1): 103-9.
33. Smith ML, Auer RN, Siesjo BK. The density and distribution of ischemic brain injury in the rat following 2-10 min of forebrain ischemia. Acta Neuropathol. 1984; 64(4): 319-32.
34. Smith ML, Bendek G, Dahlgren N, Rosen I, Wieloch T, Siesjo BK. Models for studying long-term recovery following forebrain ischemia in the rat. 2. A 2-vessel occlusion model. Acta Neurol Scand. 1984; 69(6): 385-401.
35. Wang J, Jin H, Hua Y, Keep RF, Xi G. Role of protease-activated receptor-1 in brain injury after experimental global cerebral ischemia. Stroke. 2012; 43: 2476-82.
36. Wellons 3rd JC, Sheng H, Laskowitz DT, Burkhard Mackensen G, Pearlstein RD, Warner DS. A comparison of strain-related susceptibility in two murine recovery models of global cerebral ischemia. Brain Res. 2000; 868(1): 14-21.
37. Yang G, Kitagawa K, Matsushita K, Mabuchi T, Yagita Y, Yanagihara T, Matsumoto M. C57BL/6 strain is most susceptible to cerebral ischemia following bilateral common carotid occlusion among seven mouse strains: selective neuronal death in the murine transient forebrain ischemia. Brain Res. 1997; 752(1-2): 209-18.
38. Yonekura I, Kawahara N, Nakatomi H, Furuya K, Kirino T. A model of global cerebral ischemia in C57 BL/6 mice. J Cereb Blood Flow Metab. 2004; 24(2): 151-8.
39. Zanelli SA, Solenski NJ, Rosenthal RE, Fiskum G. Mechanisms of ischemic neuroprotection by acetyl-L-carnitine. Ann N Y Acad Sci. 2005; 1053: 153-61.
40. Zhen G, Dore S. Optimized protocol to reduce variable outcomes for the bilateral common carotid artery occlusion model in mice. J Neurosci Methods. 2007; 166(1): 73-80.