Investigation and mathematical description of the real driving force of passive transport of drug molecules from supersaturated solutions

Molecular Pharmaceutics

Volumn 13, Issue 11, 2016, Pages 3816-3826

  Borbás, Eniko ^a   Sinkó, Bálint ^b   Tsinman, Oksana ^b   Tsinman, Konstantin ^b   Kiserdei, Éva ^a   Démuth, Balázs ^a   Balogh, Attila ^a   Bodák, Brigitta ^a   Domokos, András ^a   Dargó, Gergo ^a,c   Balogh, György T ^c   Nagy, Zsombor K ^a  

^a BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

^b PION INC   (United States)

^c GEDEON RICHTER LTD   (Hungary)

Author keywords

cosolvent; DMSO; electrospinning; flux; in vitro dissolution permeation test; meloxicam; microflux; nanofiber; Soluplus; supersaturation

Indexed keywords

MELOXICAM; POVIDONE DERIVATIVE; BETA CYCLODEXTRIN DERIVATIVE; DIMETHYL SULFOXIDE; MACROGOL DERIVATIVE; NANOFIBER; POLYMER; POLYVINYL CAPROLACTAM-POLYVINYL ACETATE-POLYETHYLENE GLYCOL GRAFT COPOLYMER; POLYVINYL DERIVATIVE; POVIDONE; SOLUTION AND SOLUBILITY; THIAZINE DERIVATIVE; THIAZOLE DERIVATIVE;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG FORMULATION; DRUG PENETRATION; DRUG SOLUBILITY; DRUG TRANSPORT; ELECTROSPINNING; FORCE; IN VITRO STUDY; MATHEMATICAL ANALYSIS; MEMBRANE TRANSPORT; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; THERMODYNAMICS; THERMOGRAPHY; X RAY POWDER DIFFRACTION; CHEMICAL STRUCTURE; CHEMISTRY; SOLUTION AND SOLUBILITY; THEORETICAL MODEL;

BETA-CYCLODEXTRINS; DIMETHYL SULFOXIDE; MODELS, THEORETICAL; MOLECULAR STRUCTURE; NANOFIBERS; POLYETHYLENE GLYCOLS; POLYMERS; POLYVINYLS; POVIDONE; SOLUTIONS; THIAZINES; THIAZOLES;

EID: 84994519350     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/acs.molpharmaceut.6b00613     Document Type: Article

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