Plasticized drug-loaded melt electrospun polymer mats: Characterization, thermal degradation, and release kinetics

Journal of Pharmaceutical Sciences

Volumn 103, Issue 4, 2014, Pages 1278-1287

  Balogh, Attila ^a   Drávavölgyi, Gábor ^a   Faragó, Kornél ^a   Farkas, Attila ^a   Vigh, Tamás ^a   Sóti, Péter Lajos ^a   Wagner, István ^a   Madarász, János ^a   Pataki, Hajnalka ^a   Marosi, György ^a   Nagy, Zsombor Kristóf ^a  

^a BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

Author keywords

amorphous; enhanced dissolution rate; extrusion; HPLC; melt electrospinning; oral drug delivery; plasticizer; Raman spectroscopy; solid dispersion; viscosity

Indexed keywords

CARVEDILOL; EUDRAGIT; MACROGOL; MACROGOL 1500; METHACRYLIC ACID; PLASTICIZER; POLYMER; POLYSORBATE 80; TRIACETIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DEGRADATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG MANUFACTURE; DRUG SOLUBILITY; DRUG STABILITY; DRUG STORAGE; DRUG STRUCTURE; ELECTROSPINNING; FLOW KINETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LOW TEMPERATURE; MELT ELECTROSPINNING; MELT EXTRUSION; MELTING POINT; MORPHOLOGY; PHYSICAL CHEMISTRY; PROCESS OPTIMIZATION; RAMAN SPECTROMETRY; SCANNING ELECTRON MICROSCOPY; X RAY DIFFRACTION;

AMORPHOUS; ENHANCED DISSOLUTION RATE; EXTRUSION; HPLC; MELT ELECTROSPINNING; ORAL DRUG DELIVERY; PLASTICIZER; RAMAN SPECTROSCOPY; SOLID DISPERSION; VISCOSITY;

ANTIHYPERTENSIVE AGENTS; CARBAZOLES; DRUG DELIVERY SYSTEMS; DRUG STABILITY; PLASTICIZERS; POLYMETHACRYLIC ACIDS; PROPANOLAMINES; SOLUBILITY; TEMPERATURE;

EID: 84896403118     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23904     Document Type: Article

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