메뉴 건너뛰기




Volumn 27, Issue 2, 2017, Pages 151-162

Disassembly of the Dying: Mechanisms and Functions

Author keywords

apoptosis; apoptotic bodies; cell clearance

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; MICRORNA; MYOSIN ADENOSINE TRIPHOSPHATASE; NOCODAZOLE; PROTEIN;

EID: 84994496697     PISSN: 09628924     EISSN: 18793088     Source Type: Journal    
DOI: 10.1016/j.tcb.2016.08.011     Document Type: Review
Times cited : (157)

References (82)
  • 1
    • 84935896741 scopus 로고    scopus 로고
    • A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure
    • 1 Atkin-Smith, G.K., et al. A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure. Nat. Commun., 6, 2015, 7439.
    • (2015) Nat. Commun. , vol.6 , pp. 7439
    • Atkin-Smith, G.K.1
  • 2
    • 84874355076 scopus 로고    scopus 로고
    • Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies
    • 2 Akers, J.C., et al. Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies. J. Neurooncol. 113 (2013), 1–11.
    • (2013) J. Neurooncol. , vol.113 , pp. 1-11
    • Akers, J.C.1
  • 3
    • 0015383455 scopus 로고
    • Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
    • 3 Kerr, J.F., et al. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26 (1972), 239–257.
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1
  • 4
    • 78650889847 scopus 로고    scopus 로고
    • Cellular mechanisms underlying the formation of circulating microparticles
    • 4 Morel, O., et al. Cellular mechanisms underlying the formation of circulating microparticles. Arterioscler. Thromb. Vasc. Biol. 31 (2011), 15–26.
    • (2011) Arterioscler. Thromb. Vasc. Biol. , vol.31 , pp. 15-26
    • Morel, O.1
  • 5
    • 0142122248 scopus 로고    scopus 로고
    • Microparticles in cardiovascular diseases
    • 5 VanWijk, M.J., et al. Microparticles in cardiovascular diseases. Cardiovasc. Res. 59 (2003), 277–287.
    • (2003) Cardiovasc. Res. , vol.59 , pp. 277-287
    • VanWijk, M.J.1
  • 6
    • 0036676445 scopus 로고    scopus 로고
    • Exosomes: composition, biogenesis and function
    • 6 Thery, C., et al. Exosomes: composition, biogenesis and function. Nat. Rev. Immunol. 2 (2002), 569–579.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 569-579
    • Thery, C.1
  • 7
    • 0032498625 scopus 로고    scopus 로고
    • Apoptotic membrane blebbing is regulated by myosin light chain phosphorylation
    • 7 Mills, J.C., et al. Apoptotic membrane blebbing is regulated by myosin light chain phosphorylation. J. Cell Biol. 140 (1998), 627–636.
    • (1998) J. Cell Biol. , vol.140 , pp. 627-636
    • Mills, J.C.1
  • 8
    • 33745505525 scopus 로고    scopus 로고
    • A novel role for microtubules in apoptotic chromatin dynamics and cellular fragmentation
    • 8 Moss, D.K., et al. A novel role for microtubules in apoptotic chromatin dynamics and cellular fragmentation. J. Cell Sci. 119 (2006), 2362–2374.
    • (2006) J. Cell Sci. , vol.119 , pp. 2362-2374
    • Moss, D.K.1
  • 9
    • 84897897084 scopus 로고    scopus 로고
    • Unexpected link between an antibiotic, pannexin channels and apoptosis
    • 9 Poon, I.K., et al. Unexpected link between an antibiotic, pannexin channels and apoptosis. Nature 507 (2014), 329–334.
    • (2014) Nature , vol.507 , pp. 329-334
    • Poon, I.K.1
  • 10
    • 84896690342 scopus 로고    scopus 로고
    • Apoptotic cell clearance: basic biology and therapeutic potential
    • 10 Poon, I.K., et al. Apoptotic cell clearance: basic biology and therapeutic potential. Nat. Rev. Immunol. 14 (2014), 166–180.
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 166-180
    • Poon, I.K.1
  • 11
    • 77951971046 scopus 로고    scopus 로고
    • The role of defective clearance of apoptotic cells in systemic autoimmunity
    • 11 Munoz, L.E., et al. The role of defective clearance of apoptotic cells in systemic autoimmunity. Nat. Rev. Rheumatol. 6 (2010), 280–289.
    • (2010) Nat. Rev. Rheumatol. , vol.6 , pp. 280-289
    • Munoz, L.E.1
  • 12
    • 27944440183 scopus 로고    scopus 로고
    • Rho kinase regulates fragmentation and phagocytosis of apoptotic cells
    • 12 Orlando, K.A., et al. Rho kinase regulates fragmentation and phagocytosis of apoptotic cells. Exp. Cell Res. 312 (2006), 5–15.
    • (2006) Exp. Cell Res. , vol.312 , pp. 5-15
    • Orlando, K.A.1
  • 13
    • 77449127999 scopus 로고    scopus 로고
    • Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection
    • 13 Zernecke, A., et al. Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection. Sci. Signal., 2, 2009, ra81.
    • (2009) Sci. Signal. , vol.2 , pp. ra81
    • Zernecke, A.1
  • 14
    • 0033152288 scopus 로고    scopus 로고
    • Horizontal transfer of DNA by the uptake of apoptotic bodies
    • 14 Holmgren, L., et al. Horizontal transfer of DNA by the uptake of apoptotic bodies. Blood 93 (1999), 3956–3963.
    • (1999) Blood , vol.93 , pp. 3956-3963
    • Holmgren, L.1
  • 15
    • 0021961178 scopus 로고
    • Radiation-induced formation of apoptotic bodies in rat thymus
    • 15 Ohyama, H., et al. Radiation-induced formation of apoptotic bodies in rat thymus. Radiat. Res. 101 (1985), 123–130.
    • (1985) Radiat. Res. , vol.101 , pp. 123-130
    • Ohyama, H.1
  • 16
    • 84930664806 scopus 로고    scopus 로고
    • Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool
    • 16 Mesa, K.R., et al. Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool. Nature 522 (2015), 94–97.
    • (2015) Nature , vol.522 , pp. 94-97
    • Mesa, K.R.1
  • 17
    • 84882844694 scopus 로고    scopus 로고
    • The role and regulation of blebs in cell migration
    • 17 Paluch, E.K., Raz, E., The role and regulation of blebs in cell migration. Curr. Opin. Cell Biol. 25 (2013), 582–590.
    • (2013) Curr. Opin. Cell Biol. , vol.25 , pp. 582-590
    • Paluch, E.K.1    Raz, E.2
  • 18
    • 84877775057 scopus 로고    scopus 로고
    • Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion
    • 18 Hochreiter-Hufford, A.E., et al. Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion. Nature 497 (2013), 263–267.
    • (2013) Nature , vol.497 , pp. 263-267
    • Hochreiter-Hufford, A.E.1
  • 19
    • 19644375086 scopus 로고    scopus 로고
    • Non-equilibration of hydrostatic pressure in blebbing cells
    • 19 Charras, G.T., et al. Non-equilibration of hydrostatic pressure in blebbing cells. Nature 435 (2005), 365–369.
    • (2005) Nature , vol.435 , pp. 365-369
    • Charras, G.T.1
  • 20
    • 0035075597 scopus 로고    scopus 로고
    • Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing
    • 20 Sebbagh, M., et al. Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing. Nat. Cell Biol. 3 (2001), 346–352.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 346-352
    • Sebbagh, M.1
  • 21
    • 0038650965 scopus 로고    scopus 로고
    • Apoptotic and necrotic blebs in epithelial cells display similar neck diameters but different kinase dependency
    • 21 Barros, L.F., et al. Apoptotic and necrotic blebs in epithelial cells display similar neck diameters but different kinase dependency. Cell Death Differ. 10 (2003), 687–697.
    • (2003) Cell Death Differ. , vol.10 , pp. 687-697
    • Barros, L.F.1
  • 22
    • 0035072953 scopus 로고    scopus 로고
    • Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I
    • 22 Coleman, M.L., et al. Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I. Nat. Cell Biol. 3 (2001), 339–345.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 339-345
    • Coleman, M.L.1
  • 23
    • 84883814455 scopus 로고    scopus 로고
    • Blebs produced by actin-myosin contraction during apoptosis release damage-associated molecular pattern proteins before secondary necrosis occurs
    • 23 Wickman, G.R., et al. Blebs produced by actin-myosin contraction during apoptosis release damage-associated molecular pattern proteins before secondary necrosis occurs. Cell Death Differ. 20 (2013), 1293–1305.
    • (2013) Cell Death Differ. , vol.20 , pp. 1293-1305
    • Wickman, G.R.1
  • 24
    • 84857395728 scopus 로고    scopus 로고
    • Matrix-bound PAI-1 supports cell blebbing via RhoA/ROCK1 signaling
    • 24 Cartier-Michaud, A., et al. Matrix-bound PAI-1 supports cell blebbing via RhoA/ROCK1 signaling. PLoS One, 7, 2012, e32204.
    • (2012) PLoS One , vol.7 , pp. e32204
    • Cartier-Michaud, A.1
  • 25
    • 3042858915 scopus 로고    scopus 로고
    • Caspase-mediated cleavage and activation of LIM-kinase 1 and its role in apoptotic membrane blebbing
    • 25 Tomiyoshi, G., et al. Caspase-mediated cleavage and activation of LIM-kinase 1 and its role in apoptotic membrane blebbing. Genes Cells 9 (2004), 591–600.
    • (2004) Genes Cells , vol.9 , pp. 591-600
    • Tomiyoshi, G.1
  • 26
    • 0032565769 scopus 로고    scopus 로고
    • Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization
    • 26 Yang, N., et al. Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization. Nature 393 (1998), 809–812.
    • (1998) Nature , vol.393 , pp. 809-812
    • Yang, N.1
  • 27
    • 0032565962 scopus 로고    scopus 로고
    • Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase
    • 27 Arber, S., et al. Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase. Nature 393 (1998), 805–809.
    • (1998) Nature , vol.393 , pp. 805-809
    • Arber, S.1
  • 28
    • 0030918572 scopus 로고    scopus 로고
    • Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2
    • 28 Rudel, T., Bokoch, G.M., Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. Science 276 (1997), 1571–1574.
    • (1997) Science , vol.276 , pp. 1571-1574
    • Rudel, T.1    Bokoch, G.M.2
  • 29
    • 34250021123 scopus 로고    scopus 로고
    • The apoptotic microtubule network preserves plasma membrane integrity during the execution phase of apoptosis
    • 29 Sanchez-Alcazar, J.A., et al. The apoptotic microtubule network preserves plasma membrane integrity during the execution phase of apoptosis. Apoptosis 12 (2007), 1195–1208.
    • (2007) Apoptosis , vol.12 , pp. 1195-1208
    • Sanchez-Alcazar, J.A.1
  • 30
    • 0030465874 scopus 로고    scopus 로고
    • Actin polymerization and depolymerization during apoptosis in HL-60 cells
    • 30 Levee, M.G., et al. Actin polymerization and depolymerization during apoptosis in HL-60 cells. Am. J. Physiol. 271 (1996), C1981–C1992.
    • (1996) Am. J. Physiol. , vol.271 , pp. C1981-C1992
    • Levee, M.G.1
  • 31
    • 26244439708 scopus 로고    scopus 로고
    • Active relocation of chromatin and endoplasmic reticulum into blebs in late apoptotic cells
    • 31 Lane, J.D., et al. Active relocation of chromatin and endoplasmic reticulum into blebs in late apoptotic cells. J. Cell Sci. 118 (2005), 4059–4071.
    • (2005) J. Cell Sci. , vol.118 , pp. 4059-4071
    • Lane, J.D.1
  • 32
    • 77957942834 scopus 로고    scopus 로고
    • Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
    • 32 Chekeni, F.B., et al. Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis. Nature 467 (2010), 863–867.
    • (2010) Nature , vol.467 , pp. 863-867
    • Chekeni, F.B.1
  • 33
    • 70249090374 scopus 로고    scopus 로고
    • Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
    • 33 Elliott, M.R., et al. Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance. Nature 461 (2009), 282–286.
    • (2009) Nature , vol.461 , pp. 282-286
    • Elliott, M.R.1
  • 34
    • 84962240485 scopus 로고    scopus 로고
    • Monitoring the progression of cell death and the disassembly of dying cells by flow cytometry
    • 34 Jiang, L., et al. Monitoring the progression of cell death and the disassembly of dying cells by flow cytometry. Nat. Protoc. 11 (2016), 655–663.
    • (2016) Nat. Protoc. , vol.11 , pp. 655-663
    • Jiang, L.1
  • 35
    • 80053475754 scopus 로고    scopus 로고
    • The P2X7 receptor and Pannexin-1 are both required for the promotion of multinucleated macrophages by the inflammatory cytokine GM-CSF
    • 35 Lemaire, I., et al. The P2X7 receptor and Pannexin-1 are both required for the promotion of multinucleated macrophages by the inflammatory cytokine GM-CSF. J. Immunol. 187 (2011), 3878–3887.
    • (2011) J. Immunol. , vol.187 , pp. 3878-3887
    • Lemaire, I.1
  • 36
    • 67650546999 scopus 로고    scopus 로고
    • The pannexin 1 channel activates the inflammasome in neurons and astrocytes
    • 36 Silverman, W.R., et al. The pannexin 1 channel activates the inflammasome in neurons and astrocytes. J. Biol. Chem. 284 (2009), 18143–18151.
    • (2009) J. Biol. Chem. , vol.284 , pp. 18143-18151
    • Silverman, W.R.1
  • 37
    • 55649113607 scopus 로고    scopus 로고
    • Purinergic control of T cell activation by ATP released through pannexin-1 hemichannels
    • 37 Schenk, U., et al. Purinergic control of T cell activation by ATP released through pannexin-1 hemichannels. Sci. Signal., 1, 2008, ra6.
    • (2008) Sci. Signal. , vol.1 , pp. ra6
    • Schenk, U.1
  • 38
    • 84947441282 scopus 로고    scopus 로고
    • Caspase-11 requires the pannexin-1 channel and the purinergic P2X7 pore to mediate pyroptosis and endotoxic shock
    • 38 Yang, D., et al. Caspase-11 requires the pannexin-1 channel and the purinergic P2X7 pore to mediate pyroptosis and endotoxic shock. Immunity 43 (2015), 923–932.
    • (2015) Immunity , vol.43 , pp. 923-932
    • Yang, D.1
  • 39
    • 0035933154 scopus 로고    scopus 로고
    • Horizontal transfer of oncogenes by uptake of apoptotic bodies
    • 39 Bergsmedh, A., et al. Horizontal transfer of oncogenes by uptake of apoptotic bodies. Proc. Natl. Acad. Sci. U. S. A. 98 (2001), 6407–6411.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 6407-6411
    • Bergsmedh, A.1
  • 40
    • 80052035289 scopus 로고    scopus 로고
    • Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice
    • 40 Turiak, L., et al. Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice. J. Proteomics 74 (2011), 2025–2033.
    • (2011) J. Proteomics , vol.74 , pp. 2025-2033
    • Turiak, L.1
  • 42
    • 78349243311 scopus 로고    scopus 로고
    • Cytoskeletal mechanics of proplatelet maturation and platelet release
    • 42 Thon, J.N., et al. Cytoskeletal mechanics of proplatelet maturation and platelet release. J. Cell Biol. 191 (2010), 861–874.
    • (2010) J. Cell Biol. , vol.191 , pp. 861-874
    • Thon, J.N.1
  • 43
    • 0035960736 scopus 로고    scopus 로고
    • An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin- and myosin-dependent mechanism
    • 43 Rosenblatt, J., et al. An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin- and myosin-dependent mechanism. Curr. Biol. 11 (2001), 1847–1857.
    • (2001) Curr. Biol. , vol.11 , pp. 1847-1857
    • Rosenblatt, J.1
  • 44
    • 76749086068 scopus 로고    scopus 로고
    • Molecular mechanisms of late apoptotic/necrotic cell clearance
    • 44 Poon, I.K., et al. Molecular mechanisms of late apoptotic/necrotic cell clearance. Cell Death Differ. 17 (2010), 381–397.
    • (2010) Cell Death Differ. , vol.17 , pp. 381-397
    • Poon, I.K.1
  • 45
    • 20144363054 scopus 로고    scopus 로고
    • Phagocytosis of apoptotic cells by macrophages is impaired in atherosclerosis
    • 45 Schrijvers, D.M., et al. Phagocytosis of apoptotic cells by macrophages is impaired in atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 25 (2005), 1256–1261.
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , pp. 1256-1261
    • Schrijvers, D.M.1
  • 46
    • 66349092815 scopus 로고    scopus 로고
    • Mechanisms and consequences of macrophage apoptosis in atherosclerosis
    • 46 Seimon, T., Tabas, I., Mechanisms and consequences of macrophage apoptosis in atherosclerosis. J. Lipid Res. 50:Suppl. (2009), S382–S387.
    • (2009) J. Lipid Res. , vol.50 , pp. S382-S387
    • Seimon, T.1    Tabas, I.2
  • 47
    • 0036164008 scopus 로고    scopus 로고
    • Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus
    • 47 Baumann, I., et al. Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus. Arthritis Rheum. 46 (2002), 191–201.
    • (2002) Arthritis Rheum. , vol.46 , pp. 191-201
    • Baumann, I.1
  • 48
    • 2442665179 scopus 로고    scopus 로고
    • Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice
    • 48 Hanayama, R., et al. Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice. Science 304 (2004), 1147–1150.
    • (2004) Science , vol.304 , pp. 1147-1150
    • Hanayama, R.1
  • 49
    • 0036645294 scopus 로고    scopus 로고
    • Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase
    • 49 Cohen, P.L., et al. Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase. J. Exp. Med. 196 (2002), 135–140.
    • (2002) J. Exp. Med. , vol.196 , pp. 135-140
    • Cohen, P.L.1
  • 50
    • 36248944555 scopus 로고    scopus 로고
    • Identification of Tim4 as a phosphatidylserine receptor
    • 50 Miyanishi, M., et al. Identification of Tim4 as a phosphatidylserine receptor. Nature 450 (2007), 435–439.
    • (2007) Nature , vol.450 , pp. 435-439
    • Miyanishi, M.1
  • 51
    • 0034604029 scopus 로고    scopus 로고
    • A receptor for phosphatidylserine-specific clearance of apoptotic cells
    • 51 Fadok, V.A., et al. A receptor for phosphatidylserine-specific clearance of apoptotic cells. Nature 405 (2000), 85–90.
    • (2000) Nature , vol.405 , pp. 85-90
    • Fadok, V.A.1
  • 52
    • 36248987290 scopus 로고    scopus 로고
    • BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module
    • 52 Park, D., et al. BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module. Nature 450 (2007), 430–434.
    • (2007) Nature , vol.450 , pp. 430-434
    • Park, D.1
  • 53
    • 34247401712 scopus 로고    scopus 로고
    • Bridge over troubled water: milk fat globule epidermal growth factor 8 promotes human monocyte-derived macrophage clearance of non-blebbing phosphatidylserine-positive target cells
    • 53 Witasp, E., et al. Bridge over troubled water: milk fat globule epidermal growth factor 8 promotes human monocyte-derived macrophage clearance of non-blebbing phosphatidylserine-positive target cells. Cell Death Differ. 14 (2007), 1063–1065.
    • (2007) Cell Death Differ. , vol.14 , pp. 1063-1065
    • Witasp, E.1
  • 54
    • 0026545368 scopus 로고
    • The macrophage capacity for phagocytosis
    • 54 Cannon, G.J., Swanson, J.A., The macrophage capacity for phagocytosis. J. Cell Sci. 101 (1992), 907–913.
    • (1992) J. Cell Sci. , vol.101 , pp. 907-913
    • Cannon, G.J.1    Swanson, J.A.2
  • 55
    • 0038476330 scopus 로고    scopus 로고
    • Apoptotic body engulfment by a human stellate cell line is profibrogenic
    • 55 Canbay, A., et al. Apoptotic body engulfment by a human stellate cell line is profibrogenic. Lab. Invest. 83 (2003), 655–663.
    • (2003) Lab. Invest. , vol.83 , pp. 655-663
    • Canbay, A.1
  • 56
    • 0035837323 scopus 로고    scopus 로고
    • Phagocytosis and clearance of apoptotic cells is mediated by MER
    • 56 Scott, R.S., et al. Phagocytosis and clearance of apoptotic cells is mediated by MER. Nature 411 (2001), 207–211.
    • (2001) Nature , vol.411 , pp. 207-211
    • Scott, R.S.1
  • 57
    • 0031778836 scopus 로고    scopus 로고
    • Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies
    • 57 Botto, M., et al. Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies. Nat. Genet. 19 (1998), 56–59.
    • (1998) Nat. Genet. , vol.19 , pp. 56-59
    • Botto, M.1
  • 58
    • 0033947551 scopus 로고    scopus 로고
    • C1q: structure, function, and receptors
    • 58 Kishore, U., Reid, K.B., C1q: structure, function, and receptors. Immunopharmacology 49 (2000), 159–170.
    • (2000) Immunopharmacology , vol.49 , pp. 159-170
    • Kishore, U.1    Reid, K.B.2
  • 59
    • 52449097275 scopus 로고    scopus 로고
    • Defective mer receptor tyrosine kinase signaling in bone marrow cells promotes apoptotic cell accumulation and accelerates atherosclerosis
    • 59 Ait-Oufella, H., et al. Defective mer receptor tyrosine kinase signaling in bone marrow cells promotes apoptotic cell accumulation and accelerates atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 28 (2008), 1429–1431.
    • (2008) Arterioscler. Thromb. Vasc. Biol. , vol.28 , pp. 1429-1431
    • Ait-Oufella, H.1
  • 60
    • 41749091574 scopus 로고    scopus 로고
    • Applications for ROCK kinase inhibition
    • 60 Olson, M.F., Applications for ROCK kinase inhibition. Curr. Opin. Cell Biol., 20, 2008, 7.
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 7
    • Olson, M.F.1
  • 61
    • 84961926636 scopus 로고    scopus 로고
    • Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis
    • 61 Kümper, S., et al. Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis. Elife, 5, 2016, e12994.
    • (2016) Elife , vol.5 , pp. e12994
    • Kümper, S.1
  • 62
    • 84938931625 scopus 로고    scopus 로고
    • Pannexin 1 channels regulate leukocyte emigration through the venous endothelium during acute inflammation
    • 62 Lohman, A.W., et al. Pannexin 1 channels regulate leukocyte emigration through the venous endothelium during acute inflammation. Nat. Commun., 6, 2015, 7965.
    • (2015) Nat. Commun. , vol.6 , pp. 7965
    • Lohman, A.W.1
  • 63
    • 84902533320 scopus 로고    scopus 로고
    • Panx1 regulates cellular properties of keratinocytes and dermal fibroblasts in skin development and wound healing
    • 63 Penuela, S., et al. Panx1 regulates cellular properties of keratinocytes and dermal fibroblasts in skin development and wound healing. J. Invest. Dermatol. 134 (2014), 2026–2035.
    • (2014) J. Invest. Dermatol. , vol.134 , pp. 2026-2035
    • Penuela, S.1
  • 64
    • 0347379920 scopus 로고    scopus 로고
    • Engulfment of apoptotic cells is negatively regulated by Rho-mediated signaling
    • 64 Tosello-Trampont, A.C., et al. Engulfment of apoptotic cells is negatively regulated by Rho-mediated signaling. J. Biol. Chem. 278 (2003), 49911–49919.
    • (2003) J. Biol. Chem. , vol.278 , pp. 49911-49919
    • Tosello-Trampont, A.C.1
  • 65
    • 84898735135 scopus 로고    scopus 로고
    • Immunosuppression via adenosine receptor activation by adenosine monophosphate released from apoptotic cells
    • 65 Yamaguchi, H., et al. Immunosuppression via adenosine receptor activation by adenosine monophosphate released from apoptotic cells. Elife, 3, 2014, e02172.
    • (2014) Elife , vol.3 , pp. e02172
    • Yamaguchi, H.1
  • 66
    • 84870474671 scopus 로고    scopus 로고
    • Dissecting T cell contraction in vivo using a genetically encoded reporter of apoptosis
    • 66 Garrod, K.R., et al. Dissecting T cell contraction in vivo using a genetically encoded reporter of apoptosis. Cell Rep. 2 (2012), 1438–1447.
    • (2012) Cell Rep. , vol.2 , pp. 1438-1447
    • Garrod, K.R.1
  • 67
    • 84872870688 scopus 로고    scopus 로고
    • Histology of intestinal allografts: lymphocyte apoptosis and phagocytosis of lymphocytic apoptotic bodies are diagnostic findings of acute rejection in addition to crypt apoptosis
    • 67 Tsuruyama, T., et al. Histology of intestinal allografts: lymphocyte apoptosis and phagocytosis of lymphocytic apoptotic bodies are diagnostic findings of acute rejection in addition to crypt apoptosis. Am. J. Surg. Pathol. 37 (2013), 178–184.
    • (2013) Am. J. Surg. Pathol. , vol.37 , pp. 178-184
    • Tsuruyama, T.1
  • 68
    • 84924971858 scopus 로고    scopus 로고
    • Exosomes and other extracellular vesicles in host-pathogen interactions
    • 68 Schorey, J.S., et al. Exosomes and other extracellular vesicles in host-pathogen interactions. EMBO Rep. 16 (2015), 24–43.
    • (2015) EMBO Rep. , vol.16 , pp. 24-43
    • Schorey, J.S.1
  • 69
    • 84901947865 scopus 로고    scopus 로고
    • Emerging role of extracellular vesicles in inflammatory diseases
    • 69 Buzas, E.I., et al. Emerging role of extracellular vesicles in inflammatory diseases. Nat. Rev. Rheumatol. 10 (2014), 356–364.
    • (2014) Nat. Rev. Rheumatol. , vol.10 , pp. 356-364
    • Buzas, E.I.1
  • 70
    • 0036906477 scopus 로고    scopus 로고
    • + T cells by dendritic cell-derived exosomes
    • + T cells by dendritic cell-derived exosomes. Nat. Immunol. 3 (2002), 1156–1162.
    • (2002) Nat. Immunol. , vol.3 , pp. 1156-1162
    • Thery, C.1
  • 71
    • 84857975438 scopus 로고    scopus 로고
    • Microparticles: major transport vehicles for distinct microRNAs in circulation
    • 71 Diehl, P., et al. Microparticles: major transport vehicles for distinct microRNAs in circulation. Cardiovasc. Res. 93 (2012), 633–644.
    • (2012) Cardiovasc. Res. , vol.93 , pp. 633-644
    • Diehl, P.1
  • 72
    • 84887075238 scopus 로고    scopus 로고
    • Endothelial microparticle-mediated transfer of MicroRNA-126 promotes vascular endothelial cell repair via SPRED1 and is abrogated in glucose-damaged endothelial microparticles
    • 72 Jansen, F., et al. Endothelial microparticle-mediated transfer of MicroRNA-126 promotes vascular endothelial cell repair via SPRED1 and is abrogated in glucose-damaged endothelial microparticles. Circulation 128 (2013), 2026–2038.
    • (2013) Circulation , vol.128 , pp. 2026-2038
    • Jansen, F.1
  • 73
    • 0034329421 scopus 로고    scopus 로고
    • Segregation of RNA and separate packaging of DNA and RNA in apoptotic bodies during apoptosis
    • 73 Halicka, H.D., et al. Segregation of RNA and separate packaging of DNA and RNA in apoptotic bodies during apoptosis. Exp. Cell Res. 260 (2000), 248–256.
    • (2000) Exp. Cell Res. , vol.260 , pp. 248-256
    • Halicka, H.D.1
  • 74
    • 37349104035 scopus 로고    scopus 로고
    • Autoantigens are translocated into small apoptotic bodies during early stages of apoptosis
    • 74 Schiller, M., et al. Autoantigens are translocated into small apoptotic bodies during early stages of apoptosis. Cell Death Differ. 15 (2008), 183–191.
    • (2008) Cell Death Differ. , vol.15 , pp. 183-191
    • Schiller, M.1
  • 75
    • 0028288510 scopus 로고
    • Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes
    • 75 Casciola-Rosen, L.A., et al. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J. Exp. Med. 179 (1994), 1317–1330.
    • (1994) J. Exp. Med. , vol.179 , pp. 1317-1330
    • Casciola-Rosen, L.A.1
  • 76
    • 0036159163 scopus 로고    scopus 로고
    • Subcellular redistribution of la/SSB autoantigen during physiologic apoptosis in the fetal mouse heart and conduction system: a clue to the pathogenesis of congenital heart block
    • 76 Tran, H.B., et al. Subcellular redistribution of la/SSB autoantigen during physiologic apoptosis in the fetal mouse heart and conduction system: a clue to the pathogenesis of congenital heart block. Arthritis Rheum. 46 (2002), 202–208.
    • (2002) Arthritis Rheum. , vol.46 , pp. 202-208
    • Tran, H.B.1
  • 77
    • 84855504820 scopus 로고    scopus 로고
    • Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1alpha
    • 77 Berda-Haddad, Y., et al. Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1alpha. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), 20684–20689.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 20684-20689
    • Berda-Haddad, Y.1
  • 78
    • 84868131859 scopus 로고    scopus 로고
    • Tubular cell HIV-entry through apoptosed CD4 T cells: a novel pathway
    • 78 Singh, P., et al. Tubular cell HIV-entry through apoptosed CD4 T cells: a novel pathway. Virology 434 (2012), 68–77.
    • (2012) Virology , vol.434 , pp. 68-77
    • Singh, P.1
  • 79
    • 77957733643 scopus 로고    scopus 로고
    • Engulfment of cerebral apoptotic bodies controls the course of prion disease in a mouse strain-dependent manner
    • 79 Kranich, J., et al. Engulfment of cerebral apoptotic bodies controls the course of prion disease in a mouse strain-dependent manner. J. Exp. Med. 207 (2010), 2271–2281.
    • (2010) J. Exp. Med. , vol.207 , pp. 2271-2281
    • Kranich, J.1
  • 80
    • 77950430319 scopus 로고    scopus 로고
    • HIV and mature dendritic cells: Trojan exosomes riding the Trojan horse?
    • 80 Izquierdo-Useros, N., et al. HIV and mature dendritic cells: Trojan exosomes riding the Trojan horse?. PLoS Pathog., 6, 2010, e1000740.
    • (2010) PLoS Pathog. , vol.6 , pp. e1000740
    • Izquierdo-Useros, N.1
  • 81
    • 31444453892 scopus 로고    scopus 로고
    • Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection
    • 81 Wiley, R.D., Gummuluru, S., Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection. Proc. Natl. Acad. Sci. U. S. A. 103 (2006), 738–743.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 738-743
    • Wiley, R.D.1    Gummuluru, S.2
  • 82
    • 0032891440 scopus 로고    scopus 로고
    • Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity
    • 82 Mallat, Z., et al. Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity. Circulation 99 (1999), 348–353.
    • (1999) Circulation , vol.99 , pp. 348-353
    • Mallat, Z.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.