-
1
-
-
0035865682
-
LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505
-
Amano, T., Tanabe, K., Eto, T., Narumiya, S. & Mizuno, K. (2001) LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505. Biochem. J. 354, 149-159.
-
(2001)
Biochem. J.
, vol.354
, pp. 149-159
-
-
Amano, T.1
Tanabe, K.2
Eto, T.3
Narumiya, S.4
Mizuno, K.5
-
2
-
-
0032565962
-
Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase
-
Arber, S., Barbayannis, F.A., Hanser, H., et al. (1998) Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase. Nature 393, 805-809.
-
(1998)
Nature
, vol.393
, pp. 805-809
-
-
Arber, S.1
Barbayannis, F.A.2
Hanser, H.3
-
3
-
-
0033280237
-
Proteins of the ADF/cofilin family: Essential regulators of actin dynamics
-
Bamburg, J.R. (1999) Proteins of the ADF/cofilin family: essential regulators of actin dynamics. Annu. Rev. Cell Dev. Biol. 15, 185-230.
-
(1999)
Annu. Rev. Cell Dev. Biol.
, vol.15
, pp. 185-230
-
-
Bamburg, J.R.1
-
4
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp, T.R., Bernards, R. & Agami, R. (2002) A system for stable expression of short interfering RNAs in mammalian cells. Science 296, 550-553.
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
5
-
-
0033977699
-
Regulating actin-filament dynamics in vivo
-
Chen, H., Bernstein, B.W. & Bamburg, J.R. (2000) Regulating actin-filament dynamics in vivo. Trend Biochem. Sci. 25, 19-23.
-
(2000)
Trend Biochem. Sci.
, vol.25
, pp. 19-23
-
-
Chen, H.1
Bernstein, B.W.2
Bamburg, J.R.3
-
6
-
-
0035072953
-
Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I
-
Coleman, M.L., Sahai, E.A., Yeo, M., Bosch, M., Dewar, A. & Olson, M.F. (2001) Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I. Nature Cell Biol. 3, 339-345.
-
(2001)
Nature Cell Biol.
, vol.3
, pp. 339-345
-
-
Coleman, M.L.1
Sahai, E.A.2
Yeo, M.3
Bosch, M.4
Dewar, A.5
Olson, M.F.6
-
7
-
-
0026505081
-
Microfilament-disrupting agents prevent the formation of apoptotic bodies in tumor cells undergoing apoptosis
-
Cotter, T.G., Lennon, S.V., Glynn, J.M. & Green, D.R. (1992) Microfilament-disrupting agents prevent the formation of apoptotic bodies in tumor cells undergoing apoptosis. Cancer Res. 52, 997-1005.
-
(1992)
Cancer Res.
, vol.52
, pp. 997-1005
-
-
Cotter, T.G.1
Lennon, S.V.2
Glynn, J.M.3
Green, D.R.4
-
8
-
-
0033194037
-
Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signaling to actin cytoskeletal dynamics
-
Edwards, D.C., Sanders, L.C., Bokoch, G.M. & Gill, G.N. (1999) Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signaling to actin cytoskeletal dynamics. Nature Cell Biol. 1, 253-259.
-
(1999)
Nature Cell Biol.
, vol.1
, pp. 253-259
-
-
Edwards, D.C.1
Sanders, L.C.2
Bokoch, G.M.3
Gill, G.N.4
-
9
-
-
0025719085
-
Mechanisms and functions of cell death
-
Ellis, R.E., Yuan, J. & Horvitz, H.R. (1991) Mechanisms and functions of cell death. Annu. Rev. Cell Biol. 7, 663-698.
-
(1991)
Annu. Rev. Cell Biol.
, vol.7
, pp. 663-698
-
-
Ellis, R.E.1
Yuan, J.2
Horvitz, H.R.3
-
10
-
-
13344259987
-
Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells
-
Emoto, Y., Manome, Y., Meinhardt, G., et al. (1995) Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells. EMBO J. 14, 6148-6156.
-
(1995)
EMBO J.
, vol.14
, pp. 6148-6156
-
-
Emoto, Y.1
Manome, Y.2
Meinhardt, G.3
-
11
-
-
0030947095
-
Programmed cell death in animal development
-
Jacobson, M.D., Weil, M. & Raff, M.C. (1997) Programmed cell death in animal development. Cell 88, 347-354.
-
(1997)
Cell
, vol.88
, pp. 347-354
-
-
Jacobson, M.D.1
Weil, M.2
Raff, M.C.3
-
12
-
-
0032546795
-
Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis
-
Janicke, R.U., Ng, P., Sprengart, M.L. & Porter, A.G. (1998) Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis. J. Biol. Chem. 273, 15540-15545.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 15540-15545
-
-
Janicke, R.U.1
Ng, P.2
Sprengart, M.L.3
Porter, A.G.4
-
13
-
-
0029993727
-
Active and inactive protein kinases: Structural basis for regulation
-
Johnson, L.N., Noble, M.E. & Owen, D.J. (1996) Active and inactive protein kinases: structural basis for regulation. Cell 85, 149-158.
-
(1996)
Cell
, vol.85
, pp. 149-158
-
-
Johnson, L.N.1
Noble, M.E.2
Owen, D.J.3
-
14
-
-
0029891890
-
Bleb formation and F-actin distribution during mitosis and tumor necrosis factor-induced apoptosis
-
Laster, S.M. & Mackenzie, J.N. (1996) Bleb formation and F-actin distribution during mitosis and tumor necrosis factor-induced apoptosis. Microsc. Res. Techn. 34, 272-280.
-
(1996)
Microsc. Res. Techn.
, vol.34
, pp. 272-280
-
-
Laster, S.M.1
Mackenzie, J.N.2
-
15
-
-
0031443641
-
Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis
-
Lee, N., MacDonald, H., Reinhard, C., et al. (1997) Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis. Proc. Natl Acad Sci. USA 94, 13642-13647.
-
(1997)
Proc. Natl. Acad Sci. USA
, vol.94
, pp. 13642-13647
-
-
Lee, N.1
MacDonald, H.2
Reinhard, C.3
-
16
-
-
0032536543
-
Caspase-mediated cleavage of focal adhesion kinase pp125FAK and disassembly of focal adhesions in human endothelial cell apoptosis
-
Levkau, B., Herren, B., Koyama, H., Ross, R. & Raines, E.W. (1998) Caspase-mediated cleavage of focal adhesion kinase pp125FAK and disassembly of focal adhesions in human endothelial cell apoptosis. J. Exp. Med. 187, 579-586.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 579-586
-
-
Levkau, B.1
Herren, B.2
Koyama, H.3
Ross, R.4
Raines, E.W.5
-
17
-
-
0033529620
-
Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase
-
Maekawa, M., Ishizaki, T., Boku, S., et al. (1999) Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science 285, 895-898.
-
(1999)
Science
, vol.285
, pp. 895-898
-
-
Maekawa, M.1
Ishizaki, T.2
Boku, S.3
-
18
-
-
0032498625
-
Apoptotic membrane blebbing is regulated by myosin light chain phosphorylation
-
Mills, J.C., Stone, N.L., Erhardt, J. & Pittman, R.N. (1998) Apoptotic membrane blebbing is regulated by myosin light chain phosphorylation. J. Cell Biol. 140, 627-636.
-
(1998)
J. Cell Biol.
, vol.140
, pp. 627-636
-
-
Mills, J.C.1
Stone, N.L.2
Erhardt, J.3
Pittman, R.N.4
-
19
-
-
0028335706
-
Identification of a human cDNA encoding a novel protein kinase with two repeats of the LIM/double zinc finger motif
-
Mizuno, K., Okano, I., Ohashi, K., et al. (1994) Identification of a human cDNA encoding a novel protein kinase with two repeats of the LIM/double zinc finger motif. Oncogene 9, 1605-1612.
-
(1994)
Oncogene
, vol.9
, pp. 1605-1612
-
-
Mizuno, K.1
Okano, I.2
Ohashi, K.3
-
20
-
-
0033214096
-
The N-terminal LIM domain negatively regulates the kinase activity of LIM-kinase 1
-
Nagata, K., Ohashi, K., Yang, N. & Mizuno, K. (1999) The N-terminal LIM domain negatively regulates the kinase activity of LIM-kinase 1. Biochem. J. 343, 99-105.
-
(1999)
Biochem. J.
, vol.343
, pp. 99-105
-
-
Nagata, K.1
Ohashi, K.2
Yang, N.3
Mizuno, K.4
-
21
-
-
0036142414
-
Stromal cell-derived factor 1α activates LIM kinase 1 and induces cofilin phosphorylation for T-cell chemotaxis
-
Nishita, M., Aizawa, H. & Mizuno, K. (2002) Stromal cell-derived factor 1α activates LIM kinase 1 and induces cofilin phosphorylation for T-cell chemotaxis. Mol. Cell. Biol. 22, 774-783.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 774-783
-
-
Nishita, M.1
Aizawa, H.2
Mizuno, K.3
-
22
-
-
0034602959
-
Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop
-
Ohashi, K., Nagata, K., Maekawa, M., Ishizaki, T., Narumiya, S. & Mizuno, K. (2000) Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop. J. Biol. Chem. 275, 3577-3582.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 3577-3582
-
-
Ohashi, K.1
Nagata, K.2
Maekawa, M.3
Ishizaki, T.4
Narumiya, S.5
Mizuno, K.6
-
23
-
-
0029594144
-
Identification and characterization of a novel family of serine/threonine kinases containing two N-terminal LIM motifs
-
Okano, I., Hiraoka, H., Otera, H., et al. (1995) Identification and characterization of a novel family of serine/threonine kinases containing two N-terminal LIM motifs. J. Biol. Chem. 270, 31321-31330.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 31321-31330
-
-
Okano, I.1
Hiraoka, H.2
Otera, H.3
-
24
-
-
0008727013
-
Alterations of the actin polymerization status as an apoptotic morphological effector in HL-60 cells
-
Rao, J.Y., Jin, Y.S., Zheng, Q.L., Cheng, J., Tai, J. & Hemstreet, G.P. III (1999) Alterations of the actin polymerization status as an apoptotic morphological effector in HL-60 cells. J. Cell. Biochem. 75, 686-697.
-
(1999)
J. Cell Biochem.
, vol.75
, pp. 686-697
-
-
Rao, J.Y.1
Jin, Y.S.2
Zheng, Q.L.3
Cheng, J.4
Tai, J.5
Hemstreet III, G.P.6
-
25
-
-
0030918572
-
Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2
-
Rudel, T. & Bokoch, G.M. (1997) Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. Science 276, 1571-1574.
-
(1997)
Science
, vol.276
, pp. 1571-1574
-
-
Rudel, T.1
Bokoch, G.M.2
-
26
-
-
0030702084
-
Caspases: Intracellular signaling by proteolysis
-
Salvesen, G.S. & Dixit, V.M. (1997) Caspases: intracellular signaling by proteolysis. Cell 91, 443-446.
-
(1997)
Cell
, vol.91
, pp. 443-446
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
27
-
-
0035075597
-
Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing
-
Sebbagh, M., Renvoize, C., Hamelin, J., Riche, N., Bertoglio, J. & Breard, J. (2001) Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing. Nature Cell Biol. 3, 346-352.
-
(2001)
Nature Cell Biol.
, vol.3
, pp. 346-352
-
-
Sebbagh, M.1
Renvoize, C.2
Hamelin, J.3
Riche, N.4
Bertoglio, J.5
Breard, J.6
-
28
-
-
0032578393
-
Proteolytic activation of PKN by caspase-3 or related protease during apoptosis
-
Takahashi, M., Mukai, H., Toshimori, M., Miyamoto, M. & Ono, Y. (1998) Proteolytic activation of PKN by caspase-3 or related protease during apoptosis. Proc. Natl Acad. Sci. USA 95, 11566-11571.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 11566-11571
-
-
Takahashi, M.1
Mukai, H.2
Toshimori, M.3
Miyamoto, M.4
Ono, Y.5
-
29
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
Thompson, C.B. (1995) Apoptosis in the pathogenesis and treatment of disease. Science 267, 1456-1462.
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
30
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry, N.A. & Lazabnik, Y. (1998) Caspases: enemies within. Science 281, 1312-1316.
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazabnik, Y.2
-
31
-
-
0030849093
-
A combinatorial approach defines specificities of members of the caspase family and granzyme B: Functional relationships established for key mediators of apoptosis
-
Thornberry, N.A., Rano, T.A., Peterson, E.P., et al. (1997) A combinatorial approach defines specificities of members of the caspase family and granzyme B: functional relationships established for key mediators of apoptosis. J. Biol. Chem. 272, 17907-17911.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17907-17911
-
-
Thornberry, N.A.1
Rano, T.A.2
Peterson, E.P.3
-
32
-
-
0035171699
-
Cofilin phosphorylation by protein kinase TESK1 and its role in integrin-mediated actin reorganization and focal adhesion formation
-
Toshima, J., Toshima, J.Y., Amano, T., Yang, N., Narumiya, S. & Mizuno, K. (2001a) Cofilin phosphorylation by protein kinase TESK1 and its role in integrin-mediated actin reorganization and focal adhesion formation. Mol. Biol. Cell 12, 1131-1145.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 1131-1145
-
-
Toshima, J.1
Toshima, J.Y.2
Amano, T.3
Yang, N.4
Narumiya, S.5
Mizuno, K.6
-
33
-
-
0035903099
-
Cofilin phosphorylation and actin reorganization activities of testicular protein kinase 2 and its predominant expression in testicular Sertoli cells
-
Toshima, J., Toshima, J.Y., Takeuchi, K., Mori, R. & Mizuno, K. (2001b) Cofilin phosphorylation and actin reorganization activities of testicular protein kinase 2 and its predominant expression in testicular Sertoli cells. J. Biol. Chem. 276, 31449-31458.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 31449-31458
-
-
Toshima, J.1
Toshima, J.Y.2
Takeuchi, K.3
Mori, R.4
Mizuno, K.5
-
34
-
-
0030656619
-
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
-
Uehata, M., Ishizaki, T., Satoh, H., et al. (1997) Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 389, 990-994.
-
(1997)
Nature
, vol.389
, pp. 990-994
-
-
Uehata, M.1
Ishizaki, T.2
Satoh, H.3
-
35
-
-
0032565769
-
Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization
-
Yang, N., Higuchi, O., Ohashi, K., et al. (1998) Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization. Nature 393, 809-812.
-
(1998)
Nature
, vol.393
, pp. 809-812
-
-
Yang, N.1
Higuchi, O.2
Ohashi, K.3
-
36
-
-
0032506122
-
Caspase-3 controls both cytoplasmic and nuclear events associated with Fas-mediated apoptosis in vivo
-
Zheng, T.S., Schlosser, S.F., Dao, T., et al. (1998) Caspase-3 controls both cytoplasmic and nuclear events associated with Fas-mediated apoptosis in vivo. Proc. Natl Acad. Sci. USA 95, 13618-13623.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 13618-13623
-
-
Zheng, T.S.1
Schlosser, S.F.2
Dao, T.3
|