Liver fatty acid composition and inflammation in mice fed with high-carbohydrate diet or high-fat diet

Nutrients

Volumn 8, Issue 11, 2016, Pages

  da Silva Santi, Lorena Gimenez ^a   Antunes, Marina Masetto ^a   Caparroz Assef, Silvana Martins ^a   Carbonera, Fabiana ^a   Masi, Laureane Nunes ^b   Curi, Rui ^b   Visentainer, Jesuí Vergílio ^a   Bazotte, Roberto Barbosa ^a  

^a STATE UNIVERSITY OF MARINGÁ   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Desaturases; Elongases; Monounsaturated fatty acids; Myeloperoxidase; N 6 n 3 fatty acid ratio; Nitric oxide; Polyunsaturated fatty acids; Pro inflammatory cytokines; Saturated fatty acids

Indexed keywords

ACYL COENZYME A DESATURASE; ACYL COENZYME A DESATURASE 1; ARACHIDONIC ACID; COLLAGEN TYPE 1; FATTY ACID ESTER; HENEICOSANOIC ACID; HIPOGEIC ACID; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIGNOCERIC ACID; LINOLEIC ACID; LINOLENIC ACID; LINOLEOYL COENZYME A DESATURASE; LIVER ENZYME; MESSENGER RNA; MONOUNSATURATED FATTY ACID; MYELOPEROXIDASE; MYRISTIC ACID; NITRIC OXIDE; OLEIC ACID; OMEGA 3 FATTY ACID; PALMITIC ACID; PALMITOLEIC ACID; POLYUNSATURATED FATTY ACID; SATURATED FATTY ACID; STEARIC ACID; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; VACCENIC ACID; ACC1 PROTEIN, MOUSE; ACETYL COENZYME A CARBOXYLASE; ACYLTRANSFERASE; AUTACOID; BIOLOGICAL MARKER; DELTA-6 DESATURASE, MOUSE; FATTY ACID; FATTY ACID ELONGASES; SCD1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE DIET; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; INFLAMMATION; LIPID COMPOSITION; LIPID DIET; LIPID STORAGE; LIPOGENESIS; LIVER; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; ADVERSE EFFECTS; ANIMAL; CARBOHYDRATE LOADING DIET; COMPARATIVE STUDY; DISEASE COURSE; DISEASE MODEL; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; PATHOPHYSIOLOGY; RANDOMIZATION;

ACETYL-COA CARBOXYLASE; ACETYLTRANSFERASES; ANIMALS; BIOMARKERS; DIET, CARBOHYDRATE LOADING; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FATTY ACID DESATURASES; FATTY ACIDS; GENE EXPRESSION REGULATION; INFLAMMATION MEDIATORS; LIPOGENESIS; LIVER; MALE; MICE; NON-ALCOHOLIC FATTY LIVER DISEASE; RANDOM ALLOCATION; RNA, MESSENGER; STEAROYL-COA DESATURASE;

EID: 84994448338     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu8110682     Document Type: Article

References (52)

1. Loomba, R.; Sanyal, A.J. The global NAFLD epidemic. Nat. Rev. Gastroenterol. Hepatol. 2013, 10, 686–690.
2. Orci, L.A.; Gariani, K.; Oldani, G.; Delaune, V.; Morel, P.; Toso, C. Exercise-based interventions for non-alcoholic fatty liver disease: A meta-analysis and meta-regression. Clin. Gastroenterol. Hepatol. 2016, 14, 1398–1411.
3. Yki-Järvinen, H. Nutritional modulation of non-alcoholic fatty liver disease and insulin resistance. Nutrients 2015, 7, 9127–9138.
4. Sayiner, M.; Koenig, A.; Henry, L.; Younossi, Z.M. Epidemiology of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis in the United States and the rest of the world. Clin. Liver Dis. 2016, 20, 205–214.
5. Bazotte, R.B.; Silva, L.G.; Schiavon, F.P.M. Insulin resistance in the liver: Deficiency or excess of insulin? Cell Cycle 2014, 13, 2494–2500.
6. Zelber-Sagi, S.; Salomone, F.; Yeshua, H.; Lotan, R.; Webb, M.; Halpern, Z.; Santo, E.; Oren, R.; Shibolet, O. Non-high-density lipoprotein cholesterol independently predicts new onset of non-alcoholic fatty liver disease. Liver Int. 2014, 34, e128–e135.
7. Targher, G.; Byrne, C.D.; Lonardo, A.; Zoppini, G.; Barbui, C. Nonalcoholic fatty liver disease and risk of incident cardiovascular disease: A meta-analysis of observational studies. J. Hepatol. 2016, 65, 589–600.
8. Moore, J.B.; Gunn, P.J.; Fielding, B.A. The role of dietary sugars and de novo lipogenesis in non-alcoholic fatty liver disease. Nutrients 2014, 6, 5679–5703.
9. Araújo, E.P.; Souza, C.T.; Ueno, M.; Cintra, D.E.; Bertolo, M.B.; Carvalheira, J.B.; Saad, M.J.; Velloso, L.A. Infliximab restores glucose homeostasis in an animal model of diet-induced obesity and diabetes. Endocrinology 2007, 148, 5991–5997.
10. Fernandes-lima, F.; Luís, T.; Gomes, R. Short exposure to a high-sucrose diet and the first “hit” of nonalcoholic fatty liver disease in mice. Cells Tissues Organs 2016, 201, 464–472.
11. Masi, L.N.; Rabello, A.; Roque, A.; Mancini, J.; Lira, C.; Curi, R.; Hirabara, S.M. Inflammatory state of periaortic adipose tissue in mice under obesogenic dietary regimens. J. Nutr. Intermed. Metab. 2016, 6, 1–7.
12. West, D.B.; Boozer, C.N.; Moody, D.L.; Atkinson, R.L. Dietary obesity in nine inbred mouse strains. Am. J. Physiol. 1992, 262, R1025–R1032.
13. Reeves, P.G.; Nielsen, F.H.; Fahey, G.C. AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J. Nutr. 1993, 123, 1939–1951.
14. Bligh, E.G.; Dyer, W.J. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 1959, 37, 911–917.
15. Santos, O.O.; Montanher, P.F.; Bonafé, E.G.; Prado, I.N.; Maruyama, S.A.; Matsushita, M.; Visentainer, J.V. A simple, fast and efficient method for transesterification of fatty acids in foods assisted by ultrasound energy. J. Braz. Chem. Soc. 2014, 25, 1712–1719.
16. Saleh, T.S.F.; Calixto, J.B.; Medeiros, Y.S. Effects of anti-inflammatory drugs upon nitrate and myeloperoxidase levels in the mouse pleurisy induced by carrageenan. Peptides 1999, 20, 949–956.
17. Liu, W.; Saint, D. A new quantitative method of real time reverse transcription polymerase chain reaction assay based on simulation of polymerase chain reaction kinetics. Anal. Biochem. 2002, 302, 52–59.
18. Yamada, K.; Mizukoshi, E.; Sunagozaka, H.; Arai, K.; Yamashita, T.; Takeshita, Y.; Misu, H.; Takamura, T.; Kitamura, S.; Zen, Y.; et al. Characteristics of hepatic fatty acid compositions in patients with nonalcoholic steatohepatitis. Liver Int. 2015, 35, 1773.
19. Lambertucci, R.H.; Leandro, C.G.; Vinolo, M.A.; Nachbar, R.T.; Silveira, L.R.; Hirabara, S.M.; Curi, R.; Pithon-Curi, T.C. The effects of palmitic acid on nitric oxide production by rat skeletal muscle: Mechanism via superoxide and iNOS activation. Cell. Physiol. Biochem. 2012, 30, 1169–1180.
20. Hodson, L.; Fielding, B.A. Stearoyl-CoA desaturase: Rogue or innocent bystander? Prog. Lipid Res. 2013, 52, 15–42.
21. Wang, Y.; Viscarra, J.; Kim, S.-J.; Sul, H.S. Transcriptional regulation of hepatic lipogenesis. Nat. Rev. Mol. Cell Biol. 2015, 16, 678–689.
22. Softic, S.; Cohen, D.E.; Kahn, C.R. Role of dietary fructose and hepatic de novo lipogenesis in fatty liver disease. Dig. Dis. Sci. 2016, 61, 1282–1293.
23. Tanaka, N.; Zhang, X.; Sugiyama, E.; Kono, H.; Horiuchi, A.; Nakajima, T.; Kanbe, H.; Tanaka, E.; Gonzalez, F.J.; Aoyama, T. Eicosapentaenoic acid improves hepatic steatosis independent of PPAR alpha SREBP-1. Biochem. Pharmacol. 2010, 80, 1601–1612.
24. Simopoulos, A.P. An Increase in the omega-6/omega-3 fatty acid ratio increases the risk for obesity. Nutrients 2016, 8, 1–17.
25. Schaefer, E.J. Lipoproteins, nutrition, and heart disease. Am. J. Clin. Nutr. 2002, 75, 191–212.
26. Shapiro, H.; Tehilla, M.; Attal-Singer, J.; Bruck, R.; Luzzatti, R.; Singer, P. The therapeutic potential of long-chain omega-3 fatty acids in nonalcoholic fatty liver disease. Clin. Nutr. 2011, 30, 6–19.
27. Wang, Y. Tissue-specific, nutritional, and developmental regulation of rat fatty acid elongases. J. Lipid Res. 2005, 46, 706–715.
28. Jakobsson, A.; Westerberg, R.; Jacobsson, A. Fatty acid elongases in mammals: Their regulation and roles in metabolism. Prog. Lipid Res. 2006, 45, 237–249.
29. Moon, Y.-A.; Ochoa, C.R.; Mitsche, M.A.; Hammer, R.E.; Horton, J.D. Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance. J. Lipid Res. 2014, 55, 2597–2605.
30. Vessby, B.; Gustafsson, I.-B.B.; Tengblad, S.; Berglund, L. Indices of fatty acid desaturase activity in healthy human subjects: Effects of different types of dietary fat. Br. J. Nutr 2013, 110, 1–9.
31. Guillou, H.; Zadravec, D.; Martin, P.G.P.; Jacobsson, A. The key roles of elongases and desaturases in mammalian fatty acid metabolism: Insights from transgenic mice. Prog. Lipid Res. 2010, 49, 186–199.
32. Ntambi, J.M.; Miyazaki, M. Recent insights into stearoyl-CoA desaturase-1. Curr. Opin. Lipidol. 2003, 14, 255–261.
33. Mauvoisin, D.; Mounier, C. Hormonal and nutritional regulation of SCD1 gene expression. Biochimie 2011, 93, 78–86.
34. Sampath, H.; Ntambi, J.M. Polyunsaturated fatty acid regulation of genes of lipid metabolism. Annu. Rev. Nutr. 2005, 25, 317–340.
35. Jiang, G.; Li, Z.; Liu, F.; Ellsworth, K.; Dallas-yang, Q.; Wu, M.; Ronan, J.; Esau, C.; Murphy, C.; Szalkowski, D.; et al. Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase—1. J. Clin. Investig. 2005, 115, 1030–1038.
36. Warensjo, E.; Sundstrom, J.; Vessby, B.; Cederholm, T.; Risérus, U. Markers of dietary fat quality and fatty acid desaturation as predictors of total and cardiovascular mortality: A population-based prospective study. Am. J. Clin. Nutr. 2008, 88, 203–209.
37. Paillard, F.; Catheline, D.; Le Duff, F.; Bouriel, M.; Deugnier, Y.; Pouchard, M.; Daubert, J.C.; Legrand, P. Plasma palmitoleic acid, a product of stearoyl-coA desaturase activity, is an independent marker of triglyceridemia and abdominal adiposity. Nutr. Metab. Cardiovasc. Dis. 2008, 18, 436–440.
38. Warensjö, E.; Risérus, U.; Vessby, B. Fatty acid composition of serum lipids predicts the development of the metabolic syndrome in men. Diabetologia 2005, 48, 1999–2005.
39. Risérus, U.; Ärnlöv, J.; Berglund, L. Long-term predictors of insulin resistance. Diabetes Care 2007, 30, 2928–2933.
40. Vessby, B.; Gustafsson, I.; Tengblad, S.; Boberg, M.; Andersson, A. Desaturation and elongation of fatty acids and insulin action. Ann. N. Y. Acad. Sci. 2002, 967, 183–195.
41. Calder, P.C. n-3 Polyunsaturated fatty acids, inflammation, and inflammatory diseases. Am. J. Clin. Nutr. 2006, 83, 1505S–1519S.
42. Martin, S.A.; Brash, A.R.; Murphy, R.C. The discovery and early structural studies of arachidonic Acid. J. Lipid Res. 2016, 1, 2–3.
43. Galland, L. Diet and inflammation. Nutr. Clin. Pract. 2010, 25, 634–640.
44. Zhao, G.; Etherton, T.D.; Martin, K.R.; Vanden Heuvel, J.P.; Gillies, P.J.; West, S.G.; Kris-Etherton, P.M. Anti-inflammatory effects of polyunsaturated fatty acids in THP-1 cells. Biochem. Biophys. Res. Commun. 2005, 336, 909–917.
45. Li, H.; Ruan, X.Z.; Powis, S.H.; Fernando, R.; Mon, W.Y.; Wheeler, D.C.; Moorhead, J.F.; Varghese, Z. EPA and DHA reduce LPS-induced inflammation responses in HK-2 cells: Evidence for a PPAR-gamma-dependent mechanism. Kidney Int. 2005, 67, 867–874.
46. Ajuwon, K.M.; Spurlock, M.E. Palmitate activates the NF-kappa B transcription factor and induces IL-6 and TNF alpha expression in 3T3-L1 adipocytes. J. Nutr. 2005, 135, 1841–1846.
47. Winterbourn, C.C.; Kettle, A.J. Biomarkers of myeloperoxidase-derived hypochlorous acid. Free Radic. Biol. Med. 2000, 29, 403–409.
48. Chen, T.; Zamora, R.; Zuckerbraun, B.; Billiar, T.R. Role of nitric oxide in liver injury. Curr. Mol. Med. 2003, 3, 519–526.
49. Lima, T.M.; Lima, L.S.; Scavone, C.; Curi, R. Fatty acid control of nitric oxide production by macrophages. FEBS Lett. 2006, 580, 3287–3295.
50. Cacicedo, J.M.; Benjachareowong, S.; Chou, E.; Ruderman, N.B.; Ido, Y. Palmitate-induced apoptosis in cultured bovine retinal pericytes: Roles of NAD (P) H oxidase, oxidant stress, and ceramide. Diabetes 2005, 54, 1838–1845.
51. Lin, H.-H.; Faunce, D.E.; Stacey, M.; Terajewicz, A.; Nakamura, T.; Zhang-Hoover, J.; Kerley, M.; Mucenski, M.L.; Gordon, S.; Stein-Streilein, J. The macrophage F4/80 receptor is required for the induction of antigen-specific efferent regulatory t cells in peripheral tolerance. J. Exp. Med. 2005, 201, 1615–1625.
52. Ceriello, A. Postprandial hyperglycemia and diabetes complications: Is it time to treat? Diabetes 2005, 54, 1–7.