-
1
-
-
0010426032
-
Purification and properties of rat liver microsomal stearyl coenzyme A desaturase
-
P. Strittmatter, L. Spatz, D. Corcoran, M.J. Rogers, B. Setlow, and R. Redline Purification and properties of rat liver microsomal stearyl coenzyme A desaturase Proc. Natl. Acad. Sci. U S A 71 1974 4565 4569
-
(1974)
Proc. Natl. Acad. Sci. U S A
, vol.71
, pp. 4565-4569
-
-
Strittmatter, P.1
Spatz, L.2
Corcoran, D.3
Rogers, M.J.4
Setlow, B.5
Redline, R.6
-
2
-
-
0017181438
-
Mechanism of rat liver microsomal stearyl-CoA desaturase. Studies of the substrate specificity, enzyme-substrate interactions, and the function of lipid
-
H.G. Enoch, A. Catala, and P. Strittmatter Mechanism of rat liver microsomal stearyl-CoA desaturase. Studies of the substrate specificity, enzyme-substrate interactions, and the function of lipid J. Biol. Chem. 251 1976 5095 5103
-
(1976)
J. Biol. Chem.
, vol.251
, pp. 5095-5103
-
-
Enoch, H.G.1
Catala, A.2
Strittmatter, P.3
-
3
-
-
43249127067
-
Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism
-
M.T. Flowers, and J.M. Ntambi Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism Curr. Opin. Lipidol. 19 2008 248 256
-
(2008)
Curr. Opin. Lipidol.
, vol.19
, pp. 248-256
-
-
Flowers, M.T.1
Ntambi, J.M.2
-
4
-
-
33847059562
-
Obesity - A perspective based on the biochemical interrelationship of lipids and carbohydrates
-
R. Jeffcoat Obesity - a perspective based on the biochemical interrelationship of lipids and carbohydrates Med. Hypotheses 68 2007 1159 1171
-
(2007)
Med. Hypotheses
, vol.68
, pp. 1159-1171
-
-
Jeffcoat, R.1
-
5
-
-
0025959304
-
Manipulation of body fat composition with sterculic acid can inhibit mammary carcinomas in vivo
-
D.E. Khoo, B. Fermor, J. Miller, C.B. Wood, K. Apostolov, W. Barker, R.C. Williamson, and N.A. Habib Manipulation of body fat composition with sterculic acid can inhibit mammary carcinomas in vivo Br. J. Cancer 63 1991 97 101
-
(1991)
Br. J. Cancer
, vol.63
, pp. 97-101
-
-
Khoo, D.E.1
Fermor, B.2
Miller, J.3
Wood, C.B.4
Apostolov, K.5
Barker, W.6
Williamson, R.C.7
Habib, N.A.8
-
6
-
-
0028246883
-
Partial characterization of a cDNA for human stearoyl-CoA desaturase and changes in its mRNA expression in some normal and malignant tissues
-
J. Li, S.F. Ding, N.A. Habib, B.F. Fermor, C.B. Wood, and R.S. Gilmour Partial characterization of a cDNA for human stearoyl-CoA desaturase and changes in its mRNA expression in some normal and malignant tissues Int. J. Cancer 57 1994 348 352
-
(1994)
Int. J. Cancer
, vol.57
, pp. 348-352
-
-
Li, J.1
Ding, S.F.2
Habib, N.A.3
Fermor, B.F.4
Wood, C.B.5
Gilmour, R.S.6
-
7
-
-
33745212477
-
Probing the role of stearoyl-CoA desaturase-1 in hepatic insulin resistance
-
M.T. Flowers, M. Miyazaki, X. Liu, and J.M. Ntambi Probing the role of stearoyl-CoA desaturase-1 in hepatic insulin resistance J. Clin. Invest. 116 2006 1478 1481
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1478-1481
-
-
Flowers, M.T.1
Miyazaki, M.2
Liu, X.3
Ntambi, J.M.4
-
8
-
-
33745212925
-
Critical role of stearoyl-CoA desaturase-1 (SCD1) in the onset of diet-induced hepatic insulin resistance
-
R. Gutierrez-Juarez, A. Pocai, C. Mulas, H. Ono, S. Bhanot, B.P. Monia, and L. Rossetti Critical role of stearoyl-CoA desaturase-1 (SCD1) in the onset of diet-induced hepatic insulin resistance J. Clin. Invest. 116 2006 1686 1695
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1686-1695
-
-
Gutierrez-Juarez, R.1
Pocai, A.2
Mulas, C.3
Ono, H.4
Bhanot, S.5
Monia, B.P.6
Rossetti, L.7
-
9
-
-
38049169032
-
Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice
-
M.L. MacDonald, R.R. Singaraja, N. Bissada, P. Ruddle, R. Watts, J.M. Karasinska, W.T. Gibson, C. Fievet, J.E. Vance, B. Staels, and M.R. Hayden Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice J. Lipid Res. 49 2008 217 229
-
(2008)
J. Lipid Res.
, vol.49
, pp. 217-229
-
-
MacDonald, M.L.1
Singaraja, R.R.2
Bissada, N.3
Ruddle, P.4
Watts, R.5
Karasinska, J.M.6
Gibson, W.T.7
Fievet, C.8
Vance, J.E.9
Staels, B.10
Hayden, M.R.11
-
10
-
-
61549135741
-
Despite antiatherogenic metabolic characteristics, SCD1-deficient mice have increased inflammation and atherosclerosis
-
M.L. MacDonald, M. van Eck, R.B. Hildebrand, B.W. Wong, N. Bissada, P. Ruddle, A. Kontush, H. Hussein, M.A. Pouladi, M.J. Chapman, C. Fievet, T.J. van Berkel, B. Staels, B.M. McManus, and M.R. Hayden Despite antiatherogenic metabolic characteristics, SCD1-deficient mice have increased inflammation and atherosclerosis Arterioscler Thromb. Vasc. Biol. 29 2009 341 347
-
(2009)
Arterioscler Thromb. Vasc. Biol.
, vol.29
, pp. 341-347
-
-
MacDonald, M.L.1
Van Eck, M.2
Hildebrand, R.B.3
Wong, B.W.4
Bissada, N.5
Ruddle, P.6
Kontush, A.7
Hussein, H.8
Pouladi, M.A.9
Chapman, M.J.10
Fievet, C.11
Van Berkel, T.J.12
Staels, B.13
McManus, B.M.14
Hayden, M.R.15
-
11
-
-
0032871502
-
Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol
-
J.M. Ntambi Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol J. Lipid Res. 40 1999 1549 1558
-
(1999)
J. Lipid Res.
, vol.40
, pp. 1549-1558
-
-
Ntambi, J.M.1
-
12
-
-
0031773193
-
Degradation of stearoyl-coenzyme A desaturase: Endoproteolytic cleavage by an integral membrane protease
-
F.S. Heinemann, and J. Ozols Degradation of stearoyl-coenzyme A desaturase: endoproteolytic cleavage by an integral membrane protease Mol. Biol. Cell 9 1998 3445 3453 (Pubitemid 28551040)
-
(1998)
Molecular Biology of the Cell
, vol.9
, Issue.12
, pp. 3445-3453
-
-
Heinemann, F.S.1
Ozols, J.2
-
13
-
-
0034254990
-
The N terminus of microsomal delta 9 stearoyl-CoA desaturase contains the sequence determinant for its rapid degradation
-
H. Mziaut, G. Korza, and J. Ozols The N terminus of microsomal delta 9 stearoyl-CoA desaturase contains the sequence determinant for its rapid degradation Proc. Natl. Acad. Sci. U S A 97 2000 8883 8888
-
(2000)
Proc. Natl. Acad. Sci. U S A
, vol.97
, pp. 8883-8888
-
-
Mziaut, H.1
Korza, G.2
Ozols, J.3
-
14
-
-
33745496962
-
Ubiquitin-proteasome-dependent degradation of mammalian ER stearoyl-CoA desaturase
-
H. Kato, K. Sakaki, and K. Mihara Ubiquitin-proteasome-dependent degradation of mammalian ER stearoyl-CoA desaturase J. Cell Sci. 119 2006 2342 2353
-
(2006)
J. Cell Sci.
, vol.119
, pp. 2342-2353
-
-
Kato, H.1
Sakaki, K.2
Mihara, K.3
-
15
-
-
0024297268
-
Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase
-
J.M. Ntambi, S.A. Buhrow, K.H. Kaestner, R.J. Christy, E. Sibley, T.J. Kelly Jr., and M.D. Lane Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase J. Biol. Chem. 263 1988 17291 17300
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 17291-17300
-
-
Ntambi, J.M.1
Buhrow, S.A.2
Kaestner, K.H.3
Christy, R.J.4
Sibley, E.5
Kelly Jr., T.J.6
Lane, M.D.7
-
16
-
-
0024427057
-
Differentiation-induced gene expression in 3T3-L1 preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase
-
K.H. Kaestner, J.M. Ntambi, T.J. Kelly Jr., and M.D. Lane Differentiation-induced gene expression in 3T3-L1 preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase J. Biol. Chem. 264 1989 14755 14761
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 14755-14761
-
-
Kaestner, K.H.1
Ntambi, J.M.2
Kelly Jr., T.J.3
Lane, M.D.4
-
17
-
-
0035862555
-
Scd3-a novel gene of the stearoyl-CoA desaturase family with restricted expression in skin
-
Y. Zheng, S.M. Prouty, A. Harmon, J.P. Sundberg, K.S. Stenn, and S. Parimoo Scd3-a novel gene of the stearoyl-CoA desaturase family with restricted expression in skin Genomics 71 2001 182 191
-
(2001)
Genomics
, vol.71
, pp. 182-191
-
-
Zheng, Y.1
Prouty, S.M.2
Harmon, A.3
Sundberg, J.P.4
Stenn, K.S.5
Parimoo, S.6
-
18
-
-
0141780830
-
Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors
-
M. Miyazaki, M.J. Jacobson, W.C. Man, P. Cohen, E. Asilmaz, J.M. Friedman, and J.M. Ntambi Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors J. Biol. Chem. 278 2003 33904 33911
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33904-33911
-
-
Miyazaki, M.1
Jacobson, M.J.2
Man, W.C.3
Cohen, P.4
Asilmaz, E.5
Friedman, J.M.6
Ntambi, J.M.7
-
19
-
-
0025676462
-
Structure and regulation of rat liver microsomal stearoyl-CoA desaturase gene
-
K. Mihara Structure and regulation of rat liver microsomal stearoyl-CoA desaturase gene J. Biochem. 108 1990 1022 1029
-
(1990)
J. Biochem.
, vol.108
, pp. 1022-1029
-
-
Mihara, K.1
-
20
-
-
0033563109
-
Human stearoyl-CoA desaturase: Alternative transcripts generated from a single gene by usage of tandem polyadenylation sites
-
L. Zhang, L. Ge, S. Parimoo, K. Stenn, and S.M. Prouty Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites Biochem. J. 340 Pt 1 1999 255 264
-
(1999)
Biochem. J.
, vol.340
, Issue.PART 1
, pp. 255-264
-
-
Zhang, L.1
Ge, L.2
Parimoo, S.3
Stenn, K.4
Prouty, S.M.5
-
21
-
-
19744365544
-
Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primates
-
J. Wang, L. Yu, R.E. Schmidt, C. Su, X. Huang, K. Gould, and G. Cao Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primates Biochem. Biophys. Res. Commun. 332 2005 735 742
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.332
, pp. 735-742
-
-
Wang, J.1
Yu, L.2
Schmidt, R.E.3
Su, C.4
Huang, X.5
Gould, K.6
Cao, G.7
-
22
-
-
0033567138
-
Hormonal regulation of stearoyl coenzyme-A desaturase 1 activity and gene expression in primary cultures of chicken hepatocytes
-
P. Lefevre, C. Diot, P. Legrand, and M. Douaire Hormonal regulation of stearoyl coenzyme-A desaturase 1 activity and gene expression in primary cultures of chicken hepatocytes Arch. Biochem. Biophys. 368 1999 329 337
-
(1999)
Arch. Biochem. Biophys.
, vol.368
, pp. 329-337
-
-
Lefevre, P.1
Diot, C.2
Legrand, P.3
Douaire, M.4
-
23
-
-
0026032746
-
Isolation and partial characterization of the gene for goose fatty acid synthase
-
K. Kameda, and A.G. Goodridge Isolation and partial characterization of the gene for goose fatty acid synthase J. Biol. Chem. 266 1991 419 426
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 419-426
-
-
Kameda, K.1
Goodridge, A.G.2
-
24
-
-
33947417338
-
The regulation of stearoyl-CoA desaturase gene expression is tissue specific in chickens
-
S. Dridi, M. Taouis, A. Gertler, E. Decuypere, and J. Buyse The regulation of stearoyl-CoA desaturase gene expression is tissue specific in chickens J. Endocrinol. 192 2007 229 236
-
(2007)
J. Endocrinol.
, vol.192
, pp. 229-236
-
-
Dridi, S.1
Taouis, M.2
Gertler, A.3
Decuypere, E.4
Buyse, J.5
-
25
-
-
0029859896
-
Fatty acid-responsive control of mRNA stability. Unsaturated fatty acid-induced degradation of the Saccharomyces OLE1 transcript
-
C.I. Gonzalez, and C.E. Martin Fatty acid-responsive control of mRNA stability. Unsaturated fatty acid-induced degradation of the Saccharomyces OLE1 transcript J. Biol. Chem. 271 1996 25801 25809
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 25801-25809
-
-
Gonzalez, C.I.1
Martin, C.E.2
-
26
-
-
0028089754
-
AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: The functional sequence within AU-rich elements may be UUAUUUA(U/A)(U/A)
-
C.A. Lagnado, C.Y. Brown, and G.J. Goodall AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: the functional sequence within AU-rich elements may be UUAUUUA(U/A)(U/A) Mol. Cell Biol. 14 1994 7984 7995
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 7984-7995
-
-
Lagnado, C.A.1
Brown, C.Y.2
Goodall, G.J.3
-
27
-
-
0040799893
-
Identification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2
-
D.E. Tabor, J.B. Kim, B.M. Spiegelman, and P.A. Edwards Identification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2 J. Biol. Chem. 274 1999 20603 20610
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 20603-20610
-
-
Tabor, D.E.1
Kim, J.B.2
Spiegelman, B.M.3
Edwards, P.A.4
-
28
-
-
0035395797
-
Isolation and characterization of the human stearoyl-CoA desaturase gene promoter: Requirement of a conserved CCAAT cis-element
-
L. Zhang, L. Ge, T. Tran, K. Stenn, and S.M. Prouty Isolation and characterization of the human stearoyl-CoA desaturase gene promoter: requirement of a conserved CCAAT cis-element Biochem. J. 357 2001 183 193
-
(2001)
Biochem. J.
, vol.357
, pp. 183-193
-
-
Zhang, L.1
Ge, L.2
Tran, T.3
Stenn, K.4
Prouty, S.M.5
-
29
-
-
0034815574
-
Effects of polyunsaturated fatty acids and clofibrate on chicken stearoyl-coA desaturase 1 gene expression
-
P. Lefevre, E. Tripon, C. Plumelet, M. Douaire, and C. Diot Effects of polyunsaturated fatty acids and clofibrate on chicken stearoyl-coA desaturase 1 gene expression Biochem. Biophys. Res. Commun. 280 2001 25 31
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.280
, pp. 25-31
-
-
Lefevre, P.1
Tripon, E.2
Plumelet, C.3
Douaire, M.4
Diot, C.5
-
30
-
-
33646064715
-
Characterization and regulation of the bovine stearoyl-CoA desaturase gene promoter
-
A.F. Keating, J.J. Kennelly, and F.Q. Zhao Characterization and regulation of the bovine stearoyl-CoA desaturase gene promoter Biochem. Biophys. Res. Commun. 344 2006 233 240
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.344
, pp. 233-240
-
-
Keating, A.F.1
Kennelly, J.J.2
Zhao, F.Q.3
-
31
-
-
59049098636
-
Stearoyl-CoA desaturase and its relation to high-carbohydrate diets and obesity
-
M.T. Flowers, and J.M. Ntambi Stearoyl-CoA desaturase and its relation to high-carbohydrate diets and obesity Biochim. Biophys. Acta 1791 2009 85 91
-
(2009)
Biochim. Biophys. Acta
, vol.1791
, pp. 85-91
-
-
Flowers, M.T.1
Ntambi, J.M.2
-
32
-
-
0018756491
-
Regulation of rat hepatic stearoyl coenzyme A desaturase. The roles of insulin and carbohydrate
-
M.R. Prasad, and V.C. Joshi Regulation of rat hepatic stearoyl coenzyme A desaturase. The roles of insulin and carbohydrate J. Biol. Chem. 254 1979 997 999
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 997-999
-
-
Prasad, M.R.1
Joshi, V.C.2
-
33
-
-
0028081005
-
Insulin and dietary fructose induce stearoyl-CoA desaturase 1 gene expression of diabetic mice
-
K.M. Waters, and J.M. Ntambi Insulin and dietary fructose induce stearoyl-CoA desaturase 1 gene expression of diabetic mice J. Biol. Chem. 269 1994 27773 27777
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 27773-27777
-
-
Waters, K.M.1
Ntambi, J.M.2
-
34
-
-
0018641345
-
Hormonal regulation of the terminal enzyme of microsomal stearoyl coenzyme A desaturase in cultured avian liver explants. Role of insulin
-
V.C. Joshi, and L.P. Aranda Hormonal regulation of the terminal enzyme of microsomal stearoyl coenzyme A desaturase in cultured avian liver explants. Role of insulin J. Biol. Chem. 254 1979 11779 11782
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 11779-11782
-
-
Joshi, V.C.1
Aranda, L.P.2
-
35
-
-
0020629904
-
Induction of microsomal stearoyl-CoA desaturation by the administration of various peroxisome proliferators
-
Y. Kawashima, N. Hanioka, M. Matsumura, and H. Kozuka Induction of microsomal stearoyl-CoA desaturation by the administration of various peroxisome proliferators Biochim. Biophys. Acta 752 1983 259 264
-
(1983)
Biochim. Biophys. Acta
, vol.752
, pp. 259-264
-
-
Kawashima, Y.1
Hanioka, N.2
Matsumura, M.3
Kozuka, H.4
-
36
-
-
0019965819
-
Further characterization of a Chinese hamster ovary cell mutant requiring cholesterol and unsaturated fatty acid for growth
-
J. Chin, and T.Y. Chang Further characterization of a Chinese hamster ovary cell mutant requiring cholesterol and unsaturated fatty acid for growth Biochemistry 2 1982 3196 3202
-
(1982)
Biochemistry
, vol.2
, pp. 3196-3202
-
-
Chin, J.1
Chang, T.Y.2
-
37
-
-
0031589158
-
Localization of a negative thyroid hormone-response region in hepatic stearoyl-CoA desaturase gene 1
-
K.M. Waters, C.W. Miller, and J.M. Ntambi Localization of a negative thyroid hormone-response region in hepatic stearoyl-CoA desaturase gene 1 Biochem. Biophys. Res. Commun. 233 1997 838 843
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.233
, pp. 838-843
-
-
Waters, K.M.1
Miller, C.W.2
Ntambi, J.M.3
-
38
-
-
36348951552
-
Tissue-specific effects of central leptin on the expression of genes involved in lipid metabolism in liver and white adipose tissue
-
N. Gallardo, E. Bonzon-Kulichenko, T. Fernandez-Agullo, E. Molto, S. Gomez-Alonso, P. Blanco, J.M. Carrascosa, M. Ros, and A. Andres Tissue-specific effects of central leptin on the expression of genes involved in lipid metabolism in liver and white adipose tissue Endocrinology 148 2007 5604 5610
-
(2007)
Endocrinology
, vol.148
, pp. 5604-5610
-
-
Gallardo, N.1
Bonzon-Kulichenko, E.2
Fernandez-Agullo, T.3
Molto, E.4
Gomez-Alonso, S.5
Blanco, P.6
Carrascosa, J.M.7
Ros, M.8
Andres, A.9
-
39
-
-
77249131862
-
Key role of the ERK1/2 MAPK pathway in the transcriptional regulation of the Stearoyl-CoA Desaturase (SCD1) gene expression in response to leptin
-
D. Mauvoisin, M. Prevost, S. Ducheix, M.P. Arnaud, and C. Mounier Key role of the ERK1/2 MAPK pathway in the transcriptional regulation of the Stearoyl-CoA Desaturase (SCD1) gene expression in response to leptin Mol. Cell Endocrinol. 319 2010 116 128
-
(2010)
Mol. Cell Endocrinol.
, vol.319
, pp. 116-128
-
-
Mauvoisin, D.1
Prevost, M.2
Ducheix, S.3
Arnaud, M.P.4
Mounier, C.5
-
40
-
-
23944435868
-
Polyunsaturated fatty acid regulation of genes of lipid metabolism
-
H. Sampath, and J.M. Ntambi Polyunsaturated fatty acid regulation of genes of lipid metabolism Annu. Rev. Nutr. 25 2005 317 340
-
(2005)
Annu. Rev. Nutr.
, vol.25
, pp. 317-340
-
-
Sampath, H.1
Ntambi, J.M.2
-
41
-
-
56049110515
-
Mechanisms of antidiabetogenic and body weight-lowering effects of estrogen in high-fat diet-fed mice
-
G. Bryzgalova, L. Lundholm, N. Portwood, J.A. Gustafsson, A. Khan, S. Efendic, and K. Dahlman-Wright Mechanisms of antidiabetogenic and body weight-lowering effects of estrogen in high-fat diet-fed mice Am. J. Physiol. Endocrinol. Metab. 295 2008 E904 E912
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.295
-
-
Bryzgalova, G.1
Lundholm, L.2
Portwood, N.3
Gustafsson, J.A.4
Khan, A.5
Efendic, S.6
Dahlman-Wright, K.7
-
42
-
-
14844324489
-
Loss of stearoyl-CoA desaturase expression is a frequent event in prostate carcinoma
-
S. Moore, B. Knudsen, L.D. True, S. Hawley, R. Etzioni, C. Wade, D. Gifford, I. Coleman, and P.S. Nelson Loss of stearoyl-CoA desaturase expression is a frequent event in prostate carcinoma Int. J. Cancer 114 2005 563 571
-
(2005)
Int. J. Cancer
, vol.114
, pp. 563-571
-
-
Moore, S.1
Knudsen, B.2
True, L.D.3
Hawley, S.4
Etzioni, R.5
Wade, C.6
Gifford, D.7
Coleman, I.8
Nelson, P.S.9
-
43
-
-
34249285532
-
Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen
-
S.E. Morgan-Lappe, L.A. Tucker, X. Huang, Q. Zhang, A.V. Sarthy, D. Zakula, L. Vernetti, M. Schurdak, J. Wang, and S.W. Fesik Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen Cancer Res. 67 2007 4390 4398
-
(2007)
Cancer Res.
, vol.67
, pp. 4390-4398
-
-
Morgan-Lappe, S.E.1
Tucker, L.A.2
Huang, X.3
Zhang, Q.4
Sarthy, A.V.5
Zakula, D.6
Vernetti, L.7
Schurdak, M.8
Wang, J.9
Fesik, S.W.10
-
44
-
-
13644263225
-
High stearoyl-CoA desaturase protein and activity levels in simian virus 40 transformed-human lung fibroblasts
-
N. Scaglia, J.M. Caviglia, and R.A. Igal High stearoyl-CoA desaturase protein and activity levels in simian virus 40 transformed-human lung fibroblasts Biochim. Biophys. Acta 1687 2005 141 151
-
(2005)
Biochim. Biophys. Acta
, vol.1687
, pp. 141-151
-
-
Scaglia, N.1
Caviglia, J.M.2
Igal, R.A.3
-
45
-
-
69449099939
-
Inhibition of stearoylCoA desaturase-1 inactivates acetyl-CoA carboxylase and impairs proliferation in cancer cells: Role of AMPK
-
N. Scaglia, J.W. Chisholm, and R.A. Igal Inhibition of stearoylCoA desaturase-1 inactivates acetyl-CoA carboxylase and impairs proliferation in cancer cells: role of AMPK PLoS One 4 2009 e6812
-
(2009)
PLoS One
, vol.4
, pp. 6812
-
-
Scaglia, N.1
Chisholm, J.W.2
Igal, R.A.3
-
46
-
-
54049084951
-
Inhibition of Stearoyl-CoA Desaturase 1 expression in human lung adenocarcinoma cells impairs tumorigenesis
-
N. Scaglia, and R.A. Igal Inhibition of Stearoyl-CoA Desaturase 1 expression in human lung adenocarcinoma cells impairs tumorigenesis Int. J. Oncol. 33 2008 839 850
-
(2008)
Int. J. Oncol.
, vol.33
, pp. 839-850
-
-
Scaglia, N.1
Igal, R.A.2
-
47
-
-
77953471622
-
Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice
-
V. Fritz, Z. Benfodda, G. Rodier, C. Henriquet, F. Iborra, C. Avances, Y. Allory, A. de la Taille, S. Culine, H. Blancou, J.P. Cristol, F. Michel, C. Sardet, and L. Fajas Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice Mol. Cancer Ther. 9 2010 1740 1754
-
(2010)
Mol. Cancer Ther.
, vol.9
, pp. 1740-1754
-
-
Fritz, V.1
Benfodda, Z.2
Rodier, G.3
Henriquet, C.4
Iborra, F.5
Avances, C.6
Allory, Y.7
De La Taille, A.8
Culine, S.9
Blancou, H.10
Cristol, J.P.11
Michel, F.12
Sardet, C.13
Fajas, L.14
-
48
-
-
0016693943
-
Desaturation of stearic acid by liver and adipose tissue from obese-hyperglycaemic mice (ob/ob)
-
M. Enser Desaturation of stearic acid by liver and adipose tissue from obese-hyperglycaemic mice (ob/ob) Biochem. J. 148 1975 551 555
-
(1975)
Biochem. J.
, vol.148
, pp. 551-555
-
-
Enser, M.1
-
49
-
-
60849136007
-
Stearoyl-CoA desaturase-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice
-
M. Miyazaki, H. Sampath, X. Liu, M.T. Flowers, K. Chu, A. Dobrzyn, and J.M. Ntambi Stearoyl-CoA desaturase-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice Biochem. Biophys. Res. Commun. 380 2009 818 822
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.380
, pp. 818-822
-
-
Miyazaki, M.1
Sampath, H.2
Liu, X.3
Flowers, M.T.4
Chu, K.5
Dobrzyn, A.6
Ntambi, J.M.7
-
50
-
-
0037143752
-
Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity
-
J.M. Ntambi, M. Miyazaki, J.P. Stoehr, H. Lan, C.M. Kendziorski, B.S. Yandell, Y. Song, P. Cohen, J.M. Friedman, and A.D. Attie Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity Proc. Natl. Acad. Sci. U S A 99 2002 11482 11486
-
(2002)
Proc. Natl. Acad. Sci. U S A
, vol.99
, pp. 11482-11486
-
-
Ntambi, J.M.1
Miyazaki, M.2
Stoehr, J.P.3
Lan, H.4
Kendziorski, C.M.5
Yandell, B.S.6
Song, Y.7
Cohen, P.8
Friedman, J.M.9
Attie, A.D.10
-
51
-
-
33644821916
-
Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans
-
M.W. Hulver, J.R. Berggren, M.J. Carper, M. Miyazaki, J.M. Ntambi, E.P. Hoffman, J.P. Thyfault, R. Stevens, G.L. Dohm, J.A. Houmard, and D.M. Muoio Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans Cell Metab. 2 2005 251 261
-
(2005)
Cell Metab.
, vol.2
, pp. 251-261
-
-
Hulver, M.W.1
Berggren, J.R.2
Carper, M.J.3
Miyazaki, M.4
Ntambi, J.M.5
Hoffman, E.P.6
Thyfault, J.P.7
Stevens, R.8
Dohm, G.L.9
Houmard, J.A.10
Muoio, D.M.11
-
52
-
-
20144388684
-
Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase-1
-
G. Jiang, Z. Li, F. Liu, K. Ellsworth, Q. Dallas-Yang, M. Wu, J. Ronan, C. Esau, C. Murphy, D. Szalkowski, R. Bergeron, T. Doebber, and B.B. Zhang Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase-1 J. Clin. Invest. 115 2005 1030 1038
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1030-1038
-
-
Jiang, G.1
Li, Z.2
Liu, F.3
Ellsworth, K.4
Dallas-Yang, Q.5
Wu, M.6
Ronan, J.7
Esau, C.8
Murphy, C.9
Szalkowski, D.10
Bergeron, R.11
Doebber, T.12
Zhang, B.B.13
-
53
-
-
34047269605
-
Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat
-
H. Sampath, M. Miyazaki, A. Dobrzyn, and J.M. Ntambi Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat J. Biol. Chem. 282 2007 2483 2493
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 2483-2493
-
-
Sampath, H.1
Miyazaki, M.2
Dobrzyn, A.3
Ntambi, J.M.4
-
54
-
-
41149102818
-
Low hepatic stearoyl-CoA desaturase 1 activity is associated with fatty liver and insulin resistance in obese humans
-
N. Stefan, A. Peter, A. Cegan, H. Staiger, J. Machann, F. Schick, C.D. Claussen, A. Fritsche, H.U. Haring, and E. Schleicher Low hepatic stearoyl-CoA desaturase 1 activity is associated with fatty liver and insulin resistance in obese humans Diabetologia 51 2008 648 656
-
(2008)
Diabetologia
, vol.51
, pp. 648-656
-
-
Stefan, N.1
Peter, A.2
Cegan, A.3
Staiger, H.4
MacHann, J.5
Schick, F.6
Claussen, C.D.7
Fritsche, A.8
Haring, H.U.9
Schleicher, E.10
-
55
-
-
20944444283
-
Rosiglitazone increases indexes of stearoyl-CoA desaturase activity in humans: Link to insulin sensitization and the role of dominant-negative mutation in peroxisome proliferator-activated receptor-gamma
-
U. Riserus, G.D. Tan, B.A. Fielding, M.J. Neville, J. Currie, D.B. Savage, V.K. Chatterjee, K.N. Frayn, S. O'Rahilly, and F. Karpe Rosiglitazone increases indexes of stearoyl-CoA desaturase activity in humans: link to insulin sensitization and the role of dominant-negative mutation in peroxisome proliferator-activated receptor-gamma Diabetes 54 2005 1379 1384
-
(2005)
Diabetes
, vol.54
, pp. 1379-1384
-
-
Riserus, U.1
Tan, G.D.2
Fielding, B.A.3
Neville, M.J.4
Currie, J.5
Savage, D.B.6
Chatterjee, V.K.7
Frayn, K.N.8
O'Rahilly, S.9
Karpe, F.10
-
56
-
-
0029992478
-
A model cell line to study regulation of stearoyl-CoA desaturase gene 1 expression by insulin and polyunsaturated fatty acids
-
J.M. Ntambi, A.M. Sessler, and T. Takova A model cell line to study regulation of stearoyl-CoA desaturase gene 1 expression by insulin and polyunsaturated fatty acids Biochem. Biophys. Res. Commun. 220 1996 990 995
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.220
, pp. 990-995
-
-
Ntambi, J.M.1
Sessler, A.M.2
Takova, T.3
-
57
-
-
66249090283
-
Role of the PI3-kinase/mTor pathway in the regulation of the stearoyl CoA desaturase (SCD1) gene expression by insulin in liver
-
D. Mauvoisin, G. Rocque, O. Arfa, A. Radenne, P. Boissier, and C. Mounier Role of the PI3-kinase/mTor pathway in the regulation of the stearoyl CoA desaturase (SCD1) gene expression by insulin in liver J. Cell Commun. Signal. 1 2007 113 125
-
(2007)
J. Cell Commun. Signal.
, vol.1
, pp. 113-125
-
-
Mauvoisin, D.1
Rocque, G.2
Arfa, O.3
Radenne, A.4
Boissier, P.5
Mounier, C.6
-
58
-
-
0034815771
-
Cloning and characterization of the human stearoyl-CoA desaturase gene promoter: Transcriptional activation by sterol regulatory element binding protein and repression by polyunsaturated fatty acids and cholesterol
-
H. Bene, D. Lasky, and J.M. Ntambi Cloning and characterization of the human stearoyl-CoA desaturase gene promoter: transcriptional activation by sterol regulatory element binding protein and repression by polyunsaturated fatty acids and cholesterol Biochem. Biophys. Res. Commun. 284 2001 1194 1198
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.284
, pp. 1194-1198
-
-
Bene, H.1
Lasky, D.2
Ntambi, J.M.3
-
59
-
-
0021846981
-
Evidence for an increase in transcription of specific mRNAs during differentiation of 3T3-L1 preadipocytes
-
D.A. Bernlohr, M.A. Bolanowski, T.J. Kelly Jr., and M.D. Lane Evidence for an increase in transcription of specific mRNAs during differentiation of 3T3-L1 preadipocytes J. Biol. Chem. 260 1985 5563 5567
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 5563-5567
-
-
Bernlohr, D.A.1
Bolanowski, M.A.2
Kelly Jr., T.J.3
Lane, M.D.4
-
60
-
-
23744496757
-
Adipose development: From stem cell to adipocyte
-
T.C. Otto, and M.D. Lane Adipose development: from stem cell to adipocyte Crit. Rev. Biochem. Mol. Biol. 40 2005 229 242
-
(2005)
Crit. Rev. Biochem. Mol. Biol.
, vol.40
, pp. 229-242
-
-
Otto, T.C.1
Lane, M.D.2
-
61
-
-
0029909557
-
CAMP activates the expression of stearoyl-CoA desaturase gene 1 during early preadipocyte differentiation
-
D.A. Casimir, and J.M. Ntambi cAMP activates the expression of stearoyl-CoA desaturase gene 1 during early preadipocyte differentiation J. Biol. Chem. 271 1996 29847 29853
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 29847-29853
-
-
Casimir, D.A.1
Ntambi, J.M.2
-
63
-
-
0026014465
-
Cell-free transcription directed by the 422 adipose P2 gene promoter: Activation by the CCAAT/enhancer binding protein
-
D. Cheneval, R.J. Christy, D. Geiman, P. Cornelius, and M.D. Lane Cell-free transcription directed by the 422 adipose P2 gene promoter: activation by the CCAAT/enhancer binding protein Proc. Natl. Acad. Sci. U S A 88 1991 8465 8469
-
(1991)
Proc. Natl. Acad. Sci. U S A
, vol.88
, pp. 8465-8469
-
-
Cheneval, D.1
Christy, R.J.2
Geiman, D.3
Cornelius, P.4
Lane, M.D.5
-
64
-
-
0024728988
-
Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes
-
R.J. Christy, V.W. Yang, J.M. Ntambi, D.E. Geiman, W.H. Landschulz, A.D. Friedman, Y. Nakabeppu, T.J. Kelly, and M.D. Lane Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes Genes Dev. 3 1989 1323 1335
-
(1989)
Genes Dev.
, vol.3
, pp. 1323-1335
-
-
Christy, R.J.1
Yang, V.W.2
Ntambi, J.M.3
Geiman, D.E.4
Landschulz, W.H.5
Friedman, A.D.6
Nakabeppu, Y.7
Kelly, T.J.8
Lane, M.D.9
-
65
-
-
0032537466
-
Nuclear factor 1 is essential for the expression of stearoyl-CoA desaturase 1 gene during preadipocyte differentiation
-
M.V. Singh, and J.M. Ntambi Nuclear factor 1 is essential for the expression of stearoyl-CoA desaturase 1 gene during preadipocyte differentiation Biochim. Biophys. Acta 1398 1998 148 156
-
(1998)
Biochim. Biophys. Acta
, vol.1398
, pp. 148-156
-
-
Singh, M.V.1
Ntambi, J.M.2
-
66
-
-
33845398283
-
Transcriptional regulation by insulin: From the receptor to the gene
-
C. Mounier, and B.I. Posner Transcriptional regulation by insulin: from the receptor to the gene Can. J. Physiol. Pharmacol. 84 2006 713 724
-
(2006)
Can. J. Physiol. Pharmacol.
, vol.84
, pp. 713-724
-
-
Mounier, C.1
Posner, B.I.2
-
67
-
-
34347406521
-
SREBP-1c transcription factor and lipid homeostasis: Clinical perspective
-
P. Ferre, and F. Foufelle SREBP-1c transcription factor and lipid homeostasis: clinical perspective Horm. Res. 68 2007 72 82
-
(2007)
Horm. Res.
, vol.68
, pp. 72-82
-
-
Ferre, P.1
Foufelle, F.2
-
68
-
-
0032567445
-
Nuclear sterol regulatory element-binding proteins activate genes responsible for the entire program of unsaturated fatty acid biosynthesis in transgenic mouse liver
-
I. Shimomura, H. Shimano, B.S. Korn, Y. Bashmakov, and J.D. Horton Nuclear sterol regulatory element-binding proteins activate genes responsible for the entire program of unsaturated fatty acid biosynthesis in transgenic mouse liver J. Biol. Chem. 273 1998 35299 35306
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 35299-35306
-
-
Shimomura, I.1
Shimano, H.2
Korn, B.S.3
Bashmakov, Y.4
Horton, J.D.5
-
69
-
-
33747034520
-
Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c
-
S.B. Biddinger, M. Miyazaki, J. Boucher, J.M. Ntambi, and C.R. Kahn Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c Diabetes 55 2006 2032 2041
-
(2006)
Diabetes
, vol.55
, pp. 2032-2041
-
-
Biddinger, S.B.1
Miyazaki, M.2
Boucher, J.3
Ntambi, J.M.4
Kahn, C.R.5
-
70
-
-
45449106572
-
Adipose tissue gene expression profiles in ob/ob mice treated with leptin
-
W. Zhang, M.A. Della-Fera, D.L. Hartzell, D. Hausman, and C.A. Baile Adipose tissue gene expression profiles in ob/ob mice treated with leptin Life Sci. 83 2008 35 42
-
(2008)
Life Sci.
, vol.83
, pp. 35-42
-
-
Zhang, W.1
Della-Fera, M.A.2
Hartzell, D.L.3
Hausman, D.4
Baile, C.A.5
-
71
-
-
73949151936
-
Interaction of leptin and amylin in the long-term maintenance of weight loss in diet-induced obese rats
-
J.L. Trevaskis, C. Lei, J.E. Koda, C. Weyer, D.G. Parkes, and J.D. Roth Interaction of leptin and amylin in the long-term maintenance of weight loss in diet-induced obese rats Obes. (Silver Spring) 18 2010 21 26
-
(2010)
Obes. (Silver Spring)
, vol.18
, pp. 21-26
-
-
Trevaskis, J.L.1
Lei, C.2
Koda, J.E.3
Weyer, C.4
Parkes, D.G.5
Roth, J.D.6
-
72
-
-
0034776770
-
Selective deletion of leptin receptor in neurons leads to obesity
-
P. Cohen, C. Zhao, X. Cai, J.M. Montez, S.C. Rohani, P. Feinstein, P. Mombaerts, and J.M. Friedman Selective deletion of leptin receptor in neurons leads to obesity J. Clin. Invest. 108 2001 1113 1121
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1113-1121
-
-
Cohen, P.1
Zhao, C.2
Cai, X.3
Montez, J.M.4
Rohani, S.C.5
Feinstein, P.6
Mombaerts, P.7
Friedman, J.M.8
-
73
-
-
0242331290
-
CNS melanocortin and leptin effects on stearoyl-CoA desaturase-1 and resistin expression
-
J. Lin, Y.H. Choi, D.L. Hartzell, C. Li, M.A. Della-Fera, and C.A. Baile CNS melanocortin and leptin effects on stearoyl-CoA desaturase-1 and resistin expression Biochem. Biophys. Res. Commun. 311 2003 324 328
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.311
, pp. 324-328
-
-
Lin, J.1
Choi, Y.H.2
Hartzell, D.L.3
Li, C.4
Della-Fera, M.A.5
Baile, C.A.6
-
74
-
-
34047250349
-
Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells
-
N.K. Saxena, D. Sharma, X. Ding, S. Lin, F. Marra, D. Merlin, and F.A. Anania Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells Cancer Res. 67 2007 2497 2507
-
(2007)
Cancer Res.
, vol.67
, pp. 2497-2507
-
-
Saxena, N.K.1
Sharma, D.2
Ding, X.3
Lin, S.4
Marra, F.5
Merlin, D.6
Anania, F.A.7
-
75
-
-
0029860791
-
Modulation of insulin activities by leptin
-
B. Cohen, D. Novick, and M. Rubinstein Modulation of insulin activities by leptin Science 274 1996 1185 1188
-
(1996)
Science
, vol.274
, pp. 1185-1188
-
-
Cohen, B.1
Novick, D.2
Rubinstein, M.3
-
76
-
-
30044443872
-
Leptin enhances alpha1(I) collagen gene expression in LX-2 human hepatic stellate cells through JAK-mediated H2O2-dependent MAPK pathways
-
Q. Cao, K.M. Mak, and C.S. Lieber Leptin enhances alpha1(I) collagen gene expression in LX-2 human hepatic stellate cells through JAK-mediated H2O2-dependent MAPK pathways J. Cell Biochem. 97 2006 188 197
-
(2006)
J. Cell Biochem.
, vol.97
, pp. 188-197
-
-
Cao, Q.1
Mak, K.M.2
Lieber, C.S.3
-
77
-
-
1042289785
-
Leptin stimulates tissue inhibitor of metalloproteinase-1 in human hepatic stellate cells: Respective roles of the JAK/STAT and JAK-mediated H2O2-dependant MAPK pathways
-
Q. Cao, K.M. Mak, C. Ren, and C.S. Lieber Leptin stimulates tissue inhibitor of metalloproteinase-1 in human hepatic stellate cells: respective roles of the JAK/STAT and JAK-mediated H2O2-dependant MAPK pathways J. Biol. Chem. 279 2004 4292 4304
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 4292-4304
-
-
Cao, Q.1
Mak, K.M.2
Ren, C.3
Lieber, C.S.4
-
78
-
-
34547933899
-
Defects in the leptin axis reduce abundance of the ABCG5-ABCG8 sterol transporter in liver
-
N.S. Sabeva, E.J. Rouse, and G.A. Graf Defects in the leptin axis reduce abundance of the ABCG5-ABCG8 sterol transporter in liver J. Biol. Chem. 282 2007 22397 22405
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 22397-22405
-
-
Sabeva, N.S.1
Rouse, E.J.2
Graf, G.A.3
-
79
-
-
77949484430
-
Dysregulation of sterol regulatory element binding protein-1c in livers of morbidly obese women is associated with altered suppressor of cytokine signaling-3 and signal transducer and activator of transcription-1 signaling
-
M.B. Elam, C. Yellaturu, G.E. Howell, X. Deng, G.S. Cowan, P. Kumar, E.A. Park, M.L. Hiler, H.G. Wilcox, T.A. Hughes, G.A. Cook, and R. Raghow Dysregulation of sterol regulatory element binding protein-1c in livers of morbidly obese women is associated with altered suppressor of cytokine signaling-3 and signal transducer and activator of transcription-1 signaling Metabolism 59 2010 587 598
-
(2010)
Metabolism
, vol.59
, pp. 587-598
-
-
Elam, M.B.1
Yellaturu, C.2
Howell, G.E.3
Deng, X.4
Cowan, G.S.5
Kumar, P.6
Park, E.A.7
Hiler, M.L.8
Wilcox, H.G.9
Hughes, T.A.10
Cook, G.A.11
Raghow, R.12
-
80
-
-
33744492590
-
Long-term administration of estradiol decreases expression of hepatic lipogenic genes and improves insulin sensitivity in ob/ob mice: A possible mechanism is through direct regulation of signal transducer and activator of transcription 3
-
H. Gao, G. Bryzgalova, E. Hedman, A. Khan, S. Efendic, J.A. Gustafsson, and K. Dahlman-Wright Long-term administration of estradiol decreases expression of hepatic lipogenic genes and improves insulin sensitivity in ob/ob mice: a possible mechanism is through direct regulation of signal transducer and activator of transcription 3 Mol. Endocrinol. 20 2006 1287 1299
-
(2006)
Mol. Endocrinol.
, vol.20
, pp. 1287-1299
-
-
Gao, H.1
Bryzgalova, G.2
Hedman, E.3
Khan, A.4
Efendic, S.5
Gustafsson, J.A.6
Dahlman-Wright, K.7
-
81
-
-
0036838945
-
Interaction between growth hormone and insulin in the regulation of lipoprotein metabolism in the rat
-
F. Frick, D. Linden, C. Ameen, S. Eden, A. Mode, and J. Oscarsson Interaction between growth hormone and insulin in the regulation of lipoprotein metabolism in the rat Am. J. Physiol. Endocrinol. Metab. 283 2002 E1023 E1031
-
(2002)
Am. J. Physiol. Endocrinol. Metab.
, vol.283
-
-
Frick, F.1
Linden, D.2
Ameen, C.3
Eden, S.4
Mode, A.5
Oscarsson, J.6
-
82
-
-
0034133242
-
Influence of bovine growth hormone and growth hormone-releasing factor on messenger RNA abundance of lipoprotein lipase and stearoyl-CoA desaturase in the bovine mammary gland and adipose tissue
-
N.S. Beswick, and J.J. Kennelly Influence of bovine growth hormone and growth hormone-releasing factor on messenger RNA abundance of lipoprotein lipase and stearoyl-CoA desaturase in the bovine mammary gland and adipose tissue J. Anim. Sci. 78 2000 412 419
-
(2000)
J. Anim. Sci.
, vol.78
, pp. 412-419
-
-
Beswick, N.S.1
Kennelly, J.J.2
-
83
-
-
85047690323
-
Keratinocyte growth factor and the transcription factors C/EBP alpha, C/EBP delta, and SREBP-1c regulate fatty acid synthesis in alveolar type II cells
-
R.J. Mason, T. Pan, K.E. Edeen, L.D. Nielsen, F. Zhang, M. Longphre, M.R. Eckart, and S. Neben Keratinocyte growth factor and the transcription factors C/EBP alpha, C/EBP delta, and SREBP-1c regulate fatty acid synthesis in alveolar type II cells J. Clin. Invest. 112 2003 244 255
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 244-255
-
-
Mason, R.J.1
Pan, T.2
Edeen, K.E.3
Nielsen, L.D.4
Zhang, F.5
Longphre, M.6
Eckart, M.R.7
Neben, S.8
-
84
-
-
4143050198
-
Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins
-
J.B. Demoulin, J. Ericsson, A. Kallin, C. Rorsman, L. Ronnstrand, and C.H. Heldin Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins J. Biol. Chem. 279 2004 35392 35402
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 35392-35402
-
-
Demoulin, J.B.1
Ericsson, J.2
Kallin, A.3
Rorsman, C.4
Ronnstrand, L.5
Heldin, C.H.6
-
85
-
-
30844448578
-
KGF induces lipogenic genes through a PI3K and JNK/SREBP-1 pathway in H292 cells
-
Y. Chang, J. Wang, X. Lu, D.P. Thewke, and R.J. Mason KGF induces lipogenic genes through a PI3K and JNK/SREBP-1 pathway in H292 cells J. Lipid Res. 46 2005 2624 2635
-
(2005)
J. Lipid Res.
, vol.46
, pp. 2624-2635
-
-
Chang, Y.1
Wang, J.2
Lu, X.3
Thewke, D.P.4
Mason, R.J.5
-
86
-
-
0037016693
-
Transforming growth factor-beta regulates stearoyl coenzyme A desaturase expression through a Smad signaling pathway
-
W. Samuel, C.N. Nagineni, R.K. Kutty, W.T. Parks, J.S. Gordon, S.M. Prouty, J.J. Hooks, and B. Wiggert Transforming growth factor-beta regulates stearoyl coenzyme A desaturase expression through a Smad signaling pathway J. Biol. Chem. 277 2002 59 66
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 59-66
-
-
Samuel, W.1
Nagineni, C.N.2
Kutty, R.K.3
Parks, W.T.4
Gordon, J.S.5
Prouty, S.M.6
Hooks, J.J.7
Wiggert, B.8
-
87
-
-
0028908031
-
Sequence analysis and characterization of FAR-17c, an androgen-dependent gene in the flank organs of hamsters
-
R. Ideta, T. Seki, and K. Adachi Sequence analysis and characterization of FAR-17c, an androgen-dependent gene in the flank organs of hamsters J. Dermatol. Sci. 9 1995 94 102
-
(1995)
J. Dermatol. Sci.
, vol.9
, pp. 94-102
-
-
Ideta, R.1
Seki, T.2
Adachi, K.3
-
88
-
-
0031929902
-
The isolation and characterization of androgen-dependent genes in the flank organs of golden Syrian hamsters
-
R. Ideta, T. Seki, K. Adachi, and Y. Nakayama The isolation and characterization of androgen-dependent genes in the flank organs of golden Syrian hamsters Dermatology 196 1998 47 50
-
(1998)
Dermatology
, vol.196
, pp. 47-50
-
-
Ideta, R.1
Seki, T.2
Adachi, K.3
Nakayama, Y.4
-
89
-
-
0033540056
-
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
-
M. Kojima, H. Hosoda, Y. Date, M. Nakazato, H. Matsuo, and K. Kangawa Ghrelin is a growth-hormone-releasing acylated peptide from stomach Nature 402 1999 656 660
-
(1999)
Nature
, vol.402
, pp. 656-660
-
-
Kojima, M.1
Hosoda, H.2
Date, Y.3
Nakazato, M.4
Matsuo, H.5
Kangawa, K.6
-
90
-
-
78650512069
-
Central leptin versus ghrelin: Effects on bone marrow adiposity and gene expression
-
S. Ambati, Q. Li, S. Rayalam, D.L. Hartzell, M.A. Della-Fera, M.W. Hamrick, and C.A. Baile Central leptin versus ghrelin: effects on bone marrow adiposity and gene expression Endocrine 2009
-
(2009)
Endocrine
-
-
Ambati, S.1
Li, Q.2
Rayalam, S.3
Hartzell, D.L.4
Della-Fera, M.A.5
Hamrick, M.W.6
Baile, C.A.7
-
91
-
-
33244495940
-
Evidence that oestrogen receptor-alpha plays an important role in the regulation of glucose homeostasis in mice: Insulin sensitivity in the liver
-
G. Bryzgalova, H. Gao, B. Ahren, J.R. Zierath, D. Galuska, T.L. Steiler, K. Dahlman-Wright, S. Nilsson, J.A. Gustafsson, S. Efendic, and A. Khan Evidence that oestrogen receptor-alpha plays an important role in the regulation of glucose homeostasis in mice: insulin sensitivity in the liver Diabetologia 49 2006 588 597
-
(2006)
Diabetologia
, vol.49
, pp. 588-597
-
-
Bryzgalova, G.1
Gao, H.2
Ahren, B.3
Zierath, J.R.4
Galuska, D.5
Steiler, T.L.6
Dahlman-Wright, K.7
Nilsson, S.8
Gustafsson, J.A.9
Efendic, S.10
Khan, A.11
-
92
-
-
45849086609
-
Key lipogenic gene expression can be decreased by estrogen in human adipose tissue
-
L. Lundholm, H. Zang, A.L. Hirschberg, J.A. Gustafsson, P. Arner, and K. Dahlman-Wright Key lipogenic gene expression can be decreased by estrogen in human adipose tissue Fertil. Steril. 90 2008 44 48
-
(2008)
Fertil. Steril.
, vol.90
, pp. 44-48
-
-
Lundholm, L.1
Zang, H.2
Hirschberg, A.L.3
Gustafsson, J.A.4
Arner, P.5
Dahlman-Wright, K.6
-
93
-
-
0037197693
-
Molecular differences caused by differentiation of 3T3-L1 preadipocytes in the presence of either dehydroepiandrosterone (DHEA) or 7-oxo-DHEA
-
F.E. Gomez, M. Miyazaki, Y.C. Kim, P. Marwah, H.A. Lardy, J.M. Ntambi, and B.G. Fox Molecular differences caused by differentiation of 3T3-L1 preadipocytes in the presence of either dehydroepiandrosterone (DHEA) or 7-oxo-DHEA Biochemistry 41 2002 5473 5482
-
(2002)
Biochemistry
, vol.41
, pp. 5473-5482
-
-
Gomez, F.E.1
Miyazaki, M.2
Kim, Y.C.3
Marwah, P.4
Lardy, H.A.5
Ntambi, J.M.6
Fox, B.G.7
-
94
-
-
56049111618
-
Hepatic regulation of fatty acid synthase by insulin and T3: Evidence for T3 genomic and nongenomic actions
-
A. Radenne, M. Akpa, C. Martel, S. Sawadogo, D. Mauvoisin, and C. Mounier Hepatic regulation of fatty acid synthase by insulin and T3: evidence for T3 genomic and nongenomic actions Am. J. Physiol. Endocrinol. Metab. 295 2008 E884 E894
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.295
-
-
Radenne, A.1
Akpa, M.2
Martel, C.3
Sawadogo, S.4
Mauvoisin, D.5
Mounier, C.6
-
95
-
-
35148879153
-
Effects of prior or concurrent food restriction on amylin-induced changes in body weight and body composition in high-fat-fed female rats
-
J.D. Roth, H. Hughes, T. Coffey, H. Maier, J.L. Trevaskis, and C.M. Anderson Effects of prior or concurrent food restriction on amylin-induced changes in body weight and body composition in high-fat-fed female rats Am. J. Physiol. Endocrinol. Metab. 293 2007 E1112 E1117
-
(2007)
Am. J. Physiol. Endocrinol. Metab.
, vol.293
-
-
Roth, J.D.1
Hughes, H.2
Coffey, T.3
Maier, H.4
Trevaskis, J.L.5
Anderson, C.M.6
-
96
-
-
0025283305
-
Assembly and secretion of hepatic very-low-density lipoprotein
-
G.F. Gibbons Assembly and secretion of hepatic very-low-density lipoprotein Biochem. J. 268 1990 1 13
-
(1990)
Biochem. J.
, vol.268
, pp. 1-13
-
-
Gibbons, G.F.1
-
97
-
-
67349249102
-
Highly purified eicosapentaenoic acid prevents the progression of hepatic steatosis by repressing monounsaturated fatty acid synthesis in high-fat/high-sucrose diet-fed mice
-
S. Kajikawa, T. Harada, A. Kawashima, K. Imada, and K. Mizuguchi Highly purified eicosapentaenoic acid prevents the progression of hepatic steatosis by repressing monounsaturated fatty acid synthesis in high-fat/high-sucrose diet-fed mice Prostaglandins Leukot. Essent. Fatty Acids 80 2009 229 238
-
(2009)
Prostaglandins Leukot. Essent. Fatty Acids
, vol.80
, pp. 229-238
-
-
Kajikawa, S.1
Harada, T.2
Kawashima, A.3
Imada, K.4
Mizuguchi, K.5
-
98
-
-
3042819785
-
A new hypotensive polyunsaturated fatty acid dietary combination regulates oleic acid accumulation by suppression of stearoyl CoA desaturase 1 gene expression in the SHR model of genetic hypertension
-
J. Bellenger, S. Bellenger, L. Clement, S. Mandard, C. Diot, J.P. Poisson, and M. Narce A new hypotensive polyunsaturated fatty acid dietary combination regulates oleic acid accumulation by suppression of stearoyl CoA desaturase 1 gene expression in the SHR model of genetic hypertension Faseb J. 18 2004 773 775
-
(2004)
Faseb J.
, vol.18
, pp. 773-775
-
-
Bellenger, J.1
Bellenger, S.2
Clement, L.3
Mandard, S.4
Diot, C.5
Poisson, J.P.6
Narce, M.7
-
99
-
-
0032581382
-
Conjugated linoleic acid decreases hepatic stearoyl-CoA desaturase mRNA expression
-
K.N. Lee, M.W. Pariza, and J.M. Ntambi Conjugated linoleic acid decreases hepatic stearoyl-CoA desaturase mRNA expression Biochem. Biophysical Res. Commun. 248 1998 817 821
-
(1998)
Biochem. Biophysical Res. Commun.
, vol.248
, pp. 817-821
-
-
Lee, K.N.1
Pariza, M.W.2
Ntambi, J.M.3
-
100
-
-
0034805403
-
Regulation of stearoyl-CoA desaturase activity by the trans-10, cis-12 isomer of conjugated linoleic acid in HepG2 cells
-
Y. Choi, Y. Park, M.W. Pariza, and J.M. Ntambi Regulation of stearoyl-CoA desaturase activity by the trans-10, cis-12 isomer of conjugated linoleic acid in HepG2 cells Biochem. Biophys. Res. Commun. 284 2001 689 693
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.284
, pp. 689-693
-
-
Choi, Y.1
Park, Y.2
Pariza, M.W.3
Ntambi, J.M.4
-
102
-
-
0029823995
-
Peroxisome proliferators induce mouse liver stearoyl-CoA desaturase 1 gene expression
-
C.W. Miller, and J.M. Ntambi Peroxisome proliferators induce mouse liver stearoyl-CoA desaturase 1 gene expression Proc. Natl. Acad. Sci. U S A 93 1996 9443 9448
-
(1996)
Proc. Natl. Acad. Sci. U S A
, vol.93
, pp. 9443-9448
-
-
Miller, C.W.1
Ntambi, J.M.2
-
103
-
-
0032796505
-
Conjugated linoleic acid is a potent naturally occurring ligand and activator of PPARalpha
-
S.Y. Moya-Camarena, J.P. Vanden Heuvel, S.G. Blanchard, L.A. Leesnitzer, and M.A. Belury Conjugated linoleic acid is a potent naturally occurring ligand and activator of PPARalpha J. Lipid Res. 40 1999 1426 1433
-
(1999)
J. Lipid Res.
, vol.40
, pp. 1426-1433
-
-
Moya-Camarena, S.Y.1
Vanden Heuvel, J.P.2
Blanchard, S.G.3
Leesnitzer, L.A.4
Belury, M.A.5
-
104
-
-
0036617627
-
Eicosapentaenoic acid induces mRNA expression of peroxisome proliferator-activated receptor gamma
-
C. Chambrier, J.P. Bastard, J. Rieusset, E. Chevillotte, D. Bonnefont-Rousselot, P. Therond, B. Hainque, J.P. Riou, M. Laville, and H. Vidal Eicosapentaenoic acid induces mRNA expression of peroxisome proliferator-activated receptor gamma Obes. Res. 10 2002 518 525
-
(2002)
Obes. Res.
, vol.10
, pp. 518-525
-
-
Chambrier, C.1
Bastard, J.P.2
Rieusset, J.3
Chevillotte, E.4
Bonnefont-Rousselot, D.5
Therond, P.6
Hainque, B.7
Riou, J.P.8
Laville, M.9
Vidal, H.10
-
105
-
-
0141739735
-
Isomer-specific regulation of metabolism and PPARgamma signaling by CLA in human preadipocytes
-
J.M. Brown, M.S. Boysen, S.S. Jensen, R.F. Morrison, J. Storkson, R. Lea-Currie, M. Pariza, S. Mandrup, and M.K. McIntosh Isomer-specific regulation of metabolism and PPARgamma signaling by CLA in human preadipocytes J. Lipid Res. 44 2003 1287 1300
-
(2003)
J. Lipid Res.
, vol.44
, pp. 1287-1300
-
-
Brown, J.M.1
Boysen, M.S.2
Jensen, S.S.3
Morrison, R.F.4
Storkson, J.5
Lea-Currie, R.6
Pariza, M.7
Mandrup, S.8
McIntosh, M.K.9
-
106
-
-
43249114663
-
N-3 polyunsaturated fatty acid regulation of hepatic gene transcription
-
D.B. Jump N-3 polyunsaturated fatty acid regulation of hepatic gene transcription Curr. Opin. Lipidol. 19 2008 242 247
-
(2008)
Curr. Opin. Lipidol.
, vol.19
, pp. 242-247
-
-
Jump, D.B.1
-
107
-
-
0035932990
-
Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR
-
J. Ou, H. Tu, B. Shan, A. Luk, R.A. DeBose-Boyd, Y. Bashmakov, J.L. Goldstein, and M.S. Brown Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR Proc. Natl. Acad. Sci. U S A 98 2001 6027 6032
-
(2001)
Proc. Natl. Acad. Sci. U S A
, vol.98
, pp. 6027-6032
-
-
Ou, J.1
Tu, H.2
Shan, B.3
Luk, A.4
Debose-Boyd, R.A.5
Bashmakov, Y.6
Goldstein, J.L.7
Brown, M.S.8
-
108
-
-
18544388579
-
Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements
-
T. Yoshikawa, H. Shimano, N. Yahagi, T. Ide, M. Amemiya-Kudo, T. Matsuzaka, M. Nakakuki, S. Tomita, H. Okazaki, Y. Tamura, Y. Iizuka, K. Ohashi, A. Takahashi, H. Sone, J. Osuga Ji, T. Gotoda, S. Ishibashi, and N. Yamada Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements J. Biol. Chem. 277 2002 1705 1711
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1705-1711
-
-
Yoshikawa, T.1
Shimano, H.2
Yahagi, N.3
Ide, T.4
Amemiya-Kudo, M.5
Matsuzaka, T.6
Nakakuki, M.7
Tomita, S.8
Okazaki, H.9
Tamura, Y.10
Iizuka, Y.11
Ohashi, K.12
Takahashi, A.13
Sone, H.14
Osuga Ji, J.15
Gotoda, T.16
Ishibashi, S.17
Yamada, N.18
-
109
-
-
12444256363
-
Cross-talk between peroxisome proliferator-activated receptor (PPAR) α and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARS suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling
-
DOI 10.1210/me.2002-0190
-
T. Yoshikawa, T. Ide, H. Shimano, N. Yahagi, M. Amemiya-Kudo, T. Matsuzaka, S. Yatoh, T. Kitamine, H. Okazaki, Y. Tamura, M. Sekiya, A. Takahashi, A.H. Hasty, R. Sato, H. Sone, J. Osuga, S. Ishibashi, and N. Yamada Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling Mol. Endocrinol. 17 2003 1240 1254 (Pubitemid 36819948)
-
(2003)
Molecular Endocrinology
, vol.17
, Issue.7
, pp. 1240-1254
-
-
Yoshikawa, T.1
Ide, T.2
Shimano, H.3
Yahagi, N.4
Amemiya-Kudo, M.5
Matsuzaka, T.6
Yatoh, S.7
Kitamine, T.8
Okazaki, H.9
Tamura, Y.10
Sekiya, M.11
Takahashi, A.12
Hasty, A.H.13
Sato, R.14
Sone, H.15
Osuga, J.-I.16
Ishibashi, S.17
Yamada, N.18
-
110
-
-
0347356334
-
Analysis of the role of protein kinase B (cAKT) in insulin-dependent induction of glucokinase and sterol regulatory element-binding protein 1(SREBP1) mRNAs in hepatocytes
-
P.G. Ribaux, and P.B. Iynedjian Analysis of the role of protein kinase B (cAKT) in insulin-dependent induction of glucokinase and sterol regulatory element-binding protein 1(SREBP1) mRNAs in hepatocytes Biochem. J. 376 2003 697 705
-
(2003)
Biochem. J.
, vol.376
, pp. 697-705
-
-
Ribaux, P.G.1
Iynedjian, P.B.2
-
111
-
-
30844437681
-
Docosahexaneoic acid (22:6, n-3) regulates rat hepatocyte SREBP-1 nuclear abundance by Erk- and 26S proteasome-dependent pathways
-
D. Botolin, Y. Wang, B. Christian, and D.B. Jump Docosahexaneoic acid (22:6, n-3) regulates rat hepatocyte SREBP-1 nuclear abundance by Erk- and 26S proteasome-dependent pathways J. Lipid Res. 47 2006 181 192
-
(2006)
J. Lipid Res.
, vol.47
, pp. 181-192
-
-
Botolin, D.1
Wang, Y.2
Christian, B.3
Jump, D.B.4
-
112
-
-
0036291404
-
NF-Y involvement in the polyunsaturated fat inhibition of fatty acid synthase gene transcription
-
M. Teran-Garcia, C. Rufo, M.T. Nakamura, T.F. Osborne, and S.D. Clarke NF-Y involvement in the polyunsaturated fat inhibition of fatty acid synthase gene transcription Biochem. Biophys. Res. Commun. 290 2002 1295 1299
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.290
, pp. 1295-1299
-
-
Teran-Garcia, M.1
Rufo, C.2
Nakamura, M.T.3
Osborne, T.F.4
Clarke, S.D.5
-
113
-
-
33947261702
-
Polyunsaturated fatty acid suppression of fatty acid synthase (FASN): Evidence for dietary modulation of NF-Y binding to the Fasn promoter by SREBP-1c
-
M. Teran-Garcia, A.W. Adamson, G. Yu, C. Rufo, G. Suchankova, T.D. Dreesen, M. Tekle, S.D. Clarke, and T.W. Gettys Polyunsaturated fatty acid suppression of fatty acid synthase (FASN): evidence for dietary modulation of NF-Y binding to the Fasn promoter by SREBP-1c Biochem. J. 402 2007 591 600
-
(2007)
Biochem. J.
, vol.402
, pp. 591-600
-
-
Teran-Garcia, M.1
Adamson, A.W.2
Yu, G.3
Rufo, C.4
Suchankova, G.5
Dreesen, T.D.6
Tekle, M.7
Clarke, S.D.8
Gettys, T.W.9
-
114
-
-
33748655454
-
Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation
-
K. Chu, M. Miyazaki, W.C. Man, and J.M. Ntambi Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation Mol. Cell Biol. 26 2006 6786 6798
-
(2006)
Mol. Cell Biol.
, vol.26
, pp. 6786-6798
-
-
Chu, K.1
Miyazaki, M.2
Man, W.C.3
Ntambi, J.M.4
-
115
-
-
2942755860
-
Conjugated linoleic acid induces human adipocyte delipidation: Autocrine/paracrine regulation of MEK/ERK signaling by adipocytokines
-
J.M. Brown, M.S. Boysen, S. Chung, O. Fabiyi, R.F. Morrison, S. Mandrup, and M.K. McIntosh Conjugated linoleic acid induces human adipocyte delipidation: autocrine/paracrine regulation of MEK/ERK signaling by adipocytokines J. Biol. Chem. 279 2004 26735 26747
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 26735-26747
-
-
Brown, J.M.1
Boysen, M.S.2
Chung, S.3
Fabiyi, O.4
Morrison, R.F.5
Mandrup, S.6
McIntosh, M.K.7
-
116
-
-
0034814189
-
Docosahexaenoic acid modulates phorbol ester-induced activation of extracellular signal-regulated kinases 1 and 2 in NIH/3T3 cells
-
A. Denys, A. Hichami, B. Maume, and N.A. Khan Docosahexaenoic acid modulates phorbol ester-induced activation of extracellular signal-regulated kinases 1 and 2 in NIH/3T3 cells Lipids 36 2001 813 818
-
(2001)
Lipids
, vol.36
, pp. 813-818
-
-
Denys, A.1
Hichami, A.2
Maume, B.3
Khan, N.A.4
-
117
-
-
34247104457
-
Conjugated linoleic acid inhibits Caco-2 cell growth via ERK-MAPK signaling pathway
-
C. Bocca, F. Bozzo, L. Gabriel, and A. Miglietta Conjugated linoleic acid inhibits Caco-2 cell growth via ERK-MAPK signaling pathway J. Nutr. Biochem. 18 2007 332 340
-
(2007)
J. Nutr. Biochem.
, vol.18
, pp. 332-340
-
-
Bocca, C.1
Bozzo, F.2
Gabriel, L.3
Miglietta, A.4
-
118
-
-
33746764999
-
Extracellular signal-regulated kinase 1/2 and protein phosphatase 2A are involved in the antiproliferative activity of conjugated linoleic acid in MCF-7 cells
-
A. Miglietta, F. Bozzo, L. Gabriel, C. Bocca, and R.A. Canuto Extracellular signal-regulated kinase 1/2 and protein phosphatase 2A are involved in the antiproliferative activity of conjugated linoleic acid in MCF-7 cells Br. J. Nutr. 96 2006 22 27
-
(2006)
Br. J. Nutr.
, vol.96
, pp. 22-27
-
-
Miglietta, A.1
Bozzo, F.2
Gabriel, L.3
Bocca, C.4
Canuto, R.A.5
-
119
-
-
0038627973
-
Differential effects of low-dose docosahexaenoic acid and eicosapentaenoic acid on the regulation of mitogenic signaling pathways in mesangial cells
-
A.N. Yusufi, J. Cheng, M.A. Thompson, H.J. Walker, C.E. Gray, G.M. Warner, and J.P. Grande Differential effects of low-dose docosahexaenoic acid and eicosapentaenoic acid on the regulation of mitogenic signaling pathways in mesangial cells J. Lab. Clin. Med. 141 2003 318 329
-
(2003)
J. Lab. Clin. Med.
, vol.141
, pp. 318-329
-
-
Yusufi, A.N.1
Cheng, J.2
Thompson, M.A.3
Walker, H.J.4
Gray, C.E.5
Warner, G.M.6
Grande, J.P.7
-
120
-
-
0034958783
-
A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis
-
M. Miyazaki, Y.C. Kim, and J.M. Ntambi A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis J. Lipid Res. 42 2001 1018 1024
-
(2001)
J. Lipid Res.
, vol.42
, pp. 1018-1024
-
-
Miyazaki, M.1
Kim, Y.C.2
Ntambi, J.M.3
-
121
-
-
2942588527
-
Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms
-
M. Miyazaki, A. Dobrzyn, W.C. Man, K. Chu, H. Sampath, H.J. Kim, and J.M. Ntambi Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms J. Biol. Chem. 279 2004 25164 25171
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 25164-25171
-
-
Miyazaki, M.1
Dobrzyn, A.2
Man, W.C.3
Chu, K.4
Sampath, H.5
Kim, H.J.6
Ntambi, J.M.7
-
122
-
-
67650095193
-
Hypocaloric high-protein diet improves fatty liver and hypertriglyceridemia in sucrose-fed obese rats via two pathways
-
T. Uebanso, Y. Taketani, M. Fukaya, K. Sato, Y. Takei, T. Sato, N. Sawada, K. Amo, N. Harada, H. Arai, H. Yamamoto, and E. Takeda Hypocaloric high-protein diet improves fatty liver and hypertriglyceridemia in sucrose-fed obese rats via two pathways Am. J. Physiol. Endocrinol. Metab. 297 2009 E76 E84
-
(2009)
Am. J. Physiol. Endocrinol. Metab.
, vol.297
-
-
Uebanso, T.1
Taketani, Y.2
Fukaya, M.3
Sato, K.4
Takei, Y.5
Sato, T.6
Sawada, N.7
Amo, K.8
Harada, N.9
Arai, H.10
Yamamoto, H.11
Takeda, E.12
-
123
-
-
77349116808
-
Nuclear receptors and hepatic lipidogenic enzyme response to a dyslipidemic sucrose-rich diet and its reversal by fish oil n-3 polyunsaturated fatty acids
-
G.J. Hein, A.M. Bernasconi, M.A. Montanaro, M. Pellon-Maison, G. Finarelli, A. Chicco, Y.B. Lombardo, and R.R. Brenner Nuclear receptors and hepatic lipidogenic enzyme response to a dyslipidemic sucrose-rich diet and its reversal by fish oil n-3 polyunsaturated fatty acids Am. J. Physiol. Endocrinol. Metab. 298 2010 E429 E439
-
(2010)
Am. J. Physiol. Endocrinol. Metab.
, vol.298
-
-
Hein, G.J.1
Bernasconi, A.M.2
Montanaro, M.A.3
Pellon-Maison, M.4
Finarelli, G.5
Chicco, A.6
Lombardo, Y.B.7
Brenner, R.R.8
-
124
-
-
51449106076
-
ChREBP: A glucose-activated transcription factor involved in the development of metabolic syndrome
-
K. Iizuka, and Y. Horikawa ChREBP: a glucose-activated transcription factor involved in the development of metabolic syndrome Endocr. J. 55 2008 617 624
-
(2008)
Endocr. J.
, vol.55
, pp. 617-624
-
-
Iizuka, K.1
Horikawa, Y.2
-
125
-
-
0035923516
-
Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein
-
T. Kawaguchi, M. Takenoshita, T. Kabashima, and K. Uyeda Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein Proc. Natl. Acad. Sci. U S A 98 2001 13710 13715
-
(2001)
Proc. Natl. Acad. Sci. U S A
, vol.98
, pp. 13710-13715
-
-
Kawaguchi, T.1
Takenoshita, M.2
Kabashima, T.3
Uyeda, K.4
-
126
-
-
43649094366
-
Carbohydrate responsive element binding protein and lipid homeostasis
-
P.D. Denechaud, J. Girard, and C. Postic Carbohydrate responsive element binding protein and lipid homeostasis Curr. Opin. Lipidol. 19 2008 301 306
-
(2008)
Curr. Opin. Lipidol.
, vol.19
, pp. 301-306
-
-
Denechaud, P.D.1
Girard, J.2
Postic, C.3
-
127
-
-
2442435802
-
Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis
-
K. Iizuka, R.K. Bruick, G. Liang, J.D. Horton, and K. Uyeda Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis Proc. Natl. Acad. Sci. U S A 101 2004 7281 7286
-
(2004)
Proc. Natl. Acad. Sci. U S A
, vol.101
, pp. 7281-7286
-
-
Iizuka, K.1
Bruick, R.K.2
Liang, G.3
Horton, J.D.4
Uyeda, K.5
-
128
-
-
68049142428
-
Individual stearoyl-coa desaturase 1 expression modulates endoplasmic reticulum stress and inflammation in human myotubes and is associated with skeletal muscle lipid storage and insulin sensitivity in vivo
-
A. Peter, C. Weigert, H. Staiger, F. Machicao, F. Schick, J. Machann, N. Stefan, C. Thamer, H.U. Haring, and E. Schleicher Individual stearoyl-coa desaturase 1 expression modulates endoplasmic reticulum stress and inflammation in human myotubes and is associated with skeletal muscle lipid storage and insulin sensitivity in vivo Diabetes 58 2009 1757 1765
-
(2009)
Diabetes
, vol.58
, pp. 1757-1765
-
-
Peter, A.1
Weigert, C.2
Staiger, H.3
MacHicao, F.4
Schick, F.5
MacHann, J.6
Stefan, N.7
Thamer, C.8
Haring, H.U.9
Schleicher, E.10
-
129
-
-
19944430411
-
Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP
-
J. Lin, R. Yang, P.T. Tarr, P.H. Wu, C. Handschin, S. Li, W. Yang, L. Pei, M. Uldry, P. Tontonoz, C.B. Newgard, and B.M. Spiegelman Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP Cell 120 2005 261 273
-
(2005)
Cell
, vol.120
, pp. 261-273
-
-
Lin, J.1
Yang, R.2
Tarr, P.T.3
Wu, P.H.4
Handschin, C.5
Li, S.6
Yang, W.7
Pei, L.8
Uldry, M.9
Tontonoz, P.10
Newgard, C.B.11
Spiegelman, B.M.12
-
130
-
-
0022847956
-
Influence of dietary cholesterol on desaturase enzymes of rat liver microsomes
-
M.L. Garg, A.M. Snoswell, and J.R. Sabine Influence of dietary cholesterol on desaturase enzymes of rat liver microsomes Prog. Lipid Res. 25 1986 639 644
-
(1986)
Prog. Lipid Res.
, vol.25
, pp. 639-644
-
-
Garg, M.L.1
Snoswell, A.M.2
Sabine, J.R.3
-
131
-
-
0023787798
-
Dietary cholesterol and/or n-3 fatty acid modulate delta 9-desaturase activity in rat liver microsomes
-
M.L. Garg, A.A. Wierzbicki, A.B. Thomson, and M.T. Clandinin Dietary cholesterol and/or n-3 fatty acid modulate delta 9-desaturase activity in rat liver microsomes Biochim. Biophys. Acta 962 1988 330 336
-
(1988)
Biochim. Biophys. Acta
, vol.962
, pp. 330-336
-
-
Garg, M.L.1
Wierzbicki, A.A.2
Thomson, A.B.3
Clandinin, M.T.4
-
132
-
-
0031582208
-
Dietary cholesterol and the activity of stearoyl CoA desaturase in rats: Evidence for an indirect regulatory effect
-
J.M. Landau, A. Sekowski, and M.W. Hamm Dietary cholesterol and the activity of stearoyl CoA desaturase in rats: evidence for an indirect regulatory effect Biochim. Biophys. Acta 1345 1997 349 357
-
(1997)
Biochim. Biophys. Acta
, vol.1345
, pp. 349-357
-
-
Landau, J.M.1
Sekowski, A.2
Hamm, M.W.3
-
133
-
-
0036795623
-
Dietary cholesterol opposes PUFA-mediated repression of the stearoyl-CoA desaturase-1 gene by SREBP-1 independent mechanism
-
H.J. Kim, M. Miyazaki, and J.M. Ntambi Dietary cholesterol opposes PUFA-mediated repression of the stearoyl-CoA desaturase-1 gene by SREBP-1 independent mechanism J. Lipid Res. 43 2002 1750 1757
-
(2002)
J. Lipid Res.
, vol.43
, pp. 1750-1757
-
-
Kim, H.J.1
Miyazaki, M.2
Ntambi, J.M.3
-
134
-
-
0013199471
-
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha
-
D.J. Peet, S.D. Turley, W. Ma, B.A. Janowski, J.M. Lobaccaro, R.E. Hammer, and D.J. Mangelsdorf Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha Cell 93 1998 693 704
-
(1998)
Cell
, vol.93
, pp. 693-704
-
-
Peet, D.J.1
Turley, S.D.2
Ma, W.3
Janowski, B.A.4
Lobaccaro, J.M.5
Hammer, R.E.6
Mangelsdorf, D.J.7
-
135
-
-
0028909362
-
Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes. Homology to peroxisome proliferator-activated receptors
-
E.Z. Amri, F. Bonino, G. Ailhaud, N.A. Abumrad, and P.A. Grimaldi Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes. Homology to peroxisome proliferator-activated receptors J. Biol. Chem. 270 1995 2367 2371
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 2367-2371
-
-
Amri, E.Z.1
Bonino, F.2
Ailhaud, G.3
Abumrad, N.A.4
Grimaldi, P.A.5
-
136
-
-
0030952937
-
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta
-
B.M. Forman, J. Chen, and R.M. Evans Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta Proc. Natl. Acad. Sci. U S A 94 1997 4312 4317
-
(1997)
Proc. Natl. Acad. Sci. U S A
, vol.94
, pp. 4312-4317
-
-
Forman, B.M.1
Chen, J.2
Evans, R.M.3
-
137
-
-
0026551309
-
Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor
-
M. Gottlicher, E. Widmark, Q. Li, and J.A. Gustafsson Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor Proc. Natl. Acad. Sci. U S A 89 1992 4653 4657
-
(1992)
Proc. Natl. Acad. Sci. U S A
, vol.89
, pp. 4653-4657
-
-
Gottlicher, M.1
Widmark, E.2
Li, Q.3
Gustafsson, J.A.4
-
138
-
-
0006132932
-
Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma
-
S.A. Kliewer, S.S. Sundseth, S.A. Jones, P.J. Brown, G.B. Wisely, C.S. Koble, P. Devchand, W. Wahli, T.M. Willson, J.M. Lenhard, and J.M. Lehmann Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma Proc. Natl. Acad. Sci. U S A 94 1997 4318 4323
-
(1997)
Proc. Natl. Acad. Sci. U S A
, vol.94
, pp. 4318-4323
-
-
Kliewer, S.A.1
Sundseth, S.S.2
Jones, S.A.3
Brown, P.J.4
Wisely, G.B.5
Koble, C.S.6
Devchand, P.7
Wahli, W.8
Willson, T.M.9
Lenhard, J.M.10
Lehmann, J.M.11
-
139
-
-
0028802627
-
Differential activation of peroxisome proliferator-activated receptors by eicosanoids
-
K. Yu, W. Bayona, C.B. Kallen, H.P. Harding, C.P. Ravera, G. McMahon, M. Brown, and M.A. Lazar Differential activation of peroxisome proliferator- activated receptors by eicosanoids J. Biol. Chem. 270 1995 23975 23983
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23975-23983
-
-
Yu, K.1
Bayona, W.2
Kallen, C.B.3
Harding, H.P.4
Ravera, C.P.5
McMahon, G.6
Brown, M.7
Lazar, M.A.8
-
140
-
-
22544480378
-
"New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis
-
M.V. Chakravarthy, Z. Pan, Y. Zhu, K. Tordjman, J.G. Schneider, T. Coleman, J. Turk, and C.F. Semenkovich "New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis Cell Metab. 1 2005 309 322
-
(2005)
Cell Metab.
, vol.1
, pp. 309-322
-
-
Chakravarthy, M.V.1
Pan, Z.2
Zhu, Y.3
Tordjman, K.4
Schneider, J.G.5
Coleman, T.6
Turk, J.7
Semenkovich, C.F.8
-
141
-
-
70349661825
-
Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase
-
K.H. Hellemans, J.C. Hannaert, B. Denys, K.R. Steffensen, C. Raemdonck, G.A. Martens, P.P. Van Veldhoven, J.A. Gustafsson, and D. Pipeleers Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase PLoS One 4 2009 e7266
-
(2009)
PLoS One
, vol.4
, pp. 7266
-
-
Hellemans, K.H.1
Hannaert, J.C.2
Denys, B.3
Steffensen, K.R.4
Raemdonck, C.5
Martens, G.A.6
Van Veldhoven, P.P.7
Gustafsson, J.A.8
Pipeleers, D.9
-
142
-
-
51449091571
-
Impact of increased PPARgamma activity in adipocytes in vivo on adiposity, insulin sensitivity and the effects of rosiglitazone treatment
-
K. Takasawa, N. Kubota, Y. Terauchi, and T. Kadowaki Impact of increased PPARgamma activity in adipocytes in vivo on adiposity, insulin sensitivity and the effects of rosiglitazone treatment Endocr. J. 55 2008 767 776
-
(2008)
Endocr. J.
, vol.55
, pp. 767-776
-
-
Takasawa, K.1
Kubota, N.2
Terauchi, Y.3
Kadowaki, T.4
-
143
-
-
0030774054
-
Thiazolidinediones downregulate stearoyl-CoA desaturase 1 gene expression in 3T3-L1 adipocytes
-
S. Kurebayashi, T. Hirose, Y. Miyashita, S. Kasayama, and T. Kishimoto Thiazolidinediones downregulate stearoyl-CoA desaturase 1 gene expression in 3T3-L1 adipocytes Diabetes 46 1997 2115 2118
-
(1997)
Diabetes
, vol.46
, pp. 2115-2118
-
-
Kurebayashi, S.1
Hirose, T.2
Miyashita, Y.3
Kasayama, S.4
Kishimoto, T.5
-
144
-
-
0033539886
-
Regulation of stearoyl-CoA desaturase genes: Role in cellular metabolism and preadipocyte differentiation
-
Y.C. Kim, and J.M. Ntambi Regulation of stearoyl-CoA desaturase genes: role in cellular metabolism and preadipocyte differentiation Biochem. Biophys. Res. Commun. 266 1999 1 4
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.266
, pp. 1-4
-
-
Kim, Y.C.1
Ntambi, J.M.2
-
145
-
-
0033843447
-
Differential regulation of the stearoyl-CoA desaturase genes by thiazolidinediones in 3T3-L1 adipocytes
-
Y.C. Kim, F.E. Gomez, B.G. Fox, and J.M. Ntambi Differential regulation of the stearoyl-CoA desaturase genes by thiazolidinediones in 3T3-L1 adipocytes J. Lipid Res. 41 2000 1310 1316
-
(2000)
J. Lipid Res.
, vol.41
, pp. 1310-1316
-
-
Kim, Y.C.1
Gomez, F.E.2
Fox, B.G.3
Ntambi, J.M.4
-
146
-
-
57349136290
-
Stearoyl-coenzyme A desaturase 1 gene expression increases after pioglitazone treatment and is associated with peroxisomal proliferator-activated receptor-gamma responsiveness
-
A. Yao-Borengasser, N. Rassouli, V. Varma, A.M. Bodles, N. Rasouli, R. Unal, B. Phanavanh, G. Ranganathan, R.E. McGehee Jr., and P.A. Kern Stearoyl-coenzyme A desaturase 1 gene expression increases after pioglitazone treatment and is associated with peroxisomal proliferator-activated receptor-gamma responsiveness J. Clin. Endocrinol. Metab. 93 2008 4431 4439
-
(2008)
J. Clin. Endocrinol. Metab.
, vol.93
, pp. 4431-4439
-
-
Yao-Borengasser, A.1
Rassouli, N.2
Varma, V.3
Bodles, A.M.4
Rasouli, N.5
Unal, R.6
Phanavanh, B.7
Ranganathan, G.8
McGehee Jr., R.E.9
Kern, P.A.10
-
148
-
-
0025601545
-
The molecular basis for inhibition of adipose conversion of murine 3T3-L1 cells by retinoic acid
-
R.L. Stone, and D.A. Bernlohr The molecular basis for inhibition of adipose conversion of murine 3T3-L1 cells by retinoic acid Differentiation 45 1990 119 127
-
(1990)
Differentiation
, vol.45
, pp. 119-127
-
-
Stone, R.L.1
Bernlohr, D.A.2
|