Hypoxia inducible factor-1 mediates the expression of the immune checkpoint HLA-G in glioma cells through hypoxia response element located in exon 2

Oncotarget

Volumn 7, Issue 39, 2016, Pages 63690-63707

  Yaghi, Layale ^a,b,c   Poras, Isabelle ^a,b   Simoes, Renata T ^a,b,d   Donadi, Eduardo A ^e   Tost, Jörg ^f,g   Daunay, Antoine ^f   de Almeida, Bibiana Sgorla ^a,b,e   Carosella, Edgardo D ^a,b   Moreau, Philippe ^a,b  

^a SAINT LOUIS HOSPITAL   (France)

^b UNIVERSITÉ PARIS DIDEROT   (France)

^c LEBANESE UNIVERSITY   (Lebanon)

^d Instituto de Ensino e Pesquisa da Santa Casa de Belo Horizonte   (Brazil)

^e UNIVERSITY OF SÃO PAULO   (Brazil)

^f FONDATION JEAN DAUSSET CEPH   (France)

^g CENTRE NATIONAL DE GÉNOTYPAGE   (France)

Author keywords

Exon 2 HRE; Glioma; HIF 1; HLA G

Indexed keywords

DECITABINE; DEFEROXAMINE; HLA G ANTIGEN; HYPOXIA INDUCIBLE FACTOR 1; ANTINEOPLASTIC AGENT; AZACITIDINE; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA;

5' UNTRANSLATED REGION; ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DNA POLYMORPHISM; DNA RESPONSIVE ELEMENT; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE LOCUS; GENETIC TRANSCRIPTION; GLIOMA CELL; HLA G GENE; HYPOXIA RESPONSE ELEMENT; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; SINGLE NUCLEOTIDE POLYMORPHISM; UPREGULATION; ANALOGS AND DERIVATIVES; EXON; GENE; GENETIC POLYMORPHISM; GLIOMA; HUMAN; HYPOXIA; IMMUNE SYSTEM; IMMUNOLOGY; METABOLISM; PROMOTER REGION; TRANSCRIPTION INITIATION; TUMOR CELL LINE; TUMOR INVASION;

5' UNTRANSLATED REGIONS; ANTINEOPLASTIC AGENTS; AZACITIDINE; CELL LINE, TUMOR; CPG ISLANDS; DNA METHYLATION; EXONS; GENES, MHC CLASS I; GLIOMA; HLA-G ANTIGENS; HUMANS; HYPOXIA; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNE SYSTEM; NEOPLASM INVASIVENESS; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; RESPONSE ELEMENTS; TRANSCRIPTIONAL ACTIVATION;

EID: 84993953205     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.11628     Document Type: Article

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