Characterization of the human biliverdin reductase gene structure and regulatory elements: Promoter activity is enhanced by hypoxia and suppressed by TNF-α-activated NF-κB

FASEB Journal

Volumn 24, Issue 9, 2010, Pages 3239-3254

  Gibbs, Peter E M ^a   Miralem, Tihomir ^a   Maines, Mahin D ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Antioxidants; Bile pigments; Cytokines; Heme oxygenase; HIF 1; Oxidative stress

Indexed keywords

BILIRUBIN; BILIVERDIN REDUCTASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; OXIDOREDUCTASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; DNA RESPONSIVE ELEMENT; EXON; GEL MOBILITY SHIFT ASSAY; GENE STRUCTURE; HUMAN; HUMAN CELL; HYPOXIA; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY SEQUENCE;

ANOXIA; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME ACTIVATION; EXONS; HUMANS; MICROSCOPY, CONFOCAL; NF-KAPPA B; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; REGULATORY ELEMENTS, TRANSCRIPTIONAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77956638427     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-144592     Document Type: Article

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