Rescuing lymphocytes from HLA-G immunosuppressive effects mediated by the tumor microenvironment

Oncotarget

Volumn 6, Issue 35, 2015, Pages 37385-37397

  Wu, Danli ^a   Kuiaste, Isere ^b   Moreau, Philippe ^c,d   Carosella, Edgardo ^c,d   Yotnda, Patricia ^a  

^a TEXAS CHILDREN S HOSPITAL   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c SAINT LOUIS HOSPITAL   (France)

^d UNIVERSITÉ PARIS DIDEROT   (France)

Author keywords

Cancers; HLA G; ILT2; Immunosuppression; Lymphocytes

Indexed keywords

CD56 ANTIGEN; HLA G ANTIGEN; ILT2 PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; IMMUNOGLOBULIN RECEPTOR; LEUKOCYTE ANTIGEN; LILRB1 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER PATIENT; CELL MEDIATED CYTOTOXICITY; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CHEMOTAXIS; CONTROLLED STUDY; DEGRANULATION; DOWN REGULATION; EFFECTOR CELL; EMBRYO; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; IMMUNOSUPPRESSIVE TREATMENT; IN VIVO STUDY; LYMPHOCYTE; MALIGNANT TRANSFORMATION; MOUSE; NATURAL KILLER CELL; NATURAL KILLER T CELL; NONHUMAN; PROTEIN EXPRESSION; TUMOR ESCAPE; TUMOR MICROENVIRONMENT; TUMOR REGRESSION; UPREGULATION; WESTERN BLOTTING; ADOPTIVE IMMUNOTHERAPY; ANIMAL; COCULTURE; CYTOTOXICITY; DRUG SCREENING; GENETIC TRANSFECTION; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; K-562 CELL LINE; LEUKEMIA; LYMPHOCYTE ACTIVATION; METABOLISM; NONOBESE DIABETIC MOUSE; PATHOLOGY; PHENOTYPE; PROCEDURES; RNA INTERFERENCE; SCID MOUSE; SIGNAL TRANSDUCTION; TIME FACTOR; TRANSPLANTATION; TUMOR ASSOCIATED LEUKOCYTE;

ANIMALS; ANTIGENS, CD; CELL DEGRANULATION; CELL PROLIFERATION; CHEMOTAXIS; COCULTURE TECHNIQUES; CYTOTOXICITY, IMMUNOLOGIC; HEK293 CELLS; HLA-G ANTIGENS; HUMANS; IMMUNOTHERAPY, ADOPTIVE; K562 CELLS; KILLER CELLS, NATURAL; LEUKEMIA; LYMPHOCYTE ACTIVATION; LYMPHOCYTES, TUMOR-INFILTRATING; MICE, INBRED NOD; MICE, SCID; PHENOTYPE; RECEPTORS, IMMUNOLOGIC; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; TUMOR MICROENVIRONMENT; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84947729316     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.6044     Document Type: Article

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