Human airway organoid engineering as a step toward lung regeneration and disease modeling

Biomaterials

Volumn 113, Issue , 2017, Pages 118-132

  Tan, Qi ^a   Choi, Kyoung Moo ^a   Sicard, Delphine ^a   Tschumperlin, Daniel J ^a  

^a MAYO GRADUATE SCHOOL   (United States)

Author keywords

3D culture; de novo lung regeneration; Organoid implantation; Pulmonary fibrosis modeling; Self organization; YAP

Indexed keywords

BIOLOGICAL ORGANS; CELL CULTURE; CELL PROLIFERATION; CELLS; CONDENSATION; CYTOLOGY; DISEASE CONTROL; ENDOTHELIAL CELLS; TISSUE;

3-D CULTURES; BRANCHING MORPHOGENESIS; CELL BASED THERAPIES; CELL-CELL INTERACTION; DE NOVO LUNG REGENERATION; MICROVASCULAR ENDOTHELIAL CELLS; PULMONARY FIBROSIS; SELF ORGANIZATIONS;

CELL ENGINEERING;

BIOLOGICAL MARKER; MYOSIN ADENOSINE TRIPHOSPHATASE; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; AIRWAY; AIRWAY EPITHELIAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRANCHING MORPHOGENESIS; CAPILLARY ENDOTHELIAL CELL; CELL DIFFERENTIATION; CELL INTERACTION; CELL LINEAGE; CELL PLASTICITY; CELL POPULATION; CONTROLLED STUDY; ENGRAFTMENT; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMPLANTATION; KIDNEY CAPSULE; LUNG DISEASE; LUNG FIBROBLAST; LUNG PARENCHYMA; MATURATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STIMULUS RESPONSE; TISSUE ENGINEERING; TISSUE REGENERATION; TISSUE TRANSPLANTATION; ANIMAL; CELL CULTURE; CELL LINE; CYTOLOGY; ENDOTHELIUM CELL; EPITHELIUM CELL; GROWTH, DEVELOPMENT AND AGING; LUNG; MESENCHYMAL STROMA CELL; ORGAN CULTURE TECHNIQUE; ORGANOGENESIS; ORGANOID; PROCEDURES; REGENERATION; TRANSPLANTATION;

ADULT; ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELLS, CULTURED; ENDOTHELIAL CELLS; EPITHELIAL CELLS; HUMANS; LUNG; MESENCHYMAL STROMAL CELLS; MICE; ORGAN CULTURE TECHNIQUES; ORGANOGENESIS; ORGANOIDS; REGENERATION; TISSUE ENGINEERING;

EID: 84993927163     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2016.10.046     Document Type: Article

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