Medical progress: Lung transplantation

New England Journal of Medicine

Volumn 340, Issue 14, 1999, Pages 1081-1091

  Arcasoy, Selim M ^a   Kotloff, Robert M ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; LYMPHOCYTE ANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TACROLIMUS;

BLOOD TOXICITY; CHRONIC OBSTRUCTIVE LUNG DISEASE; CYSTIC FIBROSIS; EISENMENGER COMPLEX; GRAFT FAILURE; GRAFT REJECTION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LIVER TOXICITY; LUNG DISEASE; LUNG FIBROSIS; LUNG FUNCTION; LUNG TRANSPLANTATION; NEUROTOXICITY; PATIENT REFERRAL; PATIENT SELECTION; POSTOPERATIVE COMPLICATION; POSTOPERATIVE INFECTION; PRIORITY JOURNAL; PULMONARY HYPERTENSION; QUALITY OF LIFE; REVIEW; SURGICAL TECHNIQUE; SURVIVAL RATE; TREATMENT OUTCOME; HEALTH CARE ORGANIZATION; METHODOLOGY; MORTALITY; PHYSIOLOGY; SURVIVAL;

GRAFT REJECTION; HEALTH CARE RATIONING; HUMANS; LUNG TRANSPLANTATION; PATIENT SELECTION; POSTOPERATIVE COMPLICATIONS; QUALITY OF LIFE; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 0033535474     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM199904083401406     Document Type: Review

References (100)

1. 1997 Annual report of the U.S. Scientific Registry for Transplant Recipients and the Organ Procurement and Transplantation Network -transplant data: 1988-1996. Richmond, Va.: United Network for Organ Sharing, 1997.
2. Hosenpud JD, Bennett LE, Keck BM, Fiol B, Boucek MM, Novick RJ. The Registry of the International Society for Heart and Lung Transplantation: fifteenth official report - 1998. J Heart Lung Transplant 1998;17: 656-68.
3. Etienne B, Bertocchi M, Gamondes JP, Wiesendanger T, Brune J, Mornex JF. Successful double-lung transplantation for bronchioalveolar carcinoma. Chest 1997;112:1423-4.
4. Maurer JR, Frost AE, Estenne M, Higenbottam T, Glanville AR. International guidelines for the selection of lung transplant candidates. J Heart Lung Transplant 1998;17:703-9.
5. Goldberg M, Lima O, Morgan E, et al. A comparison between cyclosporin A and methylprednisolone plus azathioprine on bronchial healing following canine lung autotransplantation. J Thorac Cardiovasc Surg 1983; 85:821-6.
6. Schafers HJ, Wagner TOF, Demertzis S, et al. Preoperative corticosteroids: a contraindication to lung transplantation? Chest 1992;102: 1522-5.
7. Low DE, Trulock EP, Kaiser LR, et al. Lung transplantation of ventilator-dependent patients. Chest 1992;101:8-11.
8. Massard G, Shennib H, Metras D, et al. Double-lung transplantation in mechanically ventilated patients with cystic fibrosis. Ann Thorac Surg 1993;55:1087-92.
9. Flume PA, Egan TM, Westerman JH, et al. Lung transplantation for mechanically ventilated patients. J Heart Lung Transplant 1994;13:15-23.
10. Detterbeck FC, Egan TM, Mill MR. Lung transplantation after previous thoracic surgical procedures. Ann Thorac Surg 1995;60:139-43.
11. Dusmet M, Winton TL, Kesten S, Maurer J. Previous intrapleural procedures do not adversely affect lung transplantation. J Heart Lung Transplant 1996;15:249-54.
12. Yeatman M, McNeil K, Smith JA, et al. Lung transplantation in patients with systemic diseases: an eleven year experience at Papworth Hospital. J Heart Lung Transplant 1996;15:144-9.
13. Pigula FA, Griffith BP, Zenati MA, Dauber JH, Yousem SA, Keenan RJ. Lung transplantation for respiratory failure resulting from systemic disease. Ann Thorac Surg 1997;64:1630-4.
14. Levine SM, Anzueto A, Peters JI, Calhoon JH, Jenkinson SG, Bryan CL. Single lung transplantation in patients with systemic disease. Chest 1994;105:837-41.
15. Flume PA, Egan TM, Paradowski LJ, Detterbeck FC, Thompson JT, Yankaskas JR. Infectious complications of lung transplantation: impact of cystic fibrosis. Am J Respir Crit Care Med 1994;149:1601-7.
16. Aris RM, Gilligan PH, Neuringer IP, Gott KK, Rea J, Yankaskas JR. The effect of panresistant bacteria in cystic fibrosis patients on lung transplant outcome. Am J Respir Crit Care Med 1997;155:1699-704.
17. Snell G, de Hoyos A, Krajden M, Winton T, Maurer JR. Pseudomonas cepacia in lung transplantation recipients with cystic fibrosis. Chest 1993; 103:466-71.
18. Paradowski LJ. Saprophytic fungal infections and lung transplantation - revisited. J Heart Lung Transplant 1997;16:524-31.
19. Hauptman PJ, O'Connor KJ. Procurement and allocation of solid organs for transplantation. N Engl J Med 1997;336:422-31.
20. Hayden AM, Robert RC, Kriett JM, Smith CM, Nicholson K, Jamicson SW. Primary diagnosis predicts prognosis of lung transplant candidates. Transplantation 1993;55:1048-50.
21. Ritchie M, Waggoner AD, Davila-Roman VG, Barzilai B, Trulock EP, Eisenberg PR. Echocardiographic characterization of the improvement in right ventricular function in patients with severe pulmonary hypertension after single-lung transplantation. J Am Coll Cardiol 1993;22:1170-4.
22. Kramer MR, Valantine HA, Marshall SE, Starnes VA, Theodore J. Recovery of the right ventricle after single-lung transplantation in pulmonary hypertension. Am J Cardiol 1994;73:494-500.
23. Gammie JS, Keenan RJ, Pham SM, et al. Single-versus double-lung transplantation for pulmonary hypertension. J Thorac Cardiovasc Surg 1998;115:397-403. [Erratum, J Thorac Cardiovasc Surg 1998;115:731.]
24. Smiley RM, Navedo AT, Kirby T, Schulman LL. Postoperative independent lung ventilation in a single-lung transplant recipient. Anesthesiology 1991;74:1144-8.
25. Venuta F, De Giacomo T, Rendina EA, et al. Thoracoscopic volume reduction of the native lung after single lung transplantation for emphysema. Am J Respir Crit Care Med 1997;156:292-3.
26. Anderson MB, Kriett JM, Kapclanski DP, Perricone A, Smith CM, Jamieson SW. Volume reduction surgery in the native lung after single lung transplantation for emphysema. J Heart Lung Transplant 1997;16:752-7.
27. Sundaresan RS, Shiraishi Y, Trulock EP, et al. Single or bilateral lung transplantation for emphysema? J Thorac Cardiovasc Surg 1996;112:1485-95.
28. Bavaria JE, Kotloff RM, Palevsky H, et al. Bilateral versus single lung transplantation for chronic obstructive pulmonary disease. J Thorac Cardiovasc Surg 1997;113:520-8.
29. Starnes VA, Barr ML, Schenkel FA, et al. Experience with living-donor lobar transplantation for indications other than cystic fibrosis. J Thorac Cardiovasc Surg 1997;114:917-22.
30. Barr ML, Schenkel FA, Cohen RG, et al. Recipient and donor outcomes in living related and unrelated lobar transplantation. Transplant Proc 1998;30:2261-3.
31. Kriett JM, Smith CM, Hayden AM, et al. Lung transplantation without the use of antilymphocyte antibody preparations. J Heart Lung Transplant 1993;12:915-22.
32. Hosenpud JD, Bennett LE, Keck BM, Edwards EB, Novick RJ. Effect of diagnosis on survival benefit of lung transplantation for end-stage lung disease. Lancet 1998;351:24-7.
33. Chacon RA, Corris PA, Dark JH, Gibson GJ. Comparison of the functional results of single lung transplantation for pulmonary fibrosis and chronic airway obstruction. Thorax 1998;53:43-9.
34. Grossman RF, Frost A, Zamel N, et al. Results of single-lung transplantation for bilateral pulmonary fibrosis. N Engl J Med 1990;322:727-33.
35. 2 rebreathing in lung transplant recipients. Ann Thorac Surg 1994;58: 1709-17.
36. Sheridan PH Jr, Cheriyan A, Doud J, et al. Incidence of phrenic neuropathy after isolated lung transplantation. J Heart Lung Transplant 1995; 14:684-91.
37. Maziak DE, Maurer JR, Kesten S. Diaphragmatic paralysis: a complication of lung transplantation. Ann Thorac Surg 1996;61:170-3.
38. Pasque MK, Trulock EP, Cooper JD, et al. Single lung transplantation for pulmonary hypertension: single institution experience in 34 patients. Circulation 1995;92:2252-8.
39. Williams TJ, Patterson GA, McClean PA, Zamel N, Maurer J. Maximal exercise testing in single and double lung transplant recipients. Am Rev Respir Dis 1992;145:101-5.
40. Levy RD, Ernst P, Levine SM, et al. Exercise performance after lung transplantation. J Heart Lung Transplant 1993;12:27-33.
41. Systrom DM, Pappagianopoulos P, Fishman RS, Wain JC, Ginns LC. Determinants of abnormal maximum oxygen uptake after lung transplantation for chronic obstructive pulmonary disease. J Heart Lung Transplant 1998;17:1220-30.
42. Tirdel GB, Girgis R, Fishman RS, Theodore J. Metabolic myopathy as a cause of the exercise limitation in lung transplant recipients. J Heart Lung Transplant 1998;17:1231-7.
43. Hokanson JF, Mercier JG, Brooks GA. Cyclosporine A decreases rat skeletal muscle mitochondrial respiration in vitro. Am J Respir Crit Care Med 1995;151:1848-51.
44. Mercier JG, Hokanson JF, Brooks GA. Effects of cyclosporine A on skeletal muscle mitochondrial respiration and endurance time in rats. Am J Respir Crit Care Med 1995;151:1532-6.
45. 31P-MRS. Am J Respir Crit Care Med 1997;155:615-21.
46. Caine N, Sharples LD, Dennis C, Higenbottam TW, Wallwork J. Measurement of health-related quality of life before and after heart-lung transplantation. J Heart Lung Transplant 1996;15:1047-58.
47. Dennis C, Caine N, Sharples L, et al. Heart-lung transplantation for end-stage respiratory disease in patients with cystic fibrosis at Papworth Hospital. J Heart Lung Transplant 1993;12:893-902.
48. Gross CR, Savik K, Bolman RM III, Hertz MI. Long-term health status and quality of life outcomes of lung transplant recipients. Chest 1995; 108:1587-93.
49. Paris WP, Diercks M, Bright J, et al. Return to work after lung transplantation. J Heart Lung Transplant 1998;17:430-6.
50. Christie JD, Bavaria JE, Palevsky HI, et al. Primary graft failure following lung transplantation. Chest 1998;114:51-60.
51. Glassman LR, Keenan RJ, Fabrizio MC, et al. Extracorporeal membrane oxygenation as an adjunct treatment for primary graft failure in adult lung transplant recipients. J Thorac Cardiovasc Surg 1995;110:723-7.
52. Date H, Triantafillou AN, Trulock EP, Pohl MS, Cooper JD, Patterson GA. Inhaled nitric oxide reduces human lung allograft dysfunction. J Thorac Cardiovasc Surg 1996;111:913-9.
53. Haydock DA, Trulock EP, Kaiser LR, Knight SR, Pasque MK, Cooper JD. Management of dysfunction in the transplanted lung: experience with 7 clinical cases. Ann Thorac Surg 1992;53:635-41.
54. Novick RJ, Kaye MP, Patterson GA, et al. Redo lung transplantation: a North American-European experience. J Heart Lung Transplant 1993; 12:5-16.
55. Kshettry VR, Kroshus TJ, Hertz MI, Hunter DW, Shumway SJ, Bolman RM III. Early and late airway complications after lung transplantation: incidence and management. Ann Thorac Surg 1997,-63:1576-83.
56. Susanto I, Peters JI, Levine SM, Sako EY, Anzueto AR, Bryan CL. Use of balloon-expandable metallic stents in the management of bronchial stenosis and bronchomalacia after lung transplantation. Chest 1998;114: 1330-5.
57. Date H, Trulock EP, Arcidi JM, Sundaresan S, Cooper JD, Patterson GA. Improved airway healing after lung transplantation: an analysis of 348 bronchial anastomoses. J Thorac Cardiovasc Surg 1995;110:1424-33.
58. Kramer MR, Marshall SE, Starnes VA, Gamberg P, Amitai Z, Theodore J. Infectious complications in heart-lung transplantation: analysis in 200 episodes: Arch Intern Med 1993;153:2010-6.
59. Maurer JR, Tullis DE, Grossman RF, Vellend H, Winton TL, Patterson GA. Infectious complications following isolated lung transplantation. Chest 1992;101:1056-9.
60. Ettinger NA, Bailey TC, Trulock EP, et al. Cytomegalovirus infection and pneumonitis: impact after isolated lung transplantation. Am Rev Respir Dis 1993;147:1017-23.
61. Duncan SR, Grgurich WF, Iacono AT, et al. A comparison of ganciclovir and acyclovir to prevent cytomegalovirus after lung transplantation. Am J Respir Crit Care Med 1994;150:146-52.
62. Soghikian MV, Valentine VG, Berry GJ, Patel HR, Robbins RC, Theodore J. Impact of ganciclovir prophylaxis on heart-lung and lung transplant recipients. J Heart Lung Transplant 1996;15:881-7.
63. Cahill BC, Hibbs IR, Savik K, et al. Aspergillus airway colonization and invasive disease after lung transplantation. Chest 1997;112:1160-4.
64. Westney GE, Kesten S, De Hoyos A, Chaparro C, Winton T, Maurer JR. Aspergillus infection in single and double lung transplant recipients. Transplantation 1996;61:915-9.
65. Kramer MR, Denning DW, Marshall SE, et al. Ulcerative tracheobronchitis after lung transplantation: a new form of invasive aspergillosis. Am Rev Respir Dis 1991;144:552-6.
66. Birsan T, Taghavi S, Klepetko W. Treatment of aspergillus-related ulcerative tracheobronchitis in lung transplant recipients. J Heart Lung Transplant 1998;17:437-8.
67. Wisser W, Wekerle T, Zlabinger G, et al. Influence of human leukocyte antigen matching on long-term outcome after lung transplantation. J Heart Lung Transplant 1996;15:1209-16.
68. Schulman LL, Weinberg AD, McGregor C, Galantowicz ME, Suciu-Foca NM, Itescu S. Mismatches at the HLA-DR and HLA-B loci are risk factors for acute rejection after lung transplantation. Am J Respir Crit Care Med 1998;157:1833-7
69. Bando K, Paradis IL, Komatsu K, et al. Analysis of time-dependent risks for infection, rejection, and death after pulmonary transplantation. J Thorac Cardiovasc Surg 1995;109:49-59.
70. Trulock EP, Ettinger NA, Brunt EM, Pasque MK, Kaiser LR, Cooper JD. The role of transbronchial lung biopsy in the treatment of lung transplant recipients: an analysis of 200 consecutive procedures. Chest 1992; 102:1049-54.
71. Becker FS, Martinez FJ, Brunsting LA, Deeb GM, Flint A, Lynch JP III. Limitations of spirometry in detecting rejection after single-lung transplantation. Am J Respir Crit Care Med 1994;150:159-66.
72. Guilinger RA, Paradis IL, Dauber JH, et al. The importance of bronchoscopy with transbronchial biopsy and bronchoalveolar lavage in the management of lung transplant recipients. Am J Respir Crit Care Med 1995;152:2037-43.
73. Millet B, Higenbottam TW, Flower CDR, Stewart S, Wallwork J. The radiographic appearances of infection and acute rejection of the lung after heart-lung transplantation. Am Rev Respir Dis 1989;140:62-7.
74. Otulana BA, Higenbottam T, Ferrari L, Scott J, Igboaka G, Wallwork J The use of home spirometry in detecting acute lung rejection and infection following heart-lung transplantation. Chest 1990;97:353-7.
75. Yousem SA, Berry GJ, Cagle PT, et al. Revision of the 1990 working formulation for the classification of pulmonary allograft rejection: Lung Rejection Study Group. J Heart Lung Transplant 1996;15:1-15.
76. Sibley RK, Berry GJ, Tazelaar HD, et al. The role of transbronchial biopsies in the management of lung transplant recipients. J Heart Lung Transplant 1993;12:308-24.
77. Kesten S, Maidenberg A, Winton T, Maurer J. Treatment of presumed and proven acute rejection following six months of lung transplant survival. Am J Respir Crit Care Med 1995;152:1321-4.
78. Chamberlain D, Maurer J, Chaparro C, Idolor L. Evaluation of transbronchial lung biopsy specimens in the diagnosis of bronchiolitis obliterans after lung transplantation. J Heart Lung Transplant 1994;13:963-71.
79. Cooper JD, Billingham M, Egan T, et al. A working formulation for the standardization of nomenclature and for clinical staging of chronic dysfunction in lung allografts. J Heart Lung Transplant 1993;12:713-6.
80. Bando K, Paradis IL, Similo S, et al. Obliterative bronchiolitis after lung and heart-lung transplantation: an analysis of risk factors and management. J Thorac Cardiovasc Surg 1995;110:4-14.
81. Reichenspurner H, Girgis RE, Robbins RC, et al. Stanford experience with obliterative bronchiolitis after lung and heart-lung transplantation. Ann Thorac Surg 1996;62:1467-73.
82. Heng D, Sharples LD, McNeil K, Stewart S, Wreghitt T, Wallwork J. Bronchiolitis obliterans syndrome: incidence, natural history, prognosis, and risk factors. J Heart Lung Transplant 1998;17:1255-63.
83. Girgis RE, Tu I, Berry GJ, et al. Risk factors for the development of obliterative bronchiolitis after lung transplantation J Heart Lung Transplant 1996;15.1200-8.
84. Duncan SR, Paradis IL, Yousem SA, et al. Sequelae of cytomegalovirus pulmonary infections in lung allograft recipients. Am Rev Respir Dis 1992;146:1419-25.
85. Nathan SD, Ross DJ, Belman MJ, et al. Bronchiolitis obliterans in single-lung transplant recipients. Chest 1995;107:967-72.
86. Ikonen T, Kivisaari L, Taskinen E, Piilonen A, Harjula ALJ. High-resolution CT in long-term follow-up after lung transplantation. Chest 1997; 111:370-6.
87. Morrish WF, Herman SJ, Weisbrod GL, Chamberlain DW. Bronchiolitis obliterans after lung transplantation: findings at chest radiography and high-resolution CT. Radiology 1991;179:487-90.
88. Date H, Lynch JP, Sundaresan S, Patterson GA, Tralock EP. The impact of cytolytic therapy on bronchiolitis obliterans syndrome. J Heart Lung Transplant 1998;17:869-75.
89. Dusmet M, Maurer J, Winton T, Kesten S. Methotrexate can halt the progression of bronchiolitis obliterans syndrome in lung transplant recipients. J Heart Lung Transplant 1996;15:948-54.
90. Kesten S, Chaparro C, Scavuzzo M, Gutierrez C. Tacrolimus as rescue therapy for bronchiolitis obtiterans syndrome. J Heart Lung Transplant 1997;16:905-12.
91. Iacono AT, Keenan RJ, Duncan SR, et al. Aerosolized cyclosporine in lung recipients with refractory chronic rejection. Am J Respir Crit Care Med 1996;153:1451-5.
92. Novick RJ, Stitt LW, Al-Kattan K, et al. Pulmonary retransplantation: predictors of graft function and survival in 230 patients: Pulmonary Retransplant Registry. Ann Thorac Surg 1998;65:227-34.
93. Tamm M, Sharples LD, Higenbottam TW, Stewart S, Wallwork J. Bronchiolitis obliterans syndrome in heart-lung transplantation: surveillance biopsies. Am J Respir Crit Care Med 1997;155:1705-10.
94. Keenan RJ, Konishi H, Kawai A, et al. Clinical trial of tacrolimus versus cyclosporine in lung transplantation. Ann Thorac Surg 1995;60:580-5.
95. Dorling A, Riesbeck K, Warrens A, Lcchler R. Clinical xenotransplantation of solid organs. Lancet 1997;349:867-71.
96. Hausen B, Morris RE. Review of immunosuppression for lung transplantation: novel drugs, new uses for conventional immunosuppressants, and alternative strategies. Clin Chest Med 1997;18:353-66.
97. Pham SM, Mitruka SN, Youm W, et al. Mixed hematopoietic chimerism induces donor-specific tolerance for lung allografts in rodents. Am J Respir Crit Care Med 1999;159:199-205.
98. Rao AS, Fontes P, Iyengar A, et al. Augmentation of chimerism with perioperative donor bone marrow infusion in organ transplant recipients: a 44 month follow-up. Transplant Proc 1997;29:1184-5.
99. Sayegh MH, Turka LA. The role of T-cell costimulatory activation pathways in transplant rejection. N Engl J Med 1998;338:1813-21.
100. Azuma H, Chandrakcr A, Nadcau K, et al. Blockade of T-cell costimulation prevents development of experimental chronic renal allograft rejection. Proc Natl Acad Sci U S A 1996;93:12439-44.