Cerebral organoids model human brain development and microcephaly

Movement Disorders

Volumn 29, Issue 2, 2014, Pages 185-185

  Hattori, Nobutaka ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; BRAIN; HUMANS; MICROCEPHALY; MODELS, BIOLOGICAL; ORGANOIDS; TISSUE CULTURE TECHNIQUES;

EID: 84894225353     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.25740     Document Type: Editorial

References (5)

1. Gotz M, Huttner WB. The cell biology of neurogenesis. Nat Rev Mol Cell Biol 2005;6:777-788.
2. Zecevic N, Chen Y, Filipovic R. Contributions of cortical subventricular zone to the development of the human cerebral cortex. J Comp Neurol. 2005;491: 109-122.
3. Cox J, Jackson AP, Bond J, Woods, CG. What primary microcephaly can tell us about brain growth. Trends Mol Med 2006;12:358-366.
4. Bond J, Roberts E, Springell K, et al. A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size. Nat Genet 2005;37:353-355.
5. Pagnamenta AT, Murray JE, Yoon G, et al. A novel nonsense CDK5RAP2 mutation in a Somali child with primary microcephaly and sensorineural hearing loss. Am J Med Genet A 2012;158A:2577-2582.