메뉴 건너뛰기




Volumn 87, Issue 17, 2013, Pages 9813-9821

Rotavirus NSP1 Mediates Degradation of Interferon Regulatory Factors through Targeting of the Dimerization Domain

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON REGULATORY FACTOR; INTERFERON REGULATORY FACTOR 1; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; INTERFERON REGULATORY FACTOR 9; NONSTRUCTURAL PROTEIN 1; STAT PROTEIN;

EID: 84883289749     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01146-13     Document Type: Article
Times cited : (55)

References (65)
  • 1
    • 77449101221 scopus 로고    scopus 로고
    • Regulation of immunity and oncogenesis by the IRF transcription factor family
    • Savitsky D, Tamura T, Yanai H, Taniguchi T. 2010. Regulation of immunity and oncogenesis by the IRF transcription factor family. Cancer Immunol. Immunother. 59:489-510.
    • (2010) Cancer Immunol. Immunother , vol.59 , pp. 489-510
    • Savitsky, D.1    Tamura, T.2    Yanai, H.3    Taniguchi, T.4
  • 5
    • 34347244891 scopus 로고    scopus 로고
    • The IRF family, revisited
    • Paun A, Pitha PM. 2007. The IRF family, revisited. Biochimie 89:744-753.
    • (2007) Biochimie , vol.89 , pp. 744-753
    • Paun, A.1    Pitha, P.M.2
  • 6
    • 79959634861 scopus 로고    scopus 로고
    • Pattern recognition receptors and the innate immune response to viral infection
    • Thompson MR, Kaminski JJ, Kurt-Jones EA, Fitzgerald KA. 2011. Pattern recognition receptors and the innate immune response to viral infection. Viruses 3:920-940.
    • (2011) Viruses , vol.3 , pp. 920-940
    • Thompson, M.R.1    Kaminski, J.J.2    Kurt-Jones, E.A.3    Fitzgerald, K.A.4
  • 7
    • 84857969026 scopus 로고    scopus 로고
    • Sensing of RNA viruses: a review of innate immune receptors involved in recognizing RNA virus invasion
    • Jensen S, Thomsen AR. 2012. Sensing of RNA viruses: a review of innate immune receptors involved in recognizing RNA virus invasion. J. Virol. 86:2900-2910.
    • (2012) J. Virol , vol.86 , pp. 2900-2910
    • Jensen, S.1    Thomsen, A.R.2
  • 8
    • 75749089555 scopus 로고    scopus 로고
    • Recognition of viral nucleic acids in innate immunity
    • Yoneyama M, Fujita T. 2010. Recognition of viral nucleic acids in innate immunity. Rev. Med. Virol. 20:4-22.
    • (2010) Rev. Med. Virol , vol.20 , pp. 4-22
    • Yoneyama, M.1    Fujita, T.2
  • 9
    • 38449115829 scopus 로고    scopus 로고
    • Beyond doublestranded RNA-type I IFN induction by pppRNA and other viral nucleic acids
    • Schlee M, Barchet W, Hornung V, Hartmann G. 2007. Beyond doublestranded RNA-type I IFN induction by pppRNA and other viral nucleic acids. Curr. Top. Microbiol. Immunol. 316:207-230.
    • (2007) Curr. Top. Microbiol. Immunol , vol.316 , pp. 207-230
    • Schlee, M.1    Barchet, W.2    Hornung, V.3    Hartmann, G.4
  • 10
    • 36348940608 scopus 로고    scopus 로고
    • Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures
    • Randall RE, Goodbourn S. 2008. Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures. J. Gen. Virol. 89:1-47.
    • (2008) J. Gen. Virol , vol.89 , pp. 1-47
    • Randall, R.E.1    Goodbourn, S.2
  • 12
    • 84877656613 scopus 로고    scopus 로고
    • The IRF family of transcription factors: inception, impact and implications in oncogenesis
    • Yanai H, Negishi H, Taniguchi T. 2012. The IRF family of transcription factors: inception, impact and implications in oncogenesis. Oncoimmunology 1:1376-1386.
    • (2012) Oncoimmunology , vol.1 , pp. 1376-1386
    • Yanai, H.1    Negishi, H.2    Taniguchi, T.3
  • 13
    • 0033568642 scopus 로고    scopus 로고
    • Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences
    • Fujii Y, Shimizu T, Kusumoto M, Kyogoku Y, Taniguchi T, Hakoshima T. 1999. Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences. EMBO J. 18:5028-5041.
    • (1999) EMBO J , vol.18 , pp. 5028-5041
    • Fujii, Y.1    Shimizu, T.2    Kusumoto, M.3    Kyogoku, Y.4    Taniguchi, T.5    Hakoshima, T.6
  • 14
    • 34250017968 scopus 로고    scopus 로고
    • An atomic model of the interferon-beta enhanceosome
    • Panne D, Maniatis T, Harrison SC. 2007. An atomic model of the interferon-beta enhanceosome. Cell 129:1111-1123.
    • (2007) Cell , vol.129 , pp. 1111-1123
    • Panne, D.1    Maniatis, T.2    Harrison, S.C.3
  • 15
    • 0031933646 scopus 로고    scopus 로고
    • Structure of IRF-1 with bound DNA reveals determinants of interferon regulation
    • Escalante CR, Yie J, Thanos D, Aggarwal AK. 1998. Structure of IRF-1 with bound DNA reveals determinants of interferon regulation. Nature 391:103-106.
    • (1998) Nature , vol.391 , pp. 103-106
    • Escalante, C.R.1    Yie, J.2    Thanos, D.3    Aggarwal, A.K.4
  • 17
    • 30444458235 scopus 로고    scopus 로고
    • Stats: multifaceted regulators of transcription
    • Brierley MM, Fish EN. 2005. Stats: multifaceted regulators of transcription. J. Interferon Cytokine Res. 25:733-744.
    • (2005) J. Interferon Cytokine Res , vol.25 , pp. 733-744
    • Brierley, M.M.1    Fish, E.N.2
  • 18
    • 0036176484 scopus 로고    scopus 로고
    • Nuclear/cytoplasmic localization of IRFs in response to viral infection or interferon stimulation
    • Reich NC. 2002. Nuclear/cytoplasmic localization of IRFs in response to viral infection or interferon stimulation. J. Interferon Cytokine Res. 22: 103-109.
    • (2002) J. Interferon Cytokine Res , vol.22 , pp. 103-109
    • Reich, N.C.1
  • 19
    • 0036311933 scopus 로고    scopus 로고
    • Multiple regulatory domains of IRF-5 control activation, cellular localization, and induction of chemokines that mediate recruitment of T lymphocytes
    • Barnes BJ, Kellum MJ, Field AE, Pitha PM. 2002. Multiple regulatory domains of IRF-5 control activation, cellular localization, and induction of chemokines that mediate recruitment of T lymphocytes. Mol. Cell. Biol. 22:5721-5740.
    • (2002) Mol. Cell. Biol , vol.22 , pp. 5721-5740
    • Barnes, B.J.1    Kellum, M.J.2    Field, A.E.3    Pitha, P.M.4
  • 20
    • 0032915860 scopus 로고    scopus 로고
    • Structural and functional analysis of interferon regulatory factor 3: localization of the transactivation and autoinhibitory domains
    • Lin R, Mamane Y, Hiscott J. 1999. Structural and functional analysis of interferon regulatory factor 3: localization of the transactivation and autoinhibitory domains. Mol. Cell. Biol. 19:2465-2474.
    • (1999) Mol. Cell. Biol , vol.19 , pp. 2465-2474
    • Lin, R.1    Mamane, Y.2    Hiscott, J.3
  • 21
    • 0033842515 scopus 로고    scopus 로고
    • Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7
    • Lin R, Genin P, Mamane Y, Hiscott J. 2000. Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7. Mol. Cell. Biol. 20:6342-6353.
    • (2000) Mol. Cell. Biol , vol.20 , pp. 6342-6353
    • Lin, R.1    Genin, P.2    Mamane, Y.3    Hiscott, J.4
  • 24
    • 0031893220 scopus 로고    scopus 로고
    • Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation
    • Lin R, Heylbroeck C, Pitha PM, Hiscott J. 1998. Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation. Mol. Cell. Biol. 18:2986-2996.
    • (1998) Mol. Cell. Biol , vol.18 , pp. 2986-2996
    • Lin, R.1    Heylbroeck, C.2    Pitha, P.M.3    Hiscott, J.4
  • 25
    • 65449119503 scopus 로고    scopus 로고
    • Rotaviruses: from pathogenesis to vaccination
    • Greenberg HB, Estes MK. 2009. Rotaviruses: from pathogenesis to vaccination. Gastroenterology 136:1939-1951.
    • (2009) Gastroenterology , vol.136 , pp. 1939-1951
    • Greenberg, H.B.1    Estes, M.K.2
  • 26
    • 84856217709 scopus 로고    scopus 로고
    • WHO-Coordinated Global Rotavirus Surveillance Network.2008 Estimate of worldwide rotavirus-associated mortality in children younger than 5 years before the introduction of universal rotavirus vaccination programmes: a systematic review and meta-analysis
    • Tate JE, Burton AH, Boschi-Pinto C, Steele AD, Duque J, Parashar UD, WHO-Coordinated Global Rotavirus Surveillance Network. 2012. 2008 Estimate of worldwide rotavirus-associated mortality in children younger than 5 years before the introduction of universal rotavirus vaccination programmes: a systematic review and meta-analysis. Lancet Infect. Dis. 12:136-141.
    • (2012) Lancet Infect. Dis , vol.12 , pp. 136-141
    • Tate, J.E.1    Burton, A.H.2    Boschi-Pinto, C.3    Steele, A.D.4    Duque, J.5    Parashar, U.D.6
  • 27
    • 84865152677 scopus 로고    scopus 로고
    • Rotavirus immune responses and correlates of protection
    • Angel J, Franco MA, Greenberg HB. 2012. Rotavirus immune responses and correlates of protection. Curr. Opin. Virol. 2:419-425.
    • (2012) Curr. Opin. Virol , vol.2 , pp. 419-425
    • Angel, J.1    Franco, M.A.2    Greenberg, H.B.3
  • 28
    • 79251564770 scopus 로고    scopus 로고
    • RIG-I/MDA5/ MAVS are required to signal a protective IFN response in rotavirusinfected intestinal epithelium
    • Broquet AH, Hirata Y, McAllister CS, Kagnoff MF. 2011. RIG-I/MDA5/ MAVS are required to signal a protective IFN response in rotavirusinfected intestinal epithelium. J. Immunol. 186:1618-1626.
    • (2011) J. Immunol , vol.186 , pp. 1618-1626
    • Broquet, A.H.1    Hirata, Y.2    McAllister, C.S.3    Kagnoff, M.F.4
  • 29
    • 79952829237 scopus 로고    scopus 로고
    • The early interferon response to rotavirus is regulated by PKR and depends on MAVS/IPS-1, RIG-I, MDA-5, and IRF3
    • Sen A, Pruijssers AJ, Dermody TS, Garcĺa-Sastre A, Greenberg HB. 2011. The early interferon response to rotavirus is regulated by PKR and depends on MAVS/IPS-1, RIG-I, MDA-5, and IRF3. J. Virol. 85:3717-3732.
    • (2011) J. Virol , vol.85 , pp. 3717-3732
    • Sen, A.1    Pruijssers, A.J.2    Dermody, T.S.3    Garcĺa-Sastre, A.4    Greenberg, H.B.5
  • 30
    • 84875062319 scopus 로고    scopus 로고
    • The battle between rotavirus and its host for control of the interferon signaling pathway
    • doi:10.1371/journal.ppat.1003064
    • Arnold MM, Sen A, Greenberg HB, Patton JT. 2013. The battle between rotavirus and its host for control of the interferon signaling pathway. PLoS Pathog. 9:e1003064. doi:10.1371/journal.ppat.1003064.
    • (2013) PLoS Pathog , vol.9
    • Arnold, M.M.1    Sen, A.2    Greenberg, H.B.3    Patton, J.T.4
  • 31
    • 70349234222 scopus 로고    scopus 로고
    • Rotavirus and reovirus modulation of the interferon response
    • Sherry B. 2009. Rotavirus and reovirus modulation of the interferon response. J. Interferon Cytokine Res. 29:559-567.
    • (2009) J. Interferon Cytokine Res , vol.29 , pp. 559-567
    • Sherry, B.1
  • 33
    • 84880946564 scopus 로고    scopus 로고
    • Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence
    • doi:10.1371/journal.ppat.1003183
    • Mansur DS, Maluquer de Motes C, Unterholzner L, Sumner RP, Ferguson BJ, Ren H, Strnadova P, Bowie AG, Smith GL. 2013. Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence. PLoS Pathog. 9:e1003183. doi:10.1371/journal.ppat.1003183.
    • (2013) PLoS Pathog , vol.9
    • Mansur, D.S.1    Maluquer de Motes, C.2    Unterholzner, L.3    Sumner, R.P.4    Ferguson, B.J.5    Ren, H.6    Strnadova, P.7    Bowie, A.G.8    Smith, G.L.9
  • 34
    • 59249091837 scopus 로고    scopus 로고
    • Rotavirus NSP1 inhibits NF-kB activation by inducing proteasome-dependent degradation of beta-TrCP: a novel mechanism of IFN antagonism
    • doi:10 .1371/journal.ppat.1000280. Arnold et al
    • Graff JW, Ettayebi K, Hardy ME. 2009. Rotavirus NSP1 inhibits NF-kB activation by inducing proteasome-dependent degradation of beta-TrCP: a novel mechanism of IFN antagonism. PLoS Pathog. 5:e1000280. doi:10 .1371/journal.ppat.1000280. Arnold et al.
    • (2009) PLoS Pathog , vol.5
    • Graff, J.W.1    Ettayebi, K.2    Hardy, M.E.3
  • 36
    • 67650395630 scopus 로고    scopus 로고
    • Variation in antagonism of the interferon response to rotavirus NSP1 results in differential infectivity in mouse embryonic fibroblasts
    • Feng N, Sen A, Nguyen H, Vo P, Hoshino Y, Deal EM, Greenberg HB. 2009. Variation in antagonism of the interferon response to rotavirus NSP1 results in differential infectivity in mouse embryonic fibroblasts. J. Virol. 83:6987-6994.
    • (2009) J. Virol , vol.83 , pp. 6987-6994
    • Feng, N.1    Sen, A.2    Nguyen, H.3    Vo, P.4    Hoshino, Y.5    Deal, E.M.6    Greenberg, H.B.7
  • 37
    • 15244359631 scopus 로고    scopus 로고
    • Rotavirus nonstructural protein 1 subverts innate immune response by inducing degradation of IFN regulatory factor 3
    • Barro M, Patton JT. 2005. Rotavirus nonstructural protein 1 subverts innate immune response by inducing degradation of IFN regulatory factor 3. Proc. Natl. Acad. Sci. U. S. A. 102:4114-4119.
    • (2005) Proc. Natl. Acad. Sci. U. S. A , vol.102 , pp. 4114-4119
    • Barro, M.1    Patton, J.T.2
  • 38
    • 34247590795 scopus 로고    scopus 로고
    • Rotavirus NSP1 inhibits expression of type I interferon by antagonizing the function of interferon regulatory factors IRF3, IRF5, and IRF7
    • Barro M, Patton JT. 2007. Rotavirus NSP1 inhibits expression of type I interferon by antagonizing the function of interferon regulatory factors IRF3, IRF5, and IRF7. J. Virol. 81:4473-4481.
    • (2007) J. Virol , vol.81 , pp. 4473-4481
    • Barro, M.1    Patton, J.T.2
  • 39
    • 79551708354 scopus 로고    scopus 로고
    • Diversity of interferon antagonist activities mediated by NSP1 proteins of different rotavirus strains
    • Arnold MM, Patton JT. 2011. Diversity of interferon antagonist activities mediated by NSP1 proteins of different rotavirus strains. J. Virol. 85: 1970-1979.
    • (2011) J. Virol , vol.85 , pp. 1970-1979
    • Arnold, M.M.1    Patton, J.T.2
  • 40
    • 70349750273 scopus 로고    scopus 로고
    • IRF3 inhibition by rotavirus NSP1 is host cell and virus strain dependent but independent of NSP1 proteasomal degradation
    • Sen A, Feng N, Ettayebi K, Hardy ME, Greenberg HB. 2009. IRF3 inhibition by rotavirus NSP1 is host cell and virus strain dependent but independent of NSP1 proteasomal degradation. J. Virol. 83:10322-10335.
    • (2009) J. Virol , vol.83 , pp. 10322-10335
    • Sen, A.1    Feng, N.2    Ettayebi, K.3    Hardy, M.E.4    Greenberg, H.B.5
  • 41
    • 0027313484 scopus 로고
    • Comparative analysis of the rotavirus NS53 gene: conservation of basic and cysteine-rich regions in the protein and possible stem-loop structures in the RNA
    • Hua J, Mansell EA, Patton JT. 1993. Comparative analysis of the rotavirus NS53 gene: conservation of basic and cysteine-rich regions in the protein and possible stem-loop structures in the RNA. Virology 196:372-378.
    • (1993) Virology , vol.196 , pp. 372-378
    • Hua, J.1    Mansell, E.A.2    Patton, J.T.3
  • 42
    • 0028646206 scopus 로고
    • Molecular biology of rotaviruses. IX. Conservation and divergence in genome segment 5
    • Xu L, Tian Y, Tarlow O, Harbour D, McCrae MA. 1994. Molecular biology of rotaviruses. IX. Conservation and divergence in genome segment 5. J. Gen. Virol. 75:3413-3421.
    • (1994) J. Gen. Virol , vol.75 , pp. 3413-3421
    • Xu, L.1    Tian, Y.2    Tarlow, O.3    Harbour, D.4    McCrae, M.A.5
  • 43
    • 0027959170 scopus 로고
    • Comparison of the rotavirus nonstructural protein NSP1 (NS53) from different species by sequence analysis and northern blot hybridization
    • Dunn SJ, Cross TL, Greenberg HB. 1994. Comparison of the rotavirus nonstructural protein NSP1 (NS53) from different species by sequence analysis and northern blot hybridization. Virology 203:178-183.
    • (1994) Virology , vol.203 , pp. 178-183
    • Dunn, S.J.1    Cross, T.L.2    Greenberg, H.B.3
  • 46
    • 33847018523 scopus 로고    scopus 로고
    • Genome heterogeneity of SA11 rotavirus due to reassortment with "O" agent
    • Small C, Barro M, Brown TL, Patton JT. 2007. Genome heterogeneity of SA11 rotavirus due to reassortment with "O" agent. Virology 359:415-424.
    • (2007) Virology , vol.359 , pp. 415-424
    • Small, C.1    Barro, M.2    Brown, T.L.3    Patton, J.T.4
  • 47
    • 1642297150 scopus 로고    scopus 로고
    • Identification of Ser-386 of interferon regulatory factor 3 as critical target for inducible phosphorylation that determines activation
    • Mori M, Yoneyama M, Ito T, Takahashi K, Inagaki F, Fujita T. 2004. Identification of Ser-386 of interferon regulatory factor 3 as critical target for inducible phosphorylation that determines activation. J. Biol. Chem. 279:9698-9702.
    • (2004) J. Biol. Chem , vol.279 , pp. 9698-9702
    • Mori, M.1    Yoneyama, M.2    Ito, T.3    Takahashi, K.4    Inagaki, F.5    Fujita, T.6
  • 48
    • 52049093870 scopus 로고    scopus 로고
    • Interferon regulatory factor 4 and 8 in B-cell development
    • Lu R. 2008. Interferon regulatory factor 4 and 8 in B-cell development. Trends Immunol. 29:487-492.
    • (2008) Trends Immunol , vol.29 , pp. 487-492
    • Lu, R.1
  • 49
    • 65349182922 scopus 로고    scopus 로고
    • Rotavirus antagonizes cellular antiviral responses by inhibiting the nuclear accumulation of STAT1, STAT2, and NF-kB, J
    • Holloway G, Truong TT, Coulson BS. 2009. Rotavirus antagonizes cellular antiviral responses by inhibiting the nuclear accumulation of STAT1, STAT2, and NF-kB, J. Virol. 83:4942-4951.
    • (2009) Virol , vol.83 , pp. 4942-4951
    • Holloway, G.1    Truong, T.T.2    Coulson, B.S.3
  • 50
    • 77955880854 scopus 로고    scopus 로고
    • Interferon-lambda: a new addition to an old family
    • Donnelly RP, Kotenko SV. 2010. Interferon-lambda: a new addition to an old family. J. Interferon Cytokine Res. 30:555-564.
    • (2010) J. Interferon Cytokine Res , vol.30 , pp. 555-564
    • Donnelly, R.P.1    Kotenko, S.V.2
  • 53
    • 0037972167 scopus 로고    scopus 로고
    • Scores of RINGS but no PHDs in ubiquitin signaling
    • Aravind L, Iyer LM, Koonin EV. 2003. Scores of RINGS but no PHDs in ubiquitin signaling. Cell Cycle 2:123-126.
    • (2003) Cell Cycle , vol.2 , pp. 123-126
    • Aravind, L.1    Iyer, L.M.2    Koonin, E.V.3
  • 54
    • 33846409907 scopus 로고    scopus 로고
    • Post-translational regulation of rotavirus protein NSP1 expression in mammalian cells
    • Pina-Vazquez C, De Nova-Ocampo M, Guzman-Leon S, Padilla-Noriega L. 2007. Post-translational regulation of rotavirus protein NSP1 expression in mammalian cells. Arch. Virol. 152:345-368.
    • (2007) Arch. Virol , vol.152 , pp. 345-368
    • Pina-Vazquez, C.1    De Nova-Ocampo, M.2    Guzman-Leon, S.3    Padilla-Noriega, L.4
  • 55
    • 0032968759 scopus 로고    scopus 로고
    • Conserved transactivation domain shared by interferon regulatory factors and Smad morphogens
    • Eroshkin A, Mushegian A. 1999. Conserved transactivation domain shared by interferon regulatory factors and Smad morphogens. J. Mol. Med. (Berlin) 77:403-405.
    • (1999) J. Mol. Med. (Berlin) , vol.77 , pp. 403-405
    • Eroshkin, A.1    Mushegian, A.2
  • 56
    • 0032528041 scopus 로고    scopus 로고
    • Smad proteins exist as monomers in vivo and undergo homo-and heterooligomerization upon activation by serine/threonine kinase receptors
    • Kawabata M, Inoue H, Hanyu A, Imamura T, Miyazono K. 1998. Smad proteins exist as monomers in vivo and undergo homo-and heterooligomerization upon activation by serine/threonine kinase receptors. EMBO J. 17:4056-4065.
    • (1998) EMBO J , vol.17 , pp. 4056-4065
    • Kawabata, M.1    Inoue, H.2    Hanyu, A.3    Imamura, T.4    Miyazono, K.5
  • 59
    • 1642499349 scopus 로고    scopus 로고
    • Transforming growth factor beta/Smad3 signaling regulates IRF-7 function and transcriptional activation of the beta interferon promoter
    • Qing J, Liu C, Choy L, Wu RY, Pagano JS, Derynck R. 2004. Transforming growth factor beta/Smad3 signaling regulates IRF-7 function and transcriptional activation of the beta interferon promoter. Mol. Cell. Biol. 24:1411-1425.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 1411-1425
    • Qing, J.1    Liu, C.2    Choy, L.3    Wu, R.Y.4    Pagano, J.S.5    Derynck, R.6
  • 60
    • 84878528369 scopus 로고    scopus 로고
    • Rotavirus-encoded nonstructural protein 1 modulates cellular apoptotic machinery by targeting tumor suppressor protein p53
    • Bhowmick R, Halder UC, Chattopadhyay S, Nayak MK, Chawla-Sarkar M. 2013. Rotavirus-encoded nonstructural protein 1 modulates cellular apoptotic machinery by targeting tumor suppressor protein p53. J. Virol. 87:6840-6850.
    • (2013) J. Virol , vol.87 , pp. 6840-6850
    • Bhowmick, R.1    Halder, U.C.2    Chattopadhyay, S.3    Nayak, M.K.4    Chawla-Sarkar, M.5
  • 61
    • 77953306075 scopus 로고    scopus 로고
    • Rotavirus nonstructural protein 1 suppresses virus-induced cellular apoptosis to facilitate viral growth by activating the cell survival pathways during early stages of infection
    • Bagchi P, Dutta D, Chattopadhyay S, Mukherjee A, Halder UC, Sarkar S, Kobayashi N, Komoto S, Taniguchi K, Chawla-Sarkar M. 2010. Rotavirus nonstructural protein 1 suppresses virus-induced cellular apoptosis to facilitate viral growth by activating the cell survival pathways during early stages of infection. J. Virol. 84:6834-6845.
    • (2010) J. Virol , vol.84 , pp. 6834-6845
    • Bagchi, P.1    Dutta, D.2    Chattopadhyay, S.3    Mukherjee, A.4    Halder, U.C.5    Sarkar, S.6    Kobayashi, N.7    Komoto, S.8    Taniguchi, K.9    Chawla-Sarkar, M.10
  • 62
    • 84873880397 scopus 로고    scopus 로고
    • Molecular mechanism behind rotavirus NSP1-mediated PI3 kinase activation: interaction between NSP1 and the p85 subunit of PI3 kinase
    • Bagchi P, Nandi S, Nayak MK, Chawla-Sarkar M. 2013. Molecular mechanism behind rotavirus NSP1-mediated PI3 kinase activation: interaction between NSP1 and the p85 subunit of PI3 kinase. J. Virol. 87:2358-2362.
    • (2013) J. Virol , vol.87 , pp. 2358-2362
    • Bagchi, P.1    Nandi, S.2    Nayak, M.K.3    Chawla-Sarkar, M.4
  • 63
    • 82955246740 scopus 로고    scopus 로고
    • Rotavirus nonstructural protein 1 antagonizes innate immune response by interacting with retinoic acid inducible gene I
    • Qin L, Ren L, Zhou Z, Lei X, Chen L, Xue Q, Liu X, Wang J, Hung T. 2011. Rotavirus nonstructural protein 1 antagonizes innate immune response by interacting with retinoic acid inducible gene I. Virol. J. 8:526.
    • (2011) Virol. J , vol.8 , pp. 526
    • Qin, L.1    Ren, L.2    Zhou, Z.3    Lei, X.4    Chen, L.5    Xue, Q.6    Liu, X.7    Wang, J.8    Hung, T.9
  • 64
    • 0028284706 scopus 로고
    • Deletion mapping of the rotavirus metalloprotein NS53 (NSP1): the conserved cysteine-rich region is essential for virus-specific RNA binding
    • Hua J, Chen X, Patton JT. 1994. Deletion mapping of the rotavirus metalloprotein NS53 (NSP1): the conserved cysteine-rich region is essential for virus-specific RNA binding. J. Virol. 68:3990-4000.
    • (1994) J. Virol , vol.68 , pp. 3990-4000
    • Hua, J.1    Chen, X.2    Patton, J.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.