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Volumn 8, Issue 10, 2016, Pages

Hepatitis b virus protein x induces degradation of talin-1

Author keywords

HBV; HBV transcription; HBx; Hepatitis B virus; Protein X; TLN1; Viral restriction

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CYAN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; MESSENGER RNA; MYOSIN HEAVY CHAIN; MYOSIN HEAVY CHAIN 9; SHORT HAIRPIN RNA; TALIN; UNCLASSIFIED DRUG; VIRAL PROTEIN; VIRUS ACCESSORY PROTEIN X; HEPATITIS B VIRUS X PROTEIN; TLN1 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN;

EID: 84992365672     PISSN: None     EISSN: 19994915     Source Type: Journal    
DOI: 10.3390/v8100281     Document Type: Article
Times cited : (14)

References (78)
  • 5
    • 0034099208 scopus 로고    scopus 로고
    • Putative role of hepatitis B virus X protein in hepatocarcinogenesis: Effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways
    • Arbuthnot, P.; Capovilla, A.; Kew, M. Putative role of hepatitis B virus X protein in hepatocarcinogenesis: Effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways. J. Gastroenterol. Hepatol. 2000, 15, 357–368.
    • (2000) J. Gastroenterol. Hepatol , vol.15 , pp. 357-368
    • Arbuthnot, P.1    Capovilla, A.2    Kew, M.3
  • 6
    • 0035450252 scopus 로고    scopus 로고
    • Protein interferes with cell viability through interaction with the p127-kDa UV-damaged DNA-binding protein
    • Lin-Marq, N.; Bontron, S.; Leupin, O.; Strubin, M. Hepatitis B virus X protein interferes with cell viability through interaction with the p127-kDa UV-damaged DNA-binding protein. Virology 2001, 287, 266–274.
    • (2001) Virology , vol.287 , pp. 266-274
    • Lin-Marq, N.1    Bontron, S.2    Leupin, O.3    Strubin, M.4    Hepatitis B Virus, X.5
  • 7
    • 56149087784 scopus 로고    scopus 로고
    • Hepatitis B virus X protein affects S phase progression leading to chromosome segregation defects by binding to damaged DNA binding protein 1
    • Martin-Lluesma, S.; Schaeffer, C.; Robert, E.I.; van Breugel, P.C.; Leupin, O.; Hantz, O.; Strubin, M. Hepatitis B virus X protein affects S phase progression leading to chromosome segregation defects by binding to damaged DNA binding protein 1. Hepatology 2008, 48, 1467–1476.
    • (2008) Hepatology , vol.48 , pp. 1467-1476
    • Martin-Lluesma, S.1    Schaeffer, C.2    Robert, E.I.3    Van Breugel, P.C.4    Leupin, O.5    Hantz, O.6    Strubin, M.7
  • 8
    • 0034753082 scopus 로고    scopus 로고
    • Hepatitis B virus X protein
    • Murakami, S. Hepatitis B virus X protein: A multifunctional viral regulator. J. Gastroenterol. 2001, 36, 651–660.
    • (2001) J. Gastroenterol , vol.36 , pp. 651-660
    • Murakami, S.1
  • 11
    • 84873149342 scopus 로고    scopus 로고
    • Hepatitis B virus X protein modulates remodelling of minichromosomes related to hepatitis B virus replication in HepG2 cells
    • Luo, L.; Chen, S.; Gong, Q.; Luo, N.; Lei, Y.; Guo, J.; He, S. Hepatitis B virus X protein modulates remodelling of minichromosomes related to hepatitis B virus replication in HepG2 cells. Int. J. Mol. Med. 2013, 31, 197–204.
    • (2013) Int. J. Mol. Med , vol.31 , pp. 197-204
    • Luo, L.1    Chen, S.2    Gong, Q.3    Luo, N.4    Lei, Y.5    Guo, J.6    He, S.7
  • 12
    • 77954489756 scopus 로고    scopus 로고
    • Control of hepatitis B virus at the level of transcription
    • Quasdorff, M.; Protzer, U. Control of hepatitis B virus at the level of transcription. J. Viral Hepat. 2010, 17, 527–536.
    • (2010) J. Viral Hepat , vol.17 , pp. 527-536
    • Quasdorff, M.1    Protzer, U.2
  • 14
    • 33947413521 scopus 로고    scopus 로고
    • Enhancement of hepatitis B virus replication by the regulatory X protein in vitro and in vivo
    • Keasler, V.V.; Hodgson, A.J.; Madden, C.R.; Slagle, B.L. Enhancement of hepatitis B virus replication by the regulatory X protein in vitro and in vivo. J. Virol. 2007, 81, 2656–2662.
    • (2007) J. Virol , vol.81 , pp. 2656-2662
    • Keasler, V.V.1    Hodgson, A.J.2    Madden, C.R.3    Slagle, B.L.4
  • 16
    • 33748288087 scopus 로고    scopus 로고
    • Molecular functions and biological roles of hepatitis B virus X protein
    • Tang, H.; Oishi, N.; Kaneko, S.; Murakami, S. Molecular functions and biological roles of hepatitis B virus X protein. Cancer Sci. 2006, 97, 977–983.
    • (2006) Cancer Sci , vol.97 , pp. 977-983
    • Tang, H.1    Oishi, N.2    Kaneko, S.3    Murakami, S.4
  • 17
    • 84870522970 scopus 로고    scopus 로고
    • Hepatitis B virus X protein stimulates gene expression selectively from extrachromosomal DNA templates
    • Van Breugel, P.C.; Robert, E.I.; Mueller, H.; Decorsiere, A.; Zoulim, F.; Hantz, O.; Strubin, M. Hepatitis B virus X protein stimulates gene expression selectively from extrachromosomal DNA templates. Hepatology 2012, 56, 2116–2124.
    • (2012) Hepatology , vol.56 , pp. 2116-2124
    • Van Breugel, P.C.1    Robert, E.I.2    Mueller, H.3    Decorsiere, A.4    Zoulim, F.5    Hantz, O.6    Strubin, M.7
  • 18
    • 77955425644 scopus 로고    scopus 로고
    • Molecular biology of the hepatitis B virus and role of the X gene
    • Wei, Y.; Neuveut, C.; Tiollais, P.; Buendia, M.A. Molecular biology of the hepatitis B virus and role of the X gene. Pathol. Biol. 2010, 58, 267–272.
    • (2010) Pathol. Biol , vol.58 , pp. 267-272
    • Wei, Y.1    Neuveut, C.2    Tiollais, P.3    Buendia, M.A.4
  • 19
    • 0024240296 scopus 로고
    • A transactivating function encoded in the hepatitis B virus X gene is conserved in the integrated state
    • Wollersheim, M.; Debelka, U.; Hofschneider, P.H. A transactivating function encoded in the hepatitis B virus X gene is conserved in the integrated state. Oncogene 1988, 3, 545–552.
    • (1988) Oncogene , vol.3 , pp. 545-552
    • Wollersheim, M.1    Debelka, U.2    Hofschneider, P.H.3
  • 20
    • 17444430845 scopus 로고    scopus 로고
    • The transcriptional transactivation function of HBx protein is important for its augmentation role in hepatitis B virus replication
    • Tang, H.; Delgermaa, L.; Huang, F.; Oishi, N.; Liu, L.; He, F.; Zhao, L.; Murakami, S. The transcriptional transactivation function of HBx protein is important for its augmentation role in hepatitis B virus replication. J. Virol. 2005, 79, 5548–5556.
    • (2005) J. Virol , vol.79 , pp. 5548-5556
    • Tang, H.1    Delgermaa, L.2    Huang, F.3    Oishi, N.4    Liu, L.5    He, F.6    Zhao, L.7    Murakami, S.8
  • 21
    • 0036278326 scopus 로고    scopus 로고
    • Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex
    • Bergametti, F.; Sitterlin, D.; Transy, C. Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex. J. Virol. 2002, 76, 6495–6501.
    • (2002) J. Virol , vol.76 , pp. 6495-6501
    • Bergametti, F.1    Sitterlin, D.2    Transy, C.3
  • 22
    • 84857721968 scopus 로고    scopus 로고
    • Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replication
    • Hodgson, A.J.; Hyser, J.M.; Keasler, V.V.; Cang, Y.; Slagle, B.L. Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replication. Virology 2012, 426, 73–82.
    • (2012) Virology , vol.426 , pp. 73-82
    • Hodgson, A.J.1    Hyser, J.M.2    Keasler, V.V.3    Cang, Y.4    Slagle, B.L.5
  • 23
    • 0028853994 scopus 로고
    • Hepatitis B virus X protein interacts with a probable cellular DNA repair protein
    • Lee, T.H.; Elledge, S.J.; Butel, J.S. Hepatitis B virus X protein interacts with a probable cellular DNA repair protein. J. Virol. 1995, 69, 1107–1114.
    • (1995) J. Virol , vol.69 , pp. 1107-1114
    • Lee, T.H.1    Elledge, S.J.2    Butel, J.S.3
  • 24
    • 0038365225 scopus 로고    scopus 로고
    • Hepatitis B virus X protein and simian virus 5 V protein exhibit similar UV-DDB1 binding properties to mediate distinct activities
    • Leupin, O.; Bontron, S.; Strubin, M. Hepatitis B virus X protein and simian virus 5 V protein exhibit similar UV-DDB1 binding properties to mediate distinct activities. J. Virol. 2003, 77, 6274–6283.
    • (2003) J. Virol , vol.77 , pp. 6274-6283
    • Leupin, O.1    Bontron, S.2    Strubin, M.3
  • 25
    • 15244357567 scopus 로고    scopus 로고
    • Protein stimulates viral genome replication via a DDB1-dependent pathway distinct from that leading to cell death
    • Leupin, O.; Bontron, S.; Schaeffer, C.; Strubin, M. Hepatitis B virus X protein stimulates viral genome replication via a DDB1-dependent pathway distinct from that leading to cell death. J. Virol. 2005, 79, 4238–4245.
    • (2005) J. Virol , vol.79 , pp. 4238-4245
    • Leupin, O.1    Bontron, S.2    Schaeffer, C.3    Strubin, M.4    Hepatitis B Virus, X.5
  • 26
    • 0030844454 scopus 로고    scopus 로고
    • Interaction of the UV-damaged DNA-binding protein with hepatitis B virus X protein is conserved among mammalian hepadnaviruses and restricted to transactivation-proficient X-insertion mutants
    • Sitterlin, D.; Lee, T.H.; Prigent, S.; Tiollais, P.; Butel, J.S.; Transy, C. Interaction of the UV-damaged DNA-binding protein with hepatitis B virus X protein is conserved among mammalian hepadnaviruses and restricted to transactivation-proficient X-insertion mutants. J. Virol. 1997, 71, 6194–6199.
    • (1997) J. Virol , vol.71 , pp. 6194-6199
    • Sitterlin, D.1    Lee, T.H.2    Prigent, S.3    Tiollais, P.4    Butel, J.S.5    Transy, C.6
  • 27
    • 0034618437 scopus 로고    scopus 로고
    • Correct binding of viral X protein to UVDDB-p127 cellular protein is critical for efficient infection by hepatitis B viruses
    • Sitterlin, D.; Bergametti, F.; Tiollais, P.; Tennant, B.C.; Transy, C. Correct binding of viral X protein to UVDDB-p127 cellular protein is critical for efficient infection by hepatitis B viruses. Oncogene 2000, 19, 4427–4431.
    • (2000) Oncogene , vol.19 , pp. 4427-4431
    • Sitterlin, D.1    Bergametti, F.2    Tiollais, P.3    Tennant, B.C.4    Transy, C.5
  • 29
    • 78549238925 scopus 로고    scopus 로고
    • HIV-1 Vpr loads uracil DNA glycosylase-2 onto DCAF1, a substrate recognition subunit of a cullin 4A-ring E3 ubiquitin ligase for proteasome-dependent degradation
    • Ahn, J.; Vu, T.; Novince, Z.; Guerrero-Santoro, J.; Rapic-Otrin, V.; Gronenborn, A.M. HIV-1 Vpr loads uracil DNA glycosylase-2 onto DCAF1, a substrate recognition subunit of a cullin 4A-ring E3 ubiquitin ligase for proteasome-dependent degradation. J. Biol. Chem. 2010, 285, 37333–37341.
    • (2010) J. Biol. Chem , vol.285 , pp. 37333-37341
    • Ahn, J.1    Vu, T.2    Novince, Z.3    Guerrero-Santoro, J.4    Rapic-Otrin, V.5    Gronenborn, A.M.6
  • 30
    • 27144433162 scopus 로고    scopus 로고
    • Simian virus 5 V protein acts as an adaptor, linking DDB1 to STAT2, to facilitate the ubiquitination of STAT1
    • Precious, B.; Childs, K.; Fitzpatrick-Swallow, V.; Goodbourn, S.; Randall, R.E. Simian virus 5 V protein acts as an adaptor, linking DDB1 to STAT2, to facilitate the ubiquitination of STAT1. J. Virol. 2005, 79, 13434–13441.
    • (2005) J. Virol , vol.79 , pp. 13434-13441
    • Precious, B.1    Childs, K.2    Fitzpatrick-Swallow, V.3    Goodbourn, S.4    Randall, R.E.5
  • 31
    • 77449113802 scopus 로고    scopus 로고
    • A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery
    • Li, T.; Robert, E.I.; van Breugel, P.C.; Strubin, M.; Zheng, N. A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat. Struct. Mol. Biol. 2010, 17, 105–111.
    • (2010) Nat. Struct , vol.17 , pp. 105-111
    • Li, T.1    Robert, E.I.2    Van Breugel, P.C.3    Strubin, M.4    Zheng, N.5
  • 32
    • 16544364359 scopus 로고    scopus 로고
    • Inhibition of cellular proteasome activities enhances hepadnavirus replication in an HBX-dependent manner
    • Zhang, Z.; Protzer, U.; Hu, Z.; Jacob, J.; Liang, T.J. Inhibition of cellular proteasome activities enhances hepadnavirus replication in an HBX-dependent manner. J. Virol. 2004, 78, 4566–4572.
    • (2004) J. Virol , vol.78 , pp. 4566-4572
    • Zhang, Z.1    Protzer, U.2    Hu, Z.3    Jacob, J.4    Liang, T.J.5
  • 34
    • 77956042333 scopus 로고    scopus 로고
    • Inhibition of cellular proteasome activities mediates HBX-independent hepatitis B virus replication in vivo
    • Zhang, Z.; Sun, E.; Ou, J.H.; Liang, T.J. Inhibition of cellular proteasome activities mediates HBX-independent hepatitis B virus replication in vivo. J. Virol. 2010, 84, 9326–9331.
    • (2010) J. Virol , vol.84 , pp. 9326-9331
    • Zhang, Z.1    Sun, E.2    Ou, J.H.3    Liang, T.J.4
  • 35
    • 84869066771 scopus 로고    scopus 로고
    • The hepatitis B virus X protein inhibits thymine DNA glycosylase initiated base excision repair
    • Van de Klundert, M.A.; van Hemert, F.J.; Zaaijer, H.L.; Kootstra, N.A. The hepatitis B virus X protein inhibits thymine DNA glycosylase initiated base excision repair. PLoS ONE 2012, 7, e48940.
    • (2012) Plos ONE , vol.7
    • Van De Klundert, M.A.1    Van Hemert, F.J.2    Zaaijer, H.L.3    Kootstra, N.A.4
  • 36
    • 0034030611 scopus 로고    scopus 로고
    • Functional differences between the long terminal repeat transcriptional promoters of human immunodeficiency virus type 1 subtypes A through G
    • Jeeninga, R.E.; Hoogenkamp, M.; Armand-Ugon, M.; de, B.M.; Verhoef, K.; Berkhout, B. Functional differences between the long terminal repeat transcriptional promoters of human immunodeficiency virus type 1 subtypes A through G. J. Virol. 2000, 74, 3740–3751.
    • (2000) J. Virol , vol.74 , pp. 3740-3751
    • Jeeninga, R.E.1    Hoogenkamp, M.2    Armand-Ugon, M.3    De, B.M.4    Verhoef, K.5    Berkhout, B.6
  • 37
    • 0028338847 scopus 로고
    • Comparison of 50 and 30 long terminal repeat promoter function in human immunodeficiency virus
    • Klaver, B.; Berkhout, B. Comparison of 50 and 30 long terminal repeat promoter function in human immunodeficiency virus. J. Virol. 1994, 68, 3830–3840.
    • (1994) J. Virol , vol.68 , pp. 3830-3840
    • Klaver, B.1
  • 39
    • 0031743608 scopus 로고    scopus 로고
    • Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery
    • Zufferey, R.; Dull, T.; Mandel, R.J.; Bukovsky, A.; Quiroz, D.; Naldini, L.; Trono, D. Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J. Virol. 1998, 72, 9873–9880.
    • (1998) J. Virol , vol.72 , pp. 9873-9880
    • Zufferey, R.1    Dull, T.2    Mandel, R.J.3    Bukovsky, A.4    Quiroz, D.5    Naldini, L.6
  • 41
    • 0029829534 scopus 로고    scopus 로고
    • Two core promotor mutations identified in a hepatitis B virus strain associated with fulminant hepatitis result in enhanced viral replication
    • Baumert, T.F.; Rogers, S.A.; Hasegawa, K.; Liang, T.J. Two core promotor mutations identified in a hepatitis B virus strain associated with fulminant hepatitis result in enhanced viral replication. J. Clin. Investig. 1996, 98, 2268–2276.
    • (1996) J. Clin. Investig , vol.98 , pp. 2268-2276
    • Baumert, T.F.1    Rogers, S.A.2    Hasegawa, K.3    Liang, T.J.4
  • 42
    • 0031901220 scopus 로고    scopus 로고
    • Naturally occurring mutations define a novel function of the hepatitis B virus core promoter in core protein expression
    • Baumert, T.F.; Marrone, A.; Vergalla, J.; Liang, T.J. Naturally occurring mutations define a novel function of the hepatitis B virus core promoter in core protein expression. J. Virol. 1998, 72, 6785–6795.
    • (1998) J. Virol , vol.72 , pp. 6785-6795
    • Baumert, T.F.1    Marrone, A.2    Vergalla, J.3    Liang, T.J.4
  • 44
    • 53049104281 scopus 로고    scopus 로고
    • Bioluminescence imaging of hepatitis B virus enhancer and promoter activities in mice
    • Du, J.; Zhou, Y.; Fu, Q.X.; Gong, W.L.; Zhao, F.; Peng, J.C.; Zhan, L.S. Bioluminescence imaging of hepatitis B virus enhancer and promoter activities in mice. FEBS Lett. 2008, 582, 2556–3552.
    • (2008) FEBS Lett , vol.582 , pp. 2556-3552
    • Du, J.1    Zhou, Y.2    Fu, Q.X.3    Gong, W.L.4    Zhao, F.5    Peng, J.C.6    Zhan, L.S.7
  • 45
    • 34548178909 scopus 로고    scopus 로고
    • In-gel digestion for mass spectrometric characterization of proteins and proteomes
    • Shevchenko, A.; Tomas, H.; Havlis, J.; Olsen, J.V.; Mann, M. In-gel digestion for mass spectrometric characterization of proteins and proteomes. Nat. Protoc. 2006, 1, 2856–2860.
    • (2006) Nat. Protoc , vol.1 , pp. 2856-2860
    • Shevchenko, A.1    Tomas, H.2    Havlis, J.3    Olsen, J.V.4    Mann, M.5
  • 46
    • 0037317228 scopus 로고    scopus 로고
    • Stop and go extraction tips formatrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics
    • Ishihama, Y.; Mann, M. Stop and go extraction tips formatrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics. Anal. Chem. 2003, 75, 663–670.
    • (2003) Anal. Chem. , vol.75 , pp. 663-670
    • Ishihama, Y.1    Mann, M.2
  • 47
    • 57449099865 scopus 로고    scopus 로고
    • MaxQuant enables high peptide identification rates, individualized p.P.b.-range mass accuracies and proteome-wide protein quantification
    • Cox, J.; Mann, M. MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. Nat. Biotechnol. 2008, 26, 1367–1372.
    • (2008) Nat. Biotechnol. , vol.26 , pp. 1367-1372
    • Cox, J.1    Mann, M.2
  • 48
    • 75849153303 scopus 로고    scopus 로고
    • The Universal Protein Resource (UniProt) in 2010
    • UniProt Consortium. The Universal Protein Resource (UniProt) in 2010. Nucleic Acids Res. 2010, 38 (Database issue), D142–D148.
    • (2010) Nucleic Acids Res , vol.38 , Issue.Database issue , pp. D142-D148
  • 49
    • 84957428021 scopus 로고    scopus 로고
    • Identification of FDA-approved drugs that target hepatitis B virus transcription
    • Van de Klundert, M.A.; Zaaijer, H.L.; Kootstra, N.A. Identification of FDA-approved drugs that target hepatitis B virus transcription. J. Viral Hepat. 2016, 23, 191–201.
    • (2016) J. Viral Hepat , vol.23 , pp. 191-201
    • Van De Klundert, M.A.1    Zaaijer, H.L.2    Kootstra, N.A.3
  • 50
    • 23944462455 scopus 로고    scopus 로고
    • HBx protein of hepatitis B virus (HBV) can form complex with mitochondrial HSP60 and HSP70
    • Zhang, S.M.; Sun, D.C.; Lou, S.; Bo, X.C.; Lu, Z.; Qian, X.H.; Wang, S.Q. HBx protein of hepatitis B virus (HBV) can form complex with mitochondrial HSP60 and HSP70. Arch. Virol. 2005, 150, 1579–1590.
    • (2005) Arch. Virol , vol.150 , pp. 1579-1590
    • Zhang, S.M.1    Sun, D.C.2    Lou, S.3    Bo, X.C.4    Lu, Z.5    Qian, X.H.6    Wang, S.Q.7
  • 51
    • 84930871654 scopus 로고    scopus 로고
    • Comparative study of the different activities of hepatitis B virus whole-X protein and HBx in hepatocarcinogenesis by proteomics and bioinformatics analysis
    • Zhang, Y.; Liu, J.; Liu, H.; He, Y.; Yi, R.; Niu, Y.; Chen, T.; Yang, Q.; Zhao, Y. Comparative study of the different activities of hepatitis B virus whole-X protein and HBx in hepatocarcinogenesis by proteomics and bioinformatics analysis. Arch. Virol. 2015, 160, 1645–1656.
    • (2015) Arch. Virol , vol.160 , pp. 1645-1656
    • Zhang, Y.1    Liu, J.2    Liu, H.3    He, Y.4    Yi, R.5    Niu, Y.6    Chen, T.7    Yang, Q.8    Zhao, Y.9
  • 52
    • 34249945560 scopus 로고    scopus 로고
    • Formation of hepatitis B virus covalently closed circular DNA: Removal of genome-linked protein
    • Gao, W.; Hu, J. Formation of hepatitis B virus covalently closed circular DNA: Removal of genome-linked protein. J. Virol. 2007, 81, 6164–6174.
    • (2007) J. Virol , vol.81 , pp. 6164-6174
    • Gao, W.1    Hu, J.2
  • 54
    • 1642341451 scopus 로고    scopus 로고
    • Talin: An emerging focal point of adhesion dynamics
    • Nayal, A.; Webb, D.J.; Horwitz, A.F. Talin: An emerging focal point of adhesion dynamics. Curr. Opin. Cell Biol. 2004, 16, 94–98.
    • (2004) Curr. Opin. Cell Biol , vol.16 , pp. 94-98
    • Nayal, A.1    Webb, D.J.2    Horwitz, A.F.3
  • 55
    • 46149093439 scopus 로고    scopus 로고
    • Structural basis for the autoinhibition of talin in regulating integrin activation
    • Goksoy, E.; Ma, Y.Q.; Wang, X.; Kong, X.; Perera, D.; Plow, E.F.; Qin, J. Structural basis for the autoinhibition of talin in regulating integrin activation. Mol. Cell. 2008, 31, 124–133.
    • (2008) Mol. Cell , vol.31 , pp. 124-133
    • Goksoy, E.1    Ma, Y.Q.2    Wang, X.3    Kong, X.4    Perera, D.5    Plow, E.F.6    Qin, J.7
  • 58
    • 73249135811 scopus 로고    scopus 로고
    • Hepatitis B virus induced coupling of deadhesion and migration of HepG2 cells on thermo-responsive polymer
    • Li, X.; Feng, H.; Chen, W.N.; Chan, V. Hepatitis B virus induced coupling of deadhesion and migration of HepG2 cells on thermo-responsive polymer. Biomaterials 2010, 31, 1894–1903.
    • (2010) Biomaterials , vol.31 , pp. 1894-1903
    • Li, X.1    Feng, H.2    Chen, W.N.3    Chan, V.4
  • 59
    • 33747877768 scopus 로고    scopus 로고
    • Adhesion contact kinetics of HepG2 cells during Hepatitis B virus replication: Involvement of SH3-binding motif in HBX
    • Tan, T.L.; Feng, Z.; Lu, Y.W.; Chan, V.; Chen, W.N. Adhesion contact kinetics of HepG2 cells during Hepatitis B virus replication: Involvement of SH3-binding motif in HBX. Biochim. Biophys. Acta 2006, 1762, 755–766.
    • (2006) Biochim. Biophys. Acta , vol.1762 , pp. 755-766
    • Tan, T.L.1    Feng, Z.2    Lu, Y.W.3    Chan, V.4    Chen, W.N.5
  • 60
    • 33646193810 scopus 로고    scopus 로고
    • Activation of focal adhesion kinase by hepatitis B virus HBx protein: Multiple functions in viral replication
    • Bouchard, M.J.; Wang, L.; Schneider, R.J. Activation of focal adhesion kinase by hepatitis B virus HBx protein: Multiple functions in viral replication. J. Virol. 2006, 80, 4406–4414.
    • (2006) J. Virol , vol.80 , pp. 4406-4414
    • Bouchard, M.J.1    Wang, L.2    Schneider, R.J.3
  • 61
    • 0038021222 scopus 로고    scopus 로고
    • Epithelial cell adhesion and the regulation of gene expression
    • Balda, M.S.; Matter, K. Epithelial cell adhesion and the regulation of gene expression. Trends Cell Biol. 2003, 13, 310–318.
    • (2003) Trends Cell Biol , vol.13 , pp. 310-318
    • Balda, M.S.1    Matter, K.2
  • 62
    • 84868111953 scopus 로고    scopus 로고
    • Mechanosensitive mechanisms in transcriptional regulation
    • Mammoto, A.; Mammoto, T.; Ingber, D.E. Mechanosensitive mechanisms in transcriptional regulation. J. Cell Sci. 2012, 125, 3061–3073.
    • (2012) J. Cell Sci , vol.125 , pp. 3061-3073
    • Mammoto, A.1    Mammoto, T.2    Ingber, D.E.3
  • 63
    • 18344395156 scopus 로고    scopus 로고
    • Integrin-independent repression of cadherin transcription by talin during axis formation in Drosophila. Nat
    • Becam, I.E.; Tanentzapf, G.; Lepesant, J.A.; Brown, N.H.; Huynh, J.R. Integrin-independent repression of cadherin transcription by talin during axis formation in Drosophila. Nat. Cell Biol. 2005, 7, 510–516.
    • (2005) Cell Biol , vol.7 , pp. 510-516
    • Becam, I.E.1    Tanentzapf, G.2    Lepesant, J.A.3    Brown, N.H.4    Huynh, J.R.5
  • 64
    • 18344362078 scopus 로고    scopus 로고
    • Talin’s second persona
    • Tepass, U.; Godt, D. Talin’s second persona. Nat. Cell Biol. 2005, 7, 443–444.
    • (2005) Nat. Cell Biol , vol.7 , pp. 443-444
    • Tepass, U.1    Godt, D.2
  • 65
    • 58149520589 scopus 로고    scopus 로고
    • Polymorphisms and haplotypes in a Korean population are associated with susceptibility to chronic hepatitis and hepatocellular carcinoma
    • Lee, S.K.; Kim, M.H.; Cheong, J.Y.; Cho, S.W.; Yang, S.J.; Kwack, K. Integrin alpha V polymorphisms and haplotypes in a Korean population are associated with susceptibility to chronic hepatitis and hepatocellular carcinoma. Liver Int. 2009, 29, 187–195.
    • (2009) Liver Int , vol.29 , pp. 187-195
    • Lee, S.K.1    Kim, M.H.2    Cheong, J.Y.3    Cho, S.W.4    Yang, S.J.5    Kwack, K.6    Integrin Alpha, V.7
  • 66
    • 73949127893 scopus 로고    scopus 로고
    • Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function
    • Belloni, L.; Pollicino, T.; De, N.F.; Guerrieri, F.; Raffa, G.; Fanciulli, M.; Raimondo, G.; Levrero, M. Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function. Proc. Natl. Acad. Sci. USA 2009, 106, 19975–19979.
    • (2009) "');"> , vol.106 , pp. 19975-19979
    • Belloni, L.1    Pollicino, T.2    De, N.F.3    Guerrieri, F.4    Raffa, G.5    Fanciulli, M.6    Raimondo, G.7    Levrero, M.8
  • 68
    • 0742330524 scopus 로고    scopus 로고
    • Dictyostelium discoideum talin A is crucial for myosin II-independent and adhesion-dependent cytokinesis
    • Hibi, M.; Nagasaki, A.; Takahashi, M.; Yamagishi, A.; Uyeda, T.Q. Dictyostelium discoideum talin A is crucial for myosin II-independent and adhesion-dependent cytokinesis. J. Muscle Res. Cell Motil. 2004, 25, 127–140.
    • (2004) J. Muscle Res. Cell Motil. , vol.25 , pp. 127-140
    • Hibi, M.1    Nagasaki, A.2    Takahashi, M.3    Yamagishi, A.4    Uyeda, T.Q.5
  • 69
    • 84872147693 scopus 로고    scopus 로고
    • C-terminal truncated hepatitis B virus x protein is associated with metastasis and enhances invasiveness by C-Jun/matrix metalloproteinase protein 10 activation in hepatocellular carcinoma
    • Sze, K.M.; Chu, G.K.; Lee, J.M.; Ng, I.O. C-terminal truncated hepatitis B virus x protein is associated with metastasis and enhances invasiveness by C-Jun/matrix metalloproteinase protein 10 activation in hepatocellular carcinoma. Hepatology 2013, 57, 131–139.
    • (2013) Hepatology , vol.57 , pp. 131-139
    • Sze, K.M.1    Chu, G.K.2    Lee, J.M.3    Ng, I.O.4
  • 70
    • 0025907983 scopus 로고
    • HBx gene of hepatitis B virus induces liver cancer in transgenic mice
    • Kim, C.M.; Koike, K.; Saito, I.; Miyamura, T.; Jay, G. HBx gene of hepatitis B virus induces liver cancer in transgenic mice. Nature 1991, 351, 317–320.
    • (1991) Nature , vol.351 , pp. 317-320
    • Kim, C.M.1    Koike, K.2    Saito, I.3    Miyamura, T.4    Jay, G.5
  • 71
    • 0033058294 scopus 로고    scopus 로고
    • Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein
    • Yu, D.Y.; Moon, H.B.; Son, J.K.; Jeong, S.; Yu, S.L.; Yoon, H.; Han, Y.M.; Lee, C.S.; Park, J.S.; Lee, C.H.; et al. Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein. J. Hepatol. 1999, 31, 123–132.
    • (1999) J. Hepatol , vol.31 , pp. 123-132
    • Yu, D.Y.1    Moon, H.B.2    Son, J.K.3    Jeong, S.4    Yu, S.L.5    Yoon, H.6    Han, Y.M.7    Lee, C.S.8    Park, J.S.9    Lee, C.H.10
  • 72
    • 80051588566 scopus 로고    scopus 로고
    • Identification by differential tissue proteome analysis of talin-1 as a novel molecular marker of progression of hepatocellular carcinoma
    • Kanamori, H.; Kawakami, T.; Effendi, K.; Yamazaki, K.; Mori, T.; Ebinuma, H.; Masugi, Y.; Du, W.; Nagasaka, K.; Ogiwara, A. et al. Identification by differential tissue proteome analysis of talin-1 as a novel molecular marker of progression of hepatocellular carcinoma. Oncology 2011, 80, 406–415.
    • (2011) Oncology , vol.80 , pp. 406-415
    • Kanamori, H.1    Kawakami, T.2    Effendi, K.3    Yamazaki, K.4    Mori, T.5    Ebinuma, H.6    Masugi, Y.7    Du, W.8    Nagasaka, K.9    Ogiwara, A.10
  • 74
    • 79960361863 scopus 로고    scopus 로고
    • Focal adhesion proteins talin-1 and vinculin negatively affect paxillin phosphorylation and limit retroviral infection
    • Brown, C.; Morham, S.G.; Walsh, D.; Naghavi, M.H. Focal adhesion proteins talin-1 and vinculin negatively affect paxillin phosphorylation and limit retroviral infection. J. Mol. Biol. 2011, 410, 761–777.
    • (2011) J. Mol. Biol , vol.410 , pp. 761-777
    • Brown, C.1    Morham, S.G.2    Walsh, D.3    Naghavi, M.H.4
  • 76
    • 77953550583 scopus 로고    scopus 로고
    • Chemokine arrest signals to leukocyte integrins trigger bi-directional-occupancy of individual heterodimers by extracellular and cytoplasmic ligands
    • Alon, R. Chemokine arrest signals to leukocyte integrins trigger bi-directional-occupancy of individual heterodimers by extracellular and cytoplasmic ligands. Cell Adhes. Migr. 2010, 4, 211–214.
    • (2010) Cell Adhes. Migr , vol.4 , pp. 211-214
    • Alon, R.1
  • 77
    • 34548259213 scopus 로고    scopus 로고
    • WAVE2 regulates high-affinity integrin binding by recruiting vinculin and talin to the immunological synapse
    • Nolz, J.C.; Medeiros, R.B.; Mitchell, J.S.; Zhu, P.; Freedman, B.D.; Shimizu, Y.; Billadeau, D.D. WAVE2 regulates high-affinity integrin binding by recruiting vinculin and talin to the immunological synapse. Mol Cell Biol. 2007, 27, 5986–6000.
    • (2007) Mol Cell Biol , vol.27 , pp. 5986-6000
    • Nolz, J.C.1    Medeiros, R.B.2    Mitchell, J.S.3    Zhu, P.4    Freedman, B.D.5    Shimizu, Y.6    Billadeau, D.D.7
  • 78
    • 33751578411 scopus 로고    scopus 로고
    • Talin1 regulates TCR-mediated LFA-1 function
    • Simonson, W.T.; Franco, S.J.; Huttenlocher, A. Talin1 regulates TCR-mediated LFA-1 function. J. Immunol. 2006, 177, 7707–7714.
    • (2006) J. Immunol. , vol.177 , pp. 7707-7714
    • Simonson, W.T.1    Franco, S.J.2    Huttenlocher, A.3


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