Oxysterol-binding protein is a phosphatidylinositol 4-kinase effector required for HCV replication membrane integrity and cholesterol trafficking

Gastroenterology

Volumn 146, Issue 5, 2014, Pages

  Wang, Hongliang ^a   Perry, Jeffrey W ^a   Lauring, Adam S ^a   Neddermann, Petra ^b   De Francesco, Raffaele ^b   Tai, Andrew W ^a,c  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b Istituto Nazionale di Genetica Molecolare   (Italy)

^c Department of Physical Medicine and Rehabilitation   (United States)

Author keywords

Keywords; Lipid Kinase; Lipid Transfer Proteins; Phosphatidylinositol 4 Phosphate; Viral Replication

Indexed keywords

BINDING PROTEIN; CELL PROTEIN; CHOLESTEROL; OXYSTEROL; OXYSTEROL BINDING PROTEIN; PHOSPHATIDYLINOSITOL KINASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CHOLESTEROL SYNTHESIS; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DENGUE VIRUS; GENOTYPE; HEPATITIS C VIRUS; IMMUNOHISTOCHEMISTRY; NONHUMAN; PHENOTYPE; POLIOMYELITIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REPLICON; RNA INTERFERENCE; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; VIRUS REPLICATION;

LIPID KINASE; LIPID TRANSFER PROTEINS; PHOSPHATIDYLINOSITOL 4-PHOSPHATE; VIRAL REPLICATION;

1-PHOSPHATIDYLINOSITOL 4-KINASE; BIOLOGICAL TRANSPORT; CELL MEMBRANE; CHOLESTEROL; GENOTYPE; HEK293 CELLS; HELA CELLS; HEPACIVIRUS; HOST-PATHOGEN INTERACTIONS; HUMANS; PHENOTYPE; PHOSPHATIDYLINOSITOL PHOSPHATES; PROTEIN KINASE INHIBITORS; RECEPTORS, STEROID; RNA INTERFERENCE; RNA, VIRAL; TRANSFECTION; VIRAL NONSTRUCTURAL PROTEINS; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84898981360     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2014.02.002     Document Type: Article

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