XA four-step cycle driven by PI(4)P hydrolysis directs sterol/PI(4)P exchange by the ER-Golgi Tether OSBP

Cell

Volumn 155, Issue 4, 2013, Pages 830-

  Mesmin, Bruno ^a   Bigay, Joëlle ^a   Moser Von Filseck, Joachim ^a   Lacas Gervais, Sandra ^b   Drin, Guillaume ^a   Antonny, Bruno ^a  

^a INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b Universite Co te d'Azur Parc Valrose   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; LIPID TRANSFER PROTEIN; OXYSTEROL BINDING PROTEIN; PHOSPHATIDYLINOSITOL 4 PHOSPHATE; STEROL; UNCLASSIFIED DRUG;

ARTICLE; ENDOPLASMIC RETICULUM; GOLGI COMPLEX; LIPID TRANSPORT; NEGATIVE FEEDBACK; PHOSPHATE METABOLISM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN LIPID INTERACTION;

EID: 84887957821     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2013.09.056     Document Type: Article

References (49)

1. M. Arita, H. Kojima, T. Nagano, T. Okabe, T. Wakita, and H. Shimizu Oxysterol-binding protein family I is the target of minor enviroxime-like compounds J. Virol. 87 2013 4252 4260
2. C.T. Beh, and J. Rine A role for yeast oxysterol-binding protein homologs in endocytosis and in the maintenance of intracellular sterol-lipid distribution J. Cell Sci. 117 2004 2983 2996
3. C.T. Beh, C.R. McMaster, K.G. Kozminski, and A.K. Menon A detour for yeast oxysterol binding proteins J. Biol. Chem. 287 2012 11481 11488
4. A.W. Burgett, T.B. Poulsen, K. Wangkanont, D.R. Anderson, C. Kikuchi, K. Shimada, S. Okubo, K.C. Fortner, Y. Mimaki, and M. Kuroda Natural products reveal cancer cell dependence on oxysterol-binding proteins Nat. Chem. Biol. 7 2011 639 647
5. G. D'Angelo, E. Polishchuk, G. Di Tullio, M. Santoro, A. Di Campli, A. Godi, G. West, J. Bielawski, C.C. Chuang, and A.C. van der Spoel Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide Nature 449 2007 62 67
6. M. de Saint-Jean, V. Delfosse, D. Douguet, G. Chicanne, B. Payrastre, W. Bourguet, B. Antonny, and G. Drin Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers J. Cell Biol. 195 2011 965 978
7. J.J. Dumas, E. Merithew, E. Sudharshan, D. Rajamani, S. Hayes, D. Lawe, S. Corvera, and D.G. Lambright Multivalent endosome targeting by homodimeric EEA1 Mol. Cell 8 2001 947 958
8. F. Faulhammer, S. Kanjilal-Kolar, A. Knödler, J. Lo, Y. Lee, G. Konrad, and P. Mayinger Growth control of Golgi phosphoinositides by reciprocal localization of sac1 lipid phosphatase and pik1 4-kinase Traffic 8 2007 1554 1567
9. J.R. Friedman, and G.K. Voeltz The ER in 3D: a multifunctional dynamic membrane network Trends Cell Biol. 21 2011 709 717
10. K. Furuita, J. Jee, H. Fukada, M. Mishima, and C. Kojima Electrostatic interaction between oxysterol-binding protein and VAMP-associated protein A revealed by NMR and mutagenesis studies J. Biol. Chem. 285 2010 12961 12970
11. A. Godi, A. Di Campli, A. Konstantakopoulos, G. Di Tullio, D.R. Alessi, G.S. Kular, T. Daniele, P. Marra, J.M. Lucocq, and M.A. De Matteis FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P Nat. Cell Biol. 6 2004 393 404
12. K. Hanada, K. Kumagai, S. Yasuda, Y. Miura, M. Kawano, M. Fukasawa, and M. Nishijima Molecular machinery for non-vesicular trafficking of ceramide Nature 426 2003 803 809
13. S.C. Helle, G. Kanfer, K. Kolar, A. Lang, A.H. Michel, and B. Kornmann Organization and function of membrane contact sites Biochim. Biophys. Acta 1833 2013 2526 2541
14. Y.J. Im, S. Raychaudhuri, W.A. Prinz, and J.H. Hurley Structural mechanism for sterol sensing and transport by OSBP-related proteins Nature 437 2005 154 158
15. S.E. Kaiser, J.H. Brickner, A.R. Reilein, T.D. Fenn, P. Walter, and A.T. Brunger Structural basis of FFAT motif-mediated ER targeting Structure 13 2005 1035 1045
16. M. Kawano, K. Kumagai, M. Nishijima, and K. Hanada Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT J. Biol. Chem. 281 2006 30279 30288
17. Y.J. Kim, M.L. Hernandez, and T. Balla Inositol lipid regulation of lipid transfer in specialized membrane domains Trends Cell Biol. 23 2013 270 278
18. N. Kudo, K. Kumagai, N. Tomishige, T. Yamaji, S. Wakatsuki, M. Nishijima, K. Hanada, and R. Kato Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide Proc. Natl. Acad. Sci. USA 105 2008 488 493
19. M.S. Ladinsky, D.N. Mastronarde, J.R. McIntosh, K.E. Howell, and L.A. Staehelin Golgi structure in three dimensions: functional insights from the normal rat kidney cell J. Cell Biol. 144 1999 1135 1149
20. S. Lev Non-vesicular lipid transport by lipid-transfer proteins and beyond Nat. Rev. Mol. Cell Biol. 11 2010 739 750
21. T. Levine Short-range intracellular trafficking of small molecules across endoplasmic reticulum junctions Trends Cell Biol. 14 2004 483 490
22. T.P. Levine, and S. Munro Targeting of Golgi-specific pleckstrin homology domains involves both PtdIns 4-kinase-dependent and -independent components Curr. Biol. 12 2002 695 704
23. V. Litvak, N. Dahan, S. Ramachandran, H. Sabanay, and S. Lev Maintenance of the diacylglycerol level in the Golgi apparatus by the Nir2 protein is critical for Golgi secretory function Nat. Cell Biol. 7 2005 225 234
24. C.J. Loewen, A. Roy, and T.P. Levine A conserved ER targeting motif in three families of lipid binding proteins and in Opi1p binds VAP EMBO J. 22 2003 2025 2035
25. A.G. Manford, C.J. Stefan, H.L. Yuan, J.A. Macgurn, and S.D. Emr ER-to-plasma membrane tethering proteins regulate cell signaling and ER morphology Dev. Cell 23 2012 1129 1140
26. B. Mesmin, B. Antonny, and G. Drin Insights into the mechanisms of sterol transport between organelles Cell. Mol. Life Sci. 70 2013 3405 3421
27. V. Mikitova, and T.P. Levine Analysis of the key elements of FFAT-like motifs identifies new proteins that potentially bind VAP on the ER, including two AKAPs and FAPP2 PLoS ONE 7 2012 e30455
28. C.J. Mousley, P. Yuan, N.A. Gaur, K.D. Trettin, A.H. Nile, S.J. Deminoff, B.J. Dewar, M. Wolpert, J.M. Macdonald, and P.K. Herman A sterol-binding protein integrates endosomal lipid metabolism with TOR signaling and nitrogen sensing Cell 148 2012 702 715
29. S. Mukherjee, X. Zha, I. Tabas, and F.R. Maxfield Cholesterol distribution in living cells: fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog Biophys. J. 75 1998 1915 1925
30. F. Nakatsu, J.M. Baskin, J. Chung, L.B. Tanner, G. Shui, S.Y. Lee, M. Pirruccello, M. Hao, N.T. Ingolia, M.R. Wenk, and P. De Camilli PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity J. Cell Biol. 199 2012 1003 1016
31. M.G. Palmgren, and P. Nissen P-type ATPases Annu. Rev. Biophys. 40 2011 243 266
32. D. Peretti, N. Dahan, E. Shimoni, K. Hirschberg, and S. Lev Coordinated lipid transfer between the endoplasmic reticulum and the Golgi complex requires the VAP proteins and is essential for Golgi-mediated transport Mol. Biol. Cell 19 2008 3871 3884
33. R.J. Perry, and N.D. Ridgway Oxysterol-binding protein and vesicle-associated membrane protein-associated protein are required for sterol-dependent activation of the ceramide transport protein Mol. Biol. Cell 17 2006 2604 2616
34. S. Raychaudhuri, Y.J. Im, J.H. Hurley, and W.A. Prinz Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein-related proteins and phosphoinositides J. Cell Biol. 173 2006 107 119
35. N.D. Ridgway, P.A. Dawson, Y.K. Ho, M.S. Brown, and J.L. Goldstein Translocation of oxysterol binding protein to Golgi apparatus triggered by ligand binding J. Cell Biol. 116 1992 307 319
36. A. Roy, and T.P. Levine Multiple pools of phosphatidylinositol 4-phosphate detected using the pleckstrin homology domain of Osh2p J. Biol. Chem. 279 2004 44683 44689
37. C.J. Stefan, A.G. Manford, D. Baird, J. Yamada-Hanff, Y. Mao, and S.D. Emr Osh proteins regulate phosphoinositide metabolism at ER-plasma membrane contact sites Cell 144 2011 389 401
38. P.Y. Wang, J. Weng, and R.G. Anderson OSBP is a cholesterol-regulated scaffolding protein in control of ERK 1/2 activation Science 307 2005 1472 1476
39. M. West, N. Zurek, A. Hoenger, and G.K. Voeltz A 3D analysis of yeast ER structure reveals how ER domains are organized by membrane curvature J. Cell Biol. 193 2011 333 346
40. J. Bigay, J.F. Casella, G. Drin, B. Mesmin, and B. Antonny ArfGAP1 responds to membrane curvature through the folding of a lipid packing sensor motif EMBO J. 24 2005 2244 2253
41. T.E. Creighton Proteins. Structure and Molecular Properties Second Edition 1993 W. H. Freeman and Company New York
42. P.A. Dawson, N.D. Ridgway, C.A. Slaughter, M.S. Brown, and J.L. Goldstein cDNA cloning and expression of oxysterol-binding protein, an oligomer with a potential leucine zipper J. Biol. Chem. 264 1989 16798 16803
43. G. Drin, V. Morello, J.F. Casella, P. Gounon, and B. Antonny Asymmetric tethering of flat and curved lipid membranes by a golgin Science 320 2008 670 673
44. M. Franco, P. Chardin, M. Chabre, and S. Paris Myristoylation of ADP-ribosylation factor 1 facilitates nucleotide exchange at physiological Mg2+ levels J. Biol. Chem. 270 1995 1337 1341
45. K. John, J. Kubelt, P. Müller, D. Wüstner, and A. Herrmann Rapid transbilayer movement of the fluorescent sterol dehydroergosterol in lipid membranes Biophys. J. 83 2002 1525 1534
46. R.A. Kahn, P. Randazzo, T. Serafini, O. Weiss, C. Rulka, J. Clark, M. Amherdt, P. Roller, L. Orci, and J.E. Rothman The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport J. Biol. Chem. 267 1992 13039 13046
47. A. Lupas, M. Van Dyke, and J. Stock Predicting coiled coils from protein sequences Science 252 1991 1162 1164
48. T.J. Pucadyil, and S.L. Schmid Real-time visualization of dynamin-catalyzed membrane fission and vesicle release Cell 135 2008 1263 1275
49. J. Tong, H. Yang, H. Yang, S.H. Eom, and Y.J. Im Structure of Osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins Structure 21 2013 1203 1213