Identification of a series of compounds with potent antiviral activity for the treatment of enterovirus infections

ACS Medicinal Chemistry Letters

Volumn 4, Issue 7, 2013, Pages 585-589

  Macleod, Angus M ^a   Mitchell, Dale R ^a   Palmer, Nicholas J ^a   Van De Poël, Hervé ^a   Conrath, Katja ^c   Andrews, Martin ^c   Leyssen, Pieter ^b   Neyts, Johan ^b  

^a Medicinal Chemistry Department   (United Kingdom)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c GALAPAGOS NV   (Belgium)

Author keywords

antiviral; enterovirus; HCV; inhibitor; PI4KIII

Indexed keywords

ANTIVIRUS AGENT; BF 738735; LIPID; PHOSPHOTRANSFERASE; PLECONARIL; PYRAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; COXSACKIE VIRUS; CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; ENTEROVIRUS 71; ENTEROVIRUS INFECTION; ENZYME INHIBITION; GENOTYPE; INCIDENCE; METHYLATION; NONHUMAN; PHASE 3 CLINICAL TRIAL (TOPIC); POLIOMYELITIS VIRUS; PRIORITY JOURNAL; PROCESS OPTIMIZATION; REPLICON; VIRUS CAPSID; VIRUS INHIBITION; VIRUS REPLICATION;

EID: 84880169798     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml400095m     Document Type: Article

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