Baicalein attenuates α-synuclein aggregation, inflammasome activation and autophagy in the MPP+-treated nigrostriatal dopaminergic system in vivo

Journal of Ethnopharmacology

Volumn 194, Issue , 2016, Pages 522-529

  Hung, Kai Chih ^a   Huang, Hui Ju ^b   Wang, Yi Ting ^a   Lin, Anya Maan Yuh ^a,b  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Autophagy; Baicalein; Caspase 1; Inflammasome activation; Synuclein aggregation

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; ALPHA SYNUCLEIN; BAICALEIN; CATHEPSIN B; DOPAMINE; INFLAMMASOME; INTERLEUKIN 1BETA CONVERTING ENZYME; TYROSINE 3 MONOOXYGENASE; FLAVANONE DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; DRUG MEGADOSE; ELECTROCHEMICAL DETECTION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LOCALIZATION; ENZYME SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; IN VIVO STUDY; LOW DRUG DOSE; MALE; NEUROPROTECTION; NEUROTOXICITY; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PROTEIN AGGREGATION; RAT; SUBSTANTIA NIGRA; WESTERN BLOTTING; ANIMAL; CORPUS STRIATUM; DRUG EFFECTS; METABOLISM; SPRAGUE DAWLEY RAT;

1-METHYL-4-PHENYLPYRIDINIUM; ALPHA-SYNUCLEIN; ANIMALS; AUTOPHAGY; CORPUS STRIATUM; FLAVANONES; INFLAMMASOMES; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANTIA NIGRA;

EID: 84992215197     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2016.10.040     Document Type: Article

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