메뉴 건너뛰기




Volumn 22, Issue 1, 2017, Pages 72-85

Insights on the involvement of (–)-epigallocatechin gallate in ER stress-mediated apoptosis in age-related macular degeneration

Author keywords

Akt; AMD; Caspase; EGCG; ER mitochondrial tether site; Intracellular calcium; ROS

Indexed keywords

CALCIUM; CALNEXIN; CASPASE 12; CASPASE 3; EPIGALLOCATECHIN GALLATE; GLUCOSE REGULATED PROTEIN 78; GLYCOGEN SYNTHASE KINASE 3BETA; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN IRE1; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SERINE; THAPSIGARGIN; ANTIOXIDANT; CATECHIN;

EID: 84992206952     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-016-1318-2     Document Type: Article
Times cited : (28)

References (54)
  • 2
    • 70350238360 scopus 로고    scopus 로고
    • Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration
    • COI: 1:CAS:528:DC%2BD1MXht12qsrrL, PID: 19405847
    • Swaroop A, Chew EY, Rickman CB, Abecasis GR (2009) Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration. Annu Rev Genomics Hum Genet 10:19–43
    • (2009) Annu Rev Genomics Hum Genet , vol.10 , pp. 19-43
    • Swaroop, A.1    Chew, E.Y.2    Rickman, C.B.3    Abecasis, G.R.4
  • 3
    • 84878214672 scopus 로고    scopus 로고
    • Immunology of age-related macular degeneration
    • COI: 1:CAS:528:DC%2BC3sXotFSmurg%3D
    • Ambati J, Atkinson JP, Gelfand BD (2013) Immunology of age-related macular degeneration. Natrev Immunol 13:438–451
    • (2013) Natrev Immunol , vol.13 , pp. 438-451
    • Ambati, J.1    Atkinson, J.P.2    Gelfand, B.D.3
  • 5
    • 33646877287 scopus 로고    scopus 로고
    • Visual function and dysfunction in early and late age-related maculopathy
    • COI: 1:STN:280:DC%2BD28zivVKmsw%3D%3D, PID: 16580242
    • Hogg RE, Chakravarthy U (2006) Visual function and dysfunction in early and late age-related maculopathy. Prog Retin Eye Res 25:249–276
    • (2006) Prog Retin Eye Res , vol.25 , pp. 249-276
    • Hogg, R.E.1    Chakravarthy, U.2
  • 6
    • 77958524704 scopus 로고    scopus 로고
    • Pathway-based therapies for age-related macular degeneration: an integrated survey of emerging treatment alternatives
    • PID: 20924259
    • Zarbin MA, Rosenfeld PJ (2010) Pathway-based therapies for age-related macular degeneration: an integrated survey of emerging treatment alternatives. Retina 30:1350–1367
    • (2010) Retina , vol.30 , pp. 1350-1367
    • Zarbin, M.A.1    Rosenfeld, P.J.2
  • 8
    • 0033520657 scopus 로고    scopus 로고
    • The natural history of geographic atrophy, the advanced atrophic form of age-related macular degeneration
    • COI: 1:STN:280:DC%2BD3c%2Fjt1Squg%3D%3D, PID: 10562649
    • Sunness JS (1999) The natural history of geographic atrophy, the advanced atrophic form of age-related macular degeneration. Mol Vis 5:25
    • (1999) Mol Vis , vol.5 , pp. 25
    • Sunness, J.S.1
  • 9
    • 21244451958 scopus 로고    scopus 로고
    • The retinal pigment epithelium in visual function
    • COI: 1:CAS:528:DC%2BD2MXmsFymu7Y%3D, PID: 15987797
    • Strauss O (2005) The retinal pigment epithelium in visual function. Physiol Rev 85:845–881
    • (2005) Physiol Rev , vol.85 , pp. 845-881
    • Strauss, O.1
  • 10
    • 84938633979 scopus 로고    scopus 로고
    • Blood flow mechanics and oxygen transport and delivery in the retinal microcirculation: multiscale mathematical modeling and numerical simulation
    • Causin P, Guidoboni G, Malgaroli F, Sacco R, Harris A (2015) Blood flow mechanics and oxygen transport and delivery in the retinal microcirculation: multiscale mathematical modeling and numerical simulation. Biomechanics Modeling Mechanobiol 15:525–542
    • (2015) Biomechanics Modeling Mechanobiol , vol.15 , pp. 525-542
    • Causin, P.1    Guidoboni, G.2    Malgaroli, F.3    Sacco, R.4    Harris, A.5
  • 11
    • 84912037247 scopus 로고    scopus 로고
    • Inhibition of autophagy induces retinal pigment epithelial cell damage by the lipofuscinfluorophore A2E
    • Saadat KA, Murakami Y, Tan X, Nomura Y, Yasukawa T, Okada E, Ikeda Y, Yanagi Y (2014) Inhibition of autophagy induces retinal pigment epithelial cell damage by the lipofuscinfluorophore A2E. FEBS Open Bio 15:1007–1014
    • (2014) FEBS Open Bio , vol.15 , pp. 1007-1014
    • Saadat, K.A.1    Murakami, Y.2    Tan, X.3    Nomura, Y.4    Yasukawa, T.5    Okada, E.6    Ikeda, Y.7    Yanagi, Y.8
  • 13
    • 84925283258 scopus 로고    scopus 로고
    • PEDF improves mitochondrial function in RPE cells during oxidative stress
    • COI: 1:CAS:528:DC%2BC28XjtFyisrg%3D, PID: 25212780
    • He Y, Leung KW, Ren Y, Pei J, Ge J, Tombran-Tink J (2014) PEDF improves mitochondrial function in RPE cells during oxidative stress. Invest Ophthalmol Vis Sci 55:6742–6755
    • (2014) Invest Ophthalmol Vis Sci , vol.55 , pp. 6742-6755
    • He, Y.1    Leung, K.W.2    Ren, Y.3    Pei, J.4    Ge, J.5    Tombran-Tink, J.6
  • 15
    • 1842478123 scopus 로고    scopus 로고
    • Current concepts in the pathogenesis of age-related macular degeneration
    • PID: 15078679
    • Zarbin MA (2004) Current concepts in the pathogenesis of age-related macular degeneration. Arch Ophthalmol 122:598–614
    • (2004) Arch Ophthalmol , vol.122 , pp. 598-614
    • Zarbin, M.A.1
  • 16
    • 42049088943 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells
    • COI: 1:CAS:528:DC%2BD1cXksVaktbs%3D, PID: 18278507
    • He S, Yaung J, Kim YH, Barron E, Ryan SJ, Hinton DR (2008) Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells. Graefes Arch Clin Exp Ophthalmol 246:677–683
    • (2008) Graefes Arch Clin Exp Ophthalmol , vol.246 , pp. 677-683
    • He, S.1    Yaung, J.2    Kim, Y.H.3    Barron, E.4    Ryan, S.J.5    Hinton, D.R.6
  • 17
    • 22244446505 scopus 로고    scopus 로고
    • The mammalian unfolded protein response
    • PID: 15952902
    • Schroder M, Kaufman RJ (2005) The mammalian unfolded protein response. Annu Rev Biochem 74:739–789
    • (2005) Annu Rev Biochem , vol.74 , pp. 739-789
    • Schroder, M.1    Kaufman, R.J.2
  • 18
    • 33745747085 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and trophic factor withdrawal activate distinct signalling cascades that induce glycogen synthase kinase-3β and a caspase-9-dependent apoptosis in cerebellar granule neurons
    • COI: 1:CAS:528:DC%2BD28XmslCrur4%3D, PID: 16765055
    • Brewster JL, Linseman DA, Bouchard RJ, Loucks FA, Precht TA, Esch EA, Heidenreich KA (2006) Endoplasmic reticulum stress and trophic factor withdrawal activate distinct signalling cascades that induce glycogen synthase kinase-3β and a caspase-9-dependent apoptosis in cerebellar granule neurons. Mol Cell Neurosci 32:242–253
    • (2006) Mol Cell Neurosci , vol.32 , pp. 242-253
    • Brewster, J.L.1    Linseman, D.A.2    Bouchard, R.J.3    Loucks, F.A.4    Precht, T.A.5    Esch, E.A.6    Heidenreich, K.A.7
  • 19
    • 33748789479 scopus 로고    scopus 로고
    • Mediators of endoplasmic reticulum stress-induced apoptosis
    • COI: 1:CAS:528:DC%2BD28XptVSlsLo%3D, PID: 16953201
    • Szegezdi E, Logue SE, Gorman AM, Samali A (2006) Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep 7:880–885
    • (2006) EMBO Rep , vol.7 , pp. 880-885
    • Szegezdi, E.1    Logue, S.E.2    Gorman, A.M.3    Samali, A.4
  • 20
    • 84876032962 scopus 로고    scopus 로고
    • New directions in ER stress-induced cell death
    • PID: 23430059
    • Logue SE, Cleary P, Saveljeva S, Samali A (2013) New directions in ER stress-induced cell death. Apoptosis 18:537–546
    • (2013) Apoptosis , vol.18 , pp. 537-546
    • Logue, S.E.1    Cleary, P.2    Saveljeva, S.3    Samali, A.4
  • 21
    • 84902124271 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and the unfolded protein responses in retinal degeneration
    • COI: 1:CAS:528:DC%2BC2cXht1GqtL7O, PID: 24792589
    • Zhang SX, Sanders E, Fliesler SJ, Wang JJ (2014) Endoplasmic reticulum stress and the unfolded protein responses in retinal degeneration. Exp Eye Res 125:30–40
    • (2014) Exp Eye Res , vol.125 , pp. 30-40
    • Zhang, S.X.1    Sanders, E.2    Fliesler, S.J.3    Wang, J.J.4
  • 22
    • 33747877987 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate (EGCG): chemical and biomedical perspectives
    • COI: 1:CAS:528:DC%2BD28XovVSisL4%3D, PID: 16876833
    • Nagle DG, Ferreira D, Zhou YD (2006) Epigallocatechin-3-gallate (EGCG): chemical and biomedical perspectives. Phytochemistry 67:1849–1855
    • (2006) Phytochemistry , vol.67 , pp. 1849-1855
    • Nagle, D.G.1    Ferreira, D.2    Zhou, Y.D.3
  • 23
    • 71749106759 scopus 로고    scopus 로고
    • Oxidative mechanisms of IL-4-induced IL-6 expression in vascularendothelium
    • COI: 1:CAS:528:DC%2BD1MXhsFyku7nF, PID: 19822443
    • Lee YW, Lee WH, Kim PH (2010) Oxidative mechanisms of IL-4-induced IL-6 expression in vascularendothelium. Cytokine 49:73–79
    • (2010) Cytokine , vol.49 , pp. 73-79
    • Lee, Y.W.1    Lee, W.H.2    Kim, P.H.3
  • 24
    • 58149471999 scopus 로고    scopus 로고
    • Protective effects of (–)-epigallocatechin gallate on UVA-induced damage in ARPE19 cells
    • COI: 1:CAS:528:DC%2BD1MXnslKgug%3D%3D, PID: 19119326
    • Chan CM, Huang JH, Lin HH, Chiang HS, Chen BH, Hong JY, Hung CF (2008) Protective effects of (–)-epigallocatechin gallate on UVA-induced damage in ARPE19 cells. Mol Vis 14:2528
    • (2008) Mol Vis , vol.14 , pp. 2528
    • Chan, C.M.1    Huang, J.H.2    Lin, H.H.3    Chiang, H.S.4    Chen, B.H.5    Hong, J.Y.6    Hung, C.F.7
  • 25
    • 41649121965 scopus 로고    scopus 로고
    • Protective effects of epigallocatechin gallate after UV irradiation in cultured human retinal pigment epithelial cells
    • PID: 18063889
    • Yang SW, Lee BR, Koh JW (2007) Protective effects of epigallocatechin gallate after UV irradiation in cultured human retinal pigment epithelial cells. Korean J Ophthalmol 21:232–237
    • (2007) Korean J Ophthalmol , vol.21 , pp. 232-237
    • Yang, S.W.1    Lee, B.R.2    Koh, J.W.3
  • 26
    • 84898622055 scopus 로고    scopus 로고
    • Role of unfolded protein response dysregulation in oxidative injury of retinal pigment epithelial cells
    • COI: 1:CAS:528:DC%2BC2cXmtVWnsr8%3D, PID: 24053669
    • Chen C, Cano M, Wang JJ, Li J, Huang C, Yu Q, Herbert TP, Handa JT, Zhang SX (2014) Role of unfolded protein response dysregulation in oxidative injury of retinal pigment epithelial cells. Antioxid Redox Signal 20:2091–2106
    • (2014) Antioxid Redox Signal , vol.20 , pp. 2091-2106
    • Chen, C.1    Cano, M.2    Wang, J.J.3    Li, J.4    Huang, C.5    Yu, Q.6    Herbert, T.P.7    Handa, J.T.8    Zhang, S.X.9
  • 27
    • 84877996041 scopus 로고    scopus 로고
    • Inflammatory cytokines protect retinal pigment epithelial cells from oxidative stress-induced death
    • PID: 23705001
    • Juel HB, Faber C, Svendsen SG, Vallejo AN, Nissen MH (2013). Inflammatory cytokines protect retinal pigment epithelial cells from oxidative stress-induced death. PLoS One 8:e64619
    • (2013) PLoS One , vol.8
    • Juel, H.B.1    Faber, C.2    Svendsen, S.G.3    Vallejo, A.N.4    Nissen, M.H.5
  • 28
    • 84961057730 scopus 로고    scopus 로고
    • Role of ZnS Nanoparticles on endoplasmic reticulum stress-mediated Apoptosis in retinal pigment epithelial cells
    • COI: 1:CAS:528:DC%2BC2MXhsVentLvP, PID: 26329999
    • Karthikeyan B, Arun A, Harini L, Sundar K, Kathiresan T (2016) Role of ZnS Nanoparticles on endoplasmic reticulum stress-mediated Apoptosis in retinal pigment epithelial cells. Biol Trace Elem Res 170:390–400
    • (2016) Biol Trace Elem Res , vol.170 , pp. 390-400
    • Karthikeyan, B.1    Arun, A.2    Harini, L.3    Sundar, K.4    Kathiresan, T.5
  • 30
    • 84939808880 scopus 로고    scopus 로고
    • 4-Acetoxyphenol prevents RPE oxidative stress-induced necrosis by functioning as an NRF2 stabilizer
    • COI: 1:CAS:528:DC%2BC28Xos1Krs7k%3D, PID: 26241392
    • Hanus J, Kolkin A, Chimienti J, Botsay S, Wang S (2015) 4-Acetoxyphenol prevents RPE oxidative stress-induced necrosis by functioning as an NRF2 stabilizer. Invest Ophthalmol Vis Sci 56:5048–5059
    • (2015) Invest Ophthalmol Vis Sci , vol.56 , pp. 5048-5059
    • Hanus, J.1    Kolkin, A.2    Chimienti, J.3    Botsay, S.4    Wang, S.5
  • 31
    • 84856111924 scopus 로고    scopus 로고
    • The unfolded protein response: controlling cell fate decisions under ER stress and beyond
    • COI: 1:CAS:528:DC%2BC38XnvVeltQ%3D%3D, PID: 22251901
    • Hetz C (2012) The unfolded protein response: controlling cell fate decisions under ER stress and beyond. Nat Rev Mol Cell Biol 13:89–102
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 89-102
    • Hetz, C.1
  • 32
    • 78049509818 scopus 로고    scopus 로고
    • Gold nanoparticles down regulate VEGF-and IL-1β-induced cell proliferation through Src kinase in Retinal pigment epithelial cells
    • COI: 1:CAS:528:DC%2BC3cXhtlCjsb3L, PID: 20833166
    • Karthikeyan B, Kalishwaralal K, Sheikpranbabu S, Deepak V, Haribalaganesh R, Gurunathan S (2010) Gold nanoparticles down regulate VEGF-and IL-1β-induced cell proliferation through Src kinase in Retinal pigment epithelial cells. Exp Eye Res 91:769–778
    • (2010) Exp Eye Res , vol.91 , pp. 769-778
    • Karthikeyan, B.1    Kalishwaralal, K.2    Sheikpranbabu, S.3    Deepak, V.4    Haribalaganesh, R.5    Gurunathan, S.6
  • 33
    • 84929591024 scopus 로고    scopus 로고
    • EGCG-mediated autophagy flux has a neuroprotection effect via a class III histone deacetylase in primary neuron cells
    • PID: 25991666
    • Lee JH, Moon JH, Kim SW, Jeong JK, Nazim UM, Lee YJ, Seol JW, Park SY (2015) EGCG-mediated autophagy flux has a neuroprotection effect via a class III histone deacetylase in primary neuron cells. Oncotarget 6:9701–9717
    • (2015) Oncotarget , vol.6 , pp. 9701-9717
    • Lee, J.H.1    Moon, J.H.2    Kim, S.W.3    Jeong, J.K.4    Nazim, U.M.5    Lee, Y.J.6    Seol, J.W.7    Park, S.Y.8
  • 34
    • 54249143535 scopus 로고    scopus 로고
    • Cell signaling pathways and iron chelation in the neurorestorative activity of green tea polyphenols: special reference to epigallocatechin gallate (EGCG)
    • COI: 1:CAS:528:DC%2BD1cXht1Cmtr3O, PID: 18953110
    • Mandel SA, Amit T, Kalfon L, Reznichenko L, Weinreb O, Youdim MB (2008) Cell signaling pathways and iron chelation in the neurorestorative activity of green tea polyphenols: special reference to epigallocatechin gallate (EGCG). J Alzheimers Dis 15:211–222
    • (2008) J Alzheimers Dis , vol.15 , pp. 211-222
    • Mandel, S.A.1    Amit, T.2    Kalfon, L.3    Reznichenko, L.4    Weinreb, O.5    Youdim, M.B.6
  • 35
    • 84949638814 scopus 로고    scopus 로고
    • Epigallocatechin gallate attenuates amyloid β-induced inflammation and neurotoxicity in EOC 13.31 microglia
    • Cheng CWJ, Huang HC, Chen WJ, Huang CN, Peng CH, Lin CL (2015) Epigallocatechin gallate attenuates amyloid β-induced inflammation and neurotoxicity in EOC 13.31 microglia. Eur J Pharmacol 770:16–24
    • (2015) Eur J Pharmacol , vol.770 , pp. 16-24
    • Cheng, C.W.J.1    Huang, H.C.2    Chen, W.J.3    Huang, C.N.4    Peng, C.H.5    Lin, C.L.6
  • 36
    • 77953170750 scopus 로고    scopus 로고
    • The retinal pigment epithelium: something more than a constituent of the blood-retinal barrier–implications for the pathogenesis of diabetic retinopathy
    • PID: 20182540
    • Simo R, Villarroel M, Corraliza L, Hernandez C, Garcia-Ramirez M (2010) The retinal pigment epithelium: something more than a constituent of the blood-retinal barrier–implications for the pathogenesis of diabetic retinopathy. J Biomed Biotechnol 2010:190724
    • (2010) J Biomed Biotechnol , vol.2010 , pp. 190724
    • Simo, R.1    Villarroel, M.2    Corraliza, L.3    Hernandez, C.4    Garcia-Ramirez, M.5
  • 38
    • 84881516752 scopus 로고    scopus 로고
    • Proteomic analysis of the aqueous humor in patients with wet age-related macular degeneration
    • COI: 1:CAS:528:DC%2BC3sXntVarsbw%3D, PID: 23418058
    • Yao J, Liu X, Yang Q, Zhuang M, Wang F, Chen X, Hang H, Zhang W, Liu Q (2013) Proteomic analysis of the aqueous humor in patients with wet age-related macular degeneration. Proteomics Clin Appl 7:550–560
    • (2013) Proteomics Clin Appl , vol.7 , pp. 550-560
    • Yao, J.1    Liu, X.2    Yang, Q.3    Zhuang, M.4    Wang, F.5    Chen, X.6    Hang, H.7    Zhang, W.8    Liu, Q.9
  • 39
    • 78149262655 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in age-related macular degeneration: trigger for neovascularization
    • COI: 1:CAS:528:DC%2BC3cXhsVKrt7vK, PID: 20683548
    • Salminen A, Kauppinen A, Hyttinen JM, Toropainen E, Kaarniranta K (2010) Endoplasmic reticulum stress in age-related macular degeneration: trigger for neovascularization. Mol Med 16:535–542
    • (2010) Mol Med , vol.16 , pp. 535-542
    • Salminen, A.1    Kauppinen, A.2    Hyttinen, J.M.3    Toropainen, E.4    Kaarniranta, K.5
  • 41
    • 0035930961 scopus 로고    scopus 로고
    • (–)-Epigallocatechin gallate attenuates β–amyloid induced neurotoxicity in cultured hippocampal neurons
    • COI: 1:CAS:528:DC%2BD38XhtVSmurw%3D, PID: 11811904
    • Choi YT, Jung CH, Lee SR, Bae JH, Baek WK, Suh MH, Park JH, Park CW, Suh SI (2001) (–)-Epigallocatechin gallate attenuates β–amyloid induced neurotoxicity in cultured hippocampal neurons. Life Sci 70:603–614
    • (2001) Life Sci , vol.70 , pp. 603-614
    • Choi, Y.T.1    Jung, C.H.2    Lee, S.R.3    Bae, J.H.4    Baek, W.K.5    Suh, M.H.6    Park, J.H.7    Park, C.W.8    Suh, S.I.9
  • 42
    • 79955659650 scopus 로고    scopus 로고
    • The role and therapeutic potential of prohibitin in disease
    • COI: 1:CAS:528:DC%2BC3MXlvVaisbg%3D, PID: 21296110
    • Theiss AL, Sitaraman SV (2011) The role and therapeutic potential of prohibitin in disease. Biochim Biophys Acta 1813:1137–1143
    • (2011) Biochim Biophys Acta , vol.1813 , pp. 1137-1143
    • Theiss, A.L.1    Sitaraman, S.V.2
  • 43
    • 84857186085 scopus 로고    scopus 로고
    • Prohibitin 1 modulates mitochondrial stress-related autophagy in human colonic epithelial cells
    • COI: 1:CAS:528:DC%2BC38Xjt1Snu7w%3D, PID: 22363587
    • Kathiria AS, Butcher LD, Feagins LA, Souza RF, Boland CR, Theiss AL (2012) Prohibitin 1 modulates mitochondrial stress-related autophagy in human colonic epithelial cells. PLoS One 7:e31231
    • (2012) PLoS One , vol.7
    • Kathiria, A.S.1    Butcher, L.D.2    Feagins, L.A.3    Souza, R.F.4    Boland, C.R.5    Theiss, A.L.6
  • 44
    • 78149272587 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress as a primary pathogenic mechanism leading to age-related macular degeneration
    • PID: 20238041
    • Libby RT, Gould DB (2010) Endoplasmic reticulum stress as a primary pathogenic mechanism leading to age-related macular degeneration. Adv Exp Med Biol 664:403–409
    • (2010) Adv Exp Med Biol , vol.664 , pp. 403-409
    • Libby, R.T.1    Gould, D.B.2
  • 45
    • 84866544628 scopus 로고    scopus 로고
    • The endoplasmic reticulum stress response in aging and age-related diseases
    • Brown MK, Naidoo N (2012) The endoplasmic reticulum stress response in aging and age-related diseases. Front Physiol 16:263
    • (2012) Front Physiol , vol.16 , pp. 263
    • Brown, M.K.1    Naidoo, N.2
  • 48
    • 33645094927 scopus 로고    scopus 로고
    • Targeting multiple signaling pathways by green tea polyphenol (–)-epigallocatechin-3-gallate
    • COI: 1:CAS:528:DC%2BD28XhvV2htrc%3D, PID: 16510563
    • Khan N, Afaq F, Saleem M, Ahmad N, Mukhtar H (2006) Targeting multiple signaling pathways by green tea polyphenol (–)-epigallocatechin-3-gallate. Cancer res 66:2500–2505
    • (2006) Cancer res , vol.66 , pp. 2500-2505
    • Khan, N.1    Afaq, F.2    Saleem, M.3    Ahmad, N.4    Mukhtar, H.5
  • 49
    • 0038121053 scopus 로고    scopus 로고
    • Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions
    • COI: 1:CAS:528:DC%2BD3sXjsl2ltrw%3D, PID: 12587987
    • Higdon JV, Frei B (2003) Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions. Crit Rev Food Sci Nutr 43:89–143
    • (2003) Crit Rev Food Sci Nutr , vol.43 , pp. 89-143
    • Higdon, J.V.1    Frei, B.2
  • 50
    • 1342305497 scopus 로고    scopus 로고
    • Caspase-12 and ER-stress-mediated apoptosis: the story so far
    • COI: 1:CAS:528:DC%2BD2cXisFeksbo%3D, PID: 15033718
    • Szegezdi E, Fitzgerald U, Samali A (2003) Caspase-12 and ER-stress-mediated apoptosis: the story so far. Ann NY Acad Sci 1010: 186–194
    • (2003) Ann NY Acad Sci , vol.1010 , pp. 186-194
    • Szegezdi, E.1    Fitzgerald, U.2    Samali, A.3
  • 51
    • 0034610743 scopus 로고    scopus 로고
    • Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
    • COI: 1:CAS:528:DC%2BD3cXlvVSqsg%3D%3D, PID: 10638761
    • Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, Yuan J (2000) Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β. Nature 403:98–103
    • (2000) Nature , vol.403 , pp. 98-103
    • Nakagawa, T.1    Zhu, H.2    Morishima, N.3    Li, E.4    Xu, J.5    Yankner, B.A.6    Yuan, J.7
  • 52
    • 84986275921 scopus 로고    scopus 로고
    • Cytotoxic effect of ZnS nanoparticles on primary mouse retinal pigment epithelial cells
    • Karthikeyan B, Harini L, Sundar K, Kathiresan T (2016) Cytotoxic effect of ZnS nanoparticles on primary mouse retinal pigment epithelial cells. Artif Cells Nanomed Biotechnol 44:1764–1773
    • (2016) Artif Cells Nanomed Biotechnol , vol.44 , pp. 1764-1773
    • Karthikeyan, B.1    Harini, L.2    Sundar, K.3    Kathiresan, T.4
  • 53
    • 10344253840 scopus 로고    scopus 로고
    • Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death
    • COI: 1:CAS:528:DC%2BD2cXpslKitrY%3D
    • Hu P, Han Z, Couvillon AD, Exton JH (2004) Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death. J BiolChem 279:49420–49429
    • (2004) J BiolChem , vol.279 , pp. 49420-49429
    • Hu, P.1    Han, Z.2    Couvillon, A.D.3    Exton, J.H.4
  • 54
    • 69049096217 scopus 로고    scopus 로고
    • (–)-Epigallocatechin-3-gallate (EGCG) increases the viability of serum-starved A549 cells through its effect on Akt
    • COI: 1:CAS:528:DC%2BC3cXhslKrurw%3D, PID: 19655410
    • Kim MJ, Kim HI, Chung J, Jeong TS, Park HR (2009) (–)-Epigallocatechin-3-gallate (EGCG) increases the viability of serum-starved A549 cells through its effect on Akt. Am J Chin Med 37:723–734
    • (2009) Am J Chin Med , vol.37 , pp. 723-734
    • Kim, M.J.1    Kim, H.I.2    Chung, J.3    Jeong, T.S.4    Park, H.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.