Epigallocatechin gallate attenuates amyloid β-induced inflammation and neurotoxicity in EOC 13.31 microglia

European Journal of Pharmacology

Volumn 770, Issue , 2016, Pages 16-24

  Cheng Chung Wei, James ^a,b,d   Huang, Hsiu Chen ^c   Chen, Wei Jen ^d   Huang, Chien Ning ^d   Peng, Chiung Huei ^e   Lin, Chih Li ^a,d  

^a CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^e HUNGKUANG UNIVERSITY   (Taiwan)

Author keywords

Amyloid ; Epigallocatechin gallate; Microglia; Neuroinflammation; Tumor necrosis factor

Indexed keywords

AMYLOID BETA PROTEIN; EPIGALLOCATECHIN GALLATE; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; CATECHIN; HMOX1 PROTEIN, MOUSE; MEMBRANE PROTEIN; NEUROPROTECTIVE AGENT; NEUROTOXIN; NFE2L2 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVATION; INFLAMMATION; MICROGLIA; MOLECULAR MODEL; MOUSE; NERVE CELL; NEURO 2A NEURONAL CELL; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; CELL LINE; CHEMICALLY INDUCED; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; INTRACELLULAR SPACE; METABOLISM; PATHOLOGY;

AMYLOID BETA-PEPTIDES; ANIMALS; CATECHIN; CELL LINE; GENE EXPRESSION REGULATION; HEME OXYGENASE-1; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTRACELLULAR SPACE; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MICE; MICROGLIA; NEURONS; NEUROPROTECTIVE AGENTS; NEUROTOXINS; NF-E2-RELATED FACTOR 2; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; REACTIVE OXYGEN SPECIES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84949638814     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.11.048     Document Type: Article

References (42)

1. P. Agostinho, R.A. Cunha, and C. Oliveira Neuroinflammation, oxidative stress and the pathogenesis of Alzheimer's disease Curr. Pharm. Des. 16 2010 2766 2778
2. J. Bieschke, J. Russ, R.P. Friedrich, D.E. Ehrnhoefer, H. Wobst, K. Neugebauer, and E.E. Wanker EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity Proc. Natl. Acad. Sci. U.S.A. 107 2010 7710 7715
3. G.J. Broussard, J. Mytar, R.C. Li, and G.J. Klapstein The role of inflammatory processes in Alzheimer's disease Inflammopharmacology 20 2012 109 126
4. D.E. Ehrnhoefer, J. Bieschke, A. Boeddrich, M. Herbst, L. Masino, R. Lurz, S. Engemann, A. Pastore, and E.E. Wanker EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers Nat. Struct. Mol. Biol. 15 2008 558 566
5. S.P. Gabbita, M.K. Srivastava, P. Eslami, M.F. Johnson, N.K. Kobritz, D. Tweedie, N.H. Greig, F.P. Zemlan, S.P. Sharma, and M.E. Harris-White Early intervention with a small molecule inhibitor for tumor necrosis factor-alpha prevents cognitive deficits in a triple transgenic mouse model of Alzheimer's disease J. Neuroinflammation 9 2012 99
6. D. Giulian Microglia and the immune pathology of Alzheimer disease Am. J. Hum. Genet. 65 1999 13 18
7. H. Gonzalez, D. Elgueta, A. Montoya, and R. Pacheco Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases J. Neuroimmunol. 274 2014 1 13
8. A. Hafner, G. Glavan, N. Obermajer, M. Zivin, R. Schliebs, and J. Kos Neuroprotective role of gamma-enolase in microglia in a mouse model of Alzheimer's disease is regulated by cathepsin X Aging Cell. 12 2013 604 614
9. K. Hensley, J. Fedynyshyn, S. Ferrell, R.A. Floyd, B. Gordon, P. Grammas, L. Hamdheydari, M. Mhatre, S. Mou, Q.N. Pye, C. Stewart, M. West, S. West, and K.S. Williamson Message and protein-level elevation of tumor necrosis factor alpha (TNF alpha) and TNF alpha-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis Neurobiol. Dis. 14 2003 74 80
10. K. Herges, J.M. Millward, N. Hentschel, C. Infante-Duarte, O. Aktas, and F. Zipp Neuroprotective effect of combination therapy of glatiramer acetate and epigallocatechin-3-gallate in neuroinflammation Plos one 6 2011 e25456
11. M.M. Hossain, N.L. Banik, and S.K. Ray Survivin knockdown increased anti-cancer effects of (-)-epigallocatechin-3-gallate in human malignant neuroblastoma SK-N-BE2 and SH-SY5Y cells Exp. Cell. Res. 318 2012 1597 1610
12. S.J. Hyung, A.S. DeToma, J.R. Brender, S. Lee, S. Vivekanandan, A. Kochi, J.S. Choi, A. Ramamoorthy, B.T. Ruotolo, and M.H. Lim Insights into antiamyloidogenic properties of the green tea extract (-)-epigallocatechin-3-gallate toward metal-associated amyloid-beta species Proc. Natl. Acad. Sci. United S. Am. 110 2013 3743 3748
13. S. Itagaki, P.L. McGeer, H. Akiyama, S. Zhu, and D. Selkoe Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease J. Neuroimmunol. 24 1989 173 182
14. T.A. Kamalden, D. Ji, and N.N. Osborne Rotenone-induced death of RGC-5 cells is caspase independent, involves the JNK and p38 pathways and is attenuated by specific green tea flavonoids Neurochem. Res. 37 2012 1091 1101
15. B. Kaminska, A. Gozdz, M. Zawadzka, A. Ellert-Miklaszewska, and M. Lipko MAPK Signal Transduction Underlying Brain Inflammation and Gliosis as Therapeutic Target 292 2009 Anatomical record Hoboken, N.J. 1902 1913
16. P.J. Khandelwal, A.M. Herman, and C.E. Moussa Inflammation in the early stages of neurodegenerative pathology J. Neuroimmunol. 238 2011 1 11
17. C.Y. Kim, C. Lee, G.H. Park, and J.H. Jang Neuroprotective effect of epigallocatechin-3-gallate against beta-amyloid-induced oxidative and nitrosative cell death via augmentation of antioxidant defense capacity Arch. Pharmacol. Res. 32 2009 869 881
18. Y.J. Lee, D.Y. Choi, Y.P. Yun, S.B. Han, K.W. Oh, and J.T. Hong Epigallocatechin-3-gallate prevents systemic inflammation-induced memory deficiency and amyloidogenesis via its anti-neuroinflammatory properties J. Nutr. Biochem. 24 2013 298 310
19. E. Li, M. Noda, Y. Doi, B. Parajuli, J. Kawanokuchi, Y. Sonobe, H. Takeuchi, T. Mizuno, and A. Suzumura The neuroprotective effects of milk fat globule-EGF factor 8 against oligomeric amyloid beta toxicity J. Neuroinflammation 9 2012 148
20. J. Li, J.Y. Yang, X.C. Yao, X. Xue, Q.C. Zhang, X.X. Wang, L.L. Ding, and C.F. Wu Oligomeric A beta-induced microglial activation is possibly mediated by NADPH oxidase Neurochem. Res. 38 2013 443 452
21. C.L. Lin, T.F. Chen, M.J. Chiu, T.D. Way, and J.K. Lin Epigallocatechin gallate (EGCG) suppresses beta-amyloid-induced neurotoxicity through inhibiting c-Abl/FE65 nuclear translocation and GSK3 beta activation Neurobiol. Aging 30 2009 81 92
22. L.C. Lin, M.N. Wang, T.Y. Tseng, J.S. Sung, and T.H. Tsai Pharmacokinetics of (-)-epigallocatechin-3-gallate in conscious and freely moving rats and its brain regional distribution J. Agric. Food Chem. 55 2007 1517 1524
23. R.B. Maccioni, L.E. Rojo, J.A. Fernandez, and R.O. Kuljis The Role of Neuroimmunomodulation in Alzheimer's Disease 1153 2009 Annals of the New York Academy of Sciences 240 246
24. S.A. Mandel, T. Amit, O. Weinreb, L. Reznichenko, and M.B. Youdim Simultaneous manipulation of multiple brain targets by green tea catechins: a potential neuroprotective strategy for Alzheimer and Parkinson diseases CNS Neurosci. Ther. 14 2008 352 365
25. K.I. Mosher, and T. Wyss-Coray Microglial dysfunction in brain aging and Alzheimer's disease Biochem. Pharmacol. 88 2014 594 604
26. G. Olmos, and J. Llado Tumor necrosis factor alpha: a link between neuroinflammation and excitotoxicity Mediat. Inflamm. 2014 2014 861231
27. F.L. Palhano, J. Lee, N.P. Grimster, and J.W. Kelly Toward the molecular mechanism(s) by which EGCG treatment remodels mature amyloid fibrils J. Am. Chem. Soc. 135 2013 7503 7510
28. B. Parajuli, Y. Sonobe, H. Horiuchi, H. Takeuchi, T. Mizuno, and A. Suzumura Oligomeric amyloid beta induces IL-1beta processing via production of ROS: implication in Alzheimer's disease Cell. Death Dis. 4 2013 e975
29. S.Y. Park, J.H. Kim, S.J. Lee, and Y. Kim Involvement of PKA and HO-1 signaling in anti-inflammatory effects of surfactin in BV-2 microglial cells Toxicol. Appl. Pharmacol. 268 2013 68 78
30. S.Y. Park, J.H. Kim, S.J. Lee, and Y. Kim Surfactin exhibits neuroprotective effects by inhibiting amyloid beta-mediated microglial activation Neurotoxicology 38 2013 115 123
31. B.L. Queen, and T.O. Tollefsbol Polyphenols and aging Curr. Aging Sci. 3 2010 34 42
32. S. Riegsecker, D. Wiczynski, M.J. Kaplan, and S. Ahmed Potential benefits of green tea polyphenol EGCG in the prevention and treatment of vascular inflammation in rheumatoid arthritis Life Sci. 93 2013 307 312
33. A. Rietveld, and S. Wiseman Antioxidant effects of tea: evidence from human clinical trials J. Nutr. 133 2003 3285S 3292S
34. S.D. Schlatterer, M.A. Tremblay, C.M. Acker, and P. Davies Neuronal c-Abl overexpression leads to neuronal loss and neuroinflammation in the mouse forebrain J. Alzheimer's. Dis.: Jad. 25 2011 119 133
35. J.Q. Shi, W. Shen, J. Chen, B.R. Wang, L.L. Zhong, Y.W. Zhu, H.Q. Zhu, Q.Q. Zhang, Y.D. Zhang, and J. Xu Anti-TNF-alpha reduces amyloid plaques and tau phosphorylation and induces CD11c-positive dendritic-like cell in the APP/PS1 transgenic mouse brains Brain Res. 1368 2011 239 247
36. M. Singh, M. Arseneault, T. Sanderson, V. Murthy, and C. Ramassamy Challenges for research on polyphenols from foods in Alzheimer's disease: bioavailability, metabolism, and cellular and molecular mechanisms J. Agric. food Chem. 56 2008 4855 4873
37. B. Stansley, J. Post, and K. Hensley A comparative review of cell culture systems for the study of microglial biology in Alzheimer's disease J. Neuroinflammation 9 2012 115
38. M.J. Surace, and M.L. Block Targeting microglia-mediated neurotoxicity: the potential of NOX2 inhibitors Cell. Mol. Life Sci.: CMLS 69 2012 2409 2427
39. S. Venneti, C.A. Wiley, and J. Kofler Imaging microglial activation during neuroinflammation and Alzheimer's disease. Journal of neuroimmune pharmacology Off. J. Soc. NeuroImmune Pharmacol. 4 2009 227 243
40. C. Yao, J. Zhang, G. Liu, F. Chen, and Y. Lin Neuroprotection by (-)-epigallocatechin-3-gallate in a rat model of stroke is mediated through inhibition of endoplasmic reticulum stress Mol. Med. Rep. 9 2014 69 76
41. L. Yuan, Y. Wu, X. Ren, Q. Liu, J. Wang, and X. Liu Isoorientin attenuates lipopolysaccharide-induced pro-inflammatory responses through down-regulation of ROS-related MAPK/NF-kappaB signaling pathway in BV-2 microglia Mol. Cell. Biochem. 386 2014 153 165
42. W. Zhou, and W. Hu Anti-neuroinflammatory agents for the treatment of Alzheimer's disease Futur. Med. Chem. 5 2013 1559 1571