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Volumn 19, Issue 9, 2016, Pages 1-9

Fluoxetine inhibits NLRP3 inflammasome activation: Implication in depression

Author keywords

Depression; Double stranded RNA dependent protein kinase; Fluoxetine; NLRP3 inflammasome; Reactive oxygen species

Indexed keywords

CRYOPYRIN; FLUOXETINE; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN KINASE R; REACTIVE OXYGEN METABOLITE;

EID: 84992206890     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1093/ijnp/pyw037     Document Type: Article
Times cited : (103)

References (40)
  • 1
    • 84894258609 scopus 로고    scopus 로고
    • NLRP3 inflammasome: A new target in major depressive disorder
    • Alcocer-Gomez E, Cordero MD (2014) NLRP3 inflammasome: a new target in major depressive disorder. CNS Neurosci Ther 20:294-295.
    • (2014) CNS Neurosci Ther , vol.20 , pp. 294-295
    • Alcocer-Gomez, E.1    Cordero, M.D.2
  • 6
    • 84954068135 scopus 로고    scopus 로고
    • Neuroinflammation and Depression: Microglia activation, extracellular microvesicles and microrna dysregulation
    • Advance online publication
    • Brites D, Fernandes A (2015) Neuroinflammation and Depression: microglia activation, extracellular microvesicles and microrna dysregulation. Front Cell Neurosci. Advance online publication. doi: 10.3389/fncel.2015.00476.
    • (2015) Front Cell Neurosci
    • Brites, D.1    Fernandes, A.2
  • 7
    • 84903897249 scopus 로고    scopus 로고
    • Inflammasomes: Molecular regulation and implications for metabolic and cognitive diseases
    • Choi AJ, Ryter SW (2014) Inflammasomes: molecular regulation and implications for metabolic and cognitive diseases. Mol Cells 37:441-448.
    • (2014) Mol Cells , vol.37 , pp. 441-448
    • Choi, A.J.1    Ryter, S.W.2
  • 9
    • 79851507642 scopus 로고    scopus 로고
    • Incidence of major depressive episode correlates with elevation of substate region of residence
    • DelMastro K, Hellem T, Kim N, Kondo D, Sung YH, Renshaw PF (2015) Incidence of major depressive episode correlates with elevation of substate region of residence. J Affect Disord 129:376-379.
    • (2015) J Affect Disord , vol.129 , pp. 376-379
    • DelMastro, K.1    Hellem, T.2    Kim, N.3    Kondo, D.4    Sung, Y.H.5    Renshaw, P.F.6
  • 10
    • 84944892881 scopus 로고    scopus 로고
    • Geraniol produces antidepressant-like effects in a chronic unpredictable mild stress mice model
    • Deng XY, Xue JS, Li HY, Ma ZQ, Fu Q, Qu R, Ma SP (2015) Geraniol produces antidepressant-like effects in a chronic unpredictable mild stress mice model. Physiol Behav 152:264-271.
    • (2015) Physiol Behav , vol.152 , pp. 264-271
    • Deng, X.Y.1    Xue, J.S.2    Li, H.Y.3    Ma, Z.Q.4    Fu, Q.5    Qu, R.6    Ma, S.P.7
  • 11
    • 34248392684 scopus 로고    scopus 로고
    • Microglial activation and its implications in thebrain diseases
    • Dheen ST, Kaur C, Ling EA (2007) Microglial activation and its implications in thebrain diseases. Curr Med Chem 14: 1189-1197.
    • (2007) Curr Med Chem , vol.14 , pp. 1189-1197
    • Dheen, S.T.1    Kaur, C.2    Ling, E.A.3
  • 12
    • 84876350807 scopus 로고    scopus 로고
    • The therapeutic potential of modifying inflammasomes and NOD-like receptors
    • Di Virgilio F (2014) The therapeutic potential of modifying inflammasomes and NOD-like receptors. Pharmacol Rev 65:872-905.
    • (2014) Pharmacol Rev , vol.65 , pp. 872-905
    • Di Virgilio, F.1
  • 13
    • 84906345413 scopus 로고    scopus 로고
    • Beta-Arrestin 2 mediates the antiinflammatory effects of fluoxetine in lipopolysaccharidestimulated microglial cells
    • Du RW, Du RH, Bu WG (2014) beta-Arrestin 2 mediates the antiinflammatory effects of fluoxetine in lipopolysaccharidestimulated microglial cells. J Neuroimmune Pharmacol 9:582-590.
    • (2014) J Neuroimmune Pharmacol , vol.9 , pp. 582-590
    • Du, R.W.1    Du, R.H.2    Bu, W.G.3
  • 14
    • 84927724336 scopus 로고    scopus 로고
    • Initiation and perpetuation of NLRP3 inflammasome activation and assembly
    • Elliott EI, Sutterwala FS (2015) Initiation and perpetuation of NLRP3 inflammasome activation and assembly. Immunol Rev 265:35-52.
    • (2015) Immunol Rev , vol.265 , pp. 35-52
    • Elliott, E.I.1    Sutterwala, F.S.2
  • 15
    • 84858677223 scopus 로고    scopus 로고
    • Sensing and reacting to microbes through the inflammasomes
    • Franchi L, Munoz-Planillo R, Nunez G (2014) Sensing and reacting to microbes through the inflammasomes. Nat Immunol 13:325-332.
    • (2014) Nat Immunol , vol.13 , pp. 325-332
    • Franchi, L.1    Munoz-Planillo, R.2    Nunez, G.3
  • 16
    • 0033971010 scopus 로고    scopus 로고
    • Factors affecting prescribing of the newer antidepressants
    • Garrison GD, Levin GM (2000) Factors affecting prescribing of the newer antidepressants. Ann Pharmacother 34:10-14.
    • (2000) Ann Pharmacother , vol.34 , pp. 10-14
    • Garrison, G.D.1    Levin, G.M.2
  • 17
    • 84874347880 scopus 로고    scopus 로고
    • Neuroregenerative mechanisms of allopregnanolone in Alzheimer's disease
    • Advance online publication
    • Irwin RW, Wang JM, Chen S, Brinton RD (2012) Neuroregenerative mechanisms of allopregnanolone in Alzheimer's disease. Front Endocrinol. Advance online publication. doi: 10.3389/ fendo.2011.00117.
    • (2012) Front Endocrinol
    • Irwin, R.W.1    Wang, J.M.2    Chen, S.3    Brinton, R.D.4
  • 19
    • 84925374812 scopus 로고    scopus 로고
    • Mechanisms and potential therapeutic applications of microglial activation after brain injury
    • Kim JY, Kim N, Yenari MA (2015) Mechanisms and potential therapeutic applications of microglial activation after brain injury. CNS Neurosci Ther 21:309-319.
    • (2015) CNS Neurosci Ther , vol.21 , pp. 309-319
    • Kim, J.Y.1    Kim, N.2    Yenari, M.A.3
  • 20
    • 84957309462 scopus 로고    scopus 로고
    • Suppression of NLRP3 inflammasome by gamma-tocotrienol ameliorates type 2 diabetes
    • Kim Y, Wang W, Okla M, Kang I, Moreau R, Chung S (2016) Suppression of NLRP3 inflammasome by gamma-tocotrienol ameliorates type 2 diabetes. J Lipid Res 57:66-76.
    • (2016) J Lipid Res , vol.57 , pp. 66-76
    • Kim, Y.1    Wang, W.2    Okla, M.3    Kang, I.4    Moreau, R.5    Chung, S.6
  • 21
    • 84869504451 scopus 로고    scopus 로고
    • Inflammasomes and their roles in health and disease
    • Lamkanfi M, Dixit VM (2014) Inflammasomes and their roles in health and disease. Annu Rev Cell Dev Biol 28:137-161.
    • (2014) Annu Rev Cell Dev Biol , vol.28 , pp. 137-161
    • Lamkanfi, M.1    Dixit, V.M.2
  • 22
    • 84943385476 scopus 로고    scopus 로고
    • Apigenin ameliorates chronic mild stress-induced depressive behavior by inhibiting interleukin-1beta production and NLRP3 inflammasome activation in the rat brain
    • Li R, Wang X, Qin T, Qu R, Ma S (2016) Apigenin ameliorates chronic mild stress-induced depressive behavior by inhibiting interleukin-1beta production and NLRP3 inflammasome activation in the rat brain. Behav Brain Res 296:318-325.
    • (2016) Behav Brain Res , vol.296 , pp. 318-325
    • Li, R.1    Wang, X.2    Qin, T.3    Qu, R.4    Ma, S.5
  • 23
    • 84925715644 scopus 로고    scopus 로고
    • Icariin exerts an antidepressant effect in an unpredictable chronic mild stress model of depression in rats and is associated with the regulation of hippocampal neuroinflammation
    • Liu B, Xu C, Wu X, Liu F, Du Y, Sun J, Tao J, Dong J (2015) Icariin exerts an antidepressant effect in an unpredictable chronic mild stress model of depression in rats and is associated with the regulation of hippocampal neuroinflammation. Neuroscience 294:193-205.
    • (2015) Neuroscience , vol.294 , pp. 193-205
    • Liu, B.1    Xu, C.2    Wu, X.3    Liu, F.4    Du, Y.5    Sun, J.6    Tao, J.7    Dong, J.8
  • 24
    • 79959953811 scopus 로고    scopus 로고
    • Anti-inflammatory effects of fluoxetine in lipopolysaccharide(LPS)-stimulated microglial cells
    • Liu D, Wang Z, Liu S, Wang F, Zhao S, Hao A (2013) Anti-inflammatory effects of fluoxetine in lipopolysaccharide(LPS)-stimulated microglial cells. Neuropharmacology 61:592-599.
    • (2013) Neuropharmacology , vol.61 , pp. 592-599
    • Liu, D.1    Wang, Z.2    Liu, S.3    Wang, F.4    Zhao, S.5    Hao, A.6
  • 26
    • 84904877341 scopus 로고    scopus 로고
    • Iptakalim confers an antidepressant effect in a chronic mild stress model of depression through regulating neuro-inflammation and neurogenesis
    • Lu M, Yang JZ, Geng F, Ding JH, Hu G (2014) Iptakalim confers an antidepressant effect in a chronic mild stress model of depression through regulating neuro-inflammation and neurogenesis. Int J Neuropsychopharmacol 17:1501-1510.
    • (2014) Int J Neuropsychopharmacol , vol.17 , pp. 1501-1510
    • Lu, M.1    Yang, J.Z.2    Geng, F.3    Ding, J.H.4    Hu, G.5
  • 27
    • 77749304032 scopus 로고    scopus 로고
    • Signaling by ROS drives inflammasome activation
    • Martinon F (2015) Signaling by ROS drives inflammasome activation. Eur J Immunol 40:616-619.
    • (2015) Eur J Immunol , vol.40 , pp. 616-619
    • Martinon, F.1
  • 28
    • 32944468985 scopus 로고    scopus 로고
    • Goutassociated uric acid crystals activate the NALP3 inflammasome
    • Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J (2006) Goutassociated uric acid crystals activate the NALP3 inflammasome. Nature 440:237-241.
    • (2006) Nature , vol.440 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 29
    • 0031660034 scopus 로고    scopus 로고
    • Efficacy and safety of the selective serotonin reuptake inhibitors in treating depression in elderly patients
    • Montgomery SA (1998) Efficacy and safety of the selective serotonin reuptake inhibitors in treating depression in elderly patients. Int Clin Psychopharmacol, 13:S49-54.
    • (1998) Int Clin Psychopharmacol , vol.13 , pp. S49-S54
    • Montgomery, S.A.1
  • 30
    • 84924052001 scopus 로고    scopus 로고
    • Microglial NLRP3 inflammasome activation mediates IL-1beta-related inflammation in prefrontal cortex of depressive rats
    • Pan Y, Chen XY, Zhang QY, Kong LD (2014) Microglial NLRP3 inflammasome activation mediates IL-1beta-related inflammation in prefrontal cortex of depressive rats. Brain Behav Immun 41:90-100.
    • (2014) Brain Behav Immun , vol.41 , pp. 90-100
    • Pan, Y.1    Chen, X.Y.2    Zhang, Q.Y.3    Kong, L.D.4
  • 31
    • 56149097715 scopus 로고    scopus 로고
    • Oxidative stress induces PKRdependent apoptosis via IFN-gamma activation signaling in Jurkat T cells
    • Pyo CW, Lee SH, Choi SY (2008) Oxidative stress induces PKRdependent apoptosis via IFN-gamma activation signaling in Jurkat T cells. Biochem Biophys Res Commun 377:1001-1006.
    • (2008) Biochem Biophys Res Commun , vol.377 , pp. 1001-1006
    • Pyo, C.W.1    Lee, S.H.2    Choi, S.Y.3
  • 33
    • 84922343846 scopus 로고    scopus 로고
    • Peripheral and central effects of repeated social defeat stress: Monocyte trafficking, microglial activation, and anxiety
    • Reader BF, Jarrett BL, McKim DB, Wohleb ES, Godbout JP, Sheridan JF (2015) Peripheral and central effects of repeated social defeat stress: monocyte trafficking, microglial activation, and anxiety. Neuroscience 289:429-442.
    • (2015) Neuroscience , vol.289 , pp. 429-442
    • Reader, B.F.1    Jarrett, B.L.2    McKim, D.B.3    Wohleb, E.S.4    Godbout, J.P.5    Sheridan, J.F.6
  • 34
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder K, Tschopp J (2014) The inflammasomes. Cell 140: 821-832.
    • (2014) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 35
    • 84949742300 scopus 로고    scopus 로고
    • NLRP3 inflammasome and its inhibitors: A review
    • Advance online publication
    • Shao BZ, Xu ZQ, Han BZ, Su DF, Liu C (2015) NLRP3 inflammasome and its inhibitors: a review. Front Pharmacol. Advance online publication. doi: 10.3389/fphar.2015.00262.
    • (2015) Front Pharmacol
    • Shao, B.Z.1    Xu, Z.Q.2    Han, B.Z.3    Su, D.F.4    Liu, C.5
  • 36
    • 84928969607 scopus 로고    scopus 로고
    • L-Menthone confers antidepressant-like effects in an unpredictable chronic mild stress mouse model via NLRP3 inflammasome-mediated inflammatory cytokines and central neurotransmitters
    • Xue J, Li H, Deng X, Ma Z, Fu Q, Ma S (2015) L-Menthone confers antidepressant-like effects in an unpredictable chronic mild stress mouse model via NLRP3 inflammasome-mediated inflammatory cytokines and central neurotransmitters. Pharmacol Biochem Behav 134:42-48.
    • (2015) Pharmacol Biochem Behav , vol.134 , pp. 42-48
    • Xue, J.1    Li, H.2    Deng, X.3    Ma, Z.4    Fu, Q.5    Ma, S.6
  • 37
    • 84865803744 scopus 로고    scopus 로고
    • Iptakalim enhances adult mouse hippocampal neurogenesis via opening Kir6.1-composed K-ATP channels expressed in neural stem cells
    • Yang JZ, Huang X, Zhao FF, Xu Q, Hu G (2013) Iptakalim enhances adult mouse hippocampal neurogenesis via opening Kir6.1-composed K-ATP channels expressed in neural stem cells. CNS Neurosci Ther 18:737-744.
    • (2013) CNS Neurosci Ther , vol.18 , pp. 737-744
    • Yang, J.Z.1    Huang, X.2    Zhao, F.F.3    Xu, Q.4    Hu, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.