The Nlrp3 Inflammasome Does Not Regulate Alloimmunization to Transfused Red Blood Cells in Mice

EBioMedicine

Volumn 9, Issue , 2016, Pages 77-86

  Gibb, David R ^a   Calabro, Samuele ^a   Liu, Dong ^a   Tormey, Christopher A ^a   Spitalnik, Steven L ^b   Zimring, James C ^c,d   Hendrickson, Jeanne E ^a   Hod, Eldad A ^b   Eisenbarth, Stephanie C ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Medicine   (United States)

^c Bloodworks NW Research Institute ^*  (United States)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Alloimmunization; Conventional dendritic cells (cDCs); Inflammasome; NLRP3; Red blood cell (RBC) storage

Indexed keywords

ALLOANTIBODY; CD86 ANTIGEN; CRYOPYRIN; HEME; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCYTE CHEMOTACTIC PROTEIN 1; PATHOGEN ASSOCIATED MOLECULAR PATTERN; TUMOR NECROSIS FACTOR; ALLOANTIGEN; BLOOD GROUP ANTIGEN; CYTOKINE;

ALLOIMMUNITY; ANIMAL EXPERIMENT; ANTIBODY DETECTION; ANTIBODY RESPONSE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE TRANSFUSION; FLOW CYTOMETRY; GENE DELETION; IMMUNOREGULATION; INFLAMMATION; INNATE IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; ADVERSE EFFECTS; ANIMAL; ANIMAL MODEL; BIOLOGICAL MODEL; ERYTHROCYTE; GENETICS; IMMUNOLOGY; IMMUNOMODULATION; IMMUNOPHENOTYPING; KNOCKOUT MOUSE; METABOLISM; PHENOTYPE;

ANIMALS; BLOOD GROUP ANTIGENS; CYTOKINES; DENDRITIC CELLS; ERYTHROCYTE TRANSFUSION; ERYTHROCYTES; IMMUNOMODULATION; IMMUNOPHENOTYPING; INFLAMMASOMES; INFLAMMATION; ISOANTIBODIES; ISOANTIGENS; MICE; MICE, KNOCKOUT; MODELS, ANIMAL; MODELS, BIOLOGICAL; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; PHENOTYPE;

EID: 84991666190     PISSN: None     EISSN: 23523964     Source Type: Journal    
DOI: 10.1016/j.ebiom.2016.06.008     Document Type: Article

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