FOXO/DAF-16 Activation Slows Down Turnover of the Majority of Proteins in C. elegans

Cell Reports

Volumn 16, Issue 11, 2016, Pages 3028-3040

  Dhondt, Ineke ^a   Petyuk, Vladislav A ^b   Cai, Huaihan ^a   Vandemeulebroucke, Lieselot ^a   Vierstraete, Andy ^a   Smith, Richard D ^b   Depuydt, Geert ^a,c   Braeckman, Bart P ^a  

^a GHENT UNIVERSITY   (Belgium)

^b PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

15N metabolic labeling; aging; Caenorhabditis elegans; daf 2 mutant; FOXO DAF 16; protein turnover

Indexed keywords

MITOCHONDRIAL PROTEIN; NITROGEN; TRANSCRIPTION FACTOR DAF 16; TRANSCRIPTION FACTOR FOXO; CAENORHABDITIS ELEGANS PROTEIN; CYTOSKELETON PROTEIN; DAF-16 PROTEIN, C ELEGANS; FORKHEAD TRANSCRIPTION FACTOR; MUSCLE PROTEIN;

ADULT; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; CYTOSKELETON; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ISOTOPE LABELING; LIFESPAN; MASS SPECTROMETRY; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN HALF LIFE; PROTEIN METABOLISM; PROTEIN SYNTHESIS; ANIMAL; CELL FRACTIONATION; HALF LIFE TIME; INTRACELLULAR MEMBRANE; LYSOSOME; METABOLISM; MITOCHONDRION; PHYSIOLOGICAL STRESS; PROTEOMICS; REPRODUCIBILITY;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CYTOSKELETAL PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; HALF-LIFE; INTRACELLULAR MEMBRANES; ISOTOPE LABELING; LYSOSOMES; MITOCHONDRIA; MUSCLE PROTEINS; PROTEIN BIOSYNTHESIS; PROTEOMICS; REPRODUCIBILITY OF RESULTS; STRESS, PHYSIOLOGICAL; SUBCELLULAR FRACTIONS;

EID: 84991650769     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.07.088     Document Type: Article

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