메뉴 건너뛰기




Volumn 20, Issue 1, 2016, Pages

Antifibrotic therapies to control cardiac fibrosis

Author keywords

Antifibrotic therapy; Cardiac fibroblasts; Cardiac fibrosis; Myocardial infarction; Myofibroblasts

Indexed keywords


EID: 84991342307     PISSN: None     EISSN: 20557124     Source Type: Journal    
DOI: 10.1186/s40824-016-0060-8     Document Type: Review
Times cited : (110)

References (136)
  • 1
    • 84878183269 scopus 로고    scopus 로고
    • The extracellular matrix modulates fibroblast phenotype and function in the infarcted myocardium
    • Dobaczewski M, de Haan JJ, Frangogiannis NG. The extracellular matrix modulates fibroblast phenotype and function in the infarcted myocardium. J Cardiovasc Transl Res. 2012;5:837-47.
    • (2012) J Cardiovasc Transl Res. , vol.5 , pp. 837-847
    • Dobaczewski, M.1    de Haan, J.J.2    Frangogiannis, N.G.3
  • 4
    • 83555166013 scopus 로고    scopus 로고
    • Progressive induction of left ventricular pressure overload in a large animal model elicits myocardial remodeling and a unique matrix signature
    • Yarbrough WM, Mukherjee R, Stroud RE, Rivers WT, Oelsen JM, Dixon JA, et al. Progressive induction of left ventricular pressure overload in a large animal model elicits myocardial remodeling and a unique matrix signature. J Thorac Cardiovasc Surg. 2012;143:215-23.
    • (2012) J Thorac Cardiovasc Surg. , vol.143 , pp. 215-223
    • Yarbrough, W.M.1    Mukherjee, R.2    Stroud, R.E.3    Rivers, W.T.4    Oelsen, J.M.5    Dixon, J.A.6
  • 6
    • 1042292003 scopus 로고    scopus 로고
    • The dynamic interaction between matrix metalloproteinase activity and adverse myocardial remodeling
    • Janicki JS, Brower GL, Gardner JD, Chancey AL, Stewart Jr JA. The dynamic interaction between matrix metalloproteinase activity and adverse myocardial remodeling. Heart Fail Rev. 2004;9:33-42.
    • (2004) Heart Fail Rev. , vol.9 , pp. 33-42
    • Janicki, J.S.1    Brower, G.L.2    Gardner, J.D.3    Chancey, A.L.4    Stewart, J.A.5
  • 7
    • 84874404425 scopus 로고    scopus 로고
    • Membrane-associated matrix proteolysis and heart failure
    • Spinale FG, Janicki JS, Zile MR. Membrane-associated matrix proteolysis and heart failure. Circ Res. 2013;112:195-208.
    • (2013) Circ Res. , vol.112 , pp. 195-208
    • Spinale, F.G.1    Janicki, J.S.2    Zile, M.R.3
  • 8
    • 1042292006 scopus 로고    scopus 로고
    • Matrix metalloproteinases: pathways of induction by bioactive molecules
    • Tsuruda T, Costello-Boerrigter LC, Burnett Jr JC. Matrix metalloproteinases: pathways of induction by bioactive molecules. Heart Fail Rev. 2004;9:53-61.
    • (2004) Heart Fail Rev. , vol.9 , pp. 53-61
    • Tsuruda, T.1    Costello-Boerrigter, L.C.2    Burnett, J.C.3
  • 9
    • 78751507979 scopus 로고    scopus 로고
    • Molecular mechanisms that control interstitial fibrosis in the pressure-overloaded heart
    • Creemers EE, Pinto YM. Molecular mechanisms that control interstitial fibrosis in the pressure-overloaded heart. Cardiovasc Res. 2011;89:265-72.
    • (2011) Cardiovasc Res. , vol.89 , pp. 265-272
    • Creemers, E.E.1    Pinto, Y.M.2
  • 10
    • 84930741570 scopus 로고    scopus 로고
    • Getting to the heart of the matter: new insights into cardiac fibrosis
    • Leask A. Getting to the heart of the matter: new insights into cardiac fibrosis. Circ Res. 2015;116:1269-76.
    • (2015) Circ Res. , vol.116 , pp. 1269-1276
    • Leask, A.1
  • 11
    • 0019127308 scopus 로고
    • Study of non-muscle cells of the adult mammalian heart: a fine structural analysis and distribution
    • Nag AC. Study of non-muscle cells of the adult mammalian heart: a fine structural analysis and distribution. Cytobios. 1980;28:41-61.
    • (1980) Cytobios. , vol.28 , pp. 41-61
    • Nag, A.C.1
  • 12
    • 84899081318 scopus 로고    scopus 로고
    • Fibroblasts in myocardial infarction: a role in inflammation and repair
    • Shinde AV, Frangogiannis NG. Fibroblasts in myocardial infarction: a role in inflammation and repair. J Mol Cell Cardiol. 2014;70:74-82.
    • (2014) J Mol Cell Cardiol. , vol.70 , pp. 74-82
    • Shinde, A.V.1    Frangogiannis, N.G.2
  • 13
    • 0028173386 scopus 로고
    • The alpha-smooth muscle actin-positive cells in healing human myocardial scars
    • Willems IE, Havenith MG, De Mey JG, Daemen MJ. The alpha-smooth muscle actin-positive cells in healing human myocardial scars. Am J Pathol. 1994;145:868-75.
    • (1994) Am J Pathol. , vol.145 , pp. 868-875
    • Willems, I.E.1    Havenith, M.G.2    De Mey, J.G.3    Daemen, M.J.4
  • 14
    • 0028535872 scopus 로고
    • Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair
    • Bucala R, Spiegel LA, Chesney J, Hogan M, Cerami A. Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair. Mol Med. 1994;1:71-81.
    • (1994) Mol Med. , vol.1 , pp. 71-81
    • Bucala, R.1    Spiegel, L.A.2    Chesney, J.3    Hogan, M.4    Cerami, A.5
  • 15
    • 0030975153 scopus 로고    scopus 로고
    • Peripheral blood fibrocytes: novel fibroblast-like cells that present antigen and mediate tissue repair
    • Chesney J, Bucala R. Peripheral blood fibrocytes: novel fibroblast-like cells that present antigen and mediate tissue repair. Biochem Soc Trans. 1997;25:520-4.
    • (1997) Biochem Soc Trans. , vol.25 , pp. 520-524
    • Chesney, J.1    Bucala, R.2
  • 16
    • 13544263380 scopus 로고    scopus 로고
    • Fibrocytes contribute to the myofibroblast population in wounded skin and originate from the bone marrow
    • Mori L, Bellini A, Stacey MA, Schmidt M, Mattoli S. Fibrocytes contribute to the myofibroblast population in wounded skin and originate from the bone marrow. Exp Cell Res. 2005;304:81-90.
    • (2005) Exp Cell Res. , vol.304 , pp. 81-90
    • Mori, L.1    Bellini, A.2    Stacey, M.A.3    Schmidt, M.4    Mattoli, S.5
  • 17
    • 0031053724 scopus 로고    scopus 로고
    • Inverse correlation between CD34 expression and proline-4-hydroxylase immunoreactivity on spindle cells noted in hypertrophic scars and keloids
    • Aiba S, Tagami H. Inverse correlation between CD34 expression and proline-4-hydroxylase immunoreactivity on spindle cells noted in hypertrophic scars and keloids. J Cutan Pathol. 1997;24:65-9.
    • (1997) J Cutan Pathol. , vol.24 , pp. 65-69
    • Aiba, S.1    Tagami, H.2
  • 18
    • 34347228684 scopus 로고    scopus 로고
    • Endothelin-1 induces alveolar epithelialmesenchymal transition through endothelin type A receptor-mediated production of TGF-beta1
    • Jain R, Shaul PW, Borok Z, Willis BC. Endothelin-1 induces alveolar epithelialmesenchymal transition through endothelin type A receptor-mediated production of TGF-beta1. Am J Respir Cell Mol Biol. 2007;37:38-47.
    • (2007) Am J Respir Cell Mol Biol. , vol.37 , pp. 38-47
    • Jain, R.1    Shaul, P.W.2    Borok, Z.3    Willis, B.C.4
  • 19
    • 0346724511 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and its implications for fibrosis
    • Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest. 2003;112:1776-84.
    • (2003) J Clin Invest. , vol.112 , pp. 1776-1784
    • Kalluri, R.1    Neilson, E.G.2
  • 20
    • 73949090678 scopus 로고    scopus 로고
    • TGF-beta1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1beta but not abrogated by corticosteroids
    • Doerner AM, Zuraw BL. TGF-beta1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1beta but not abrogated by corticosteroids. Respir Res. 2009;10:1465-9921.
    • (2009) Respir Res. , vol.10 , pp. 1465-9921
    • Doerner, A.M.1    Zuraw, B.L.2
  • 21
    • 76749153383 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha enhances both epithelial-mesenchymal transition and cell contraction induced in A549 human alveolar epithelial cells by transforming growth factor-beta1
    • Yamauchi Y, Kohyama T, Takizawa H, Kamitani S, Desaki M, Takami K, et al. Tumor necrosis factor-alpha enhances both epithelial-mesenchymal transition and cell contraction induced in A549 human alveolar epithelial cells by transforming growth factor-beta1. Exp Lung Res. 2010;36:12-24.
    • (2010) Exp Lung Res. , vol.36 , pp. 12-24
    • Yamauchi, Y.1    Kohyama, T.2    Takizawa, H.3    Kamitani, S.4    Desaki, M.5    Takami, K.6
  • 23
    • 84875232512 scopus 로고    scopus 로고
    • IL-1beta and TGFbeta2 synergistically induce endothelial to mesenchymal transition in an NFkappaB-dependent manner
    • Maleszewska M, Moonen JR, Huijkman N, van de Sluis B, Krenning G, Harmsen MC. IL-1beta and TGFbeta2 synergistically induce endothelial to mesenchymal transition in an NFkappaB-dependent manner. Immunobiology. 2013;218:443-54.
    • (2013) Immunobiology. , vol.218 , pp. 443-454
    • Maleszewska, M.1    Moonen, J.R.2    Huijkman, N.3    van de Sluis, B.4    Krenning, G.5    Harmsen, M.C.6
  • 24
    • 84863362767 scopus 로고    scopus 로고
    • Role of tumor necrosis factor alpha in endothelial-mesenchymal transition in vitro
    • Dai H, Huang H, Wang SL, Xu X, Jian Y, Cui WH, et al. Role of tumor necrosis factor alpha in endothelial-mesenchymal transition in vitro. Zhonghua Shao Shang Za Zhi. 2012;28:19-24.
    • (2012) Zhonghua Shao Shang Za Zhi. , vol.28 , pp. 19-24
    • Dai, H.1    Huang, H.2    Wang, S.L.3    Xu, X.4    Jian, Y.5    Cui, W.H.6
  • 25
    • 77951784020 scopus 로고    scopus 로고
    • Targeted inhibition of activin receptor-like kinase 5 signaling attenuates cardiac dysfunction following myocardial infarction
    • Tan SM, Zhang Y, Connelly KA, Gilbert RE, Kelly DJ. Targeted inhibition of activin receptor-like kinase 5 signaling attenuates cardiac dysfunction following myocardial infarction. Am J Physiol Heart Circ Physiol. 2010;298: H1415-25.
    • (2010) Am J Physiol Heart Circ Physiol. , vol.298 , pp. H1415-H1425
    • Tan, S.M.1    Zhang, Y.2    Connelly, K.A.3    Gilbert, R.E.4    Kelly, D.J.5
  • 26
    • 0032142834 scopus 로고    scopus 로고
    • Angiotensin II, transforming growth factor-beta1 and repair in the infarcted heart
    • Sun Y, Zhang JQ, Zhang J, Ramires FJ. Angiotensin II, transforming growth factor-beta1 and repair in the infarcted heart. J Mol Cell Cardiol. 1998;30: 1559-69.
    • (1998) J Mol Cell Cardiol. , vol.30 , pp. 1559-1569
    • Sun, Y.1    Zhang, J.Q.2    Zhang, J.3    Ramires, F.J.4
  • 27
    • 0034806667 scopus 로고    scopus 로고
    • Effects of combination of angiotensin-converting enzyme inhibitor and angiotensin receptor antagonist on inflammatory cellular infiltration and myocardial interstitial fibrosis after acute myocardial infarction
    • Yu CM, Tipoe GL, Wing-Hon Lai K, Lau CP. Effects of combination of angiotensin-converting enzyme inhibitor and angiotensin receptor antagonist on inflammatory cellular infiltration and myocardial interstitial fibrosis after acute myocardial infarction. J Am Coll Cardiol. 2001;38:1207-15.
    • (2001) J Am Coll Cardiol. , vol.38 , pp. 1207-1215
    • Yu, C.M.1    Tipoe, G.L.2    Wing-Hon Lai, K.3    Lau, C.P.4
  • 28
    • 0031194295 scopus 로고    scopus 로고
    • Angiotensin II stimulated expression of transforming growth factor-beta1 in cardiac fibroblasts and myofibroblasts
    • Campbell SE, Katwa LC. Angiotensin II stimulated expression of transforming growth factor-beta1 in cardiac fibroblasts and myofibroblasts. J Mol Cell Cardiol. 1997;29:1947-58.
    • (1997) J Mol Cell Cardiol. , vol.29 , pp. 1947-1958
    • Campbell, S.E.1    Katwa, L.C.2
  • 29
    • 60949097622 scopus 로고    scopus 로고
    • Angiotensin II increases collagen I expression via transforming growth factor-beta1 and extracellular signalregulated kinase in cardiac fibroblasts
    • Gao X, He X, Luo B, Peng L, Lin J, Zuo Z. Angiotensin II increases collagen I expression via transforming growth factor-beta1 and extracellular signalregulated kinase in cardiac fibroblasts. Eur J Pharmacol. 2009;606:115-20.
    • (2009) Eur J Pharmacol. , vol.606 , pp. 115-120
    • Gao, X.1    He, X.2    Luo, B.3    Peng, L.4    Lin, J.5    Zuo, Z.6
  • 30
    • 84860524460 scopus 로고    scopus 로고
    • Macrophage-stimulated cardiac fibroblast production of IL-6 is essential for TGF beta/Smad activation and cardiac fibrosis induced by angiotensin II
    • Ma F, Li Y, Jia L, Han Y, Cheng J, Li H, et al. Macrophage-stimulated cardiac fibroblast production of IL-6 is essential for TGF beta/Smad activation and cardiac fibrosis induced by angiotensin II. PLoS One. 2012;7:e35144.
    • (2012) PLoS One. , vol.7
    • Ma, F.1    Li, Y.2    Jia, L.3    Han, Y.4    Cheng, J.5    Li, H.6
  • 31
    • 33847727030 scopus 로고    scopus 로고
    • Chronic blockade of angiotensin II AT1-receptors increased cell-to-cell communication, reduced fibrosis and improved impulse propagation in the failing heart
    • De Mello WC, Specht P. Chronic blockade of angiotensin II AT1-receptors increased cell-to-cell communication, reduced fibrosis and improved impulse propagation in the failing heart. J Renin Angiotensin Aldosterone Syst. 2006;7:201-5.
    • (2006) J Renin Angiotensin Aldosterone Syst. , vol.7 , pp. 201-205
    • De Mello, W.C.1    Specht, P.2
  • 32
    • 33644871478 scopus 로고    scopus 로고
    • Impact of the angiotensin II receptor antagonist, losartan, on myocardial fibrosis in patients with end-stage renal disease: assessment by ultrasonic integrated backscatter and biochemical markers
    • Shibasaki Y, Nishiue T, Masaki H, Tamura K, Matsumoto N, Mori Y, et al. Impact of the angiotensin II receptor antagonist, losartan, on myocardial fibrosis in patients with end-stage renal disease: assessment by ultrasonic integrated backscatter and biochemical markers. Hypertens Res. 2005; 28:787-95.
    • (2005) Hypertens Res. , vol.28 , pp. 787-795
    • Shibasaki, Y.1    Nishiue, T.2    Masaki, H.3    Tamura, K.4    Matsumoto, N.5    Mori, Y.6
  • 33
    • 0035152071 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor deficiency alters matrix metalloproteinase 13/tissue inhibitor of metalloproteinase 1 expression in murine silicosis
    • Ortiz LA, Lasky J, Gozal E, Ruiz V, Lungarella G, Cavarra E, et al. Tumor necrosis factor receptor deficiency alters matrix metalloproteinase 13/tissue inhibitor of metalloproteinase 1 expression in murine silicosis. Am J Respir Crit Care Med. 2001;163:244-52.
    • (2001) Am J Respir Crit Care Med. , vol.163 , pp. 244-252
    • Ortiz, L.A.1    Lasky, J.2    Gozal, E.3    Ruiz, V.4    Lungarella, G.5    Cavarra, E.6
  • 34
    • 33748515649 scopus 로고    scopus 로고
    • Inhibition of p38 mitogen-activated protein kinase attenuates left ventricular dysfunction by mediating pro-inflammatory cardiac cytokine levels in a mouse model of diabetes mellitus
    • Westermann D, Rutschow S, Van Linthout S, Linderer A, Bucker-Gartner C, Sobirey M, et al. Inhibition of p38 mitogen-activated protein kinase attenuates left ventricular dysfunction by mediating pro-inflammatory cardiac cytokine levels in a mouse model of diabetes mellitus. Diabetologia. 2006;49:2507-13.
    • (2006) Diabetologia. , vol.49 , pp. 2507-2513
    • Westermann, D.1    Rutschow, S.2    Van Linthout, S.3    Linderer, A.4    Bucker-Gartner, C.5    Sobirey, M.6
  • 35
    • 84925678067 scopus 로고    scopus 로고
    • Relaxin: a novel agent for the treatment of acute heart failure
    • Wilson SS, Ayaz SI, Levy PD. Relaxin: a novel agent for the treatment of acute heart failure. Pharmacotherapy. 2015;35:315-27.
    • (2015) Pharmacotherapy. , vol.35 , pp. 315-327
    • Wilson, S.S.1    Ayaz, S.I.2    Levy, P.D.3
  • 36
    • 0037370388 scopus 로고    scopus 로고
    • Chronic beta2-adrenergic receptor stimulation increases proliferation of human cardiac fibroblasts via an autocrine mechanism
    • Turner NA, Porter KE, Smith WH, White HL, Ball SG, Balmforth AJ. Chronic beta2-adrenergic receptor stimulation increases proliferation of human cardiac fibroblasts via an autocrine mechanism. Cardiovasc Res. 2003;57:784-92.
    • (2003) Cardiovasc Res. , vol.57 , pp. 784-792
    • Turner, N.A.1    Porter, K.E.2    Smith, W.H.3    White, H.L.4    Ball, S.G.5    Balmforth, A.J.6
  • 37
    • 1342302820 scopus 로고    scopus 로고
    • Simvastatin reduces human atrial myofibroblast proliferation independently of cholesterol lowering via inhibition of RhoA
    • Porter KE, Turner NA, O'Regan DJ, Balmforth AJ, Ball SG. Simvastatin reduces human atrial myofibroblast proliferation independently of cholesterol lowering via inhibition of RhoA. Cardiovasc Res. 2004;61:745-55.
    • (2004) Cardiovasc Res. , vol.61 , pp. 745-755
    • Porter, K.E.1    Turner, N.A.2    O'Regan, D.J.3    Balmforth, A.J.4    Ball, S.G.5
  • 38
    • 84919474064 scopus 로고    scopus 로고
    • Timing underpins the benefits associated with injectable collagen biomaterial therapy for the treatment of myocardial infarction
    • Blackburn NJ, Sofrenovic T, Kuraitis D, Ahmadi A, McNeill B, Deng C, et al. Timing underpins the benefits associated with injectable collagen biomaterial therapy for the treatment of myocardial infarction. Biomaterials. 2015;39:182-92.
    • (2015) Biomaterials. , vol.39 , pp. 182-192
    • Blackburn, N.J.1    Sofrenovic, T.2    Kuraitis, D.3    Ahmadi, A.4    McNeill, B.5    Deng, C.6
  • 39
    • 84923067078 scopus 로고    scopus 로고
    • Delivery of alginate-chitosan hydrogel promotes endogenous repair and preserves cardiac function in rats with myocardial infarction
    • Deng B, Shen L, Wu Y, Shen Y, Ding X, Lu S, et al. Delivery of alginate-chitosan hydrogel promotes endogenous repair and preserves cardiac function in rats with myocardial infarction. J Biomed Mater Res A. 2015;103:907-18.
    • (2015) J Biomed Mater Res A. , vol.103 , pp. 907-918
    • Deng, B.1    Shen, L.2    Wu, Y.3    Shen, Y.4    Ding, X.5    Lu, S.6
  • 40
    • 78649991308 scopus 로고    scopus 로고
    • Anti-inflammatory polymeric coatings for implantable biomaterials and devices
    • Bridges AW, García AJ. Anti-inflammatory polymeric coatings for implantable biomaterials and devices. J Diabetes Sci Technol. 2008;2:984-94.
    • (2008) J Diabetes Sci Technol. , vol.2 , pp. 984-994
    • Bridges, A.W.1    García, A.J.2
  • 41
    • 77953683474 scopus 로고    scopus 로고
    • Cellular cardiomyoplasty and cardiac tissue engineering for myocardial therapy
    • Wang F, Guan J. Cellular cardiomyoplasty and cardiac tissue engineering for myocardial therapy. Adv Drug Deliv Rev. 2010;62:784-97.
    • (2010) Adv Drug Deliv Rev. , vol.62 , pp. 784-797
    • Wang, F.1    Guan, J.2
  • 42
    • 84951839805 scopus 로고    scopus 로고
    • Decellularized myocardial matrix hydrogels: In basic research and preclinical studies
    • Wang RM, Christman KL. Decellularized myocardial matrix hydrogels: In basic research and preclinical studies. Adv Drug Deliv Rev. 2016;96:77-82.
    • (2016) Adv Drug Deliv Rev. , vol.96 , pp. 77-82
    • Wang, R.M.1    Christman, K.L.2
  • 43
    • 84951129164 scopus 로고    scopus 로고
    • Inflammatory and fibrotic responses of cardiac fibroblasts to myocardial damage associated molecular patterns (DAMPs)
    • Turner NA. Inflammatory and fibrotic responses of cardiac fibroblasts to myocardial damage associated molecular patterns (DAMPs). J Mol Cell Cardiol. 2015;94:189.
    • (2015) J Mol Cell Cardiol. , vol.94 , pp. 189
    • Turner, N.A.1
  • 44
    • 18044387835 scopus 로고    scopus 로고
    • Hepatocyte growth factor prevents tissue fibrosis, remodeling, and dysfunction in cardiomyopathic hamster hearts
    • Nakamura T, Matsumoto K, Mizuno S, Sawa Y, Matsuda H, Nakamura T. Hepatocyte growth factor prevents tissue fibrosis, remodeling, and dysfunction in cardiomyopathic hamster hearts. Am J Physiol Heart Circ Physiol. 2005;288:H2131-9.
    • (2005) Am J Physiol Heart Circ Physiol. , vol.288 , pp. H2131-H2139
    • Nakamura, T.1    Matsumoto, K.2    Mizuno, S.3    Sawa, Y.4    Matsuda, H.5    Nakamura, T.6
  • 45
    • 84878291103 scopus 로고    scopus 로고
    • Interactions of U937 macrophage-like cells with decellularized pericardial matrix materials: influence of crosslinking treatment
    • McDade JK, Brennan-Pierce EP, Ariganello MB, Labow RS, Michael LJ. Interactions of U937 macrophage-like cells with decellularized pericardial matrix materials: influence of crosslinking treatment. Acta Biomater. 2013; 9:7191-9.
    • (2013) Acta Biomater. , vol.9 , pp. 7191-7199
    • McDade, J.K.1    Brennan-Pierce, E.P.2    Ariganello, M.B.3    Labow, R.S.4    Michael, L.J.5
  • 46
    • 84922022241 scopus 로고    scopus 로고
    • Delivery of an engineered HGF fragment in an extracellular matrix-derived hydrogel prevents negative LV remodeling post-myocardial infarction
    • Sonnenberg SB, Rane AA, Liu CJ, Rao N, Agmon G, Suarez S, et al. Delivery of an engineered HGF fragment in an extracellular matrix-derived hydrogel prevents negative LV remodeling post-myocardial infarction. Biomaterials. 2015;45:56-63.
    • (2015) Biomaterials. , vol.45 , pp. 56-63
    • Sonnenberg, S.B.1    Rane, A.A.2    Liu, C.J.3    Rao, N.4    Agmon, G.5    Suarez, S.6
  • 47
    • 84958034324 scopus 로고    scopus 로고
    • Timing effect of intramyocardial hydrogel injection for positively impacting left ventricular remodeling after myocardial infarction
    • Yoshizumi T, Zhu Y, Jiang H, D'Amore A, Sakaguchi H, Tchao J, et al. Timing effect of intramyocardial hydrogel injection for positively impacting left ventricular remodeling after myocardial infarction. Biomaterials. 2016;83: 182-93.
    • (2016) Biomaterials. , vol.83 , pp. 182-193
    • Yoshizumi, T.1    Zhu, Y.2    Jiang, H.3    D'Amore, A.4    Sakaguchi, H.5    Tchao, J.6
  • 48
    • 0034720847 scopus 로고    scopus 로고
    • Left ventricular remodeling after myocardial infarction: pathophysiology and therapy
    • Sutton MG, Sharpe N. Left ventricular remodeling after myocardial infarction: pathophysiology and therapy. Circulation. 2000;101:2981-8.
    • (2000) Circulation. , vol.101 , pp. 2981-2988
    • Sutton, M.G.1    Sharpe, N.2
  • 49
    • 80052974684 scopus 로고    scopus 로고
    • Interplay of hypertension, inflammation, and angiotensin II
    • Lahera V, Cachofeiro V, de Las Heras N. Interplay of hypertension, inflammation, and angiotensin II. Am J Hypertens. 2011;24:1059.
    • (2011) Am J Hypertens. , vol.24 , pp. 1059
    • Lahera, V.1    Cachofeiro, V.2    de Las Heras, N.3
  • 50
    • 77955270565 scopus 로고    scopus 로고
    • Monocytic fibroblast precursors mediate fibrosis in angiotensin-II-induced cardiac hypertrophy
    • Haudek SB, Cheng J, Du J, Wang Y, Hermosillo-Rodriguez J, Trial J, et al. Monocytic fibroblast precursors mediate fibrosis in angiotensin-II-induced cardiac hypertrophy. J Mol Cell Cardiol. 2010;49:499-507.
    • (2010) J Mol Cell Cardiol. , vol.49 , pp. 499-507
    • Haudek, S.B.1    Cheng, J.2    Du, J.3    Wang, Y.4    Hermosillo-Rodriguez, J.5    Trial, J.6
  • 51
    • 79958820082 scopus 로고    scopus 로고
    • Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47(phox) NADPH oxidase subunit
    • Bodiga S, Zhong JC, Wang W, Basu R, Lo J, Liu GC, et al. Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47(phox) NADPH oxidase subunit. Cardiovasc Res. 2011;91:151-61.
    • (2011) Cardiovasc Res. , vol.91 , pp. 151-161
    • Bodiga, S.1    Zhong, J.C.2    Wang, W.3    Basu, R.4    Lo, J.5    Liu, G.C.6
  • 52
    • 23844523196 scopus 로고    scopus 로고
    • Structure and mechanics of healing myocardial infarcts
    • Holmes JW, Borg TK, Covell JW. Structure and mechanics of healing myocardial infarcts. Annu Rev Biomed Eng. 2005;7:223-53.
    • (2005) Annu Rev Biomed Eng. , vol.7 , pp. 223-253
    • Holmes, J.W.1    Borg, T.K.2    Covell, J.W.3
  • 53
    • 84922031820 scopus 로고    scopus 로고
    • An autologous platelet-rich plasma hydrogel compound restores left ventricular structure, function and ameliorates adverse remodeling in a minimally invasive large animal myocardial restoration model: a translational approach: Vu and Pal "Myocardial Repair: PRP, Hydrogel and Supplements"
    • Vu TD, Pal SN, Ti LK, Martinez EC, Rufaihah AJ, Ling LH, et al. An autologous platelet-rich plasma hydrogel compound restores left ventricular structure, function and ameliorates adverse remodeling in a minimally invasive large animal myocardial restoration model: a translational approach: Vu and Pal "Myocardial Repair: PRP, Hydrogel and Supplements". Biomaterials. 2015; 45:27-35.
    • (2015) Biomaterials. , vol.45 , pp. 27-35
    • Vu, T.D.1    Pal, S.N.2    Ti, L.K.3    Martinez, E.C.4    Rufaihah, A.J.5    Ling, L.H.6
  • 54
    • 52449131191 scopus 로고    scopus 로고
    • Post-infarct treatment with an erythropoietin-gelatin hydrogel drug delivery system for cardiac repair
    • Kobayashi H, Minatoguchi S, Yasuda S, Bao N, Kawamura I, Iwasa M, et al. Post-infarct treatment with an erythropoietin-gelatin hydrogel drug delivery system for cardiac repair. Cardiovasc Res. 2008;79:611-20.
    • (2008) Cardiovasc Res. , vol.79 , pp. 611-620
    • Kobayashi, H.1    Minatoguchi, S.2    Yasuda, S.3    Bao, N.4    Kawamura, I.5    Iwasa, M.6
  • 56
    • 20944452151 scopus 로고    scopus 로고
    • Hepatocyte growth factor ameliorates the progression of experimental autoimmune myocarditis: a potential role for induction of T helper 2 cytokines
    • Futamatsu H, Suzuki J, Mizuno S, Koga N, Adachi S, Kosuge H, et al. Hepatocyte growth factor ameliorates the progression of experimental autoimmune myocarditis: a potential role for induction of T helper 2 cytokines. Circ Res. 2005;96:823-30.
    • (2005) Circ Res. , vol.96 , pp. 823-830
    • Futamatsu, H.1    Suzuki, J.2    Mizuno, S.3    Koga, N.4    Adachi, S.5    Kosuge, H.6
  • 57
    • 78650770246 scopus 로고    scopus 로고
    • Hepatocyte growth factor twenty years on: Much more than a growth factor
    • Nakamura T, Sakai K, Nakamura T, Matsumoto K. Hepatocyte growth factor twenty years on: Much more than a growth factor. J Gastroenterol Hepatol. 2011;26 Suppl 1:188-202.
    • (2011) J Gastroenterol Hepatol. , vol.26 , pp. 188-202
    • Nakamura, T.1    Sakai, K.2    Nakamura, T.3    Matsumoto, K.4
  • 58
    • 0034995177 scopus 로고    scopus 로고
    • A potential cardioprotective role of hepatocyte growth factor in myocardial infarction in rats
    • Ueda H, Nakamura T, Matsumoto K, Sawa Y, Matsuda H, Nakamura T. A potential cardioprotective role of hepatocyte growth factor in myocardial infarction in rats. Cardiovasc Res. 2001;51:41-50.
    • (2001) Cardiovasc Res. , vol.51 , pp. 41-50
    • Ueda, H.1    Nakamura, T.2    Matsumoto, K.3    Sawa, Y.4    Matsuda, H.5    Nakamura, T.6
  • 59
    • 0034526510 scopus 로고    scopus 로고
    • Myocardial protection from ischemia/reperfusion injury by endogenous and exogenous HGF
    • Nakamura T, Mizuno S, Matsumoto K, Sawa Y, Matsuda H, Nakamura T. Myocardial protection from ischemia/reperfusion injury by endogenous and exogenous HGF. J Clin Invest. 2000;106:1511-9.
    • (2000) J Clin Invest. , vol.106 , pp. 1511-1519
    • Nakamura, T.1    Mizuno, S.2    Matsumoto, K.3    Sawa, Y.4    Matsuda, H.5    Nakamura, T.6
  • 60
    • 0037841974 scopus 로고    scopus 로고
    • Postinfarction treatment with an adenoviral vector expressing hepatocyte growth factor relieves chronic left ventricular remodeling and dysfunction in mice
    • Li Y, Takemura G, Kosai K, Yuge K, Nagano S, Esaki M, et al. Postinfarction treatment with an adenoviral vector expressing hepatocyte growth factor relieves chronic left ventricular remodeling and dysfunction in mice. Circulation. 2003;107:2499-506.
    • (2003) Circulation. , vol.107 , pp. 2499-2506
    • Li, Y.1    Takemura, G.2    Kosai, K.3    Yuge, K.4    Nagano, S.5    Esaki, M.6
  • 61
    • 84894647247 scopus 로고    scopus 로고
    • Effects of hepatocyte growth factor in myocarditis rats induced by immunization with porcine cardiac myosin
    • Nakano J, Marui A, Muranaka H, Masumoto H, Noma H, Tabata Y, et al. Effects of hepatocyte growth factor in myocarditis rats induced by immunization with porcine cardiac myosin. Interact Cardiovasc Thorac Surg. 2014;18:300-7.
    • (2014) Interact Cardiovasc Thorac Surg. , vol.18 , pp. 300-307
    • Nakano, J.1    Marui, A.2    Muranaka, H.3    Masumoto, H.4    Noma, H.5    Tabata, Y.6
  • 62
    • 84859377039 scopus 로고    scopus 로고
    • Protein engineered variants of hepatocyte growth factor/scatter factor promote proliferation of primary human hepatocytes and in rodent liver
    • Ross J, Gherardi E, Mallorqui-Fernandez N, Bocci M, Sobkowicz A, Rees M, et al. Protein engineered variants of hepatocyte growth factor/scatter factor promote proliferation of primary human hepatocytes and in rodent liver. Gastroenterology. 2012;142:897-906.
    • (2012) Gastroenterology. , vol.142 , pp. 897-906
    • Ross, J.1    Gherardi, E.2    Mallorqui-Fernandez, N.3    Bocci, M.4    Sobkowicz, A.5    Rees, M.6
  • 63
    • 80052010599 scopus 로고    scopus 로고
    • Engineering hepatocyte growth factor fragments with high stability and activity as Met receptor agonists and antagonists
    • Jones II DS, Tsai PC, Cochran JR. Engineering hepatocyte growth factor fragments with high stability and activity as Met receptor agonists and antagonists. Proc Natl Acad Sci U S A. 2011;108:13035-40.
    • (2011) Proc Natl Acad Sci U S A. , vol.108 , pp. 13035-13040
    • Jones, D.S.1    Tsai, P.C.2    Cochran, J.R.3
  • 64
    • 84915745204 scopus 로고    scopus 로고
    • An engineered dimeric fragment of hepatocyte growth factor is a potent c-MET agonist
    • Liu CJ, Jones 2nd DS, Tsai PC, Venkataramana A, Cochran JR. An engineered dimeric fragment of hepatocyte growth factor is a potent c-MET agonist. FEBS Lett. 2014;588:4831-7.
    • (2014) FEBS Lett. , vol.588 , pp. 4831-4837
    • Liu, C.J.1    Jones, D.S.2    Tsai, P.C.3    Venkataramana, A.4    Cochran, J.R.5
  • 65
    • 81855183235 scopus 로고    scopus 로고
    • Bioengineering the infarcted heart by applying bio-inspired materials
    • Ruvinov E, Harel-Adar T, Cohen S. Bioengineering the infarcted heart by applying bio-inspired materials. J Cardiovasc Transl Res. 2011;4:559-74.
    • (2011) J Cardiovasc Transl Res. , vol.4 , pp. 559-574
    • Ruvinov, E.1    Harel-Adar, T.2    Cohen, S.3
  • 66
    • 78449253232 scopus 로고    scopus 로고
    • The promotion of myocardial repair by the sequential delivery of IGF-1 and HGF from an injectable alginate biomaterial in a model of acute myocardial infarction
    • Ruvinov E, Leor J, Cohen S. The promotion of myocardial repair by the sequential delivery of IGF-1 and HGF from an injectable alginate biomaterial in a model of acute myocardial infarction. Biomaterials. 2011;32:565-78.
    • (2011) Biomaterials. , vol.32 , pp. 565-578
    • Ruvinov, E.1    Leor, J.2    Cohen, S.3
  • 67
    • 84870577591 scopus 로고    scopus 로고
    • Dual delivery of hepatocyte and vascular endothelial growth factors via a protease-degradable hydrogel improves cardiac function in rats
    • Salimath AS, Phelps EA, Boopathy AV, Che PL, Brown M, Garcia AJ, et al. Dual delivery of hepatocyte and vascular endothelial growth factors via a protease-degradable hydrogel improves cardiac function in rats. PLoS One. 2012;7:e50980.
    • (2012) PLoS One. , vol.7
    • Salimath, A.S.1    Phelps, E.A.2    Boopathy, A.V.3    Che, P.L.4    Brown, M.5    Garcia, A.J.6
  • 68
    • 77449103235 scopus 로고    scopus 로고
    • Coadministration of adenoviral vascular endothelial growth factor and angiopoietin-1 enhances vascularization and reduces ventricular remodeling in the infarcted myocardium of type 1 diabetic rats
    • Samuel SM, Akita Y, Paul D, Thirunavukkarasu M, Zhan L, Sudhakaran PR, et al. Coadministration of adenoviral vascular endothelial growth factor and angiopoietin-1 enhances vascularization and reduces ventricular remodeling in the infarcted myocardium of type 1 diabetic rats. Diabetes. 2010;59:51-60.
    • (2010) Diabetes. , vol.59 , pp. 51-60
    • Samuel, S.M.1    Akita, Y.2    Paul, D.3    Thirunavukkarasu, M.4    Zhan, L.5    Sudhakaran, P.R.6
  • 69
    • 77952294182 scopus 로고    scopus 로고
    • Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction
    • Zentilin L, Puligadda U, Lionetti V, Zacchigna S, Collesi C, Pattarini L, et al. Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction. FASEB J. 2010;24:1467-78.
    • (2010) FASEB J. , vol.24 , pp. 1467-1478
    • Zentilin, L.1    Puligadda, U.2    Lionetti, V.3    Zacchigna, S.4    Collesi, C.5    Pattarini, L.6
  • 70
    • 67651176177 scopus 로고    scopus 로고
    • Basic fibroblast growth factor induces down-regulation of alpha-smooth muscle actin and reduction of myofibroblast areas in open skin wounds
    • Ishiguro S, Akasaka Y, Kiguchi H, Suzuki T, Imaizumi R, Ishikawa Y, et al. Basic fibroblast growth factor induces down-regulation of alpha-smooth muscle actin and reduction of myofibroblast areas in open skin wounds. Wound Repair Regen. 2009;17:617-25.
    • (2009) Wound Repair Regen. , vol.17 , pp. 617-625
    • Ishiguro, S.1    Akasaka, Y.2    Kiguchi, H.3    Suzuki, T.4    Imaizumi, R.5    Ishikawa, Y.6
  • 71
    • 79951813692 scopus 로고    scopus 로고
    • TGF-beta regulates isoform switching of FGF receptors and epithelialmesenchymal transition
    • Shirakihara T, Horiguchi K, Miyazawa K, Ehata S, Shibata T, Morita I, et al. TGF-beta regulates isoform switching of FGF receptors and epithelialmesenchymal transition. EMBO J. 2011;30:783-95.
    • (2011) EMBO J. , vol.30 , pp. 783-795
    • Shirakihara, T.1    Horiguchi, K.2    Miyazawa, K.3    Ehata, S.4    Shibata, T.5    Morita, I.6
  • 72
    • 44949107350 scopus 로고    scopus 로고
    • Fibroblast growth factor represses Smad-mediated myofibroblast activation in aortic valvular interstitial cells
    • Cushing MC, Mariner PD, Liao JT, Sims EA, Anseth KS. Fibroblast growth factor represses Smad-mediated myofibroblast activation in aortic valvular interstitial cells. Faseb J. 2008;22:1769-77.
    • (2008) Faseb J. , vol.22 , pp. 1769-1777
    • Cushing, M.C.1    Mariner, P.D.2    Liao, J.T.3    Sims, E.A.4    Anseth, K.S.5
  • 73
    • 84929407211 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 regulates human cardiac myofibroblast-mediated extracellular matrix remodeling
    • Svystonyuk DA, Ngu JM, Mewhort HE, Lipon BD, Teng G, Guzzardi DG, et al. Fibroblast growth factor-2 regulates human cardiac myofibroblast-mediated extracellular matrix remodeling. J Transl Med. 2015;13:147.
    • (2015) J Transl Med. , vol.13 , pp. 147
    • Svystonyuk, D.A.1    Ngu, J.M.2    Mewhort, H.E.3    Lipon, B.D.4    Teng, G.5    Guzzardi, D.G.6
  • 74
    • 84901350078 scopus 로고    scopus 로고
    • High molecular weight fibroblast growth factor-2 in the human heart is a potential target for prevention of cardiac remodeling
    • Santiago JJ, McNaughton LJ, Koleini N, Ma X, Bestvater B, Nickel BE, et al. High molecular weight fibroblast growth factor-2 in the human heart is a potential target for prevention of cardiac remodeling. PLoS One. 2014; 9:e97281.
    • (2014) PLoS One. , vol.9
    • Santiago, J.J.1    McNaughton, L.J.2    Koleini, N.3    Ma, X.4    Bestvater, B.5    Nickel, B.E.6
  • 75
    • 73349122017 scopus 로고    scopus 로고
    • Cardiac fibroblast: the renaissance cell
    • Souders CA, Bowers SL, Baudino TA. Cardiac fibroblast: the renaissance cell. Circ Res. 2009;105:1164-76.
    • (2009) Circ Res. , vol.105 , pp. 1164-1176
    • Souders, C.A.1    Bowers, S.L.2    Baudino, T.A.3
  • 76
    • 80052293274 scopus 로고    scopus 로고
    • Arteriogenic therapy by intramyocardial sustained delivery of a novel growth factor combination prevents chronic heart failure
    • Banquet S, Gomez E, Nicol L, Edwards-Levy F, Henry JP, Cao R, et al. Arteriogenic therapy by intramyocardial sustained delivery of a novel growth factor combination prevents chronic heart failure. Circulation. 2011; 124:1059-69.
    • (2011) Circulation. , vol.124 , pp. 1059-1069
    • Banquet, S.1    Gomez, E.2    Nicol, L.3    Edwards-Levy, F.4    Henry, J.P.5    Cao, R.6
  • 77
    • 84863062546 scopus 로고    scopus 로고
    • Notch signaling may negatively regulate neonatal rat cardiac fibroblast-myofibroblast transformation
    • Fan YH, Dong H, Pan Q, Cao YJ, Li H, Wang HC. Notch signaling may negatively regulate neonatal rat cardiac fibroblast-myofibroblast transformation. Physiol Res. 2011;60:739-48.
    • (2011) Physiol Res. , vol.60 , pp. 739-748
    • Fan, Y.H.1    Dong, H.2    Pan, Q.3    Cao, Y.J.4    Li, H.5    Wang, H.C.6
  • 78
    • 84940664298 scopus 로고    scopus 로고
    • Intramyocardial delivery of Notch ligand-containing hydrogels improves cardiac function and angiogenesis following infarction
    • Boopathy AV, Martinez MD, Smith AW, Brown ME, Garcia AJ, Davis ME. Intramyocardial delivery of Notch ligand-containing hydrogels improves cardiac function and angiogenesis following infarction. Tissue Eng Part A. 2015;21:2315-22.
    • (2015) Tissue Eng Part A. , vol.21 , pp. 2315-2322
    • Boopathy, A.V.1    Martinez, M.D.2    Smith, A.W.3    Brown, M.E.4    Garcia, A.J.5    Davis, M.E.6
  • 79
    • 67649971239 scopus 로고    scopus 로고
    • Long-term outcome of stem cell therapy for acute myocardial infarction: right results, wrong reasons
    • Forrester JS, Makkar RR, Marban E. Long-term outcome of stem cell therapy for acute myocardial infarction: right results, wrong reasons. J Am Coll Cardiol. 2009;53:2270-2.
    • (2009) J Am Coll Cardiol. , vol.53 , pp. 2270-2272
    • Forrester, J.S.1    Makkar, R.R.2    Marban, E.3
  • 80
    • 84891151361 scopus 로고    scopus 로고
    • Improving survival and efficacy of pluripotent stem cellderived cardiac grafts
    • Don CW, Murry CE. Improving survival and efficacy of pluripotent stem cellderived cardiac grafts. J Cell Mol Med. 2013;17:1355-62.
    • (2013) J Cell Mol Med. , vol.17 , pp. 1355-1362
    • Don, C.W.1    Murry, C.E.2
  • 82
    • 84878850858 scopus 로고    scopus 로고
    • Cardiac stem cell therapy and the promise of heart regeneration
    • Garbern JC, Lee RT. Cardiac stem cell therapy and the promise of heart regeneration. Cell Stem Cell. 2013;12:689-98.
    • (2013) Cell Stem Cell. , vol.12 , pp. 689-698
    • Garbern, J.C.1    Lee, R.T.2
  • 83
    • 84907305378 scopus 로고    scopus 로고
    • Translating stem cell research to cardiac disease therapies: pitfalls and prospects for improvement
    • Rosen MR, Myerburg RJ, Francis DP, Cole GD, Marban E. Translating stem cell research to cardiac disease therapies: pitfalls and prospects for improvement. J Am Coll Cardiol. 2014;64:922-37.
    • (2014) J Am Coll Cardiol. , vol.64 , pp. 922-937
    • Rosen, M.R.1    Myerburg, R.J.2    Francis, D.P.3    Cole, G.D.4    Marban, E.5
  • 84
    • 84923535492 scopus 로고    scopus 로고
    • An emerging consensus on cardiac regeneration
    • van Berlo JH, Molkentin JD. An emerging consensus on cardiac regeneration. Nat Med. 2014;20:1386-93.
    • (2014) Nat Med. , vol.20 , pp. 1386-1393
    • van Berlo, J.H.1    Molkentin, J.D.2
  • 85
    • 24044535092 scopus 로고    scopus 로고
    • Transplantation of mesenchymal stem cells improves cardiac function in a rat model of dilated cardiomyopathy
    • Nagaya N, Kangawa K, Itoh T, Iwase T, Murakami S, Miyahara Y, et al. Transplantation of mesenchymal stem cells improves cardiac function in a rat model of dilated cardiomyopathy. Circulation. 2005;112:1128-35.
    • (2005) Circulation. , vol.112 , pp. 1128-1135
    • Nagaya, N.1    Kangawa, K.2    Itoh, T.3    Iwase, T.4    Murakami, S.5    Miyahara, Y.6
  • 86
    • 33646252939 scopus 로고    scopus 로고
    • Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cellmediated cardiac protection and functional improvement
    • Gnecchi M, He H, Noiseux N, Liang OD, Zhang L, Morello F, et al. Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cellmediated cardiac protection and functional improvement. FASEB J. 2006; 20:661-9.
    • (2006) FASEB J. , vol.20 , pp. 661-669
    • Gnecchi, M.1    He, H.2    Noiseux, N.3    Liang, O.D.4    Zhang, L.5    Morello, F.6
  • 87
    • 34748892483 scopus 로고    scopus 로고
    • Bone marrow derived mesenchymal cell mobilization by granulocytecolony stimulating factor after acute myocardial infarction: results from the Stem Cells in Myocardial Infarction (STEMMI) trial
    • Ripa RS, Haack-Sorensen M, Wang Y, Jorgensen E, Mortensen S, Bindslev L, et al. Bone marrow derived mesenchymal cell mobilization by granulocytecolony stimulating factor after acute myocardial infarction: results from the Stem Cells in Myocardial Infarction (STEMMI) trial. Circulation. 2007;116:I24-30.
    • (2007) Circulation. , vol.116 , pp. I24-30
    • Ripa, R.S.1    Haack-Sorensen, M.2    Wang, Y.3    Jorgensen, E.4    Mortensen, S.5    Bindslev, L.6
  • 88
    • 70549103270 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction
    • Hare JM, Traverse JH, Henry TD, Dib N, Strumpf RK, Schulman SP, et al. A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction. J Am Coll Cardiol. 2009;54:2277-86.
    • (2009) J Am Coll Cardiol. , vol.54 , pp. 2277-2286
    • Hare, J.M.1    Traverse, J.H.2    Henry, T.D.3    Dib, N.4    Strumpf, R.K.5    Schulman, S.P.6
  • 89
    • 77956364230 scopus 로고    scopus 로고
    • Results of a phase 1, randomized, double-blind, placebo-controlled trial of bone marrow mononuclear stem cell administration in patients following ST-elevation myocardial infarction
    • Traverse JH, McKenna DH, Harvey K, Jorgenso BC, Olson RE, Bostrom N, et al. Results of a phase 1, randomized, double-blind, placebo-controlled trial of bone marrow mononuclear stem cell administration in patients following ST-elevation myocardial infarction. Am Heart J. 2010;160:428-34.
    • (2010) Am Heart J. , vol.160 , pp. 428-434
    • Traverse, J.H.1    McKenna, D.H.2    Harvey, K.3    Jorgenso, B.C.4    Olson, R.E.5    Bostrom, N.6
  • 90
    • 84883445522 scopus 로고    scopus 로고
    • Bone-derived stem cells repair the heart after myocardial infarction through transdifferentiation and paracrine signaling mechanisms
    • Duran JM, Makarewich CA, Sharp TE, Starosta T, Zhu F, Hoffman NE, et al. Bone-derived stem cells repair the heart after myocardial infarction through transdifferentiation and paracrine signaling mechanisms. Circ Res. 2013; 113:539-52.
    • (2013) Circ Res. , vol.113 , pp. 539-552
    • Duran, J.M.1    Makarewich, C.A.2    Sharp, T.E.3    Starosta, T.4    Zhu, F.5    Hoffman, N.E.6
  • 91
    • 0036142213 scopus 로고    scopus 로고
    • Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart
    • Toma C, Pittenger MF, Cahill KS, Byrne BJ, Kessler PD. Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation. 2002;105:93-8.
    • (2002) Circulation. , vol.105 , pp. 93-98
    • Toma, C.1    Pittenger, M.F.2    Cahill, K.S.3    Byrne, B.J.4    Kessler, P.D.5
  • 92
    • 33845748551 scopus 로고    scopus 로고
    • 5-Azacytidine induces changes in electrophysiological properties of human mesenchymal stem cells
    • Balana B, Nicoletti C, Zahanich I, Graf EM, Christ T, Boxberger S, et al. 5-Azacytidine induces changes in electrophysiological properties of human mesenchymal stem cells. Cell Res. 2006;16:949-60.
    • (2006) Cell Res. , vol.16 , pp. 949-960
    • Balana, B.1    Nicoletti, C.2    Zahanich, I.3    Graf, E.M.4    Christ, T.5    Boxberger, S.6
  • 93
    • 84855446143 scopus 로고    scopus 로고
    • 5-azacytidine induces cardiac differentiation of human umbilical cord-derived mesenchymal stem cells by activating extracellular regulated kinase
    • Qian Q, Qian H, Zhang X, Zhu W, Yan YM, Ye SQ, et al. 5-azacytidine induces cardiac differentiation of human umbilical cord-derived mesenchymal stem cells by activating extracellular regulated kinase. Stem Cells Dev. 2012;21:67-75.
    • (2012) Stem Cells Dev. , vol.21 , pp. 67-75
    • Qian, Q.1    Qian, H.2    Zhang, X.3    Zhu, W.4    Yan, Y.M.5    Ye, S.Q.6
  • 94
    • 38849117016 scopus 로고    scopus 로고
    • Direct intramyocardial injection of mesenchymal stem cell sheet fragments improves cardiac functions after infarction
    • Wang CC, Chen CH, Lin WW, Hwang SM, Hsieh PCH, Lai PH, et al. Direct intramyocardial injection of mesenchymal stem cell sheet fragments improves cardiac functions after infarction. Cardiovasc Res. 2008;77:515-24.
    • (2008) Cardiovasc Res. , vol.77 , pp. 515-524
    • Wang, C.C.1    Chen, C.H.2    Lin, W.W.3    Hwang, S.M.4    Hsieh, P.C.H.5    Lai, P.H.6
  • 95
    • 79151470214 scopus 로고    scopus 로고
    • Adult stem cells for cardiac tissue engineering
    • Martinez EC, Kofidis T. Adult stem cells for cardiac tissue engineering. J Mol Cell Cardiol. 2011;50:312-9.
    • (2011) J Mol Cell Cardiol. , vol.50 , pp. 312-319
    • Martinez, E.C.1    Kofidis, T.2
  • 96
    • 80052344467 scopus 로고    scopus 로고
    • Imaging long-term fate of intramyocardially implanted mesenchymal stem cells in a porcine myocardial infarction model
    • Perin EC, Tian M, Marini FC, Silva GV, Zheng Y, Baimbridge F, et al. Imaging long-term fate of intramyocardially implanted mesenchymal stem cells in a porcine myocardial infarction model. Plos One. 2011;6:e22949.
    • (2011) Plos One. , vol.6
    • Perin, E.C.1    Tian, M.2    Marini, F.C.3    Silva, G.V.4    Zheng, Y.5    Baimbridge, F.6
  • 97
    • 3142663241 scopus 로고    scopus 로고
    • Mesenchymal stem cells and their potential as cardiac therapeutics
    • Pittenger MF, Martin BJ. Mesenchymal stem cells and their potential as cardiac therapeutics. Circ Res. 2004;95:9-20.
    • (2004) Circ Res. , vol.95 , pp. 9-20
    • Pittenger, M.F.1    Martin, B.J.2
  • 98
    • 72849145234 scopus 로고    scopus 로고
    • Mesenchymal stem cells promote matrix metalloproteinase secretion by cardiac fibroblasts and reduce cardiac ventricular fibrosis after myocardial infarction
    • Mias C, Lairez O, Trouche E, Roncalli J, Calise D, Seguelas MH, et al. Mesenchymal stem cells promote matrix metalloproteinase secretion by cardiac fibroblasts and reduce cardiac ventricular fibrosis after myocardial infarction. Stem Cells. 2009;27:2734-43.
    • (2009) Stem Cells. , vol.27 , pp. 2734-2743
    • Mias, C.1    Lairez, O.2    Trouche, E.3    Roncalli, J.4    Calise, D.5    Seguelas, M.H.6
  • 99
    • 84863115781 scopus 로고    scopus 로고
    • Paracrine effect of Wnt11-overexpressing mesenchymal stem cells on ischemic injury
    • Zuo S, Jones WK, Li HX, He ZS, Pasha ZS, Yang YT, et al. Paracrine effect of Wnt11-overexpressing mesenchymal stem cells on ischemic injury. Stem Cells Dev. 2012;21:598-608.
    • (2012) Stem Cells Dev. , vol.21 , pp. 598-608
    • Zuo, S.1    Jones, W.K.2    Li, H.X.3    He, Z.S.4    Pasha, Z.S.5    Yang, Y.T.6
  • 100
    • 42749084257 scopus 로고    scopus 로고
    • Transplantation of adipose derived stromal cells is associated with functional improvement in a rat model of chronic myocardial infarction
    • Mazo M, Planat-Benard V, Abizanda G, Pelacho B, Leobon B, Gavira JJ, et al. Transplantation of adipose derived stromal cells is associated with functional improvement in a rat model of chronic myocardial infarction. Eur J Heart Fail. 2008;10:454-62.
    • (2008) Eur J Heart Fail. , vol.10 , pp. 454-462
    • Mazo, M.1    Planat-Benard, V.2    Abizanda, G.3    Pelacho, B.4    Leobon, B.5    Gavira, J.J.6
  • 101
    • 84879440284 scopus 로고    scopus 로고
    • Treatment of reperfused ischemia with adipose-derived stem cells in a preclinical Swine model of myocardial infarction
    • Mazo M, Hernandez S, Gavira JJ, Abizanda G, Arana M, Lopez-Martinez T, et al. Treatment of reperfused ischemia with adipose-derived stem cells in a preclinical Swine model of myocardial infarction. Cell Transplant. 2012; 21:2723-33.
    • (2012) Cell Transplant. , vol.21 , pp. 2723-2733
    • Mazo, M.1    Hernandez, S.2    Gavira, J.J.3    Abizanda, G.4    Arana, M.5    Lopez-Martinez, T.6
  • 102
    • 84878511606 scopus 로고    scopus 로고
    • Transplantation of modified human adipose derived stromal cells expressing VEGF165 results in more efficient angiogenic response in ischemic skeletal muscle
    • Shevchenko EK, Makarevich PI, Tsokolaeva ZI, Boldyreva MA, Sysoeva VY, Tkachuk VA, et al. Transplantation of modified human adipose derived stromal cells expressing VEGF165 results in more efficient angiogenic response in ischemic skeletal muscle. J Transl Med. 2013;11:138.
    • (2013) J Transl Med. , vol.11 , pp. 138
    • Shevchenko, E.K.1    Makarevich, P.I.2    Tsokolaeva, Z.I.3    Boldyreva, M.A.4    Sysoeva, V.Y.5    Tkachuk, V.A.6
  • 105
    • 84866458852 scopus 로고    scopus 로고
    • Administration of cardiac stem cells in patients with ischemic cardiomyopathy: the SCIPIO trial: surgical aspects and interim analysis of myocardial function and viability by magnetic resonance
    • Chugh AR, Beache GM, Loughran JH, Mewton N, Elmore JB, Kajstura J, et al. Administration of cardiac stem cells in patients with ischemic cardiomyopathy: the SCIPIO trial: surgical aspects and interim analysis of myocardial function and viability by magnetic resonance. Circulation. 2012; 126:S54-64.
    • (2012) Circulation. , vol.126 , pp. S54-64
    • Chugh, A.R.1    Beache, G.M.2    Loughran, J.H.3    Mewton, N.4    Elmore, J.B.5    Kajstura, J.6
  • 106
    • 84880098987 scopus 로고    scopus 로고
    • Intracoronary delivery of autologous cardiac stem cells improves cardiac function in a porcine model of chronic ischemic cardiomyopathy
    • Bolli R, Tang XL, Sanganalmath SK, Rimoldi O, Mosna F, Abdel-Latif A, et al. Intracoronary delivery of autologous cardiac stem cells improves cardiac function in a porcine model of chronic ischemic cardiomyopathy. Circulation. 2013;128:122-31.
    • (2013) Circulation. , vol.128 , pp. 122-131
    • Bolli, R.1    Tang, X.L.2    Sanganalmath, S.K.3    Rimoldi, O.4    Mosna, F.5    Abdel-Latif, A.6
  • 107
    • 84883798654 scopus 로고    scopus 로고
    • Human blood and cardiac stem cells synergize to enhance cardiac repair when cotransplanted into ischemic myocardium
    • Latham N, Ye B, Jackson R, Lam BK, Kuraitis D, Ruel M, et al. Human blood and cardiac stem cells synergize to enhance cardiac repair when cotransplanted into ischemic myocardium. Circulation. 2013;128:S105-12.
    • (2013) Circulation. , vol.128 , pp. S105-S112
    • Latham, N.1    Ye, B.2    Jackson, R.3    Lam, B.K.4    Kuraitis, D.5    Ruel, M.6
  • 108
    • 84872281137 scopus 로고    scopus 로고
    • Enhanced effect of combining human cardiac stem cells and bone marrow mesenchymal stem cells to reduce infarct size and to restore cardiac function after myocardial infarction
    • Williams AR, Hatzistergos KE, Addicott B, McCall F, Carvalho D, Suncion V, et al. Enhanced effect of combining human cardiac stem cells and bone marrow mesenchymal stem cells to reduce infarct size and to restore cardiac function after myocardial infarction. Circulation. 2013;127:213-23.
    • (2013) Circulation. , vol.127 , pp. 213-223
    • Williams, A.R.1    Hatzistergos, K.E.2    Addicott, B.3    McCall, F.4    Carvalho, D.5    Suncion, V.6
  • 109
    • 84883740296 scopus 로고    scopus 로고
    • A HCN4+ cardiomyogenic progenitor derived from the first heart field and human pluripotent stem cells
    • Spater D, Abramczuk MK, Buac K, Zangi L, Stachel MW, Clarke J, et al. A HCN4+ cardiomyogenic progenitor derived from the first heart field and human pluripotent stem cells. Nat Cell Biol. 2013;15:1098-106.
    • (2013) Nat Cell Biol. , vol.15 , pp. 1098-1106
    • Spater, D.1    Abramczuk, M.K.2    Buac, K.3    Zangi, L.4    Stachel, M.W.5    Clarke, J.6
  • 110
    • 84867287177 scopus 로고    scopus 로고
    • Characterization and therapeutic potential of induced pluripotent stem cell-derived cardiovascular progenitor cells
    • Nsair A, Schenke-Layland K, Van Handel B, Evseenko D, Kahn M, Zhao P, et al. Characterization and therapeutic potential of induced pluripotent stem cell-derived cardiovascular progenitor cells. PLoS One. 2012;7:e45603.
    • (2012) PLoS One. , vol.7
    • Nsair, A.1    Schenke-Layland, K.2    Van Handel, B.3    Evseenko, D.4    Kahn, M.5    Zhao, P.6
  • 112
    • 33847145871 scopus 로고    scopus 로고
    • Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens
    • Smith RR, Barile L, Cho HC, Leppo MK, Hare JM, Messina E, et al. Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens. Circulation. 2007; 115:896-908.
    • (2007) Circulation. , vol.115 , pp. 896-908
    • Smith, R.R.1    Barile, L.2    Cho, H.C.3    Leppo, M.K.4    Hare, J.M.5    Messina, E.6
  • 113
    • 70349663946 scopus 로고    scopus 로고
    • Validation of the cardiosphere method to culture cardiac progenitor cells from myocardial tissue
    • Davis DR, Zhang Y, Smith RR, Cheng K, Terrovitis J, Malliaras K, et al. Validation of the cardiosphere method to culture cardiac progenitor cells from myocardial tissue. PLoS One. 2009;4:e7195.
    • (2009) PLoS One. , vol.4
    • Davis, D.R.1    Zhang, Y.2    Smith, R.R.3    Cheng, K.4    Terrovitis, J.5    Malliaras, K.6
  • 114
    • 70349661889 scopus 로고    scopus 로고
    • Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy
    • Johnston PV, Sasano T, Mills K, Evers R, Lee ST, Smith RR, et al. Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy. Circulation. 2009;120:1075-83.
    • (2009) Circulation. , vol.120 , pp. 1075-1083
    • Johnston, P.V.1    Sasano, T.2    Mills, K.3    Evers, R.4    Lee, S.T.5    Smith, R.R.6
  • 115
    • 77950890007 scopus 로고    scopus 로고
    • Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice
    • Chimenti I, Smith RR, Li TS, Gerstenblith G, Messina E, Giacomello A, et al. Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice. Circ Res. 2010; 106:971-80.
    • (2010) Circ Res. , vol.106 , pp. 971-980
    • Chimenti, I.1    Smith, R.R.2    Li, T.S.3    Gerstenblith, G.4    Messina, E.5    Giacomello, A.6
  • 117
    • 84863230134 scopus 로고    scopus 로고
    • Direct comparison of different stem cell types and subpopulations reveals superior paracrine potency and myocardial repair efficacy with cardiosphere-derived cells
    • Li TS, Cheng K, Malliaras K, Smith RR, Zhang Y, Sun B, et al. Direct comparison of different stem cell types and subpopulations reveals superior paracrine potency and myocardial repair efficacy with cardiosphere-derived cells. J Am Coll Cardiol. 2012;59:942-53.
    • (2012) J Am Coll Cardiol. , vol.59 , pp. 942-953
    • Li, T.S.1    Cheng, K.2    Malliaras, K.3    Smith, R.R.4    Zhang, Y.5    Sun, B.6
  • 118
    • 84904876156 scopus 로고    scopus 로고
    • Interleukin-6 contributes to the paracrine effects of cardiospheres cultured from human, murine and rat hearts
    • Maxeiner H, Mufti S, Krehbiehl N, Dulfer F, Helmig S, Schneider J, et al. Interleukin-6 contributes to the paracrine effects of cardiospheres cultured from human, murine and rat hearts. J Cell Physiol. 2014;229:1681-9.
    • (2014) J Cell Physiol. , vol.229 , pp. 1681-1689
    • Maxeiner, H.1    Mufti, S.2    Krehbiehl, N.3    Dulfer, F.4    Helmig, S.5    Schneider, J.6
  • 119
    • 84906278987 scopus 로고    scopus 로고
    • Importance of cell-cell contact in the therapeutic benefits of cardiosphere-derived cells
    • Xie Y, Ibrahim A, Cheng K, Wu Z, Liang W, Malliaras K, et al. Importance of cell-cell contact in the therapeutic benefits of cardiosphere-derived cells. Stem Cells. 2014;32:2397-406.
    • (2014) Stem Cells. , vol.32 , pp. 2397-2406
    • Xie, Y.1    Ibrahim, A.2    Cheng, K.3    Wu, Z.4    Liang, W.5    Malliaras, K.6
  • 120
    • 77953726551 scopus 로고    scopus 로고
    • Isolation and expansion of functionally-competent cardiac progenitor cells directly from heart biopsies
    • Davis DR, Kizana E, Terrovitis J, Barth AS, Zhang YQ, Smith RR, et al. Isolation and expansion of functionally-competent cardiac progenitor cells directly from heart biopsies. J Mol Cell Cardiol. 2010;49:312-21.
    • (2010) J Mol Cell Cardiol. , vol.49 , pp. 312-321
    • Davis, D.R.1    Kizana, E.2    Terrovitis, J.3    Barth, A.S.4    Zhang, Y.Q.5    Smith, R.R.6
  • 121
    • 70349663946 scopus 로고    scopus 로고
    • Validation of the cardiosphere method to culture cardiac progenitor cells from myocardial tissue
    • Davis DR, Zhang YQ, Smith RR, Cheng K, Terrovitis J, Malliaras K, et al. Validation of the cardiosphere method to culture cardiac progenitor cells from myocardial tissue. Plos One. 2009;4.
    • (2009) Plos One , vol.4
    • Davis, D.R.1    Zhang, Y.Q.2    Smith, R.R.3    Cheng, K.4    Terrovitis, J.5    Malliaras, K.6
  • 122
    • 78751621958 scopus 로고    scopus 로고
    • Intramyocardial injection of autologous cardiospheres or cardiospherederived cells preserves function and minimizes adverse ventricular remodeling in pigs with heart failure post-myocardial infarction
    • Lee ST, White AJ, Matsushita S, Malliaras K, Steenbergen C, Zhang Y, et al. Intramyocardial injection of autologous cardiospheres or cardiospherederived cells preserves function and minimizes adverse ventricular remodeling in pigs with heart failure post-myocardial infarction. J Am Coll Cardiol. 2011;57:455-65.
    • (2011) J Am Coll Cardiol. , vol.57 , pp. 455-465
    • Lee, S.T.1    White, A.J.2    Matsushita, S.3    Malliaras, K.4    Steenbergen, C.5    Zhang, Y.6
  • 123
    • 85031048109 scopus 로고    scopus 로고
    • Direct implantation versus platelet-rich fibrin-embedded adipose-derived mesenchymal stem cells in treating rat acute myocardial infarction
    • Sun CK, Zhen YY, Leu S, Tsai TH, Chang LT, Sheu JJ, et al. Direct implantation versus platelet-rich fibrin-embedded adipose-derived mesenchymal stem cells in treating rat acute myocardial infarction. Int J Cardiol. 2014;14:00440-9.
    • (2014) Int J Cardiol. , vol.14 , pp. 440-449
    • Sun, C.K.1    Zhen, Y.Y.2    Leu, S.3    Tsai, T.H.4    Chang, L.T.5    Sheu, J.J.6
  • 124
    • 84887026121 scopus 로고    scopus 로고
    • Epicardial delivery of collagen patches with adipose-derived stem cells in rat and minipig models of chronic myocardial infarction
    • Arana M, Gavira JJ, Pena E, Gonzalez A, Abizanda G, Cilla M, et al. Epicardial delivery of collagen patches with adipose-derived stem cells in rat and minipig models of chronic myocardial infarction. Biomaterials. 2014;35:143-51.
    • (2014) Biomaterials. , vol.35 , pp. 143-151
    • Arana, M.1    Gavira, J.J.2    Pena, E.3    Gonzalez, A.4    Abizanda, G.5    Cilla, M.6
  • 125
    • 34547685923 scopus 로고    scopus 로고
    • Mesenchymal stem cells attenuate cardiac fibroblast proliferation and collagen synthesis through paracrine actions
    • Ohnishi S, Sumiyoshi H, Kitamura S, Nagaya N. Mesenchymal stem cells attenuate cardiac fibroblast proliferation and collagen synthesis through paracrine actions. FEBS Lett. 2007;581:3961-6.
    • (2007) FEBS Lett. , vol.581 , pp. 3961-3966
    • Ohnishi, S.1    Sumiyoshi, H.2    Kitamura, S.3    Nagaya, N.4
  • 126
    • 84930448769 scopus 로고    scopus 로고
    • Enhanced infarct myocardium repair mediated by thermosensitive copolymer hydrogel-based stem cell transplantation
    • Xia Y, Zhu K, Lai H, Lang M, Xiao Y, Lian S, et al. Enhanced infarct myocardium repair mediated by thermosensitive copolymer hydrogel-based stem cell transplantation. Exp Biol Med (Maywood). 2015;240:593-600.
    • (2015) Exp Biol Med (Maywood). , vol.240 , pp. 593-600
    • Xia, Y.1    Zhu, K.2    Lai, H.3    Lang, M.4    Xiao, Y.5    Lian, S.6
  • 127
    • 84896496594 scopus 로고    scopus 로고
    • Evaluation of polyelectrolyte complex-based scaffolds for mesenchymal stem cell therapy in cardiac ischemia treatment
    • Ceccaldi C, Bushkalova R, Alfarano C, Lairez O, Calise D, Bourin P, et al. Evaluation of polyelectrolyte complex-based scaffolds for mesenchymal stem cell therapy in cardiac ischemia treatment. Acta Biomater. 2014; 10:901-11.
    • (2014) Acta Biomater. , vol.10 , pp. 901-911
    • Ceccaldi, C.1    Bushkalova, R.2    Alfarano, C.3    Lairez, O.4    Calise, D.5    Bourin, P.6
  • 128
    • 84870660564 scopus 로고    scopus 로고
    • Localization of mesenchymal stem cells grafted with a hyaluronan-based scaffold in the infarcted heart
    • Fiumana E, Pasquinelli G, Foroni L, Carboni M, Bonafe F, Orrico C, et al. Localization of mesenchymal stem cells grafted with a hyaluronan-based scaffold in the infarcted heart. J Surg Res. 2013;179:e21-9.
    • (2013) J Surg Res. , vol.179 , pp. e21-e29
    • Fiumana, E.1    Pasquinelli, G.2    Foroni, L.3    Carboni, M.4    Bonafe, F.5    Orrico, C.6
  • 129
    • 59549095389 scopus 로고    scopus 로고
    • Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating
    • Engler AJ, Carag-Krieger C, Johnson CP, Raab M, Tang HY, Speicher DW, et al. Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating. J Cell Sci. 2008;121:3794-802.
    • (2008) J Cell Sci. , vol.121 , pp. 3794-3802
    • Engler, A.J.1    Carag-Krieger, C.2    Johnson, C.P.3    Raab, M.4    Tang, H.Y.5    Speicher, D.W.6
  • 130
    • 79959909344 scopus 로고    scopus 로고
    • Controlled release of IGF-1 and HGF from a biodegradable polyurethane scaffold
    • Nelson DM, Baraniak PR, Ma Z, Guan J, Mason NS, Wagner WR. Controlled release of IGF-1 and HGF from a biodegradable polyurethane scaffold. Pharm Res. 2011;28:1282-93.
    • (2011) Pharm Res. , vol.28 , pp. 1282-1293
    • Nelson, D.M.1    Baraniak, P.R.2    Ma, Z.3    Guan, J.4    Mason, N.S.5    Wagner, W.R.6
  • 131
    • 79951802302 scopus 로고    scopus 로고
    • Differential roles of hypoxia inducible factor subunits in multipotential stromal cells under hypoxic condition
    • Tamama K, Kawasaki H, Kerpedjieva SS, Guan J, Ganju RK, Sen CK. Differential roles of hypoxia inducible factor subunits in multipotential stromal cells under hypoxic condition. J Cell Biochem. 2011;112:804-17.
    • (2011) J Cell Biochem. , vol.112 , pp. 804-817
    • Tamama, K.1    Kawasaki, H.2    Kerpedjieva, S.S.3    Guan, J.4    Ganju, R.K.5    Sen, C.K.6
  • 132
    • 84867460772 scopus 로고    scopus 로고
    • Creating 3D angiogenic growth factor gradients in fibrous constructs to guide fast angiogenesis
    • Guo X, Elliott CG, Li Z, Xu Y, Hamilton DW, Guan J. Creating 3D angiogenic growth factor gradients in fibrous constructs to guide fast angiogenesis. Biomacromolecules. 2012;13:3262-71.
    • (2012) Biomacromolecules. , vol.13 , pp. 3262-3271
    • Guo, X.1    Elliott, C.G.2    Li, Z.3    Xu, Y.4    Hamilton, D.W.5    Guan, J.6
  • 133
    • 84862139371 scopus 로고    scopus 로고
    • A thermosensitive hydrogel capable of releasing bFGF for enhanced differentiation of mesenchymal stem cell into cardiomyocytelike cells under ischemic conditions
    • Li Z, Guo X, Guan J. A thermosensitive hydrogel capable of releasing bFGF for enhanced differentiation of mesenchymal stem cell into cardiomyocytelike cells under ischemic conditions. Biomacromolecules. 2012;13:1956-64.
    • (2012) Biomacromolecules. , vol.13 , pp. 1956-1964
    • Li, Z.1    Guo, X.2    Guan, J.3
  • 134
    • 77956621279 scopus 로고    scopus 로고
    • Injectable, rapid gelling and highly flexible hydrogel composites as growth factor and cell carriers
    • Wang F, Li Z, Khan M, Tamama K, Kuppusamy P, Wagner WR, et al. Injectable, rapid gelling and highly flexible hydrogel composites as growth factor and cell carriers. Acta Biomater. 2010;6:1978-91.
    • (2010) Acta Biomater. , vol.6 , pp. 1978-1991
    • Wang, F.1    Li, Z.2    Khan, M.3    Tamama, K.4    Kuppusamy, P.5    Wagner, W.R.6
  • 135
    • 70349188341 scopus 로고    scopus 로고
    • Fabrication and characterization of prosurvival growth factor releasing, anisotropic scaffolds for enhanced mesenchymal stem cell survival/growth and orientation
    • Wang F, Li Z, Tamama K, Sen CK, Guan J. Fabrication and characterization of prosurvival growth factor releasing, anisotropic scaffolds for enhanced mesenchymal stem cell survival/growth and orientation. Biomacromolecules. 2009;10:2609-18.
    • (2009) Biomacromolecules. , vol.10 , pp. 2609-2618
    • Wang, F.1    Li, Z.2    Tamama, K.3    Sen, C.K.4    Guan, J.5
  • 136
    • 84862237077 scopus 로고    scopus 로고
    • An oxygen release system to augment cardiac progenitor cell survival and differentiation under hypoxic condition
    • Li Z, Guo X, Guan J. An oxygen release system to augment cardiac progenitor cell survival and differentiation under hypoxic condition. Biomaterials. 2012;33:5914-23.
    • (2012) Biomaterials. , vol.33 , pp. 5914-5923
    • Li, Z.1    Guo, X.2    Guan, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.