Targeted genome editing via CRISPR in the pathogen cryptococcus neoformans

PLoS ONE

Volumn 11, Issue 10, 2016, Pages

  Arras, Samantha D M ^a,b   Chua, Sheena M H ^a,b   Wizrah, Maha S I ^a,b   Faint, Joshua A ^a,b   Yap, Amy S ^a,b   Fraser, James A ^a,b  

^a The University of Queensland and QIMR Berghofer Medical Research Institute   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLASE; CAS9 NUCLEASE; GUIDE RNA; NUCLEASE; PHOSPHORIBOSYLAMINOAMIDAZOLE CARBOXYLASE; UNCLASSIFIED DRUG; VIRULENCE FACTOR; FUNGAL PROTEIN;

ADE2 GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL GENE; BACTERIAL GENOME; BACTERIAL GROWTH; BACTERIAL VIRULENCE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; FEMALE; GENE DELETION; GENE DISRUPTION; HOMOLOGOUS RECOMBINATION; MOUSE; NONHUMAN; STREPTOCOCCUS PYOGENES; ANIMAL; BAGG ALBINO MOUSE; CRISPR CAS SYSTEM; DISEASE MODEL; GENE EDITING; GENETICS; METABOLISM; MICROBIOLOGY; MORTALITY; PATHOGENICITY; PATHOLOGY; PHENOTYPE; SURVIVAL RATE; VIRULENCE;

ANIMALS; CRISPR-CAS SYSTEMS; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; DISEASE MODELS, ANIMAL; FEMALE; FUNGAL PROTEINS; GENE EDITING; MICE; MICE, INBRED BALB C; PHENOTYPE; RNA, GUIDE; SURVIVAL RATE; VIRULENCE;

EID: 84991247777     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0164322     Document Type: Article

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