Improvements to gene deletion in the fungal pathogen Cryptococcus neoformans: Absence of Ku proteins increases homologous recombination, and co-transformation of independent DNA molecules allows rapid complementation of deletion phenotypes

Fungal Genetics and Biology

Volumn 43, Issue 8, 2006, Pages 531-544

  Goins, Chelsey L ^a   Gerik, Kimberly J ^a   Lodge, Jennifer K ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CAP59; Homologous recombination; LAC1; Non homologous end joining

Indexed keywords

FUNGAL DNA; HETERODIMER; KU ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; DELETION MUTANT; FEMALE; FUNGAL GENETICS; FUNGAL STRAIN; GENE DELETION; GENE SEGREGATION; GENETIC COMPLEMENTATION; GENETIC TRANSFORMATION; GENETIC VARIABILITY; HOMOLOGOUS RECOMBINATION; MARKER GENE; MATING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PHENOTYPE; PREDICTION; PRIORITY JOURNAL; PROTEIN DEPLETION; WILD TYPE;

ANIMALS; CRYPTOCOCCUS NEOFORMANS; DNA-BINDING PROTEINS; FEMALE; FUNGAL PROTEINS; GENE DELETION; GENES, FUNGAL; GENETIC COMPLEMENTATION TEST; MICE; MICE, INBRED BALB C; PHENOTYPE; RECOMBINATION, GENETIC; SEQUENCE HOMOLOGY; TRANSFORMATION, GENETIC;

FILOBASIDIELLA NEOFORMANS; FUNGI;

EID: 33745727752     PISSN: 10871845     EISSN: 10960937     Source Type: Journal    
DOI: 10.1016/j.fgb.2006.02.007     Document Type: Article

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