Spray-dried mucoadhesives for intravesical drug delivery using N-acetylcysteine- and glutathione-glycol chitosan conjugates

Acta Biomaterialia

Volumn 43, Issue , 2016, Pages 170-184

  Denora, Nunzio ^a   Lopedota, Angela ^a   Perrone, Mara ^a   Laquintana, Valentino ^a   Iacobazzi, Rosa M ^a,b   Milella, Antonella ^a   Fanizza, Elisabetta ^a,c   Depalo, Nicoletta ^c   Cutrignelli, Annalisa ^a   Lopalco, Antonio ^d   Franco, Massimo ^a  

^a UNIVERSITY OF BARI   (Italy)

^b NATIONAL CANCER INSTITUTE GIOVANNI PAOLO II   (Italy)

^c CNR   (Italy)

^d UNIVERSITY OF KANSAS   (United States)

Author keywords

Bladder drug delivery; Glycol chitosan; Mucoadhesion; Oxidation; Spray drying

Indexed keywords

BODY FLUIDS; CATHETERS; CHITOSAN; CONTROLLED DRUG DELIVERY; GLYCOLS; PEPTIDES; SPRAY DRYING; TARGETED DRUG DELIVERY;

BLADDER DRUG DELIVERY; GLUTHATHIONE; GLYCOL CHITOSAN; MUCOADHESION; MUCOADHESIVES; N-ACETYLCYSTEINE; PROPERTY; SPRAY DRYING TECHNIQUE; SPRAY-DRYING; THIOL GROUPS;

OXIDATION;

ACETYLCYSTEINE; CHITOSAN; GLUTATHIONE; GLYCOL; THIOL GROUP; ADHESIVE AGENT; GLYCOL-CHITOSAN; MICROSPHERE; MUCIN; NANOPARTICLE; THIOL DERIVATIVE;

ARTICLE; BLADDER MUCOSA; CONTROLLED STUDY; DISULFIDE BOND; DRUG DELIVERY SYSTEM; DRUG SOLUBILITY; DRUG SYNTHESIS; MOLECULAR WEIGHT; MUCOADHESION; PH; PRIORITY JOURNAL; REACTION TIME; SIZE EXCLUSION CHROMATOGRAPHY; SPRAY DRYING; SURFACE PROPERTY; TURBIDIMETRY; URINE PH; X RAY PHOTOELECTRON SPECTROSCOPY; ANIMAL; CHEMISTRY; DESICCATION; INTRAVESICAL DRUG ADMINISTRATION; PHOTOMETRY; PIG; SOLUBILITY; STATIC ELECTRICITY; ULTRASTRUCTURE;

ACETYLCYSTEINE; ADHESIVES; ADMINISTRATION, INTRAVESICAL; ANIMALS; CHITOSAN; CHROMATOGRAPHY, GEL; DESICCATION; DRUG DELIVERY SYSTEMS; GLUTATHIONE; MICROSPHERES; MOLECULAR WEIGHT; MUCINS; NANOPARTICLES; NEPHELOMETRY AND TURBIDIMETRY; PHOTOELECTRON SPECTROSCOPY; SOLUBILITY; STATIC ELECTRICITY; SULFHYDRYL COMPOUNDS; SUS SCROFA;

EID: 84991098689     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2016.07.025     Document Type: Article

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