Potential for brain accessibility and analysis of stability of selected flavonoids in relation to neuroprotection in vitro

Brain Research

Volumn 1651, Issue , 2016, Pages 17-26

  Pogačnik, Lea ^a   Pirc, Katja ^a   Palmela, Inês ^c   Skrt, Mihaela ^a   Kwang, Kim S ^d   Brites, Dora ^c   Brito, Maria Alexandra ^c   Ulrih, Nataša Poklar ^a,b   Silva, Rui F M ^c  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b Centre of Excellence for Integrated Approaches in Chemistry and Biology of Proteins   (Slovenia)

^c RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Blood brain barrier; Flavonoids; Necrosis; Neuroprotection; synuclein fibrillation

Indexed keywords

ALPHA SYNUCLEIN; CYANIDIN 3 GLUCOSIDE; EPIGALLOCATECHIN GALLATE; NEUROPROTECTIVE AGENT; QUERCETIN; ANTHOCYANIN; ANTIOXIDANT; CATECHIN; CYANIDIN 3-O-GLUCOSIDE; FLAVONOID; GLUCOSIDE; RECOMBINANT PROTEIN; SNCA PROTEIN, HUMAN;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; DRUG STABILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; ROLE PLAYING; ANALOGS AND DERIVATIVES; ANIMAL; BRAIN; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; ENDOTHELIUM CELL; METABOLISM; NECROSIS; NERVE CELL; OXIDATIVE STRESS; PHYSIOLOGY; PRECLINICAL STUDY; PROTEIN MULTIMERIZATION; WISTAR RAT;

ALPHA-SYNUCLEIN; ANIMALS; ANTHOCYANINS; ANTIOXIDANTS; APOPTOSIS; BRAIN; CATECHIN; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; DRUG STABILITY; ENDOTHELIAL CELLS; FLAVONOIDS; GLUCOSIDES; HUMANS; NECROSIS; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PROTEIN MULTIMERIZATION; QUERCETIN; RATS, WISTAR; RECOMBINANT PROTEINS;

EID: 84990903127     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2016.09.020     Document Type: Article

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