-
1
-
-
0030882856
-
α-Synuclein in Lewy bodies
-
Spillantini, M. G., Schmidt, M. L., Lee, V. M., Trojanowski, J. Q., Jakes, R., and Goedert, M. (1997) α-Synuclein in Lewy bodies. Nature 388, 839-840
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
2
-
-
0032568534
-
α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies
-
DOI 10.1073/pnas.95.11.6469
-
Spillantini, M. G., Crowther, R. A., Jakes, R., Hasegawa, M., and Goedert, M. (1998) α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. U.S.A. 95, 6469-6473 (Pubitemid 28249037)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.11
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Hasegawa, M.4
Goedert, M.5
-
3
-
-
0030744876
-
Mutation in the α-synuclein gene identified in families with Parkinson's disease
-
DOI 10.1126/science.276.5321.2045
-
Polymeropoulos, M. H., Lavedan, C., Leroy, E., Ide, S. E., Dehejia, A., Dutra, A., Pike, B., Root, H., Rubenstein, J., Boyer, R., Stenroos, E. S., Chandrasekharappa, S., Athanassiadou, A., Papapetropoulos, T., Johnson, W. G., Lazzarini, A. M., Duvoisin, R. C., Di Iorio, G., Golbe, L. I., and Nussbaum, R. L. (1997) Mutation in the α-synuclein gene identified in families with Parkinson's disease. Science 276, 2045-2047 (Pubitemid 27443610)
-
(1997)
Science
, vol.276
, Issue.5321
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di, I.G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
4
-
-
0031787871
-
Accelerated in vitro fibril formation by a mutant α-synuclein linked to early-onset Parkinson disease
-
DOI 10.1038/3311
-
Conway, K. A., Harper, J. D., and Lansbury, P. T. (1998) Accelerated in vitro fibril formation by a mutant α-synuclein linked to early-onset Parkinson disease. Nat. Med. 4, 1318-1320 (Pubitemid 28512115)
-
(1998)
Nature Medicine
, vol.4
, Issue.11
, pp. 1318-1320
-
-
Conway, K.A.1
Harper, J.D.2
Lansbury, P.T.3
-
5
-
-
0033515471
-
Both familial Parkinson's disease mutations accelerate α-synuclein aggregation
-
Narhi, L., Wood, S. J., Steavenson, S., Jiang, Y., Wu, G. M., Anafi, D., Kaufman, S. A., Martin, F., Sitney, K., Denis, P., Louis, J. C., Wypych, J., Biere, A. L., and Citron, M. (1999) Both familial Parkinson's disease mutations accelerate α-synuclein aggregation. J. Biol. Chem. 274, 9843-9846
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 9843-9846
-
-
Narhi, L.1
Wood, S.J.2
Steavenson, S.3
Jiang, Y.4
Wu, G.M.5
Anafi, D.6
Kaufman, S.A.7
Martin, F.8
Sitney, K.9
Denis, P.10
Louis, J.C.11
Wypych, J.12
Biere, A.L.13
Citron, M.14
-
6
-
-
0037130174
-
Neurodegenerative disease: Amyloid pores from pathogenic mutations
-
Lashuel, H. A., Hartley, D., Petre, B. M., Walz, T., and Lansbury, P. T., Jr. (2002) Neurodegenerative disease: amyloid pores from pathogenic mutations. Nature 418, 291 (Pubitemid 34790672)
-
(2002)
Nature
, vol.418
, Issue.6895
, pp. 291
-
-
Lashuel, H.A.1
Hartley, D.2
Petre, B.M.3
Walz, T.4
Lansbury Jr., P.T.5
-
7
-
-
79952742454
-
In vivo demonstration that α-synuclein oligomers are toxic
-
Winner, B., Jappelli, R., Maji, S. K., Desplats, P. A., Boyer, L., Aigner, S., Hetzer, C., Loher, T., Vilar, M., Campioni, S., Tzitzilonis, C., Soragni, A., Jessberger, S., Mira, H., Consiglio, A., Pham, E., Masliah, E., Gage, F. H., and Riek, R. (2011) In vivo demonstration that α-synuclein oligomers are toxic. Proc. Natl. Acad. Sci. U.S.A. 108, 4194-4199
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 4194-4199
-
-
Winner, B.1
Jappelli, R.2
Maji, S.K.3
Desplats, P.A.4
Boyer, L.5
Aigner, S.6
Hetzer, C.7
Loher, T.8
Vilar, M.9
Campioni, S.10
Tzitzilonis, C.11
Soragni, A.12
Jessberger, S.13
Mira, H.14
Consiglio, A.15
Pham, E.16
Masliah, E.17
Gage, F.H.18
Riek, R.19
-
8
-
-
65249162241
-
Detection of elevated levels of soluble α-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies
-
Paleologou, K. E., Kragh, C. L., Mann, D. M., Salem, S. A., Al-Shami, R., Allsop, D., Hassan, A. H., Jensen, P. H., and El-Agnaf, O. M. (2009) Detection of elevated levels of soluble α-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies. Brain 132, 1093-1101
-
(2009)
Brain
, vol.132
, pp. 1093-1101
-
-
Paleologou, K.E.1
Kragh, C.L.2
Mann, D.M.3
Salem, S.A.4
Al-Shami, R.5
Allsop, D.6
Hassan, A.H.7
Jensen, P.H.8
El-Agnaf, O.M.9
-
9
-
-
78649990079
-
Detection of elevated levels of α-synuclein oligomers in CSF from patients with Parkinson disease
-
Tokuda, T., Qureshi, M. M., Ardah, M. T., Varghese, S., Shehab, S. A., Kasai, T., Ishigami, N., Tamaoka, A., Nakagawa, M., and El-Agnaf, O. M. (2010) Detection of elevated levels of α-synuclein oligomers in CSF from patients with Parkinson disease. Neurology 75, 1766-1772
-
(2010)
Neurology
, vol.75
, pp. 1766-1772
-
-
Tokuda, T.1
Qureshi, M.M.2
Ardah, M.T.3
Varghese, S.4
Shehab, S.A.5
Kasai, T.6
Ishigami, N.7
Tamaoka, A.8
Nakagawa, M.9
El-Agnaf, O.M.10
-
10
-
-
0035800097
-
Vesicle permeabilization by protofibrillar α-synuclein: Implications for the pathogenesis and treatment of Parkinson's disease
-
DOI 10.1021/bi0102398
-
Volles, M. J., Lee, S. J., Rochet, J. C., Shtilerman, M. D., Ding, T. T., Kessler, J. C., and Lansbury, P. T., Jr. (2001) Vesicle permeabilization by protofibrillar α-synuclein: implications for the pathogenesis and treatment of Parkinson's disease. Biochemistry 40, 7812-7819 (Pubitemid 32622972)
-
(2001)
Biochemistry
, vol.40
, Issue.26
, pp. 7812-7819
-
-
Volles, M.J.1
Lee, S.-J.2
Rochet, J.-C.3
Shtilerman, M.D.4
Ding, T.T.5
Kessler, J.C.6
Lansbury Jr., P.T.7
-
11
-
-
23044449398
-
Amyloid ion channels: A common structural link for protein-misfolding disease
-
DOI 10.1073/pnas.0502066102
-
Quist, A., Doudevski, I., Lin, H., Azimova, R., Ng, D., Frangione, B., Kagan, B., Ghiso, J., and Lal, R. (2005) Amyloid ion channels: a common structural link for protein-misfolding disease. Proc. Natl. Acad. Sci. U.S.A. 102, 10427-10432 (Pubitemid 41061570)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.30
, pp. 10427-10432
-
-
Quist, A.1
Doudevski, I.2
Lin, H.3
Azimova, R.4
Ng, D.5
Frangione, B.6
Kagan, B.7
Ghiso, J.8
Lal, R.9
-
12
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
DOI 10.1126/science.1079469
-
Kayed, R., Head, E., Thompson, J. L., McIntire, T. M., Milton, S. C., Cotman, C. W., and Glabe, C. G. (2003) Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300, 486-489 (Pubitemid 36444329)
-
(2003)
Science
, vol.300
, Issue.5618
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabel, C.G.7
-
13
-
-
44849087785
-
EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers
-
DOI 10.1038/nsmb.1437, PII NSMB1437
-
Ehrnhoefer, D. E., Bieschke, J., Boeddrich, A., Herbst, M., Masino, L., Lurz, R., Engemann, S., Pastore, A., and Wanker, E. E. (2008) EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers. Nat. Struct. Mol. Biol. 15, 558-566 (Pubitemid 351799141)
-
(2008)
Nature Structural and Molecular Biology
, vol.15
, Issue.6
, pp. 558-566
-
-
Ehrnhoefer, D.E.1
Bieschke, J.2
Boeddrich, A.3
Herbst, M.4
Masino, L.5
Lurz, R.6
Engemann, S.7
Pastore, A.8
Wanker, E.E.9
-
14
-
-
52049098478
-
Structural characteristics of α-synuclein oligomers stabilized by the flavonoid baicalein
-
Hong, D. P., Fink, A. L., and Uversky, V. N. (2008) Structural characteristics of α-synuclein oligomers stabilized by the flavonoid baicalein. J. Mol. Biol. 383, 214-223
-
(2008)
J. Mol. Biol.
, vol.383
, pp. 214-223
-
-
Hong, D.P.1
Fink, A.L.2
Uversky, V.N.3
-
15
-
-
0035834360
-
Kinetic stabilization of the α-synuclein protofibril by a dopamine-α-synuclein adduct
-
DOI 10.1126/science.1063522
-
Conway, K. A., Rochet, J. C., Bieganski, R. M., and Lansbury, P. T., Jr. (2001) Kinetic stabilization of the α-synuclein protofibril by a dopamine-α-synuclein adduct. Science 294, 1346-1349 (Pubitemid 33063102)
-
(2001)
Science
, vol.294
, Issue.5545
, pp. 1346-1349
-
-
Conway, K.A.1
Rochet, J.-C.2
Bieganski, R.M.3
Lansbury Jr., P.T.4
-
16
-
-
77952346781
-
EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity
-
Bieschke, J., Russ, J., Friedrich, R. P., Ehrnhoefer, D. E., Wobst, H., Neugebauer, K., and Wanker, E. E. (2010) EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity. Proc. Natl. Acad. Sci. U.S.A. 107, 7710-7715
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 7710-7715
-
-
Bieschke, J.1
Russ, J.2
Friedrich, R.P.3
Ehrnhoefer, D.E.4
Wobst, H.5
Neugebauer, K.6
Wanker, E.E.7
-
17
-
-
80555123045
-
Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications
-
Singh, B. N., Shankar, S., and Srivastava, R. K. (2011) Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications. Biochem. Pharmacol. 82, 1807-1821
-
(2011)
Biochem. Pharmacol.
, vol.82
, pp. 1807-1821
-
-
Singh, B.N.1
Shankar, S.2
Srivastava, R.K.3
-
18
-
-
3042547187
-
The flavonoid baicalein inhibits fibrillation of α-synuclein and disaggregates existing fibrils
-
DOI 10.1074/jbc.M403129200
-
Zhu, M., Rajamani, S., Kaylor, J., Han, S., Zhou, F., and Fink, A. L. (2004) The flavonoid baicalein inhibits fibrillation of α-synuclein and disaggregates existing fibrils. J. Biol. Chem. 279, 26846-26857 (Pubitemid 38812518)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.26
, pp. 26846-26857
-
-
Zhu, M.1
Rajamani, S.2
Kaylor, J.3
Han, S.4
Zhou, F.5
Fink, A.L.6
-
19
-
-
4344650564
-
Dopamine and L-dopa disaggregate amyloid fibrils: Implications for Parkinson's and Alzheimer's disease
-
DOI 10.1096/fj.03-0770fje
-
Li, J., Zhu, M., Manning-Bog, A. B., Di Monte, D. A., and Fink, A. L. (2004) Dopamine and L-dopa disaggregate amyloid fibrils: implications for Parkinson's and Alzheimer's disease. FASEB J. 18, 962-964 (Pubitemid 39561492)
-
(2004)
FASEB Journal
, vol.18
, Issue.9
, pp. 962-964
-
-
Li, J.1
Zhu, M.2
Manning-Bog, A.B.3
Di, M.D.A.4
Fink, A.L.5
-
20
-
-
77955946838
-
Effects of various flavonoids on the α-synuclein fibrillation process
-
Meng, X., Munishkina, L. A., Fink, A. L., and Uversky, V. N. (2010) Effects of various flavonoids on the α-synuclein fibrillation process. Parkinsons Dis. 2010, 650794
-
(2010)
Parkinsons Dis.
, vol.2010
, pp. 650794
-
-
Meng, X.1
Munishkina, L.A.2
Fink, A.L.3
Uversky, V.N.4
-
21
-
-
33748744375
-
Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models
-
DOI 10.1093/hmg/ddl210
-
Ehrnhoefer, D. E., Duennwald, M., Markovic, P., Wacker, J. L., Engemann, S., Roark, M., Legleiter, J., Marsh, J. L., Thompson, L. M., Lindquist, S., Muchowski, P. J., and Wanker, E. E. (2006) Green tea (-)-epigallocatechin- gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models. Hum. Mol. Genet. 15, 2743-2751 (Pubitemid 44400401)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.18
, pp. 2743-2751
-
-
Ehrnhoefer, D.E.1
Duennwald, M.2
Markovic, P.3
Wacker, J.L.4
Engemann, S.5
Roark, M.6
Legleiter, J.7
Marsh, J.L.8
Thompson, L.M.9
Lindquist, S.10
Muchowski, P.J.11
Wanker, E.E.12
-
22
-
-
77956595088
-
The flavanol (-)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP-induced toxicity
-
Meng, F., Abedini, A., Plesner, A., Verchere, C. B., and Raleigh, D. P. (2010) The flavanol (-)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP-induced toxicity. Biochemistry 49, 8127-8133
-
(2010)
Biochemistry
, vol.49
, pp. 8127-8133
-
-
Meng, F.1
Abedini, A.2
Plesner, A.3
Verchere, C.B.4
Raleigh, D.P.5
-
23
-
-
79960910835
-
Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation
-
Ferreira, N., Saraiva, M. J., and Amleida, M. R. (2011) Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation. FEBS Lett. 585, 2424-2430
-
(2011)
FEBS Lett.
, vol.585
, pp. 2424-2430
-
-
Ferreira, N.1
Saraiva, M.J.2
Amleida, M.R.3
-
24
-
-
77954572992
-
Inhibition by flavonoids of amyloid-like fibril formation by Plasmodium falciparum merozoite surface protein 2
-
Chandrashekaran, I. R., Adda, C. G., MacRaild, C. A., Anders, R. F., and Norton, R. S. (2010) Inhibition by flavonoids of amyloid-like fibril formation by Plasmodium falciparum merozoite surface protein 2. Biochemistry 49, 5899-5908
-
(2010)
Biochemistry
, vol.49
, pp. 5899-5908
-
-
Chandrashekaran, I.R.1
Adda, C.G.2
MacRaild, C.A.3
Anders, R.F.4
Norton, R.S.5
-
25
-
-
69349098271
-
(-)-Epigallocatechin-3-gallate (EGCG) maintains κ-casein in its pre-fibrillar state without redirecting its aggregation pathway
-
Hudson, S. A., Ecroyd, H., Dehle, F. C., Musgrave, I. F., and Carver, J. A. (2009) (-)-Epigallocatechin-3-gallate (EGCG) maintains κ-casein in its pre-fibrillar state without redirecting its aggregation pathway. J. Mol. Biol. 392, 689-700
-
(2009)
J. Mol. Biol.
, vol.392
, pp. 689-700
-
-
Hudson, S.A.1
Ecroyd, H.2
Dehle, F.C.3
Musgrave, I.F.4
Carver, J.A.5
-
26
-
-
73549103148
-
A synergistic small-molecule combination directly eradicates diverse prion strain structures
-
Roberts, B. E., Duennwald, M. L., Wang, H., Chung, C., Lopreiato, N. P., Sweeny, E. A., Knight, M. N., and Shorter, J. (2009) A synergistic small-molecule combination directly eradicates diverse prion strain structures. Nat. Chem. Biol. 5, 936-946
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 936-946
-
-
Roberts, B.E.1
Duennwald, M.L.2
Wang, H.3
Chung, C.4
Lopreiato, N.P.5
Sweeny, E.A.6
Knight, M.N.7
Shorter, J.8
-
27
-
-
84878234966
-
Toward the molecular mechanism(s) by which EGCG treatment remodels mature amyloid fibrils
-
Palhano, F. L., Lee, J., Grimster, N. P., and Kelly, J. W. (2013) Toward the molecular mechanism(s) by which EGCG treatment remodels mature amyloid fibrils. J. Am. Chem. Soc. 135, 7503-7510
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 7503-7510
-
-
Palhano, F.L.1
Lee, J.2
Grimster, N.P.3
Kelly, J.W.4
-
28
-
-
54849423681
-
Inhibition of α-synuclein fibrillization by dopamine is mediated by interactions with five C-terminal residues and with E83 in the NAC region
-
Herrera, F. E., Chesi, A., Paleologou, K. E., Schmid, A., Munoz, A., Vendruscolo, M., Gustincich, S., Lashuel, H. A., and Carloni, P. (2008) Inhibition of α-synuclein fibrillization by dopamine is mediated by interactions with five C-terminal residues and with E83 in the NAC region. PLoS One 3, e3394
-
(2008)
PLoS One
, vol.3
-
-
Herrera, F.E.1
Chesi, A.2
Paleologou, K.E.3
Schmid, A.4
Munoz, A.5
Vendruscolo, M.6
Gustincich, S.7
Lashuel, H.A.8
Carloni, P.9
-
29
-
-
20444401187
-
Reversible inhibition of α-synuclein fibrillization by dopaminochrome-mediated conformational alterations
-
DOI 10.1074/jbc.M412621200
-
Norris, E. H., Giasson, B. I., Hodara, R., Xu, S., Trojanowski, J. Q., Ischiropoulos, H., and Lee, V. M. (2005) Reversible inhibition of α-synuclein fibrillization by dopaminochrome-mediated conformational alterations. J. Biol. Chem. 280, 21212-21219 (Pubitemid 40805683)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.22
, pp. 21212-21219
-
-
Norris, E.H.1
Giasson, B.I.2
Hodara, R.3
Xu, S.4
Trojanowski, J.Q.5
Ischiropoulos, H.6
Lee, V.M.-Y.7
-
30
-
-
79952748803
-
Low-resolution structure of a vesicle disrupting α-synuclein oligomer that accumulates during fibrillation
-
Giehm, L., Svergun, D. I., Otzen, D. E., and Vestergaard, B. (2011) Low-resolution structure of a vesicle disrupting α-synuclein oligomer that accumulates during fibrillation. Proc. Natl. Acad. Sci. U.S.A. 108, 3246-3251
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 3246-3251
-
-
Giehm, L.1
Svergun, D.I.2
Otzen, D.E.3
Vestergaard, B.4
-
31
-
-
84865426796
-
Molecular composition of sub-stoichiometrically labeled α-synuclein oligomers determined by single-molecule photobleaching
-
Zijlstra, N., Blum, C., Segers-Nolten, I. M., Claessens, M. M., and Subramaniam, V. (2012) Molecular composition of sub-stoichiometrically labeled α-synuclein oligomers determined by single-molecule photobleaching. Angew. Chem. Int. Ed. Engl. 51, 8821-8824
-
(2012)
Angew. Chem. Int. Ed. Engl.
, vol.51
, pp. 8821-8824
-
-
Zijlstra, N.1
Blum, C.2
Segers-Nolten, I.M.3
Claessens, M.M.4
Subramaniam, V.5
-
32
-
-
84896265204
-
The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation
-
Lorenzen, N., Nielsen, S. B., Buell, A. K., Kaspersen, J. D., Arosio, P., Vad, B. S., Paslawski, W., Christiansen, G., Valnickova-Hansen, Z., Andreasen, M., Enghild, J. J., Pedersen, J. S., Dobson, C. M., Knowles, T. P., and Otzen, D. E. (2014) The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation. J. Am. Chem. Soc. 136, 3859-3868
-
(2014)
J. Am. Chem. Soc.
, vol.136
, pp. 3859-3868
-
-
Lorenzen, N.1
Nielsen, S.B.2
Buell, A.K.3
Kaspersen, J.D.4
Arosio, P.5
Vad, B.S.6
Paslawski, W.7
Christiansen, G.8
Valnickova-Hansen, Z.9
Andreasen, M.10
Enghild, J.J.11
Pedersen, J.S.12
Dobson, C.M.13
Knowles, T.P.14
Otzen, D.E.15
-
33
-
-
54849417407
-
Membrane binding of oligomeric α-synuclein depends on bilayer charge and packing
-
van Rooijen, B. D., Claessens, M. M., and Subramaniam, V. (2008) Membrane binding of oligomeric α-synuclein depends on bilayer charge and packing. FEBS Lett. 582, 3788-3792
-
(2008)
FEBS Lett.
, vol.582
, pp. 3788-3792
-
-
Van Rooijen, B.D.1
Claessens, M.M.2
Subramaniam, V.3
-
34
-
-
84892794505
-
The N terminus of α-synuclein is essential for both monomeric and oligomeric interactions with membranes
-
Lorenzen, N., Lemminger, L., Pedersen, J. N., Nielsen, S. B., and Otzen, D. E. (2014) The N terminus of α-synuclein is essential for both monomeric and oligomeric interactions with membranes. FEBS Lett. 588, 497-502
-
(2014)
FEBS Lett.
, vol.588
, pp. 497-502
-
-
Lorenzen, N.1
Lemminger, L.2
Pedersen, J.N.3
Nielsen, S.B.4
Otzen, D.E.5
-
35
-
-
65549114936
-
Lipid bilayer disruption by oligomeric α-synuclein depends on bilayer charge and accessibility of the hydrophobic core
-
van Rooijen, B. D., Claessens, M. M., and Subramaniam, V. (2009) Lipid bilayer disruption by oligomeric α-synuclein depends on bilayer charge and accessibility of the hydrophobic core. Biochim. Biophys. Acta 1788, 1271-1278
-
(2009)
Biochim. Biophys. Acta
, vol.1788
, pp. 1271-1278
-
-
Van Rooijen, B.D.1
Claessens, M.M.2
Subramaniam, V.3
-
36
-
-
70449626845
-
Tryptophan fluorescence reveals structural features of α-synuclein oligomers
-
van Rooijen, B. D., van Leijenhorst-Groener, K. A., Claessens, M. M., and Subramaniam, V. (2009) Tryptophan fluorescence reveals structural features of α-synuclein oligomers. J. Mol. Biol. 394, 826-833
-
(2009)
J. Mol. Biol.
, vol.394
, pp. 826-833
-
-
Van Rooijen, B.D.1
Van Leijenhorst-Groener, K.A.2
Claessens, M.M.3
Subramaniam, V.4
-
37
-
-
84876891740
-
α-Synuclein oligomers: An amyloid pore? Insights into mechanisms of α-synuclein oligomer-lipid interactions
-
Stöckl, M. T., Zijlstra, N., and Subramaniam, V. (2013) α-Synuclein oligomers: an amyloid pore? Insights into mechanisms of α-synuclein oligomer-lipid interactions. Mol. Neurobiol. 47, 613-621
-
(2013)
Mol. Neurobiol.
, vol.47
, pp. 613-621
-
-
Stöckl, M.T.1
Zijlstra, N.2
Subramaniam, V.3
-
38
-
-
78650763561
-
Membrane permeabilization by oligomeric α-synuclein: In search of the mechanism
-
van Rooijen B. D., Claessens, M. M., Subramaniam V. (2010) Membrane permeabilization by oligomeric α-synuclein: In search of the mechanism. PLoS One 5, e14292
-
(2010)
PLoS One
, vol.5
-
-
Van Rooijen, B.D.1
Claessens, M.M.2
Subramaniam, V.3
-
39
-
-
0030017964
-
OLN-93: A new permanent oligodendroglia cell line derived from primary rat brain glial cultures
-
DOI 10.1002/(SICI)1097-4547(19960715)45:2<161::AID
-
Richter-Landsberg, C., and Heinrich, M. (1996) OLN-93: a new permanent oligodendroglia cell line derived from primary rat brain glial cultures. J. Neurosci. Res. 45, 161-173 (Pubitemid 26257317)
-
(1996)
Journal of Neuroscience Research
, vol.45
, Issue.2
, pp. 161-173
-
-
Richter-Landsberg, C.1
Heinrich, M.2
-
41
-
-
0032826460
-
Two-photon fluorescence microscopy observation of shape changes at the phase transition in phospholipid giant unilamellar vesicles
-
Bagatolli, L. A., and Gratton, E. (1999) Two-photon fluorescence microscopy observation of shape changes at the phase transition in phospholipid giant unilamellar vesicles. Biophys. J. 77, 2090-2101 (Pubitemid 29463170)
-
(1999)
Biophysical Journal
, vol.77
, Issue.4
, pp. 2090-2101
-
-
Bagatolli, L.A.1
Gratton, E.2
-
42
-
-
0029400480
-
NMRPipe: A multidimensional spectral processing system based on UNIX pipes
-
Delaglio, F., Grzesiek, S., Vuister, G. W., Zhu, G., Pfeifer, J., and Bax, A. (1995) NMRPipe: a multidimensional spectral processing system based on UNIX pipes. J. Biomol. NMR 6, 277-293
-
(1995)
J. Biomol. NMR
, vol.6
, pp. 277-293
-
-
Delaglio, F.1
Grzesiek, S.2
Vuister, G.W.3
Zhu, G.4
Pfeifer, J.5
Bax, A.6
-
43
-
-
3442880149
-
A flux- and background-optimized version of the NanoSTAR small-angle x-ray scattering camera for solution scattering
-
Pedersen, J. S. (2004) A flux- and background-optimized version of the NanoSTAR small-angle x-ray scattering camera for solution scattering. J. Appl. Crystallogr. 37, 369-380
-
(2004)
J. Appl. Crystallogr.
, vol.37
, pp. 369-380
-
-
Pedersen, J.S.1
-
44
-
-
0001035402
-
Scattering form factor of block copolymer micelles
-
Pedersen, J. S., and Gerstenberg, M. C. (1996) Scattering form factor of block copolymer micelles. Macromolecules 29, 1363-1365
-
(1996)
Macromolecules
, vol.29
, pp. 1363-1365
-
-
Pedersen, J.S.1
Gerstenberg, M.C.2
-
45
-
-
0001498978
-
La diffraction des rayons X aux tres petits angles; application a l'etude de phenomenes ultramicroscopiques
-
Guinier, A. (1939) La diffraction des rayons X aux tres petits angles; application a l'etude de phenomenes ultramicroscopiques. Ann. Phys. 12, 161-237
-
(1939)
Ann. Phys.
, vol.12
, pp. 161-237
-
-
Guinier, A.1
-
46
-
-
33644606089
-
Molecular-weight determination by light scattering
-
Debye, P. (1947) Molecular-weight determination by light scattering. J. Phys. Colloid. Chem. 51, 18-32
-
(1947)
J. Phys. Colloid. Chem.
, vol.51
, pp. 18-32
-
-
Debye, P.1
-
47
-
-
84895775448
-
Characterizing the dynamics of α-synuclein oligomers using hydrogen/deuterium exchange monitored by mass spectrometry
-
Mysling, S., Betzer, C., Jensen, P. H., and Jorgensen, T. J. (2013) Characterizing the dynamics of α-synuclein oligomers using hydrogen/deuterium exchange monitored by mass spectrometry. Biochemistry 52, 9097-9103
-
(2013)
Biochemistry
, vol.52
, pp. 9097-9103
-
-
Mysling, S.1
Betzer, C.2
Jensen, P.H.3
Jorgensen, T.J.4
-
48
-
-
84904515491
-
Co-existence of two different α-synuclein oligomers with different core structures determined by hydrogen/deuterium exchange mass spectrometry
-
10.1002/anie.201400491
-
Paslawski, W., Mysling, S., Thomsen, K., Jørgensen, T. J. D., and Otzen, D. E. (2014) Co-existence of two different α-synuclein oligomers with different core structures determined by hydrogen/deuterium exchange mass spectrometry. Angew. Chem. Int. Ed. Engl. 10.1002/anie.201400491
-
(2014)
Angew. Chem. Int. Ed. Engl.
-
-
Paslawski, W.1
Mysling, S.2
Thomsen, K.3
Jørgensen, T.J.D.4
Otzen, D.E.5
-
49
-
-
0034773940
-
Solvent-induced collapse of α-synuclein and acid-denatured cytochrome c
-
DOI 10.1110/ps.24301
-
Morar, A. S., Olteanu, A., Young, G. B., and Pielak, G. J. (2001) Solvent-induced collapse of α-synuclein and acid-denatured cytochrome c. Protein Sci. 10, 2195-2199 (Pubitemid 32988636)
-
(2001)
Protein Science
, vol.10
, Issue.11
, pp. 2195-2199
-
-
Morar, A.S.1
Olteanu, A.2
Young, G.B.3
Pielak, G.J.4
-
50
-
-
67649344732
-
The influence of vesicle size and composition on α-synuclein structure and stability
-
Kjaer, L., Giehm, L., Heimburg, T., and Otzen, D. (2009) The influence of vesicle size and composition on α-synuclein structure and stability. Biophys. J. 96, 2857-2870
-
(2009)
Biophys. J.
, vol.96
, pp. 2857-2870
-
-
Kjaer, L.1
Giehm, L.2
Heimburg, T.3
Otzen, D.4
|