Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma Cells

Immunity

Volumn 45, Issue 1, 2016, Pages 60-73

  Lam, Wing Y ^a   Becker, Amy M ^a,e   Kennerly, Krista M ^a   Wong, Rachel ^a   Curtis, Jonathan D ^a,f   Llufrio, Elizabeth M ^a   McCommis, Kyle S ^a   Fahrmann, Johannes ^b,g   Pizzato, Hannah A ^a   Nunley, Ryan M ^c   Lee, Jieun ^d   Wolfgang, Michael J ^d   Patti, Gary J ^a   Finck, Brian N ^a   Pearce, Erika L ^a   Bhattacharya, Deepta ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BARNES JEWISH HOSPITAL   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e BOSTON CHILDREN S HOSPITAL   (United States)

^f MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^g UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 CYANO 3 (1 PHENYLINDOL 3 YL)ACRYLIC ACID; 6 PHOSPHOFRUCTOKINASE; ANTIMYCIN A1; ASPARTIC ACID; ETOMOXIR; FRUCTOSE 6 PHOSPHATE; GLUCOSE; OLIGOMYCIN; PROPIONIC ACID; PYRUVATE CARBOXYLASE; PYRUVIC ACID; ROTENONE; TAMOXIFEN; IMMUNOGLOBULIN; PCSK2 PROTEIN, MOUSE; PROPROTEIN CONVERTASE 2;

ANIMAL CELL; ANTIBODY PRODUCTION; ANTIBODY SECRETING CELL; ARTICLE; BONE MARROW CELL; BREATHING; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCOSE TRANSPORT; GLYCOLYSIS; GLYCOSYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LONG TERM SURVIVAL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; OXYGEN CONSUMPTION; PLASMA CELL; PRIORITY JOURNAL; RNA SEQUENCE; SPLEEN CELL; ACTIVE TRANSPORT; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; CELL RESPIRATION; GENETICS; IMMUNOGLOBULIN PRODUCING CELL; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGICAL STRESS;

ANIMALS; ANTIBODY-PRODUCING CELLS; BIOLOGICAL TRANSPORT, ACTIVE; CELL RESPIRATION; CELLS, CULTURED; GLUCOSE; GLYCOSYLATION; HUMANS; IMMUNOGLOBULINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; PLASMA CELLS; PROPROTEIN CONVERTASE 2; PYRUVIC ACID; STRESS, PHYSIOLOGICAL;

EID: 84990852810     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2016.06.011     Document Type: Article

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