-
1
-
-
79751477368
-
A glimpse of various pathogenetic mechanisms of diabetic nephropathy
-
Kanwar, Y. S., Sun, L., Xie, P., Liu, F. Y. & Chen, S. A glimpse of various pathogenetic mechanisms of diabetic nephropathy. Annu. Rev. Pathol. 6, 395-423 (2011).
-
(2011)
Annu. Rev. Pathol.
, vol.6
, pp. 395-423
-
-
Kanwar, Y.S.1
Sun, L.2
Xie, P.3
Liu, F.Y.4
Chen, S.5
-
2
-
-
84945444690
-
MicroRNAs in diabetic nephropathy: Functions, biomarkers, and therapeutic targets
-
Kato, M. & Natarajan, R. MicroRNAs in diabetic nephropathy: functions, biomarkers, and therapeutic targets. Ann. N. Y. Acad. Sci. 1353, 72-88 (2015).
-
(2015)
Ann. N. Y. Acad. Sci.
, vol.1353
, pp. 72-88
-
-
Kato, M.1
Natarajan, R.2
-
3
-
-
0029076281
-
Hyperglycemia and diabetic kidney disease. The case for transforming growth factor-beta as a key mediator
-
Sharma, K. & Ziyadeh, F. N. Hyperglycemia and diabetic kidney disease. The case for transforming growth factor-beta as a key mediator. Diabetes 44, 1139-1146 (1995).
-
(1995)
Diabetes
, vol.44
, pp. 1139-1146
-
-
Sharma, K.1
Ziyadeh, F.N.2
-
4
-
-
0034608948
-
Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice
-
Ziyadeh, F. N. et al. Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice. Proc. Natl Acad. Sci. USA 97, 8015-8020 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 8015-8020
-
-
Ziyadeh, F.N.1
-
5
-
-
0027479442
-
Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathy
-
Yamamoto, T., Nakamura, T., Noble, N. A., Ruoslahti, E. & Border, W. A. Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathy. Proc. Natl Acad. Sci. USA 90, 1814-1818 (1993).
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 1814-1818
-
-
Yamamoto, T.1
Nakamura, T.2
Noble, N.A.3
Ruoslahti, E.4
Border, W.A.5
-
6
-
-
84906939393
-
Diabetic nephropathy-emerging epigenetic mechanisms
-
Kato, M. & Natarajan, R. Diabetic nephropathy-emerging epigenetic mechanisms. Nat. Rev. Nephrol. 10, 517-530 (2014).
-
(2014)
Nat. Rev. Nephrol.
, vol.10
, pp. 517-530
-
-
Kato, M.1
Natarajan, R.2
-
7
-
-
84902195666
-
Molecular mechanisms of diabetic kidney disease
-
Reidy, K., Kang, H. M., Hostetter, T. & Susztak, K. Molecular mechanisms of diabetic kidney disease. J. Clin. Invest. 124, 2333-2340 (2014).
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 2333-2340
-
-
Reidy, K.1
Kang, H.M.2
Hostetter, T.3
Susztak, K.4
-
8
-
-
0030604542
-
TGFbeta signaling: Receptors, transducers, and Mad proteins
-
Massague, J. TGFbeta signaling: receptors, transducers, and Mad proteins. Cell 85, 947-950 (1996).
-
(1996)
Cell
, vol.85
, pp. 947-950
-
-
Massague, J.1
-
9
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel, D. P. MicroRNAs: target recognition and regulatory functions. Cell 136, 215-233 (2009).
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
10
-
-
84924908396
-
MicroRNAs in kidney physiology and disease
-
Trionfini, P., Benigni, A. & Remuzzi, G. MicroRNAs in kidney physiology and disease. Nat. Rev. Nephrol. 11, 23-33 (2015).
-
(2015)
Nat. Rev. Nephrol.
, vol.11
, pp. 23-33
-
-
Trionfini, P.1
Benigni, A.2
Remuzzi, G.3
-
11
-
-
67650085171
-
TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN
-
Kato, M. et al. TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN. Nat. Cell Biol. 11, 881-889 (2009).
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 881-889
-
-
Kato, M.1
-
12
-
-
84857979740
-
Inhibiting microRNA-192 ameliorates renal fibrosis in diabetic nephropathy
-
Putta, S. et al. Inhibiting microRNA-192 ameliorates renal fibrosis in diabetic nephropathy. J. Am. Soc. Nephrol. 23, 458-469 (2012).
-
(2012)
J. Am. Soc. Nephrol.
, vol.23
, pp. 458-469
-
-
Putta, S.1
-
13
-
-
28444469246
-
Silencing of microRNAs in vivo with 'antagomirs'
-
Krutzfeldt, J. et al. Silencing of microRNAs in vivo with 'antagomirs'. Nature 438, 685-689 (2005).
-
(2005)
Nature
, vol.438
, pp. 685-689
-
-
Krutzfeldt, J.1
-
14
-
-
84903717510
-
Development of microRNA therapeutics is coming of age
-
van Rooij, E. & Kauppinen, S. Development of microRNA therapeutics is coming of age. EMBO Mol. Med. 6, 851-864 (2014).
-
(2014)
EMBO Mol. Med.
, vol.6
, pp. 851-864
-
-
Van Rooij, E.1
Kauppinen, S.2
-
15
-
-
84869120708
-
Discovering the first microRNA-targeted drug
-
Lindow, M. & Kauppinen, S. Discovering the first microRNA-targeted drug. J. Cell Biol. 199, 407-412 (2012).
-
(2012)
J. Cell Biol.
, vol.199
, pp. 407-412
-
-
Lindow, M.1
Kauppinen, S.2
-
16
-
-
80052248898
-
A microRNA circuit mediates transforming growth factor-beta1 autoregulation in renal glomerular mesangial cells
-
Kato, M. et al. A microRNA circuit mediates transforming growth factor-beta1 autoregulation in renal glomerular mesangial cells. Kidney Int. 80, 358-368 (2011).
-
(2011)
Kidney Int.
, vol.80
, pp. 358-368
-
-
Kato, M.1
-
17
-
-
84884793994
-
Transforming growth factor-beta-induced cross talk between p53 and a microRNA in the pathogenesis of diabetic nephropathy
-
Deshpande, S. D. et al. Transforming growth factor-beta-induced cross talk between p53 and a microRNA in the pathogenesis of diabetic nephropathy. Diabetes 62, 3151-3162 (2013).
-
(2013)
Diabetes
, vol.62
, pp. 3151-3162
-
-
Deshpande, S.D.1
-
18
-
-
79953215711
-
MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy
-
Long, J., Wang, Y., Wang, W., Chang, B. H. & Danesh, F. R. MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy. J. Biol. Chem. 286, 11837-11848 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 11837-11848
-
-
Long, J.1
Wang, Y.2
Wang, W.3
Chang, B.H.4
Danesh, F.R.5
-
19
-
-
84904726017
-
MIR-135a promotes renal fibrosis in diabetic nephropathy by regulating TRPC1
-
He, F. et al. MiR-135a promotes renal fibrosis in diabetic nephropathy by regulating TRPC1. Diabetologia 57, 1726-1736 (2014).
-
(2014)
Diabetologia
, vol.57
, pp. 1726-1736
-
-
He, F.1
-
20
-
-
84878269299
-
MIR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes
-
Zhong, X. et al. miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes. Diabetologia 56, 663-674 (2013).
-
(2013)
Diabetologia
, vol.56
, pp. 663-674
-
-
Zhong, X.1
-
21
-
-
84863116324
-
MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways
-
Chau, B. N. et al. MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways. Sci. Transl. Med. 4, 121ra118 (2012).
-
(2012)
Sci. Transl. Med.
, vol.4
, pp. 121ra118
-
-
Chau, B.N.1
-
22
-
-
84860849258
-
Small RNA sequencing reveals microRNAs that modulate angiotensin II effects in vascular smooth muscle cells
-
Jin, W. et al. Small RNA sequencing reveals microRNAs that modulate angiotensin II effects in vascular smooth muscle cells. J. Biol. Chem. 287, 15672-15683 (2012).
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 15672-15683
-
-
Jin, W.1
-
23
-
-
84891856209
-
Epigenetic regulation of the DLK1-MEG3 microRNA cluster in human type 2 diabetic islets
-
Kameswaran, V. et al. Epigenetic regulation of the DLK1-MEG3 microRNA cluster in human type 2 diabetic islets. Cell Metab. 19, 135-145 (2014).
-
(2014)
Cell Metab.
, vol.19
, pp. 135-145
-
-
Kameswaran, V.1
-
24
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian, A. et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl Acad. Sci. USA 102, 15545-15550 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
-
25
-
-
79953748673
-
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
-
Wang, K. C. et al. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature 472, 120-124 (2011).
-
(2011)
Nature
, vol.472
, pp. 120-124
-
-
Wang, K.C.1
-
26
-
-
57349186092
-
MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy
-
Wang, Q. et al. MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy. FASEB J 22, 4126-4135 (2008).
-
(2008)
FASEB J
, vol.22
, pp. 4126-4135
-
-
Wang, Q.1
-
27
-
-
78650470110
-
MicroRNA-target pairs in human renal epithelial cells treated with transforming growth factor beta 1: A novel role of MIR-382
-
Kriegel, A. J. et al. MicroRNA-target pairs in human renal epithelial cells treated with transforming growth factor beta 1: a novel role of miR-382. Nucleic Acids Res. 38, 8338-8347 (2010).
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 8338-8347
-
-
Kriegel, A.J.1
-
28
-
-
84878912696
-
TGF-beta induces acetylation of chromatin and of Ets-1 to alleviate repression of MIR-192 in diabetic nephropathy
-
Kato, M. et al. TGF-beta induces acetylation of chromatin and of Ets-1 to alleviate repression of miR-192 in diabetic nephropathy. Sci. Signal. 6, ra43 (2013).
-
(2013)
Sci. Signal.
, vol.6
, pp. ra43
-
-
Kato, M.1
-
29
-
-
84886396594
-
Role of microRNA 1207-5P and its host gene, the long non-coding RNA Pvt1, as mediators of extracellular matrix accumulation in the kidney: Implications for diabetic nephropathy
-
Alvarez, M. L., Khosroheidari, M., Eddy, E. & Kiefer, J. Role of microRNA 1207-5P and its host gene, the long non-coding RNA Pvt1, as mediators of extracellular matrix accumulation in the kidney: implications for diabetic nephropathy. PLoS ONE 8, e77468 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e77468
-
-
Alvarez, M.L.1
Khosroheidari, M.2
Eddy, E.3
Kiefer, J.4
-
30
-
-
84943634487
-
Transcription factor hepatocyte nuclear factor-1b (HNF-1b) regulates microRNA-200 expression through a long noncoding RNA
-
Hajarnis, S. S. et al. Transcription factor hepatocyte nuclear factor-1b (HNF-1b) regulates microRNA-200 expression through a long noncoding RNA. J. Biol. Chem. 290, 24793-24805 (2015).
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 24793-24805
-
-
Hajarnis, S.S.1
-
31
-
-
0037245474
-
Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein CUGBP2
-
Mukhopadhyay, D., Houchen, C.W., Kennedy, S., Dieckgraefe, B. K. & Anant, S. Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2. Mol. Cell 11, 113-126 (2003).
-
(2003)
Mol. Cell
, vol.11
, pp. 113-126
-
-
Mukhopadhyay, D.1
Houchen, C.W.2
Kennedy, S.3
Dieckgraefe, B.K.4
Anant, S.5
-
32
-
-
62649086993
-
Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels
-
Fiore, R. et al. Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels. EMBO J. 28, 697-710 (2009).
-
(2009)
EMBO J.
, vol.28
, pp. 697-710
-
-
Fiore, R.1
-
33
-
-
66449123316
-
The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins
-
Lazzaretti, D., Tournier, I. & Izaurralde, E. The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins. RNA 15, 1059-1066 (2009).
-
(2009)
RNA
, vol.15
, pp. 1059-1066
-
-
Lazzaretti, D.1
Tournier, I.2
Izaurralde, E.3
-
34
-
-
77951978351
-
Mitotic cell-cycle progression is regulated by CPEB1 and CPEB4-dependent translational control
-
Novoa, I., Gallego, J., Ferreira, P. G. & Mendez, R. Mitotic cell-cycle progression is regulated by CPEB1 and CPEB4-dependent translational control. Nat. Cell Biol. 12, 447-456 (2010).
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 447-456
-
-
Novoa, I.1
Gallego, J.2
Ferreira, P.G.3
Mendez, R.4
-
35
-
-
1542297742
-
Identification of a target RNA motif for RNA-binding protein HuR
-
de Silanes, I. L., Zhan, M., Lal, A., Yang, X. & Gorospe, M. Identification of a target RNA motif for RNA-binding protein HuR. Proc. Natl Acad. Sci. USA 101, 2987-2992 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 2987-2992
-
-
De Silanes, I.L.1
Zhan, M.2
Lal, A.3
Yang, X.4
Gorospe, M.5
-
36
-
-
34547793043
-
Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression
-
Lan, F. et al. Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression. Nature 448, 718-722 (2007).
-
(2007)
Nature
, vol.448
, pp. 718-722
-
-
Lan, F.1
-
37
-
-
33646928455
-
EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming
-
Hirao, K. et al. EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming. J. Biol. Chem. 281, 9650-9658 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 9650-9658
-
-
Hirao, K.1
-
38
-
-
43049128529
-
Tenets of PTEN tumor suppression
-
Salmena, L., Carracedo, A. & Pandolfi, P. P. Tenets of PTEN tumor suppression. Cell 133, 403-414 (2008).
-
(2008)
Cell
, vol.133
, pp. 403-414
-
-
Salmena, L.1
Carracedo, A.2
Pandolfi, P.P.3
-
39
-
-
77953629046
-
Regulation of mRNA translation and stability by microRNAs
-
Fabian, M. R., Sonenberg, N. & Filipowicz, W. Regulation of mRNA translation and stability by microRNAs. Annu. Rev. Biochem. 79, 351-379 (2010).
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 351-379
-
-
Fabian, M.R.1
Sonenberg, N.2
Filipowicz, W.3
-
40
-
-
0030867942
-
Gadd153/Chop10, a potential target gene of the transcriptional repressor ATF3
-
Wolfgang, C. D., Chen, B. P., Martindale, J. L., Holbrook, N. J. & Hai, T. gadd153/Chop10, a potential target gene of the transcriptional repressor ATF3. Mol. Cell Biol. 17, 6700-6707 (1997).
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 6700-6707
-
-
Wolfgang, C.D.1
Chen, B.P.2
Martindale, J.L.3
Holbrook, N.J.4
Hai, T.5
-
41
-
-
39049089691
-
ATF3 protects against renal ischemia-reperfusion injury
-
Yoshida, T. et al. ATF3 protects against renal ischemia-reperfusion injury. J. Am. Soc. Nephrol. 19, 217-224 (2008).
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, pp. 217-224
-
-
Yoshida, T.1
-
42
-
-
1842843855
-
Roles of CHOP/GADD153 in endoplasmic reticulum stress
-
Oyadomari, S. & Mori, M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ. 11, 381-389 (2004).
-
(2004)
Cell Death Differ.
, vol.11
, pp. 381-389
-
-
Oyadomari, S.1
Mori, M.2
-
43
-
-
84870567161
-
MicroRNA-494 reduces ATF3 expression and promotes AKI
-
Lan, Y. F. et al. MicroRNA-494 reduces ATF3 expression and promotes AKI. J. Am. Soc. Nephrol. 23, 2012-2023 (2012).
-
(2012)
J. Am. Soc. Nephrol.
, vol.23
, pp. 2012-2023
-
-
Lan, Y.F.1
-
44
-
-
0024557039
-
The 'initiator' as a transcription control element
-
Smale, S. T. & Baltimore, D. The 'initiator' as a transcription control element. Cell 57, 103-113 (1989).
-
(1989)
Cell
, vol.57
, pp. 103-113
-
-
Smale, S.T.1
Baltimore, D.2
-
45
-
-
33847682663
-
MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors
-
Kato, M. et al. MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors. Proc. Natl Acad. Sci. USA 104, 3432-3437 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 3432-3437
-
-
Kato, M.1
-
46
-
-
79957927211
-
MTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice
-
Inoki, K. et al. mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. J. Clin. Invest. 121, 2181-2196 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2181-2196
-
-
Inoki, K.1
-
47
-
-
84924371283
-
Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy
-
Madhusudhan, T. et al. Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy. Nat. Commun. 6, 6496 (2015).
-
(2015)
Nat. Commun.
, vol.6
, pp. 6496
-
-
Madhusudhan, T.1
-
48
-
-
77952049573
-
Induction of diabetes in aged C57B6 mice results in severe nephropathy: An association with oxidative stress, endoplasmic reticulum stress, and inflammation
-
Wu, J. et al. Induction of diabetes in aged C57B6 mice results in severe nephropathy: an association with oxidative stress, endoplasmic reticulum stress, and inflammation. Am. J. Pathol. 176, 2163-2176 (2010).
-
(2010)
Am. J. Pathol.
, vol.176
, pp. 2163-2176
-
-
Wu, J.1
-
49
-
-
45449087963
-
Apoptosis induced by endoplasmic reticulum stress involved in diabetic kidney disease
-
Liu, G. et al. Apoptosis induced by endoplasmic reticulum stress involved in diabetic kidney disease. Biochem. Biophys. Res. Commun. 370, 651-656 (2008).
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.370
, pp. 651-656
-
-
Liu, G.1
-
50
-
-
84900522497
-
ER stress triggers MCP-1 expression through SET7/9-induced histone methylation in the kidneys of db/db mice
-
Chen, J. et al. ER stress triggers MCP-1 expression through SET7/9-induced histone methylation in the kidneys of db/db mice. Am. J. Physiol. Renal Physiol. 306, F916-F925 (2014).
-
(2014)
Am. J. Physiol. Renal Physiol.
, vol.306
, pp. F916-F925
-
-
Chen, J.1
-
51
-
-
79959951470
-
Metabolic stress promotes renal tubular inflammation by triggering the unfolded protein response
-
Fougeray, S. et al. Metabolic stress promotes renal tubular inflammation by triggering the unfolded protein response. Cell Death Dis. 2, e143 (2011).
-
(2011)
Cell Death Dis.
, vol.2
, pp. e143
-
-
Fougeray, S.1
-
52
-
-
0035966269
-
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
-
Yoshida, H., Matsui, T., Yamamoto, A., Okada, T. & Mori, K. XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 107, 881-891 (2001).
-
(2001)
Cell
, vol.107
, pp. 881-891
-
-
Yoshida, H.1
Matsui, T.2
Yamamoto, A.3
Okada, T.4
Mori, K.5
-
53
-
-
84863270094
-
RNase H-mediated degradation of toxic RNA in myotonic dystrophy type 1
-
Lee, J. E., Bennett, C. F. & Cooper, T. A. RNase H-mediated degradation of toxic RNA in myotonic dystrophy type 1. Proc. Natl Acad. Sci. USA 109, 4221-4226 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 4221-4226
-
-
Lee, J.E.1
Bennett, C.F.2
Cooper, T.A.3
-
54
-
-
84899993786
-
Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth
-
Michalik, K. M. et al. Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth. Circ. Res. 114, 1389-1397 (2014).
-
(2014)
Circ. Res.
, vol.114
, pp. 1389-1397
-
-
Michalik, K.M.1
-
55
-
-
84903979435
-
TCP1 complex proteins interact with phosphorothioate oligonucleotides and can co-localize in oligonucleotide-induced nuclear bodies in mammalian cells
-
Liang, X. H., Shen, W., Sun, H., Prakash, T. P. & Crooke, S. T. TCP1 complex proteins interact with phosphorothioate oligonucleotides and can co-localize in oligonucleotide-induced nuclear bodies in mammalian cells. Nucleic Acids Res. 42, 7819-7832 (2014).
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 7819-7832
-
-
Liang, X.H.1
Shen, W.2
Sun, H.3
Prakash, T.P.4
Crooke, S.T.5
-
56
-
-
33644783770
-
Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy
-
Susztak, K., Raff, A. C., Schiffer, M. & Bottinger, E. P. Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy. Diabetes 55, 225-233 (2006).
-
(2006)
Diabetes
, vol.55
, pp. 225-233
-
-
Susztak, K.1
Raff, A.C.2
Schiffer, M.3
Bottinger, E.P.4
-
57
-
-
84883309399
-
Effect of losartan on prevention and progression of early diabetic nephropathy in American Indians with type 2 diabetes
-
Weil, E. J. et al. Effect of losartan on prevention and progression of early diabetic nephropathy in American Indians with type 2 diabetes. Diabetes 62, 3224-3231 (2013).
-
(2013)
Diabetes
, vol.62
, pp. 3224-3231
-
-
Weil, E.J.1
-
58
-
-
84926429026
-
MicroRNA-21 in glomerular injury
-
Lai, J. Y. et al. MicroRNA-21 in glomerular injury. J. Am. Soc. Nephrol. 26, 805-816 (2015).
-
(2015)
J. Am. Soc. Nephrol.
, vol.26
, pp. 805-816
-
-
Lai, J.Y.1
-
59
-
-
70349487338
-
Hypertrophy and loss of podocytes in diabetic nephropathy
-
Miyauchi, M. et al. Hypertrophy and loss of podocytes in diabetic nephropathy. Intern. Med. 48, 1615-1620 (2009).
-
(2009)
Intern. Med.
, vol.48
, pp. 1615-1620
-
-
Miyauchi, M.1
-
60
-
-
84953331151
-
Glomerular aging and focal global glomerulosclerosis: A podometric perspective
-
Hodgin, J. B. et al. Glomerular aging and focal global glomerulosclerosis: a podometric perspective. J. Am. Soc. Nephrol. 26, 3162-3178 (2015).
-
(2015)
J. Am. Soc. Nephrol.
, vol.26
, pp. 3162-3178
-
-
Hodgin, J.B.1
-
61
-
-
77955364191
-
Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes
-
Marselli, L. et al. Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes. PLoS ONE 5, e11499 (2010).
-
(2010)
PLoS ONE
, vol.5
, pp. e11499
-
-
Marselli, L.1
-
62
-
-
55749105700
-
Proteinuria and hyperglycemia induce endoplasmic reticulum stress
-
Lindenmeyer, M. T. et al. Proteinuria and hyperglycemia induce endoplasmic reticulum stress. J. Am. Soc. Nephrol. 19, 2225-2236 (2008).
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, pp. 2225-2236
-
-
Lindenmeyer, M.T.1
-
63
-
-
84921670676
-
Tribbles homolog 3 attenuates mammalian target of rapamycin complex-2 signaling and inflammation in the diabetic kidney
-
Borsting, E. et al. Tribbles homolog 3 attenuates mammalian target of rapamycin complex-2 signaling and inflammation in the diabetic kidney. J. Am. Soc. Nephrol. 25, 2067-2078 (2014).
-
(2014)
J. Am. Soc. Nephrol.
, vol.25
, pp. 2067-2078
-
-
Borsting, E.1
-
64
-
-
79955752164
-
The endoplasmic reticulum stress response and diabetic kidney disease
-
Cunard, R. & Sharma, K. The endoplasmic reticulum stress response and diabetic kidney disease. Am. J. Physiol. Renal Physiol. 300, F1054-F1061 (2011).
-
(2011)
Am. J. Physiol. Renal Physiol.
, vol.300
, pp. F1054-F1061
-
-
Cunard, R.1
Sharma, K.2
-
65
-
-
20044362239
-
From the periphery of the glomerular capillary wall toward the center of disease: Podocyte injury comes of age in diabetic nephropathy
-
Wolf, G., Chen, S. & Ziyadeh, F. N. From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy. Diabetes 54, 1626-1634 (2005).
-
(2005)
Diabetes
, vol.54
, pp. 1626-1634
-
-
Wolf, G.1
Chen, S.2
Ziyadeh, F.N.3
-
66
-
-
21344452081
-
Role of upstream stimulatory factors in regulation of renal transforming growth factor-beta1
-
Zhu, Y., Casado, M., Vaulont, S. & Sharma, K. Role of upstream stimulatory factors in regulation of renal transforming growth factor-beta1. Diabetes 54, 1976-1984 (2005).
-
(2005)
Diabetes
, vol.54
, pp. 1976-1984
-
-
Zhu, Y.1
Casado, M.2
Vaulont, S.3
Sharma, K.4
-
67
-
-
0036420353
-
Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes
-
Iglesias-de la Cruz, M. C. et al. Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes. Kidney Int. 62, 901-913 (2002).
-
(2002)
Kidney Int.
, vol.62
, pp. 901-913
-
-
Iglesias-De La Cruz, M.C.1
-
68
-
-
84954288448
-
Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker
-
Ju, W. et al. Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker. Sci. Transl. Med. 7, 316ra193 (2015).
-
(2015)
Sci. Transl. Med.
, vol.7
, pp. 316ra193
-
-
Ju, W.1
-
69
-
-
84989843112
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini, Y. & Hochberg, Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. Ser. B (Methodological) 57, 289-300 (1995).
-
(1995)
J. R. Stat. Soc. Ser. B (Methodological)
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
|