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Volumn 59, Issue 4, 2015, Pages 335-342

Lipolysis and lipases in white adipose tissue – An update

Author keywords

Adipose triglyceride lipase; Hormone sensitive lipase; Monoacylglycerol lipase; Perilipin; Triacylglycerol hydrolysis

Indexed keywords

TRIACYLGLYCEROL LIPASE;

EID: 84989229083     PISSN: 23593997     EISSN: 23594292     Source Type: Journal    
DOI: 10.1590/2359-3997000000067     Document Type: Review
Times cited : (137)

References (69)
  • 1
    • 58149528712 scopus 로고    scopus 로고
    • Advances in adipose tissue metabolism
    • Lafontan M. Advances in adipose tissue metabolism. Int J Obes (Lond). 2008;32 Suppl 7:S39-51.
    • (2008) Int J Obes (Lond) , vol.32 , pp. S39-S51
    • Lafontan, M.1
  • 2
    • 0036381998 scopus 로고    scopus 로고
    • Adipose tissue as a buffer for daily lipid flux
    • Frayn KN. Adipose tissue as a buffer for daily lipid flux. Diabetologia. 2002;45(9):1201-10.
    • (2002) Diabetologia , vol.45 , Issue.9 , pp. 1201-1210
    • Frayn, K.N.1
  • 4
    • 23744496757 scopus 로고    scopus 로고
    • Adipose development: From stem cell to adipocyte
    • Otto TC, Lane MD. Adipose development: from stem cell to adipocyte. Crit Rev Biochem Mol Biol. 2005;40(4):229-42.
    • (2005) Crit Rev Biochem Mol Biol , vol.40 , Issue.4 , pp. 229-242
    • Otto, T.C.1    Lane, M.D.2
  • 5
    • 0242363613 scopus 로고    scopus 로고
    • Coordinated upregulation of oxidative pathways and downregulation of lipid biosynthesis underlie obesity resistance in perilipin knockout mice: A microarray gene expression profile
    • Castro-Chavez F, Yechoor VK, Saha PK, Martinez-Botas J, Wooten EC, Sharma S, et al. Coordinated upregulation of oxidative pathways and downregulation of lipid biosynthesis underlie obesity resistance in perilipin knockout mice: a microarray gene expression profile. Diabetes. 2003;52(11):2666-74.
    • (2003) Diabetes , vol.52 , Issue.11 , pp. 2666-2674
    • Castro-Chavez, F.1    Yechoor, V.K.2    Saha, P.K.3    Martinez-Botas, J.4    Wooten, E.C.5    Sharma, S.6
  • 6
    • 0033071156 scopus 로고    scopus 로고
    • Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells
    • Londos C, Brasaemle DL, Schultz CJ, Segrest JP, Kimmel AR. Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells. Semin Cell Dev Biol. 1999;10(1):51-8.
    • (1999) Semin Cell Dev Biol , vol.10 , Issue.1 , pp. 51-58
    • Londos, C.1    Brasaemle, D.L.2    Schultz, C.J.3    Segrest, J.P.4    Kimmel, A.R.5
  • 7
    • 84859631366 scopus 로고    scopus 로고
    • Adipocyte lipases and lipid droplet-associated proteins: Insight from transgenic mouse models
    • Girousse A, Langin D. Adipocyte lipases and lipid droplet-associated proteins: insight from transgenic mouse models. Int J Obes (Lond). 2012;36(4):581-94.
    • (2012) Int J Obes (Lond) , vol.36 , Issue.4 , pp. 581-594
    • Girousse, A.1    Langin, D.2
  • 8
    • 36649015243 scopus 로고    scopus 로고
    • Thematic review series: Adipocyte biology. The perilipin family of structural lipid droplet proteins: Stabilization of lipid droplets and control of lipolysis
    • Brasaemle DL. Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis. J Lipid Res. 2007;48(12):2547-59.
    • (2007) J Lipid Res , vol.48 , Issue.12 , pp. 2547-2559
    • Brasaemle, D.L.1
  • 9
    • 67849128552 scopus 로고    scopus 로고
    • Lipolysis and lipid mobilization in human adipose tissue
    • Lafontan M, Langin D. Lipolysis and lipid mobilization in human adipose tissue. Prog Lipid Res. 2009;48(5):275-97.
    • (2009) Prog Lipid Res , vol.48 , Issue.5 , pp. 275-297
    • Lafontan, M.1    Langin, D.2
  • 11
    • 84858029073 scopus 로고    scopus 로고
    • Clinical review: Regulation of food intake, energy balance, and body fat mass: Implications for the pathogenesis and treatment of obesity
    • Guyenet SJ, Schwartz MW. Clinical review: regulation of food intake, energy balance, and body fat mass: implications for the pathogenesis and treatment of obesity. J Clin Endocrinol Metab. 2012;97(3):745-55.
    • (2012) J Clin Endocrinol Metab , vol.97 , Issue.3 , pp. 745-755
    • Guyenet, S.J.1    Schwartz, M.W.2
  • 12
    • 0033779714 scopus 로고    scopus 로고
    • Free fatty acids and pathogenesis of type 2 diabetes mellitus
    • Bergman RN, Ader M. Free fatty acids and pathogenesis of type 2 diabetes mellitus. Trends Endocrinol Metab. 2000;11(9):351-6.
    • (2000) Trends Endocrinol Metab , vol.11 , Issue.9 , pp. 351-356
    • Bergman, R.N.1    Ader, M.2
  • 15
    • 10344262633 scopus 로고    scopus 로고
    • Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities
    • Jenkins CM, Mancuso DJ, Yan W, Sims HF, Gibson B, Gross RW. Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities. J Biol Chem. 2004;279(47):48968-75.
    • (2004) J Biol Chem , vol.279 , Issue.47 , pp. 48968-48975
    • Jenkins, C.M.1    Mancuso, D.J.2    Yan, W.3    Sims, H.F.4    Gibson, B.5    Gross, R.W.6
  • 16
    • 8744297386 scopus 로고    scopus 로고
    • Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: Ectopic expression of desnutrin increases triglyceride hydrolysis
    • Villena JA, Roy S, Sarkadi-Nagy E, Kim KH, Sul HS. Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis. J Biol Chem. 2004;279(45):47066-75.
    • (2004) J Biol Chem , vol.279 , Issue.45 , pp. 47066-47075
    • Villena, J.A.1    Roy, S.2    Sarkadi-Nagy, E.3    Kim, K.H.4    Sul, H.S.5
  • 18
    • 0036797450 scopus 로고    scopus 로고
    • A futile metabolic cycle activated in adipocytes by antidiabetic agents
    • Guan HP, Li Y, Jensen MV, Newgard CB, Steppan CM, Lazar MA. A futile metabolic cycle activated in adipocytes by antidiabetic agents. Nat Med. 2002;8(10):1122-8.
    • (2002) Nat Med , vol.8 , Issue.10 , pp. 1122-1128
    • Guan, H.P.1    Li, Y.2    Jensen, M.V.3    Newgard, C.B.4    Steppan, C.M.5    Lazar, M.A.6
  • 19
    • 77949325740 scopus 로고    scopus 로고
    • Regulation of adipose tissue lipolysis revisited
    • Bézaire V, Langin D. Regulation of adipose tissue lipolysis revisited. Proc Nutr Soc. 2009;68(4):350-60.
    • (2009) Proc Nutr Soc , vol.68 , Issue.4 , pp. 350-360
    • Bézaire, V.1    Langin, D.2
  • 21
    • 0023901875 scopus 로고
    • Human fat cell beta-adrenergic receptors: Beta-agonist-dependent lipolytic responses and characterization of beta-adrenergic binding sites on human fat cell membranes with highly selective beta 1-antagonists
    • Mauriège P, De Pergola G, Berlan M, Lafontan M. Human fat cell beta-adrenergic receptors: beta-agonist-dependent lipolytic responses and characterization of beta-adrenergic binding sites on human fat cell membranes with highly selective beta 1-antagonists. J Lipid Res. 1988;29(5):587-601.
    • (1988) J Lipid Res , vol.29 , Issue.5 , pp. 587-601
    • Mauriège, P.1    De Pergola, G.2    Berlan, M.3    Lafontan, M.4
  • 22
    • 3142738035 scopus 로고    scopus 로고
    • CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome
    • Yamaguchi T, Omatsu N, Matsushita S, Osumi T. CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome. J Biol Chem. 2004;279(29):30490-7.
    • (2004) J Biol Chem , vol.279 , Issue.29 , pp. 30490-30497
    • Yamaguchi, T.1    Omatsu, N.2    Matsushita, S.3    Osumi, T.4
  • 23
    • 33846029180 scopus 로고    scopus 로고
    • Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism
    • Schweiger M, Schreiber R, Haemmerle G, Lass A, Fledelius C, Jacobsen P, et al. Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism. J Biol Chem. 2006;281(52):40236-41.
    • (2006) J Biol Chem , vol.281 , Issue.52 , pp. 40236-40241
    • Schweiger, M.1    Schreiber, R.2    Haemmerle, G.3    Lass, A.4    Fledelius, C.5    Jacobsen, P.6
  • 24
    • 84870372459 scopus 로고    scopus 로고
    • Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacyl-glycerol-O-acyltransferases
    • Eichmann TO, Kumari M, Haas JT, Farese RV, Zimmermann R, Lass A, et al. Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacyl-glycerol-O-acyltransferases. J Biol Chem. 2012;287(49):41446-57.
    • (2012) J Biol Chem , vol.287 , Issue.49 , pp. 41446-41457
    • Eichmann, T.O.1    Kumari, M.2    Haas, J.T.3    Farese, R.V.4    Zimmermann, R.5    Lass, A.6
  • 25
    • 33646462136 scopus 로고    scopus 로고
    • Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase
    • Haemmerle G, Lass A, Zimmermann R, Gorkiewicz G, Meyer C, Rozman J, et al. Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science. 2006;312(5774):734-7.
    • (2006) Science , vol.312 , Issue.5774 , pp. 734-737
    • Haemmerle, G.1    Lass, A.2    Zimmermann, R.3    Gorkiewicz, G.4    Meyer, C.5    Rozman, J.6
  • 26
    • 67650522935 scopus 로고    scopus 로고
    • Contribution of adipose triglyceride lipase and hormone-sensitive lipase to lipolysis in hMADS adipocytes
    • Bezaire V, Mairal A, Ribet C, Lefort C, Girousse A, Jocken J, et al. Contribution of adipose triglyceride lipase and hormone-sensitive lipase to lipolysis in hMADS adipocytes. J Biol Chem. 2009;284(27):18282-91.
    • (2009) J Biol Chem , vol.284 , Issue.27 , pp. 18282-18291
    • Bezaire, V.1    Mairal, A.2    Ribet, C.3    Lefort, C.4    Girousse, A.5    Jocken, J.6
  • 27
    • 77950620338 scopus 로고    scopus 로고
    • Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids
    • Schoiswohl G, Schweiger M, Schreiber R, Gorkiewicz G, Preiss-Landl K, Taschler U, et al. Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids. J Lipid Res. 2010;51(3):490-9.
    • (2010) J Lipid Res , vol.51 , Issue.3 , pp. 490-499
    • Schoiswohl, G.1    Schweiger, M.2    Schreiber, R.3    Gorkiewicz, G.4    Preiss-Landl, K.5    Taschler, U.6
  • 29
    • 84889686585 scopus 로고    scopus 로고
    • Desnutrin/ATGL activates PPARδ to promote mitochondrial function for insulin secretion in islet β cells
    • Tang T, Abbott MJ, Ahmadian M, Lopes AB, Wang Y, Sul HS. Desnutrin/ATGL activates PPARδ to promote mitochondrial function for insulin secretion in islet β cells. Cell Metab. 2013;18(6):883-95.
    • (2013) Cell Metab , vol.18 , Issue.6 , pp. 883-895
    • Tang, T.1    Abbott, M.J.2    Ahmadian, M.3    Lopes, A.B.4    Wang, Y.5    Sul, H.S.6
  • 31
    • 77951166692 scopus 로고    scopus 로고
    • Mammalian target of rapamycin complex 1 suppresses lipolysis, stimulates lipogenesis, and promotes fat storage
    • Chakrabarti P, English T, Shi J, Smas CM, Kandror KV. Mammalian target of rapamycin complex 1 suppresses lipolysis, stimulates lipogenesis, and promotes fat storage. Diabetes. 2010;59(4):775-81.
    • (2010) Diabetes , vol.59 , Issue.4 , pp. 775-781
    • Chakrabarti, P.1    English, T.2    Shi, J.3    Smas, C.M.4    Kandror, K.V.5
  • 32
    • 79958047295 scopus 로고    scopus 로고
    • Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype
    • Ahmadian M, Abbott MJ, Tang T, Hudak CS, Kim Y, Bruss M, et al. Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype. Cell Metab. 2011;13(6):739-48.
    • (2011) Cell Metab , vol.13 , Issue.6 , pp. 739-748
    • Ahmadian, M.1    Abbott, M.J.2    Tang, T.3    Hudak, C.S.4    Kim, Y.5    Bruss, M.6
  • 34
    • 3142583174 scopus 로고    scopus 로고
    • Oleoylethanolamide stimulates lipolysis by activating the nuclear receptor peroxisome proliferator-activated receptor alpha (PPAR-alpha
    • Guzmán M, Lo Verme J, Fu J, Oveisi F, Blázquez C, Piomelli D. Oleoylethanolamide stimulates lipolysis by activating the nuclear receptor peroxisome proliferator-activated receptor alpha (PPAR-alpha). J Biol Chem. 2004;279(27):27849-54.
    • (2004) J Biol Chem , vol.279 , Issue.27 , pp. 27849-27854
    • Guzmán, M.1    Lo Verme, J.2    Fu, J.3    Oveisi, F.4    Blázquez, C.5    Piomelli, D.6
  • 35
    • 0037983775 scopus 로고    scopus 로고
    • Involvement of AMP-activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes
    • Wu X, Motoshima H, Mahadev K, Stalker TJ, Scalia R, Goldstein BJ. Involvement of AMP-activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes. Diabetes. 2003;52(6):1355-63.
    • (2003) Diabetes , vol.52 , Issue.6 , pp. 1355-1363
    • Wu, X.1    Motoshima, H.2    Mahadev, K.3    Stalker, T.J.4    Scalia, R.5    Goldstein, B.J.6
  • 36
    • 84865420340 scopus 로고    scopus 로고
    • Identification and functional characterization of protein kinase A phosphorylation sites in the major lipolytic protein, adipose triglyceride lipase
    • Pagnon J, Matzaris M, Stark R, Meex RC, Macaulay SL, Brown W, et al. Identification and functional characterization of protein kinase A phosphorylation sites in the major lipolytic protein, adipose triglyceride lipase. Endocrinology. 2012;153(9):4278-89.
    • (2012) Endocrinology , vol.153 , Issue.9 , pp. 4278-4289
    • Pagnon, J.1    Matzaris, M.2    Stark, R.3    Meex, R.C.4    Macaulay, S.L.5    Brown, W.6
  • 37
    • 84902665686 scopus 로고    scopus 로고
    • Identification of a novel phosphorylation site in adipose triglyceride lipase as a regulator of lipid droplet localization
    • Xie X, Langlais P, Zhang X, Heckmann BL, Saarinen AM, Mandarino LJ, et al. Identification of a novel phosphorylation site in adipose triglyceride lipase as a regulator of lipid droplet localization. Am J Physiol Endocrinol Metab. 2014;306(12):E1449-59.
    • (2014) Am J Physiol Endocrinol Metab , vol.306 , Issue.12 , pp. E1449-E1459
    • Xie, X.1    Langlais, P.2    Zhang, X.3    Heckmann, B.L.4    Saarinen, A.M.5    Mandarino, L.J.6
  • 38
    • 77956865739 scopus 로고    scopus 로고
    • Differential control of ATGL-mediated lipid droplet degradation by CGI-58 and G0S2
    • Lu X, Yang X, Liu J. Differential control of ATGL-mediated lipid droplet degradation by CGI-58 and G0S2. Cell Cycle. 2010;9(14):2719-25.
    • (2010) Cell Cycle , vol.9 , Issue.14 , pp. 2719-2725
    • Lu, X.1    Yang, X.2    Liu, J.3
  • 39
    • 84899428316 scopus 로고    scopus 로고
    • Fat-specific Protein 27 (FSP27) Interacts with AdiposeTriglyceride Lipase (ATGL) to Regulate Lipolysis and Insulin Sensitivity in Human Adipocytes
    • Grahn TH, Kaur R, Yin J, Schweiger M, Sharma VM, Lee MJ, et al. Fat-specific Protein 27 (FSP27) Interacts with AdiposeTriglyceride Lipase (ATGL) to Regulate Lipolysis and Insulin Sensitivity in Human Adipocytes. J Biol Chem. 2014;289(17):12029-39.
    • (2014) J Biol Chem , vol.289 , Issue.17 , pp. 12029-12039
    • Grahn, T.H.1    Kaur, R.2    Yin, J.3    Schweiger, M.4    Sharma, V.M.5    Lee, M.J.6
  • 41
    • 0001072302 scopus 로고
    • The production and release of glycerol by adipose tissue incubated in vitro
    • Vaughan M. The production and release of glycerol by adipose tissue incubated in vitro. J Biol Chem. 1962;237:3354-8.
    • (1962) J Biol Chem , vol.237 , pp. 3354-3358
    • Vaughan, M.1
  • 42
    • 2642614548 scopus 로고    scopus 로고
    • Identification of novel phosphorylation sites in hormone-sensitive lipase that are phosphorylated in response to isoproterenol and govern activation properties in vitro
    • Anthonsen MW, Rönnstrand L, Wernstedt C, Degerman E, Holm C. Identification of novel phosphorylation sites in hormone-sensitive lipase that are phosphorylated in response to isoproterenol and govern activation properties in vitro. J Biol Chem. 1998;273(1):215-21.
    • (1998) J Biol Chem , vol.273 , Issue.1 , pp. 215-221
    • Anthonsen, M.W.1    Rönnstrand, L.2    Wernstedt, C.3    Degerman, E.4    Holm, C.5
  • 43
    • 0037085450 scopus 로고    scopus 로고
    • Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis
    • Haemmerle G, Zimmermann R, Hayn M, Theussl C, Waeg G, Wagner E, et al. Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis. J Biol Chem. 2002;277(7):4806-15.
    • (2002) J Biol Chem , vol.277 , Issue.7 , pp. 4806-4815
    • Haemmerle, G.1    Zimmermann, R.2    Hayn, M.3    Theussl, C.4    Waeg, G.5    Wagner, E.6
  • 44
    • 0037241198 scopus 로고    scopus 로고
    • Expression of human hormone-sensitive lipase in white adipose tissue of transgenic mice increases lipase activity but does not enhance in vitro lipolysis
    • Lucas S, Tavernier G, Tiraby C, Mairal A, Langin D. Expression of human hormone-sensitive lipase in white adipose tissue of transgenic mice increases lipase activity but does not enhance in vitro lipolysis. J Lipid Res. 2003;44(1):154-63.
    • (2003) J Lipid Res , vol.44 , Issue.1 , pp. 154-163
    • Lucas, S.1    Tavernier, G.2    Tiraby, C.3    Mairal, A.4    Langin, D.5
  • 46
    • 54449092296 scopus 로고    scopus 로고
    • Identification and functional characterization of adipose-specific phospholipase A2 (AdPLA
    • Duncan RE, Sarkadi-Nagy E, Jaworski K, Ahmadian M, Sul HS. Identification and functional characterization of adipose-specific phospholipase A2 (AdPLA). J Biol Chem. 2008;283(37):25428-36.
    • (2008) J Biol Chem , vol.283 , Issue.37 , pp. 25428-25436
    • Duncan, R.E.1    Sarkadi-Nagy, E.2    Jaworski, K.3    Ahmadian, M.4    Sul, H.S.5
  • 47
    • 84876481542 scopus 로고    scopus 로고
    • Insulin signalling mechanisms for triacylglycerol storage
    • Czech MP, Tencerova M, Pedersen DJ, Aouadi M. Insulin signalling mechanisms for triacylglycerol storage. Diabetologia. 2013;56(5):949-64.
    • (2013) Diabetologia , vol.56 , Issue.5 , pp. 949-964
    • Czech, M.P.1    Tencerova, M.2    Pedersen, D.J.3    Aouadi, M.4
  • 48
    • 36148956577 scopus 로고    scopus 로고
    • Interaction of the adipocyte fatty acid-binding protein with the hormone-sensitive lipase: Regulation by fatty acids and phosphorylation
    • Smith AJ, Thompson BR, Sanders MA, Bernlohr DA. Interaction of the adipocyte fatty acid-binding protein with the hormone-sensitive lipase: regulation by fatty acids and phosphorylation. J Biol Chem. 2007;282(44):32424-32.
    • (2007) J Biol Chem , vol.282 , Issue.44 , pp. 32424-32432
    • Smith, A.J.1    Thompson, B.R.2    Sanders, M.A.3    Bernlohr, D.A.4
  • 49
    • 0030767295 scopus 로고    scopus 로고
    • CDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidases
    • Karlsson M, Contreras JA, Hellman U, Tornqvist H, Holm C. cDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidases. J Biol Chem. 1997;272(43):27218-23.
    • (1997) J Biol Chem , vol.272 , Issue.43 , pp. 27218-27223
    • Karlsson, M.1    Contreras, J.A.2    Hellman, U.3    Tornqvist, H.4    Holm, C.5
  • 50
    • 79955958008 scopus 로고    scopus 로고
    • Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance
    • Taschler U, Radner FP, Heier C, Schreiber R, Schweiger M, Schoiswohl G, et al. Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance. J Biol Chem. 2011;286(20):17467-77.
    • (2011) J Biol Chem , vol.286 , Issue.20 , pp. 17467-17477
    • Taschler, U.1    Radner, F.P.2    Heier, C.3    Schreiber, R.4    Schweiger, M.5    Schoiswohl, G.6
  • 51
    • 33748484029 scopus 로고    scopus 로고
    • PPARgamma agonism increases rat adipose tissue lipolysis, expression of glyceride lipases, and the response of lipolysis to hormonal control
    • Festuccia WT, Laplante M, Berthiaume M, Gelinas Y, Deshaies Y. PPARgamma agonism increases rat adipose tissue lipolysis, expression of glyceride lipases, and the response of lipolysis to hormonal control. Diabetologia. 2006;49(10):2427-36.
    • (2006) Diabetologia , vol.49 , Issue.10 , pp. 2427-2436
    • Festuccia, W.T.1    Laplante, M.2    Berthiaume, M.3    Gelinas, Y.4    Deshaies, Y.5
  • 52
    • 84901326584 scopus 로고    scopus 로고
    • Dissecting adipose tissue lipolysis: Molecular regulation and implications for metabolic disease
    • Nielsen TS, Jessen N, Jørgensen JO, Møller N, Lund S. Dissecting adipose tissue lipolysis: molecular regulation and implications for metabolic disease. J Mol Endocrinol. 2014;52(3):R199-222.
    • (2014) J Mol Endocrinol , vol.52 , Issue.3 , pp. R199-R222
    • Nielsen, T.S.1    Jessen, N.2    Jørgensen, J.O.3    Møller, N.4    Lund, S.5
  • 53
    • 77950607704 scopus 로고    scopus 로고
    • Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins
    • Kimmel AR, Brasaemle DL, McAndrews-Hill M, Sztalryd C, Londos C. Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins. J Lipid Res. 2010;51(3):468-71.
    • (2010) J Lipid Res , vol.51 , Issue.3 , pp. 468-471
    • Kimmel, A.R.1    Brasaemle, D.L.2    McAndrews-Hill, M.3    Sztalryd, C.4    Londos, C.5
  • 56
    • 51449123610 scopus 로고    scopus 로고
    • Up-regulation of mitochondrial activity and acquirement of brown adipose tissuelike property in the white adipose tissue of fsp27 deficient mice
    • Toh SY, Gong J, Du G, Li JZ, Yang S, Ye J, et al. Up-regulation of mitochondrial activity and acquirement of brown adipose tissuelike property in the white adipose tissue of fsp27 deficient mice. PLoS One. 2008;3(8):e2890.
    • (2008) Plos One , vol.3 , Issue.8
    • Toh, S.Y.1    Gong, J.2    Du, G.3    Li, J.Z.4    Yang, S.5    Ye, J.6
  • 57
    • 84863111550 scopus 로고    scopus 로고
    • PPARs: Fatty acid sensors controlling metabolism
    • Poulsen L, Siersbæk M, Mandrup S. PPARs: fatty acid sensors controlling metabolism. Semin Cell Dev Biol. 2012;23(6):631-9.
    • (2012) Semin Cell Dev Biol , vol.23 , Issue.6 , pp. 631-639
    • Poulsen, L.1    Siersbæk, M.2    Mandrup, S.3
  • 59
    • 33646526259 scopus 로고    scopus 로고
    • Effects of fenofibrate on lipid metabolism in adipose tissue of rats
    • Ferreira AV, Parreira GG, Green A, Botion LM. Effects of fenofibrate on lipid metabolism in adipose tissue of rats. Metabolism. 2006;55(6):731-5.
    • (2006) Metabolism , vol.55 , Issue.6 , pp. 731-735
    • Ferreira, A.V.1    Parreira, G.G.2    Green, A.3    Botion, L.M.4
  • 60
    • 80052454265 scopus 로고    scopus 로고
    • ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1
    • Haemmerle G, Moustafa T, Woelkart G, Büttner S, Schmidt A, van de Weijer T, et al. ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1. Nat Med. 2011;17(9):1076-85.
    • (2011) Nat Med , vol.17 , Issue.9 , pp. 1076-1085
    • Haemmerle, G.1    Moustafa, T.2    Woelkart, G.3    Büttner, S.4    Schmidt, A.5    van de Weijer, T.6
  • 61
    • 77953774791 scopus 로고    scopus 로고
    • Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase
    • Chandak PG, Radovic B, Aflaki E, Kolb D, Buchebner M, Fröhlich E, et al. Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase. J Biol Chem. 2010;285(26):20192-201.
    • (2010) J Biol Chem , vol.285 , Issue.26 , pp. 20192-20201
    • Chandak, P.G.1    Radovic, B.2    Aflaki, E.3    Kolb, D.4    Buchebner, M.5    Fröhlich, E.6
  • 62
    • 78751496304 scopus 로고    scopus 로고
    • Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning
    • Ong KT, Mashek MT, Bu SY, Greenberg AS, Mashek DG. Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning. Hepatology. 2011;53(1):116-26.
    • (2011) Hepatology , vol.53 , Issue.1 , pp. 116-126
    • Ong, K.T.1    Mashek, M.T.2    Sy, B.3    Greenberg, A.S.4    Mashek, D.G.5
  • 63
    • 84872401752 scopus 로고    scopus 로고
    • Role of AMP-activated protein kinase in adipose tissue metabolism and inflammation
    • Bijland S, Mancini SJ, Salt IP. Role of AMP-activated protein kinase in adipose tissue metabolism and inflammation. Clin Sci (Lond). 2013;124(8):491-507.
    • (2013) Clin Sci (Lond) , vol.124 , Issue.8 , pp. 491-507
    • Bijland, S.1    Mancini, S.J.2    Salt, I.P.3
  • 64
    • 65349152290 scopus 로고    scopus 로고
    • Prolonged AICAR-induced AMP-kinase activation promotes energy dissipation in white adipocytes: Novel mechanisms integrating HSL and ATGL
    • Gaidhu MP, Fediuc S, Anthony NM, So M, Mirpourian M, Perry RL, et al. Prolonged AICAR-induced AMP-kinase activation promotes energy dissipation in white adipocytes: novel mechanisms integrating HSL and ATGL. J Lipid Res. 2009;50(4):704-15.
    • (2009) J Lipid Res , vol.50 , Issue.4 , pp. 704-715
    • Gaidhu, M.P.1    Fediuc, S.2    Anthony, N.M.3    So, M.4    Mirpourian, M.5    Perry, R.L.6
  • 65
    • 0242290249 scopus 로고    scopus 로고
    • Mutational analysis of the hormone-sensitive lipase translocation reaction in adipocytes
    • Su CL, Sztalryd C, Contreras JA, Holm C, Kimmel AR, Londos C. Mutational analysis of the hormone-sensitive lipase translocation reaction in adipocytes. J Biol Chem. 2003;278(44):43615-9.
    • (2003) J Biol Chem , vol.278 , Issue.44 , pp. 43615-43619
    • Su, C.L.1    Sztalryd, C.2    Contreras, J.A.3    Holm, C.4    Kimmel, A.R.5    Londos, C.6
  • 67
    • 64649096897 scopus 로고    scopus 로고
    • Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesity
    • Ahmadian M, Duncan RE, Varady KA, Frasson D, Hellerstein MK, Birkenfeld AL, et al. Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesity. Diabetes. 2009;58(4):855-66.
    • (2009) Diabetes , vol.58 , Issue.4 , pp. 855-866
    • Ahmadian, M.1    Duncan, R.E.2    Varady, K.A.3    Frasson, D.4    Hellerstein, M.K.5    Birkenfeld, A.L.6
  • 68
    • 59649089306 scopus 로고    scopus 로고
    • AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency
    • Jaworski K, Ahmadian M, Duncan RE, Sarkadi-Nagy E, Varady KA, Hellerstein MK, et al. AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency. Nat Med. 2009;15(2):159-68.
    • (2009) Nat Med , vol.15 , Issue.2 , pp. 159-168
    • Jaworski, K.1    Ahmadian, M.2    Duncan, R.E.3    Sarkadi-Nagy, E.4    Varady, K.A.5    Hellerstein, M.K.6
  • 69
    • 4143094816 scopus 로고    scopus 로고
    • Metabolic adaptations in the absence of perilipin: Increased betaoxidation and decreased hepatic glucose production associated with peripheral insulin resistance but normal glucose tolerance in perilipin-null mice
    • Saha PK, Kojima H, Martinez-Botas J, Sunehag AL, Chan L. Metabolic adaptations in the absence of perilipin: increased betaoxidation and decreased hepatic glucose production associated with peripheral insulin resistance but normal glucose tolerance in perilipin-null mice. J Biol Chem. 2004;279(34):35150-8.
    • (2004) J Biol Chem , vol.279 , Issue.34 , pp. 35150-35158
    • Saha, P.K.1    Kojima, H.2    Martinez-Botas, J.3    Sunehag, A.L.4    Chan, L.5


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